CN102125179A - Soft capsule nutritional supplement applicable to piglets and preparation method thereof - Google Patents
Soft capsule nutritional supplement applicable to piglets and preparation method thereof Download PDFInfo
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Abstract
The invention provides soft capsule nutritional supplement applicable to piglets and a preparation method thereof. The preparation method comprises the following steps of: preparing a capsule shell from raw materials of gelatin, glycerol, alpha-modified starch, starch, water, saccharin sodium and the like; preparing a filling core material from feed vitamin, trace elements, enzyme, probiotics, active peptide, organic acid and emulsified oil and fat; and filling the filling core material into the capsule shell to prepare the finished product. The preparation process and the using method are simple. The soft capsule nutritional supplement can be dissolved in an oral cavity of the piglet quickly, releases nutritional elements, achieves effects of quickly absorbing the nutritional elements and completely supplementing nutrients needed by the piglets, and can reduce or avoid stress reaction caused by nutritional supplementation through intramuscular injection and oral administration.
Description
Technical field
What the present invention relates to is the nutritional supplement that sucking pig is used, and what be specifically related to is soft capsule nutritional supplement that is applicable to newborn piglet and preparation method thereof, belongs to veterinary drug and field of feed.
Background technology
Breast piglet birth is to a week, and mainly by the breast milk growth of nourishing and growing, but some nutrition such as iron, arginine, vitamin etc. are depended merely on the breast milk nutrition newborn piglet demand of often can not being satisfied with.Simultaneously, sucking pig disease resistance, more digestant products such as probio, organic acid, digestive ferment etc. also need in time to replenish.The pellet because the birth of newborn piglet can not be searched for food to the week all adopts intramuscular injection or oral cavity to gavage above-mentioned nutrition, particularly iron preparation is provided in the production practices, the piglet birth intramuscular injection benefit iron that was about to begin in 3 days.Facts have proved that intramuscular injection makes sucking pig produce stress reaction more, reduces immunity; And the oral cavity gavages both inconveniences, pollutes easily again, wastes.Therefore, searching newborn piglet nutritional supplementation method convenient, health is extremely urgent.
The soft capsule product comes out for many years at human medicine and health products, is characterized in that particle is big, and diameter is many more than 10mm, and is big as peanut, little of mung bean, generally once oral 1-2 grain; It is filled core and is chyle fat suspension or paste.Medical treatment and health care practice show that after sick and weak crowd took the soft capsule product, active ingredient can discharge in the capsule in enteron aisle, medical treatment and health-care efficacy are definite, satisfactory.But veterinary drug and field of fodder still do not have soft capsule development report or product at present, and the micro-capsule bag of field of fodder is early had report, have product to come out yet.But the two has essential distinction to the micro-capsule bag of field of fodder by the soft capsule of and field of health care products medical with the mankind, fundamentally is exactly two kinds of products.As everyone knows, feed microcomponent such as vitamin, trace element, enzyme, probio, active peptide, organic acid and medicament microcapsule coating technique are also ripe, how to adopt in the production practices.At present, the technical essential of feed micro-capsule bag quilt mainly is that bag is little by particle, and diameter is between 0.01 μ m～1000 μ m, and how below 40 orders, perusal almost is very thin powder, animal thousands of and even tens thousand of grains of once searching for food; It is filled core and is solid tiny particle; And the newborn piglet of can not directly throwing something and feeding, all be to be mixed in the feed to throw something and feed, the capsulating material taste does not have sweet taste.
In addition, the micro-capsule of the soft capsule of human medicine of soft capsule and field of health care products and field of fodder wraps in essential distinction is also arranged on the production technology.Medicine soft capsule technology is to suppress the glue shell earlier, insert core again and make capsule, and mostly feed micro-capsule bag is coated body and bag are mixed together stirring by glue (thing) by technology, oven dry back formation micro-capsule bag quilt.
Through reading up the literature, use product scope in field of fodder or sucking pig, have not yet to see the soft capsule particle diameter and be emulsified fat suspension or paste nutrition, can connect the development report or the product of throwing something and feeding to the oral instant sweet taste soft capsule of newborn piglet greater than 10mm, core material.
Summary of the invention
The purpose of this invention is to provide a kind of soft capsule nutritional supplement that is applicable to newborn piglet and preparation method thereof, the present invention serves as to fill core with glue as glue shell, emulsified fat suspension or paste, can directly throw something and feed, and in the oral cavity, dissolve rapidly, taste is fresh and sweet, and to be convenient to sucking pig young edible, can avoid injecting or gavaging the harmful effect that brings to the sucking pig son.
Be applicable to the soft capsule nutritional supplement of newborn piglet, it is characterized in that: form by glue shell and filling core:
Described glue shell is made by the following weight proportion raw material:
Gelatin double centner, glycerine or concentration 70%(G/G) 12～50 kilograms in 10～30 kilograms of 10～30 kilograms of 60～130 kilograms of sorbierites, α-converted starches, starch, water, saccharin sodium 0.3-0.5 kilogram.
The preferred weight proportioning of described glue husk as raw material is:
Gelatin double centner, glycerine or concentration 70%(G/G) 42 kilograms in 22 kilograms of 20 kilograms of 120 kilograms of sorbierites, α-converted starches, starch, water, 0.3 kilogram of saccharin sodium.
The constituent of described filling core and weight proportion are:
Vitamin premix 0.5-1.5 kilogram, trace element premix agent 0.1-10 kilogram, complex enzyme 0.1-2.5 kilogram, probio 0.1-2.5 kilogram, active peptide 0.1-10 kilogram, acidulant 0.1-10 kilogram, glutamine 0.1-10 kilogram, arginine 0.1-5 kilogram, immunopotentiator 0.1-25 kilogram.
Described vitamin premix is mixed by at least two kinds of compositions of following weight proportion: retinyl acetate 0-5 kilogram, cholecalciferol 0-2 kilogram, vitamin E 0-20 kilogram, vitamin B1 0-1 kilogram, vitamin B2 0-2 kilogram, vitamin B6 0-1 kilogram, cobalamin 0-1.5 kilogram, niacinamide 0-8 kilogram, calcium pantothenate 0-4 kilogram, folic acid 0-0.5 kilogram, biotin 0-1.5 kilogram, prokeyvit 0-4 kilogram.
Described trace element premix agent is mixed by following components by weight ratio: ferrous glycine 0.01-10 kilogram, cupric glycinate 0.01-10 kilogram, glycine zine 0.01-10 kilogram, yeast manganese 0.01-10 kilogram, Potassiumiodate 0.01-10 kilogram, yeast selenium 0.01-5 kilogram, cobalt chloride 0.01-10 kilogram, chromium picolinate 0-3 kilogram.
Described complex enzyme is mixed by at least two kinds of enzymes of following active component: phytase 0-10000U/ gram, zytase 0-20000U/ gram, 1,4 beta-glucanase 0-20000U/ gram, pectase 0-5000U/ gram, mannase 0-5000U/ gram, cellulase 0-2000U/ gram, acid protease 0-5000U/ gram, neutral proteinase 0-2000U/ gram.
Described probio is selected from Bacillus acidi lactici or bacillus, and the total bacteria count of this probio is a 100-3000000000/gram.
Described acidulant is mixed by at least two kinds of compositions of following weight proportion: edible phosphoric acid 0-2 kilogram, fumaric acid 0-0.5 kilogram, lactic acid 0-2 kilogram, citric acid 0-1 kilogram, malic acid 0-0.5 kilogram.
Described immunopotentiator is mixed by at least two kinds of compositions of following weight proportion: origanum oil 0-0.7 kilogram, FOS 0-10 kilogram, manna oligosacchride 0-15 kilogram.
The described preparation method who is applicable to the soft capsule nutritional supplement of newborn piglet, undertaken by following processing step:
A, add pure water in for the glue bucket, add the sorbierite liquid of glycerine or 70% again, after stirring at the encapsulated glue of temperature control, be heated to 65-75 ℃,, keep temperature to continue to stir after 5-10 minute until fusion, add gelatin, α-converted starch, starch, saccharin sodium, continue stirring and dissolving after 75-120 minute, stop to stir, take out a barrel interior air, until vacuum≤-0.08 MPa, after taking off most bubble, obtain glue, maintain the temperature at 60 ℃;
B, each constituent that will fill heartwood are crushed to the 100-200 order and are placed on and join in the oil tank, behind the ratio adding emulsified fat of 0.1-1:1, stir then, stir after 20-30 minute, take out a jar interior air, be less than or equal to-0.05 MPa until vacuum, after taking off most bubble, obtain suspension content or paste content;
C, the glue of steps A gained and the suspension content or the paste content of step B gained are placed the soft capsule pellet press respectively, be pressed into soft capsule, wherein glue box temperature is 58-65 ℃, and the sprinkler body temperature is 37-47 ℃, humidity 35%-45%;
D, the soft capsule that step C is made place the typing rotating cage to finalize the design, setting temperature is that 22-25 ℃, humidity are 35%-45%, time is 6-8 hour, in pouring formula soft capsule washing machine, wash the ball degreasing rolling cage then with benzinum, remove liquid paraffin, the grease on surface, placing temperature at last is that 28-31 ℃, the drying room of humidity 25%-35% carry out drying, dry 4-8 hour, goes out ball when the capsule water content reaches 12-14%;
Describedly wash the ball degreasing and under temperature is 25-28 ℃, the condition of humidity 35%-45%, carry out;
The resulting dried capsule of E, selected step D, remove underproof capsule after, promptly obtain the soft capsule finished product;
The color of described soft capsule finished product is light yellow or golden yellow, is shaped as ellipse, garden shape, clavate or prismatic, and particle diameter is at the 10-20 millimeter, and length is the 20-30 millimeter, and every capsules contains content 0.5 gram or 1 gram.
The content of each composition that described soft capsule nutritional supplement finished product is contained is:
Vitamin A 0.5-50000 KIU/ kilogram, vitamin D 1-15000 KIU/ kilogram, vitamin E 1-5000 mg/kg, vitamin B1 0.5-2500 mg/kg, vitamin B2 0.5-2500 mg/kg, vitamin B6 0.5-2500 mg/kg, cobalamin 0.5-2500 mg/kg, niacinamide 0.5-2500 mg/kg, pantothenic acid 0.5-2500 mg/kg, folic acid 0.5-2500 mg/kg, biotin 0.5-2500 mg/kg, glutamine 100-50000 mg/kg, arginine 10-10000 mg/kg, iron 100-80000 mg/kg, copper 100-20000 mg/kg, zinc 50-50000 mg/kg, manganese 50-30000 mg/kg, iodine 0.01-10000 mg/kg, selenium 0.01-1000 mg/kg, cobalt 0.01-1000 mg/kg, complex enzyme 1-300000 U/ gram, probio 100-5000000000/gram, feeding active peptide 100-50000 mg/kg, feeding organic acid 100-50000 mg/kg, immunopotentiator 100-50000 mg/kg.
The described using method of the soft capsule nutritional supplement of newborn piglet that is applicable to is:
1, directly dropped into the oral instant soft capsule in the sucking pig oral cavity in 1-5 days sucking pig birth back, and every day 1 time, promptly 2 of 1 gram dosage or 0.5 gram dosage are 4;
2, the sucking pig birth after 5 days mixes in piglet feed the oral instant soft capsule for its free choice feeding.
Useful technique effect of the present invention shows:
1, the present invention adopts gelatin, glycerine, α-converted starch, saccharin sodium etc. to be made into the glue shell of capsule, with raw materials such as feeding vitamin, trace element, enzyme, probio, active peptide, organic acids as filling core, its preparation process and using method are simple, and can fully replenish the required nutrition of breast piglet in 1-5 days ages.
2, each raw material of the present invention matches and preparation process and control parameter, interacts, and constitutes a complete technical scheme.
3, the present invention can be in newborn piglet oral cavity dissolving fast, and discharge its nutrient, reach the effect of fast Absorption, and can alleviate or stop the intramuscular injection extra-nutrition and the oral cavity gavages the caused stress reaction that supplements the nutrients.
The specific embodiment
Embodiment 1
A kind of soft capsule nutritional supplement that is applicable to newborn piglet is characterized in that: be made up of glue shell and filling core:
Described glue shell is made by the following weight proportion raw material:
Gelatin double centner, 120 kilograms of glycerine, 20 kilograms of α-converted starches, 22 kilograms of starch, 42 kilograms in water, 0.3 kilogram of saccharin sodium.
The constituent of described filling core and weight proportion are:
11 kilograms of 1.0 kilograms of vitamin premix, 4.0 kilograms of trace element premix agent, 2.0 kilograms of complex enzymes, 1.5 kilograms of probios, 4.0 kilograms of active peptides, 3.5 kilograms of acidulants, 6.5 kilograms of glutamine, arginase 12 .5 kilogram, immunopotentiator.
Described vitamin premix is mixed by following components by weight ratio: 1 kilogram of retinyl acetate, 0.3 kilogram of cholecalciferol, 8 kilograms of vitamin Es, vitaminB10 .1 kilogram, 0.1 kilogram of vitamin B2,0.35 kilogram of vitamin B6,0.4 kilogram of cobalamin, 3 kilograms of niacinamide, 1.4 kilograms of calcium pantothenates, 0.09 kilogram in folic acid, 0.5 kilogram of biotin, 1 kilogram of prokeyvit.
Described trace element premix agent is mixed by following components by weight ratio: 4.5 kilograms of ferrous glycines, 2.5 kilograms of cupric glycinates, 3.7 kilograms of glycine zines, 4 kilograms in yeast manganese, 3.4 kilograms of Potassiumiodates, 1.5 kilograms of yeast seleniums, 0.65 kilogram of cobalt chloride, 2 kilograms of chromium picolinates.
Described complex enzyme is mixed by the enzyme of following active component: phytase 10000U/ gram, zytase 10000U/ gram, 1,4 beta-glucanase 20000U/ gram, pectase 2000U/ gram, cellulase 800U/ gram, acid protease 3000U/ gram, neutral proteinase 1000U/ gram.
Described probio is selected from Bacillus acidi lactici, and its total bacteria count is 500000000 a/gram.
The composition that described acidulant is joined by following weight mixes: 2 kilograms of edible phosphoric acids, 0.3 kilogram of fumaric acid, 1 kilogram of lactic acid, 0.5 kilogram of malic acid.
Described immunopotentiator is mixed by following components by weight ratio: 0.5 kilogram of origanum oil, 5 kilograms of FOSs, 10 kilograms of manna oligosacchrides.
The described preparation method who is applicable to the soft capsule nutritional supplement of newborn piglet, undertaken by following processing step:
A, add pure water in for the glue bucket, add glycerine again, after stirring at the encapsulated glue of temperature control, be heated to 65 ℃,, keep temperature to continue to stir after 10 minutes until fusion, add gelatin, α-converted starch, starch, saccharin sodium, continue stirring and dissolving after 100 minutes, stop to stir, take out a barrel interior air, until vacuum is-0.05 MPa, after taking off most bubble, obtain glue, maintain the temperature at 60 ℃;
B, each constituent that will fill heartwood are crushed to 160 orders and are placed on and join in the oil tank, behind the ratio adding emulsified fat of 0.5:1, stir then, stir after 25 minutes, take out a jar interior air, be less than or equal to-0.05 MPa until vacuum, after taking off most bubble, obtain the paste content;
C, the glue of steps A gained and the paste content of step B gained are placed the soft capsule pellet press respectively, be pressed into soft capsule, wherein glue box temperature is 60 ℃, and the sprinkler body temperature is 38 ℃, and humidity is 36%;
D, the soft capsule that step C is made place the typing rotating cage to finalize the design, setting temperature is that 22-25 ℃, humidity are 35%, 6 hours time, in pouring formula soft capsule washing machine, wash the ball degreasing rolling cage then with benzinum, remove liquid paraffin, the grease on surface, placing temperature at last is that 29 ℃, the drying room of humidity 26% carry out drying, 4 hours drying times, goes out ball when the capsule water content reaches 14%;
Describedly wash the ball degreasing and under the condition of 25 ℃ of temperature, humidity 35%, carry out;
The resulting dried capsule of E, selected step D, remove underproof capsule after, promptly obtain the soft capsule finished product;
The color of described soft capsule finished product is golden yellow, is shaped as ellipse, and particle diameter is at 12 millimeters, and length is the 20-30 millimeter, and every capsules contains content 0.5 gram.
The content of each composition that described soft capsule nutritional supplement finished product is contained is:
Vitamin A 200000 KIU/kg, vitamin D 30000 KIU/ kilograms, vitamin E 800 mg/kg, vitamin B1 20 mg/kg, vitamin B2 120 mg/kg, vitamin B6 80 mg/kg, cobalamin 1.6 mg/kg, niacinamide 800 mg/kg, pantothenic acid 200 mg/kg, folic acid 60 mg/kg, glutamine 17560 mg/kg, arginine 6760 mg/kg, iron 2400 mg/kg, copper 1500 mg/kg, zinc 2400 mg/kg, manganese 600 mg/kg, iodine 30 mg/kg, selenium 9 mg/kg, cobalt 24 mg/kg, chromium 6 mg/kg, complex enzyme 100000 KIU/ gram, 1000000/gram of probio, active peptide 8830 mg/kg, acidulant 17670 mg/kg, immunopotentiator 31800 mg/kg.
The described using method of the soft capsule nutritional supplement of newborn piglet that is applicable to is:
1, sucking pig birth back was directly dropped into the oral instant soft capsule in the sucking pig oral cavity every day 1 time, each 4 in 1-5 days;
2, the sucking pig birth after 5 days mixes in piglet feed the oral instant soft capsule for its free choice feeding.
Embodiment 2
A kind of soft capsule nutritional supplement that is applicable to newborn piglet is characterized in that: be made up of glue shell and filling core:
Described glue shell is made by the following weight proportion raw material:
Gelatin double centner, concentration 70%(G/G) 15 kilograms in 12 kilograms of 15 kilograms of 70 kilograms of sorbierites, α-converted starches, starch, water, 0.3 kilogram of saccharin sodium.
The constituent of described filling core and weight proportion are:
1.5 kilograms of vitamin premix, 10 kilograms of trace element premix agent, 1.0 kilograms of complex enzymes, 2.5 kilograms of probios, 10 kilograms of active peptides, 8.0 kilograms of acidulants, 1.0 kilograms of glutamine, 5 kilograms of arginine, 20 kilograms of immunopotentiators.
Described vitamin premix is mixed by following components by weight ratio: 1.5 kilograms of retinyl acetates, 0.4 kilogram of cholecalciferol, 10 kilograms of vitamin Es, vitaminB10 .12 kilogram, 0.8 kilogram of vitamin B2,0.4 kilogram of vitamin B6,0.5 kilogram of cobalamin, 3 kilograms of niacinamide, 1.5 kilograms of calcium pantothenates, 0.1 kilogram in folic acid, 0.5 kilogram of biotin, 1.5 kilograms of prokeyvits.
Described trace element premix agent is mixed by following components by weight ratio: 5.5 kilograms of ferrous glycines, 1.5 kilograms of cupric glycinates, 3.7 kilograms of glycine zines, 6.2 kilograms in yeast manganese, 0.2 kilogram of Potassiumiodate, 1.75 kilograms of yeast seleniums, 0.57 kilogram of cobalt chloride, 2 kilograms of chromium picolinates.
Described complex enzyme is mixed by the enzyme of following active component: zytase 20000U/ gram, 1,4 beta-glucanase 8000U/ gram, pectase 5000U/ gram, cellulase 2000U/ gram, neutral proteinase 2000U/ gram.
Described probio is selected from bacillus, and its total bacteria count is 100 a/gram.
The composition that described acidulant is joined by following weight mixes: 0.6 kilogram of edible phosphoric acid, 0.5 kilogram of fumaric acid, 2.0 kilograms of lactic acid, 0.8 kilogram of citric acid, 0.5 kilogram of malic acid.
Described immunopotentiator is mixed by following components by weight ratio: 0.7 kilogram of origanum oil, 3.0 kilograms of FOSs, 5.3 kilograms of manna oligosacchrides.
The described preparation method who is applicable to the soft capsule nutritional supplement of newborn piglet, undertaken by following processing step:
A, add pure water in for the glue bucket, add 70% sorbierite again, after stirring at the encapsulated glue of temperature control, be heated to 75 ℃,, keep temperature to continue to stir after 10 minutes until fusion, add gelatin, α-converted starch, starch, saccharin sodium, continue stirring and dissolving after 110 minutes, stop to stir, take out a barrel interior air, until vacuum is-0.08 MPa, after taking off most bubble, obtain glue, maintain the temperature at 60 ℃;
B, each constituent that will fill heartwood are crushed to 140 orders and are placed on and join in the oil tank, behind the ratio adding emulsified fat of 1:1, stir then, stir after 20 minutes, take out a jar interior air, be less than or equal to-0.05 MPa until vacuum, after taking off most bubble, obtain the suspension content;
C, the glue of steps A gained and the suspension content of step B gained are placed the soft capsule pellet press respectively, be pressed into soft capsule, wherein glue box temperature is 62 ℃, and the sprinkler body temperature is 42 ℃, humidity 40%;
D, the soft capsule that step C is made place the typing rotating cage to finalize the design, setting temperature is that 25 ℃, humidity are 40%, 7 hours time, in pouring formula soft capsule washing machine, wash the ball degreasing rolling cage then with benzinum, remove liquid paraffin, the grease on surface, placing temperature at last is that 30 ℃, the drying room of humidity 30% carry out drying, 6 hours drying times, goes out ball when the capsule water content reaches 12%;
Describedly wash the ball degreasing and under the condition of 26 ℃ of temperature, humidity 40%, carry out;
The resulting dried capsule of E, selected step D, remove underproof capsule after, promptly obtain the soft capsule finished product;
The color of described soft capsule finished product is golden yellow, is shaped as garden shape, and particle diameter is at 20 millimeters, and every capsules contains content 1 gram.
The content of each composition that described soft capsule nutritional supplement finished product is contained is:
Vitamin A 1770000KIU/kg, vitamin D 236000KIU/ kilogram, vitamin E 5900 mg/kg, vitamin B1 177 mg/kg, vitamin B2 944 mg/kg, vitamin B6 590 mg/kg, cobalamin 7.08 mg/kg, niacinamide 3540 mg/kg, pantothenic acid 1770 mg/kg, folic acid 236 mg/kg, glutamine 15900 mg/kg, arginine 5300 mg/kg, iron 3500 mg/kg, copper 1050 mg/kg, zinc 3500 mg/kg, manganese 1050 mg/kg, iodine 21 mg/kg, selenium 12.25 mg/kg, cobalt 24.5 mg/kg, chromium 7 mg/kg, complex enzyme 100000 KIU/ gram, 1000000/gram of probio, active peptide 8830 mg/kg, acidulant 17670 mg/kg, immunopotentiator 31800 mg/kg.
The described using method of the soft capsule nutritional supplement of newborn piglet that is applicable to is:
1, sucking pig birth back was directly dropped into the oral instant soft capsule in the sucking pig oral cavity every day 1 time, each 2 in 1-5 days;
2, the sucking pig birth after 5 days mixes in piglet feed the oral instant soft capsule for its free choice feeding.
Embodiment 3
A kind of soft capsule nutritional supplement that is applicable to newborn piglet is characterized in that: be made up of glue shell and filling core:
Described glue shell is made by the following weight proportion raw material:
Gelatin double centner, 120 kilograms of glycerine, 30 kilograms of α-converted starches, 25 kilograms of starch, 35 kilograms in water, 0.5 kilogram of saccharin sodium.
The constituent of described filling core and weight proportion are:
1.5 kilograms of vitamin premix, 5 kilograms of trace element premix agent, 2.5 kilograms of complex enzymes, 2.0 kilograms of probios, 5.0 kilograms of active peptides, 5.5 kilograms of acidulants, 6.5 kilograms of glutamine, 3.0 kilograms of arginine, 20.0 kilograms of immunopotentiators.
Described vitamin premix is mixed by following components by weight ratio: 1.8 kilograms of retinyl acetates, 0.45 kilogram of cholecalciferol, 2 kilograms of vitamin e1s, vitaminB10 .1 kilogram, 0.7 kilogram of vitamin B2,0.4 kilogram of vitamin B6,0.4 kilogram of cobalamin, 3.1 kilograms of niacinamide, 1.5 kilograms of calcium pantothenates, 0.11 kilogram in folic acid, 0.5 kilogram of biotin, 2 kilograms of prokeyvits.
Described trace element premix agent is mixed by following components by weight ratio: 6.6 kilograms of ferrous glycines, 0.8 kilogram of cupric glycinate, 5.6 kilograms of glycine zines, 4.1 kilograms in yeast manganese, 0.35 kilogram of Potassiumiodate, 1.5 kilograms of yeast seleniums, 0.65 kilogram of cobalt chloride, 2 kilograms of chromium picolinates.
Described complex enzyme is mixed by the enzyme of following active component: pectase 2000U/ gram, mannase 3000U/ gram.
Described probiotic is selected from the mixture of Bacillus acidi lactici and bacillus, and the total bacteria count of this probio is 3000000000 a/gram.
The composition that described acidulant is joined by following weight mixes: 1.5 kilograms of edible phosphoric acids, 0.5 kilogram of fumaric acid, 2 kilograms of lactic acid, 1 kilogram of citric acid, 0.5 kilogram of malic acid.
Described immunopotentiator is mixed by following components by weight ratio: 0.7 kilogram of origanum oil, 10 kilograms of FOSs, 9.3 kilograms of manna oligosacchrides.
The described preparation method who is applicable to the soft capsule nutritional supplement of newborn piglet, undertaken by following processing step:
A, add pure water in for the glue bucket, add glycerine again, after stirring at the encapsulated glue of temperature control, be heated to 75 ℃,, keep temperature to continue to stir after 10 minutes until fusion, add gelatin, α-converted starch, starch, saccharin sodium, continue stirring and dissolving after 120 minutes, stop to stir, take out a barrel interior air, until vacuum is-0.08 MPa, after taking off most bubble, obtain glue, maintain the temperature at 60 ℃;
B, each constituent that will fill heartwood are crushed to 120 orders and are placed on and join in the oil tank, behind the ratio adding emulsified fat of 0.1:1, stir then, stir after 30 minutes, take out a jar interior air, be less than or equal to-0.05 MPa until vacuum, after taking off most bubble, obtain the paste content;
C, the glue of steps A gained and the paste content of step B gained are placed the soft capsule pellet press respectively, be pressed into soft capsule, wherein glue box temperature is 65 ℃, and the sprinkler body temperature is 47 ℃, humidity 45%;
D, the soft capsule that step C is made place the typing rotating cage to finalize the design, setting temperature is that 25 ℃, humidity are 45%, 7 hours time, in pouring formula soft capsule washing machine, wash between the ball degreasing rolling cage then with benzinum, remove liquid paraffin, the grease on surface, placing temperature at last is that 30 ℃, the drying room of humidity 35% carry out drying, dry 6 hours, goes out ball when the capsule water content reaches 13%;
Describedly wash the ball degreasing and under the condition of 28 ℃ of temperature, humidity 40%, carry out;
The resulting dried capsule of E, selected step D, remove underproof capsule after, promptly obtain the soft capsule finished product;
The color of described soft capsule finished product is golden yellow, is shaped as clavate, and particle diameter is at 20 millimeters, and length is 30 millimeters, and every capsules contains content 1 gram.
The content of each composition that described soft capsule nutritional supplement finished product is contained is:
Vitamin A 1800000 KIU/kg, vitamin D 220000 KIU/ kilograms, vitamin E 6000 mg/kg, vitamin B1 150 mg/kg, vitamin B2 800 mg/kg, vitamin B6 500 mg/kg, cobalamin 10 mg/kg, niacinamide 5000 mg/kg, pantothenic acid 2000 mg/kg, folic acid 1000 mg/kg, glutamine 12750 mg/kg, arginine 5880 mg/kg, iron content 3600 mg/kg, copper content 450 mg/kg, zinc content 3600 mg/kg, manganese content 600 mg/kg, content of iodine 30 mg/kg, Se content 9 mg/kg, cobalt content 24 mg/kg, chromium content 6 mg/kg, complex enzyme 500000 KIU/ gram, 5000000/gram of probio, active peptide 9800 mg/kg, acidulant 10780 mg/kg, immunopotentiator 39220 mg/kg.
The described using method of the soft capsule nutritional supplement of newborn piglet that is applicable to is:
1, sucking pig birth back was directly dropped into the oral instant soft capsule in the sucking pig oral cavity every day 1 time, each 2 in 1-5 days;
2, the sucking pig birth after 5 days mixes in piglet feed the oral instant soft capsule for its free choice feeding.
Claims (10)
1. be applicable to the soft capsule nutritional supplement of newborn piglet, it is characterized in that: form by glue shell and filling core:
Described glue shell is made by the following weight proportion raw material: gelatin double centner, glycerine or mass percent concentration are 70% 12～50 kilograms in 10～30 kilograms of 10～30 kilograms of 60～130 kilograms of sorbierites, α-converted starches, starch, water, saccharin sodium 0.3-0.5 kilogram;
The constituent of described filling core and weight proportion are: vitamin premix 0.5-1.5 kilogram, trace element premix agent 0.1-10 kilogram, complex enzyme 0.1-2.5 kilogram, probio 0.1-2.5 kilogram, active peptide 0.1-10 kilogram, acidulant 0.1-10 kilogram, glutamine 0.1-10 kilogram, arginine 0.1-5 kilogram, immunopotentiator 0.1-25 kilogram.
2. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1, it is characterized in that: the weight proportion of described glue husk as raw material is: gelatin double centner, glycerine or mass percent concentration are 70% 42 kilograms in 22 kilograms of 20 kilograms of 120 kilograms of sorbierites, α-converted starches, starch, water, 0.3 kilogram of saccharin sodium.
3. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1 is characterized in that: described vitamin premix is mixed by at least two kinds of compositions of following weight proportion: retinyl acetate 0-5 kilogram, vitamin D
30-2 kilogram, vitamin E 0-20 kilogram, Cobastab
10-1 kilogram, Cobastab
20-2 kilogram, Cobastab
60-1 kilogram, Cobastab
120-1.5 kilogram, niacinamide 0-8 kilogram, calcium pantothenate 0-4 kilogram, folic acid 0-0.5 kilogram, biotin 0-1.5 kilogram, vitamin K
3The 0-4 kilogram.
4. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1 is characterized in that: described trace element premix agent is mixed by following components by weight ratio: ferrous glycine 0.01-10 kilogram, cupric glycinate 0.01-10 kilogram, glycine zine 0.01-10 kilogram, yeast manganese 0.01-10 kilogram, Potassiumiodate 0.01-10 kilogram, yeast selenium 0.01-5 kilogram, cobalt chloride 0.01-10 kilogram, chromium picolinate 0-3 kilogram.
5. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1 is characterized in that: described complex enzyme is mixed by at least two kinds of enzymes of following active component: phytase 0-10000U/ gram, zytase 0-20000U/ gram, 1,4 beta-glucanase 0-20000U/ gram, pectase 0-5000U/ gram, mannase 0-5000U/ gram, cellulase 0-2000U/ gram, acid protease 0-5000U/ gram, neutral proteinase 0-2000U/ gram.
6. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1, it is characterized in that: described probio is selected from Bacillus acidi lactici or bacillus, and the total bacteria count of this probio is a 100-3000000000/gram.
7. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1 is characterized in that: described acidulant is mixed by at least two kinds of compositions of following weight proportion: edible phosphoric acid 0-2 kilogram, fumaric acid 0-0.5 kilogram, lactic acid 0-2 kilogram, citric acid 0-1 kilogram, malic acid 0-0.5 kilogram.
8. the soft capsule nutritional supplement that is applicable to newborn piglet according to claim 1 is characterized in that: described immunopotentiator is mixed by at least two kinds of compositions of following weight proportion: origanum oil 0-0.7 kilogram, FOS 0-10 kilogram, manna oligosacchride 0-15 kilogram.
9. the preparation method who is applicable to the soft capsule nutritional supplement of newborn piglet according to claim 1 is characterized in that: undertaken by following processing step:
A, add pure water in for the glue bucket, add glycerine or mass percent again and be 70% sorbierite liquid, after stirring at the encapsulated glue of temperature control, be heated to 65-75 ℃,, keep temperature to continue to stir after 5-10 minute until fusion, add gelatin, α-converted starch, starch, saccharin sodium, continue stirring and dissolving after 75-120 minute, stop to stir, take out a barrel interior air, until vacuum≤-0.08 MPa, after taking off most bubble, obtain glue, maintain the temperature at 60 ℃;
B, each constituent that will fill heartwood are crushed to the 100-200 order and are placed on and join in the oil tank, after adding emulsified fat, 0.1-1:1 stirs then, stir after 20-30 minute, take out a jar interior air, be less than or equal to-0.05 MPa until vacuum, after taking off most bubble, obtain suspension content or paste content;
C, the glue of steps A gained and the suspension content or the paste content of step B gained are placed the soft capsule pellet press respectively, be pressed into soft capsule, wherein glue box temperature is 58-65 ℃, and the sprinkler body temperature is 37-47 ℃, humidity 35%-45%;
D, the soft capsule that step C is made place the typing rotating cage to finalize the design, setting temperature is that 22-25 ℃, humidity are 35%-45%, time 6-8 hour, in pouring formula soft capsule washing machine, wash the ball degreasing rolling cage then with benzinum, remove liquid paraffin, the grease on surface, placing temperature at last is that 28-31 ℃, the drying room of humidity 25%-35% carry out drying, dry 4-8 hour, goes out ball when the capsule water content reaches 12-14%;
Describedly wash the ball degreasing and under temperature 25-28 ℃, the condition of humidity 35%-45%, carry out;
The resulting dried capsule of E, selected step D, remove underproof capsule after, promptly obtain the soft capsule finished product.
10. the preparation method who is applicable to the soft capsule nutritional supplement of newborn piglet according to claim 9 is characterized in that: the content of each composition that described soft capsule finished product is contained is:
Vitamin A 0.5-50000 KIU/ kilogram, vitamin D 1-15000 KIU/ kilogram, vitamin E 1-5000 mg/kg, Cobastab
10.5-2500 mg/kg, Cobastab
20.5-2500 mg/kg, Cobastab
60.5-2500 mg/kg, Cobastab
120.5-2500 mg/kg, niacinamide 0.5-2500 mg/kg, pantothenic acid 0.5-2500 mg/kg, folic acid 0.5-2500 mg/kg, biotin 0.5-2500 mg/kg, glutamine 100-50000 mg/kg, arginine 10-10000 mg/kg, iron 100-80000 mg/kg, copper 100-20000 mg/kg, zinc 50-50000 mg/kg, manganese 50-30000 mg/kg, iodine 0.01-10000 mg/kg, selenium 0.01-1000 mg/kg, cobalt 0.01-1000 mg/kg, complex enzyme 1-300000 U/ gram, probio 100-5000000000/gram, feeding active peptide 100-50000 mg/kg, feeding organic acid 100-50000 mg/kg, immunopotentiator 100-50000 mg/kg.
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| CN2010106083669A CN102125179B (en) | 2010-12-28 | 2010-12-28 | Soft capsule nutritional supplement applicable to piglets and preparation method thereof |
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| CN2010106083669A CN102125179B (en) | 2010-12-28 | 2010-12-28 | Soft capsule nutritional supplement applicable to piglets and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103125750A (en) * | 2011-11-21 | 2013-06-05 | 南通中科睿智科技服务有限公司 | Nutrition additive of young bird livestock and poultry feed |
| CN103181479A (en) * | 2011-12-27 | 2013-07-03 | 北京资源亚太饲料科技有限公司 | Microecological preparation special for newborn piglets and its preparation method |
| CN103704473A (en) * | 2013-12-13 | 2014-04-09 | 浙江凯迈生物科技有限公司 | Lean-type piglet feed |
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| CN103125750A (en) * | 2011-11-21 | 2013-06-05 | 南通中科睿智科技服务有限公司 | Nutrition additive of young bird livestock and poultry feed |
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| CN104905062A (en) * | 2015-06-11 | 2015-09-16 | 湖南傲农生物科技有限公司 | Premix capable of increasing short chain fatty acid of colon of weaned piglets |
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| CN107647130A (en) * | 2017-08-25 | 2018-02-02 | 湖南傲农生物科技有限公司 | A kind of feed for promoting piggy skeleton development and preparation method thereof |
| CN108157609A (en) * | 2018-03-15 | 2018-06-15 | 淮南市宋王优质粮食种植农民专业合作社 | A kind of feed addictive of snakeheaded fish raising treatment snakeheaded fish Ascites Disease |
| CN108208471A (en) * | 2018-03-15 | 2018-06-29 | 淮南市宋王优质粮食种植农民专业合作社 | A kind of snakeheaded fish raising feed addictive that snakeheaded fish is promoted to digest and assimilate |
| CN108244411A (en) * | 2018-03-15 | 2018-07-06 | 淮南市宋王优质粮食种植农民专业合作社 | A kind of snakeheaded fish raising treatment snakeheaded fish bark rot feed and preparation method thereof |
| WO2020109492A1 (en) * | 2018-11-28 | 2020-06-04 | Targedys | Mineral elements comprising hafnia alvei compositions |
| CN109645242A (en) * | 2019-01-10 | 2019-04-19 | 广东驱动力生物科技股份有限公司 | A kind of piglet pearl shape blood enriching capsule and preparation method thereof |
| CN114886039A (en) * | 2022-04-19 | 2022-08-12 | 江苏派莘生物科技有限公司 | Compound premix for improving plumpness of poultry feather and skeletal development and preparation method thereof |
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