CN103550548B - 一种治疗便秘的中药组合物 - Google Patents
一种治疗便秘的中药组合物 Download PDFInfo
- Publication number
- CN103550548B CN103550548B CN201310510647.4A CN201310510647A CN103550548B CN 103550548 B CN103550548 B CN 103550548B CN 201310510647 A CN201310510647 A CN 201310510647A CN 103550548 B CN103550548 B CN 103550548B
- Authority
- CN
- China
- Prior art keywords
- radix
- chinese medicine
- constipation
- rhizoma
- fructus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000003814 drug Substances 0.000 title claims abstract description 46
- 206010010774 Constipation Diseases 0.000 title claims abstract description 35
- 239000000203 mixture Substances 0.000 title claims abstract description 22
- 108010052008 colla corii asini Proteins 0.000 claims abstract description 12
- 239000002994 raw material Substances 0.000 claims abstract description 12
- 241000756943 Codonopsis Species 0.000 claims abstract description 10
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 10
- 210000000582 Semen Anatomy 0.000 claims abstract description 10
- 238000004080 punching Methods 0.000 claims description 6
- 230000000694 effects Effects 0.000 abstract description 26
- 230000001737 promoting Effects 0.000 abstract description 10
- 230000001717 pathogenic Effects 0.000 abstract description 9
- 210000001124 Body Fluids Anatomy 0.000 abstract description 7
- 239000010839 body fluid Substances 0.000 abstract description 7
- 210000000952 Spleen Anatomy 0.000 abstract description 6
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 238000010926 purge Methods 0.000 abstract description 6
- 210000004185 Liver Anatomy 0.000 abstract description 5
- 210000002784 Stomach Anatomy 0.000 abstract description 5
- 235000013305 food Nutrition 0.000 abstract description 5
- 230000001105 regulatory Effects 0.000 abstract description 5
- 210000003734 Kidney Anatomy 0.000 abstract description 4
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 210000004369 Blood Anatomy 0.000 description 15
- 239000008280 blood Substances 0.000 description 15
- 230000013872 defecation Effects 0.000 description 11
- 201000010099 disease Diseases 0.000 description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances data:image/svg+xml;base64,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 data:image/svg+xml;base64,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 O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 210000003608 Feces Anatomy 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 4
- 229940079593 drugs Drugs 0.000 description 4
- 231100000486 side effect Toxicity 0.000 description 4
- 230000001225 therapeutic Effects 0.000 description 4
- 208000004880 Polyuria Diseases 0.000 description 3
- 208000001431 Psychomotor Agitation Diseases 0.000 description 3
- 206010038743 Restlessness Diseases 0.000 description 3
- 230000035619 diuresis Effects 0.000 description 3
- 230000000968 intestinal Effects 0.000 description 3
- 230000025627 positive regulation of urine volume Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 208000004981 Coronary Disease Diseases 0.000 description 2
- 206010013781 Dry mouth Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 210000004072 Lung Anatomy 0.000 description 2
- 231100000614 Poison Toxicity 0.000 description 2
- 231100000765 Toxin Toxicity 0.000 description 2
- 208000005946 Xerostomia Diseases 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 201000001084 cerebrovascular disease Diseases 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
- 201000008739 coronary artery disease Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 210000004914 menses Anatomy 0.000 description 2
- 230000005906 menstruation Effects 0.000 description 2
- 238000010025 steaming Methods 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 206010000496 Acne Diseases 0.000 description 1
- 206010001897 Alzheimer's disease Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000008787 Cardiovascular Disease Diseases 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 210000004347 Intestinal Mucosa Anatomy 0.000 description 1
- 210000000936 Intestines Anatomy 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 206010030302 Oliguria Diseases 0.000 description 1
- 241000283898 Ovis Species 0.000 description 1
- KJFMBFZCATUALV-UHFFFAOYSA-N Phenolphthalein Chemical compound data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='300px' height='300px' viewBox='0 0 300 300'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='300.0' height='300.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 116.6,142.3 L 79.4,137.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 112.0,134.1 L 85.9,130.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-6 atom-0' d='M 139.4,112.5 L 116.6,142.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 79.4,137.4 L 65.0,102.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 65.0,102.8 L 52.8,101.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 52.8,101.2 L 40.6,99.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-2 atom-4' d='M 65.0,102.8 L 87.8,73.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-2 atom-4' d='M 74.3,102.8 L 90.3,82.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 87.8,73.0 L 125.0,77.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 125.0,77.8 L 139.4,112.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 120.2,85.9 L 130.3,110.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 139.4,112.5 L 176.6,117.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 176.6,117.3 L 167.9,153.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-7 atom-15' d='M 176.6,117.3 L 212.0,129.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-23 atom-7' d='M 177.1,95.7 L 176.8,106.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-23 atom-7' d='M 176.8,106.5 L 176.6,117.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 167.9,153.8 L 131.9,164.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 164.6,162.6 L 139.4,170.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-8 atom-14' d='M 167.9,153.8 L 195.1,179.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 131.9,164.5 L 123.2,201.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 123.2,201.0 L 150.4,226.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 132.4,199.4 L 151.5,217.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 150.4,226.8 L 147.6,238.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 147.6,238.7 L 144.8,250.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-11 atom-13' d='M 150.4,226.8 L 186.4,216.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 186.4,216.1 L 195.1,179.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 180.4,208.9 L 186.5,183.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 212.0,129.8 L 226.4,164.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 221.0,132.1 L 231.1,156.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-20 atom-15' d='M 234.8,100.0 L 212.0,129.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 226.4,164.4 L 263.6,169.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-17 atom-18' d='M 263.6,169.3 L 286.4,139.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-17 atom-18' d='M 261.0,160.3 L 277.0,139.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 286.4,139.5 L 272.0,104.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 272.0,104.8 L 234.8,100.0' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 265.4,111.6 L 239.4,108.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 234.8,100.0 L 213.5,69.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 217.0,70.3 L 220.5,60.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 220.5,60.4 L 224.0,50.5' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 209.9,67.8 L 213.4,57.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 213.4,57.9 L 216.9,48.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 213.5,69.1 L 201.8,72.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 201.8,72.6 L 190.1,76.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:2.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='13.6' y='105.4' class='atom-3' style='font-size:15px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='23.2' y='105.4' class='atom-3' style='font-size:15px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='137.2' y='270.8' class='atom-12' style='font-size:15px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='147.6' y='270.8' class='atom-12' style='font-size:15px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='221.4' y='41.2' class='atom-22' style='font-size:15px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='173.0' y='87.3' class='atom-23' style='font-size:15px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 data:image/svg+xml;base64,<?xml version='1.0' encoding='iso-8859-1'?>
<svg version='1.1' baseProfile='full'
              xmlns='http://www.w3.org/2000/svg'
                      xmlns:rdkit='http://www.rdkit.org/xml'
                      xmlns:xlink='http://www.w3.org/1999/xlink'
                  xml:space='preserve'
width='85px' height='85px' viewBox='0 0 85 85'>
<!-- END OF HEADER -->
<rect style='opacity:1.0;fill:#FFFFFF;stroke:none' width='85.0' height='85.0' x='0.0' y='0.0'> </rect>
<path class='bond-0 atom-0 atom-1' d='M 33.3,39.7 L 22.9,38.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-0 atom-0 atom-1' d='M 32.0,37.4 L 24.7,36.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-23 atom-6 atom-0' d='M 39.6,31.4 L 33.3,39.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-1 atom-1 atom-2' d='M 22.9,38.4 L 18.9,28.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 18.9,28.7 L 14.7,28.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-2 atom-2 atom-3' d='M 14.7,28.2 L 10.5,27.6' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-2 atom-4' d='M 18.9,28.7 L 25.2,20.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-3 atom-2 atom-4' d='M 21.5,28.7 L 25.9,22.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-4 atom-4 atom-5' d='M 25.2,20.4 L 35.6,21.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 35.6,21.7 L 39.6,31.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-5 atom-5 atom-6' d='M 34.3,24.0 L 37.1,30.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-6 atom-6 atom-7' d='M 39.6,31.4 L 50.0,32.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-7 atom-7 atom-8' d='M 50.0,32.8 L 47.6,42.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-14 atom-7 atom-15' d='M 50.0,32.8 L 59.9,36.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-23 atom-7' d='M 50.2,25.5 L 50.1,29.2' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-24 atom-23 atom-7' d='M 50.1,29.2 L 50.0,32.8' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 47.6,42.9 L 37.5,45.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-8 atom-8 atom-9' d='M 46.7,45.4 L 39.6,47.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-25 atom-8 atom-14' d='M 47.6,42.9 L 55.2,50.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-9 atom-9 atom-10' d='M 37.5,45.9 L 35.1,56.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 35.1,56.1 L 42.7,63.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-10 atom-10 atom-11' d='M 37.7,55.7 L 43.0,60.7' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 42.7,63.3 L 41.7,67.4' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-11 atom-11 atom-12' d='M 41.7,67.4 L 40.8,71.4' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-12 atom-11 atom-13' d='M 42.7,63.3 L 52.7,60.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 52.7,60.3 L 55.2,50.1' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-13 atom-13 atom-14' d='M 51.1,58.3 L 52.8,51.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 59.9,36.2 L 63.9,45.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-15 atom-15 atom-16' d='M 62.4,36.9 L 65.2,43.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-26 atom-20 atom-15' d='M 66.2,27.9 L 59.9,36.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-16 atom-16 atom-17' d='M 63.9,45.9 L 74.3,47.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-17 atom-18' d='M 74.3,47.3 L 80.6,38.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-17 atom-17 atom-18' d='M 73.6,44.7 L 78.0,38.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-18 atom-18 atom-19' d='M 80.6,38.9 L 76.6,29.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 76.6,29.3 L 66.2,27.9' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-19 atom-19 atom-20' d='M 74.8,31.1 L 67.5,30.2' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-20 atom-20 atom-21' d='M 66.2,27.9 L 60.3,19.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 61.3,19.6 L 62.4,16.3' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 62.4,16.3 L 63.6,13.0' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 59.3,19.0 L 60.5,15.6' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-21 atom-21 atom-22' d='M 60.5,15.6 L 61.6,12.3' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 60.3,19.3 L 56.3,20.5' style='fill:none;fill-rule:evenodd;stroke:#3B4143;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<path class='bond-22 atom-21 atom-23' d='M 56.3,20.5 L 52.3,21.7' style='fill:none;fill-rule:evenodd;stroke:#E84235;stroke-width:1.0px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1' />
<text x='2.8' y='30.3' class='atom-3' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='6.7' y='30.3' class='atom-3' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='38.5' y='76.5' class='atom-12' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='42.6' y='76.5' class='atom-12' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >H</text>
<text x='62.0' y='12.4' class='atom-22' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
<text x='48.5' y='25.3' class='atom-23' style='font-size:6px;font-style:normal;font-weight:normal;fill-opacity:1;stroke:none;font-family:sans-serif;text-anchor:start;fill:#E84235' >O</text>
</svg>
 C1=CC(O)=CC=C1C1(C=2C=CC(O)=CC=2)C2=CC=CC=C2C(=O)O1 KJFMBFZCATUALV-UHFFFAOYSA-N 0.000 description 1
- 206010039966 Senile dementia Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 210000002700 Urine Anatomy 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000003187 abdominal Effects 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 230000001166 anti-perspirant Effects 0.000 description 1
- 239000003213 antiperspirant Substances 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000002650 habitual Effects 0.000 description 1
- 201000010238 heart disease Diseases 0.000 description 1
- 230000023597 hemostasis Effects 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000003340 mental Effects 0.000 description 1
- 230000003020 moisturizing Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 210000000056 organs Anatomy 0.000 description 1
- 230000003119 painkilling Effects 0.000 description 1
- 244000052769 pathogens Species 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000035943 smell Effects 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000001502 supplementation Effects 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000002936 tranquilizing Effects 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
Abstract
本发明涉及一种治疗便秘的中药组合物，其中药原料及重量份配比为：其中药原料及重量份配比为：生地10-40份、大黄5-20份、当归10-30份、白芍5-20份、黄柏5-25份、知母5-25份、栀子5-25份、地骨皮10-30份、桃仁5-20份、山茱萸5-25份、云苓5-20份、泽泻5-25份、丹参5-20份、女贞子10-30份、芦根5-25份、熟地5-20份、桑椹子10-30份、党参5-20份、阿胶5-10份和甘草5-15份。本发明的中药组合物具有滋肝补肾、健脾和胃、泻火消积、养阴生津、润肠通便的功效，其治疗便秘疗效显著，作用可靠；其组分药源广、配制简便、无毒副作用。
Description
技术领域
[0001] 本发明涉及一种传统草药的未确定结构的医药配制品，尤其是一种治疗便秘的中药组合物。
背景技术
[0002] 便秘是以排便间隔时间延长，大便干结难解为主要临床表现的病症，为临床常见病，多发病，患者人群极为广泛。因宿便压迫肠壁，使肠粘膜受伤，肠蠕动变慢，导致习惯性便秘和顽固性便秘，主要症状为3~5天排便一次，粪便干硬，排出困难。宿便产生的臭气不但导致口臭和臭屁，更主要的是宿便产生22种毒素会被肠道反复吸收，通过血液循环到达人体的各个部位，导致面色晦暗、皮肤粗糙、毛孔扩张、褐斑、痤疮、细小皱纹、肥胖、乏力、烦躁等，特别是宿便中的毒素进入血液，使中老年人容易出现高血压、心脏病、半身不遂、老年痴呆等，同时还会加重中老年人的心脑血管疾病。便秘对高血压、冠心病人来说是十分危险的，有时会因排便异常用力而突发脑血管意外，冠心病加重，甚至死亡。目前，对于便秘一般都是通过服用缓泻药、泻药(果导片、大黄、蕃泄叶)来解决，如长期服用，不但会产生耐药性，降低治疗效果，而且还存在着不同程度的副作用，给病人带来极大的痛苦。
[0003] 中医认为，便秘主要由气阴不足，燥热内结，腑气不畅，津液耗伤和脾肾虚寒所引起。
[0004] 根据中医理论，针对便秘的发病机理，采用泻火消积、润肠通便的治法，进行辩证的组方配伍，以达到标本兼治的目的。
发明内容
[0005] 为了克服现有技术中服用缓泻药、泻药治疗便秘存在治标不治本及副作用大的不足，本发明提供一种配制简便、成本低、疗效显著、无副作用的治疗便秘的中药组合物。
[0006] 本发明解决其技术问题所采用的技术方案是:一种治疗便秘的中药组合物，其特征在于:其中药原料及重量份配比为:生地10-40份、大黄5-20份、当归10-30份、白芍5-20份、黄柏5-25份、知母5-25份、栀子5-25份、地骨皮10-30份、桃仁5_20份、山茱萸5_25份、云苓5-20份、泽泻5-25份、丹参5-20份、女贞子10_30份、芦根5_25份、熟地5_20份、桑椹子10-30份、党参5-20份、阿胶5-10份和甘草5_15份。
[0007] 本发明的优选技术方案是:一种治疗便秘的中药组合物，其特征在于:其中药原料及重量份配比为:生地30份、大黄10份、当归20份、白芍12份、黄柏15份、知母15份、栀子15份、地骨皮20份、桃仁12份、山茱萸15份、云苳12份、泽湾15份、丹参12份、女贞子20份、芦根15份、熟地12份、桑椹子20份、党参12份、阿胶7份和甘草10份。
[0008] 本发明中药组合物是在传统中医理论和临床经验指导下，精选药物组方。本发明中药组合物中:生地具有清热凉血、养阴生津、止痛调经的功效；大黄具有泻火消积、清热解毒、凉血止血、祛瘀止咳的功效；当归具有补血活血、调经止痛，润肠通便的功效；白芍具有养血柔肝、缓中止痛、敛阴收汗的功效；黄柏具有清热燥湿、泻火除蒸、解毒疗疮的功效；知母具有清热泻火、生津润燥的功效；栀子具有泻火除烦、清热利湿、凉血解毒的功效；地骨皮具有凉血除蒸、清肺降火的功效；桃仁具有活血祛瘀、润肠通便的功效；山茱萸具有补益肝肾、涩精固脱的功效；云苓具有益气安神、健脾和胃、祛除湿热、行水止泄的功效；泽泻具有利水渗湿、泄热通淋的功效；丹参具有活血调经、祛瘀止痛、凉血消痈、清心除烦、养血安神的功效；女贞子具有滋补肝肾、益阴养血的功效；芦根具有清热生津、除烦、止呕、利尿的功效；熟地具有补血养阴、填精益髓的功效；桑椹子具有滋阴补血、生津润肠的功效；党参具有补中益气、健脾益肺的功效；阿胶具有补血、止血、滋阴润燥的功效；甘草具有补脾益气、清热解毒、祛痰止咳、调和诸药的功效。本发明精选药物组方，其药物组分经辩证配伍，在作用上相互佐助，共奏滋肝补肾、健脾和胃、泻火消积、养阴生津、润肠通便的功效，对便秘的治疗达到标本兼治。
[0009] 本发明组合物的组分均采用天然的中药原料，其配制简便、药源广、成本低。本发明遵循中医的处方用药原则，各种组分药物采用水煎服用。经临床应用验证，其疗效显著可靠，药性平和，未出现毒副作用，有效率达95%，治愈率65%。
具体实施方式
[0010] 下面结合实施例对本发明作进一步说明。
[0011] 实施例1
[0012] 一种治疗便秘的中药组合物，其中药原料及重量配比为:生地30g、大黄10g、当归20g、白苟12g、黄柏15g、知母15g、栀子15g、地骨皮20g、桃仁12g、山茱萸15g、云苳12g、泽泻15g、丹参12g、女贞子20g、芦根15g、熟地12g、桑椹子20g、党参12g、阿胶(烊冲)7g和甘草 1go
[0013] 实施例2
[0014] 一种治疗便秘的中药组合物，其中药原料及重量配比为:生地15g、大黄20g、当归10g、白苟15g、黄柏5g、知母25g、栀子10g、地骨皮30g、桃仁5g、山茱萸20g、云苳10g、泽湾20g、丹参5g、女贞子30g、芦根10g、熟地20g、桑椹子10g、党参20g、阿胶(烊冲)9g和甘草12g0
[0015] 实施例3
[0016] 一种治疗便秘的中药组合物，其中药原料及重量配比为:生地20g、大黄12g、当归25g、白苟20g、黄柏12g、知母20g、栀子5g、地骨皮15g、桃仁10g、山茱萸5g、云苳20g、泽湾12g、丹参15g、女贞子25g、芦根20g、熟地5g、桑椹子15g、党参10g、阿胶(烊冲)5g和甘草5g。
[0017] 实施例4
[0018] 一种治疗便秘的中药组合物，其中药原料及重量配比为:生地40g、大黄15g、当归30g、白苟5g、黄柏20g、知母5g、栀子25g、地骨皮10g、桃仁20g、山茱萸25g、云苳5g、泽湾25g、丹参20g、女贞子10g、芦根5g、熟地15g、桑椹子30g、党参5g、阿胶(烊冲)1g和甘草15g。
[0019] 实施例5
[0020] 一种治疗便秘的中药组合物，其中药原料及重量配比为:生地25g、大黄5g、当归15g、白苟10g、黄柏25g、知母10g、栀子20g、地骨皮25g、桃仁15g、山茱萸10g、云苳15g、泽泻20g、丹参10g、女贞子15g、芦根25g、熟地10g、桑椹子25g、党参15g、阿胶(烊冲)8g和甘草6g0
[0021] 本发明实施例中的中药组合物除阿胶外按常规的水煎法制取药剂。具体方法如下:将组方的中药原料放入容器中，加冷水漫过药面，浸泡15〜20分钟，再加水没过药面约8厘米，进行第一次煎煮，未沸前采用武火煎煮，沸后用文火煎煮20〜30分钟；第二次煎煮，加水没过药面约6厘米，水沸后煎煮15〜20分钟。两次煎煮取汁，合并。
[0022] 本发明以实施例1所给出的一种治疗便秘的中药组合物，做临床疗效总结如下:
[0023] 一、一般性资料:本中药组合物应用于临床观察病例80例，男42例，女38例，年龄40〜75岁。
[0024] 二、诊断标准:参照国家中医药管理局颁发的《中医病证诊断疗效标准》中便秘的诊断标准:
[0025] 1、排便时间延长，二天以上一次，粪便干燥坚硬；
[0026] 2、重者大便艰难，干燥如栗，可伴少腹胀急，神倦乏力，胃纳减退等症；
[0027] 3、排除肠道器质性疾病。
[0028] 三、用法用量:临床应用时，一日一剂，水煎两遍取汁约400ml，分早、晚两次空腹温服。六天为一疗程。治疗期间忌生冷辛辣刺激之物。
[0029] 四、疗效标准:参照国家中医药管理局颁发的《中医病证诊断疗效标准》中便秘的疗效标准:
[0030] (I)痊愈:2天以内排便I次，便质转润，解时通畅，短期无复发；
[0031] (2)有效:3天以内排便，便质转润，排便欠畅；
[0032] (3)无效；症状无改善。
[0033] 五、治疗效果:该临床观察病例中，服药2-5个疗程，痊愈52例，随访未见复发；有效24例，无效4例。治疗期间未发生毒副作用。
[0034] 六、典型病例:
[0035]病例 1:
[0036] 张某，男，37岁。患者自述有便秘病史3年，排便困难，粪便干燥坚硬，每3-4天排便一次，并伴有口苦口干，小便短赤。诊见:舌红苔黄，脉滑数。服用本发明中药组合物制备的药剂2个疗程，2天以内排便I次，便质转润，解时通畅，治愈。随访半年无复发。
[0037]病例 2:
[0038] 汤某，女，53岁。病症:便秘达3年之久，大便干结，状如羊屎，口干少津，神疲纳差。经多家医院治疗效果不佳。诊见:舌红，苔少，脉细小数。服用本发明中药组合物制备的药剂2个疗程，所有症状得到缓解；继续服用2个疗程，所有症状完全消失，治愈。
Claims (1)
1.一种治疗便秘的中药组合物，其特征在于:其中药原料及重量配比为:生地黄30g、大黄10g、当归20g、白苟12g、黄柏15g、知母15g、栀子15g、地骨皮20g、桃仁12g、山茱萸15g、云茯苓12g、泽泻15g、丹参12g、女贞子20g、芦根15g、熟地黄12g、桑椹20g、党参12g、阿胶7g和甘草1g ;其中，所述的阿胶的服用方法为烊冲。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310510647.4A CN103550548B (zh) | 2013-10-26 | 2013-10-26 | 一种治疗便秘的中药组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310510647.4A CN103550548B (zh) | 2013-10-26 | 2013-10-26 | 一种治疗便秘的中药组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103550548A CN103550548A (zh) | 2014-02-05 |
| CN103550548B true CN103550548B (zh) | 2015-11-04 |
Family
ID=50005020
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310510647.4A Expired - Fee Related CN103550548B (zh) | 2013-10-26 | 2013-10-26 | 一种治疗便秘的中药组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103550548B (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103920014A (zh) * | 2014-04-21 | 2014-07-16 | 郑家林 | 一种调理肠胃、治疗便秘的中药酒 |
| CN104587312A (zh) * | 2015-02-15 | 2015-05-06 | 孙红梅 | 一种治疗便秘的中药组合物 |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015667A (zh) * | 2006-04-24 | 2007-08-15 | 李清成 | 一种治疗便秘胀满的中药 |
| CN101273745A (zh) * | 2008-03-12 | 2008-10-01 | 周克家 | 润肠保健茶 |
| CN102008662A (zh) * | 2010-04-27 | 2011-04-13 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗便秘的中药组合物及其制备方法 |
| CN102697843A (zh) * | 2012-05-30 | 2012-10-03 | 肖梅芬 | 一种清肠通便排毒养颜保健品及其制备方法 |
| CN102697947A (zh) * | 2012-05-16 | 2012-10-03 | 江苏苏南药业实业有限公司 | 一种治疗便秘的中药配方 |
| CN102895400A (zh) * | 2012-10-16 | 2013-01-30 | 祝雨婷 | 治疗老年糖尿病性便秘的中药汤剂 |
-
2013
- 2013-10-26 CN CN201310510647.4A patent/CN103550548B/zh not_active Expired - Fee Related
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101015667A (zh) * | 2006-04-24 | 2007-08-15 | 李清成 | 一种治疗便秘胀满的中药 |
| CN101273745A (zh) * | 2008-03-12 | 2008-10-01 | 周克家 | 润肠保健茶 |
| CN102008662A (zh) * | 2010-04-27 | 2011-04-13 | 泰一和浦（北京）中医药研究院有限公司 | 一种治疗便秘的中药组合物及其制备方法 |
| CN102697947A (zh) * | 2012-05-16 | 2012-10-03 | 江苏苏南药业实业有限公司 | 一种治疗便秘的中药配方 |
| CN102697843A (zh) * | 2012-05-30 | 2012-10-03 | 肖梅芬 | 一种清肠通便排毒养颜保健品及其制备方法 |
| CN102895400A (zh) * | 2012-10-16 | 2013-01-30 | 祝雨婷 | 治疗老年糖尿病性便秘的中药汤剂 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103550548A (zh) | 2014-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103007216B (zh) | 一种治疗慢性腹泻的中药组合物 | |
| CN103349756B (zh) | 一种治疗抑郁症的中药组合物 | |
| CN103463404B (zh) | 一种治疗肝肾阴虚的中药组合物 | |
| CN102430079B (zh) | 一种治疗淋证的中药组合物 | |
| CN102670961B (zh) | 一种治疗中老年习惯性便秘的中药 | |
| CN103394057B (zh) | 一种治疗泄泻的中药组合物 | |
| CN103463587A (zh) | 一种治疗脾胃虚寒的中药组合物 | |
| CN103550687B (zh) | 一种治疗肝肾阴虚的中药组合物 | |
| CN104606560A (zh) | 一种治疗淋证的中药组合物 | |
| CN104288496A (zh) | 一种治疗便秘的中药组合物 | |
| CN102988616B (zh) | 一种治疗贫血的中药组合物 | |
| CN103550728B (zh) | 一种治疗肝胆湿热引起胁痛的中药组合物 | |
| CN103550548B (zh) | 一种治疗便秘的中药组合物 | |
| CN102784332A (zh) | 一种治疗脉管炎的药物 | |
| CN103251800B (zh) | 一种治疗过敏性皮炎的中药组合物 | |
| CN104173933A (zh) | 一种治疗抑郁症的中药组合物 | |
| CN103705684A (zh) | 一种治疗淋症的中药组合物 | |
| CN100998728A (zh) | 一种治疗阳虚型便秘的内服中药 | |
| CN103263611A (zh) | 一种治疗结肠炎的中药组合物 | |
| CN103028063B (zh) | 一种治疗肾病的中药组合物 | |
| CN103536856B (zh) | 一种治疗少腹痛的中药组合物 | |
| CN101985027A (zh) | 治疗肝硬化的中草药 | |
| CN105663659A (zh) | 一种治疗便秘的中药组合物 | |
| CN105106913A (zh) | 一种治疗脾肾阳虚型慢性结肠炎的中药组合物 | |
| CN105250956A (zh) | 一种治疗结肠炎的中药组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| C06 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20151009 Address after: 264309 Shidao, Shandong, China, the new city of Rongcheng Double Road East, No. 199 Applicant after: Chi Rong Address before: 264300 Rongcheng City, Shandong Province Cultural East Road, No. 20, No. Applicant before: Rongcheng Research Institute of Scientific & Technical Information |
|
| CB03 | Change of inventor or designer information |
Inventor after: Chi Rong Inventor after: Chi Rongsun Sheng Bo Inventor before: Sun Shengbo |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data | ||
| GR01 | Patent grant | ||
| C14 | Grant of patent or utility model | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20151104 Termination date: 20161026 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |