CN102119879B - Antiallergic gel nose-protecting medical supply and making method thereof - Google Patents
Antiallergic gel nose-protecting medical supply and making method thereof Download PDFInfo
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- CN102119879B CN102119879B CN 201110031783 CN201110031783A CN102119879B CN 102119879 B CN102119879 B CN 102119879B CN 201110031783 CN201110031783 CN 201110031783 CN 201110031783 A CN201110031783 A CN 201110031783A CN 102119879 B CN102119879 B CN 102119879B
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Abstract
The invention relates to an antiallergic gel nose-protecting medical supply and a making method thereof. The nose-protecting medical supply consists of a nose-shading sheet, antiallergic gel and a natural antipathogenic microorganism biomaterial. The nose-shading sheet consists of a film and a filtering sheet. One surface of the film is sticky. The left side and the right side of the film are provided with a left wing part and a right wing part. One side of the film is provided with a plurality of incision lines. A protruding part is arranged in the center of the film. The filtering sheet is arranged at the position of the protruding part in the center of the film and is tilted upwardly. The film surface of the filtering sheet is smeared with antiallergic gel, while the nose surface of the filtering sheet is smeared with natural antipathogenic microorganism biomaterial. The antiallergic gel nose-protecting medical supply is disposable and decomposable and mist on glasses of a user is prevented. Medical biomaterial in the invention has no toxic or side effect, so the antiallergic gel nose-protecting medical supply is safe for children, pregnant women and drivers and is convenient to use. The antiallergic gel nose-protecting medical supply is made by a simple process, is appropriate in cost, and is environmentally-friendly during production.
Description
Technical field
The present invention relates to a kind of antiallergic gel nose protection medical supplies and preparation method thereof.
Background technology
The sickness rate of China's allergic rhinitis reaches 20%--40%, this means the Allergic Rhinitis of 400,000,000 left and right; Wherein have an appointment the patient of 30% left and right again with bronchial asthma.Along with large commercial production and expanding economy, air quality is also to worsen year by year.World Health Organization (WHO) has classified allergic rhinitis as serious global health problem.
Allergic rhinitis refers to that the nasal mucosa reactivity increases and the class nose diseases that causes, when Yi Fayu spring and autumn and exchange in season.Nasal obstruction, sneeze, rhinocnesmus, watery nasal discharge are typical four large symptoms.The patient will thoroughly treat this class disease, need carry out comprehensive therapeutic plan: comprise avoid that contact allergy is former, the therapy of Drug therapy, desensitization treatment and daily health caring " quaternity ".
In this four meas ures, Drug therapy is the most expensive, and side effect is larger method also.The prerequisite of desensitization therapy is will be for individuality finds anaphylactogen accurately, and this process is not only time-consuming but also bother also expensive.Daily health caring can not to because of, the ordinary people can not adhere to.Therefore, avoiding contact allergy former should be most economical effective mode.
But in actual life, the patient often is difficult to accomplish, because the people can not stay in clean room all one's life, also can not one day 24 hours or wear masks for a long time, and this is both unrealistic also without much effects.So, avoid former this measure of contact allergy, the way that people there is no.
Though have the antiallergic gel to be put on the measure that the nostril periphery is used as the Polyglucan rhinitis at present, it can not effectively stop the sensitizing factor in breathe air in fact, also the effect of killing pathogenic microorganism in air can not be arranged.
Therefore, be badly in need of the real active adsorption anaphylactogen of a kind of energy on current market and kill the nose protection medical supplies of pathogenic microorganism in air, satisfy and avoid this effective demand of contacting with anaphylactogen.
Summary of the invention
The objective of the invention is in order to overcome defective and the problem of above-mentioned prior art existence; a kind of antiallergic gel nose protection medical supplies and preparation method thereof are provided; these antiallergic gel nose protection medical supplies can be used for Allergic Rhinitis to be avoided contacting with anaphylactogen, thereby plays the purpose of prevent disease outbreak.It can not only play airfiltering effect, and the adsorbable airborne dirt demodicid mite of the antiallergic gel on filter, pollen, dust, animal hair etc., thereby effectively blocks inhalant allergens to the sensitization of whole respiratory tract; In addition, the natural resisting pathogenic microbes biomaterial on filter can also have killing action to the pathogenic microorganism in air amount.This antiallergic gel nose protection medical supplies can be complied with according to the nose shape of various different sizes and post, and are discardable decomposition after disposable use, and the people with glasses can not produce fog.Bio-medical material composition in antiallergic gel nose protection medical supplies is without any side effects, and child, anemia of pregnant woman and driver also can use safely, and easy to use.Antiallergic gel nose protection medical supplies production technology is easy, and price is suitable, in production process to environment without any pollution.
A kind of antiallergic gel nose protection medical supplies form by hiding rhinarium, antiallergic gel and natural resisting pathogenic microbes biomaterial, and it is characterized in that: described screening rhinarium is comprised of pad pasting and filter; The one side of pad pasting has adhibit quality, the pad pasting left and right sides is designed with section of left wing and right wing part, pad pasting one side prepares a plurality of cut line, pad pasting central authorities are prepared with protuberance, filter is placed in pad pasting central authorities protuberance place, and filter is inclined upwardly, and the pad pasting face of filter is covered with the antiallergic gel, and the nostril surface of filter is covered with natural resisting pathogenic microbes biomaterial.Described pad pasting is that elasticity, gas permeable material flexible, that do not affect eupnea are made; The one side of pad pasting have can be compatible with human skin tissue adhibit quality, a plurality of cut line of pad pasting one side preparation be various nose shapes because of the use of stretcher strain, the protuberance of pad pasting central authorities is when filter is placed in pad pasting central authorities protuberance place, filter is inclined upwardly, the nostril opening part can be covered fully.
Described pad pasting for have elasticity, flexible, gas permeable material is made, described filter is that gas permeable material is made.During use, antiallergic gel nose protection medical supplies are attached at the nose lower end, and the left and right alar part of pad pasting that hides rhinarium is posted in place, wing of nose bottom, just cover in the nostril, both sides and locate and hide filter on the pad pasting of rhinarium.
Described antiallergic gel comprises following component, each component by weight percentage:
Natural plants cationic colloidal 0.1-1%
Simethicone 10-40%
Antiseptic 0.1-1%
Glycerol 0.5-5%
Propylene glycol 0.1-3%
Essence 0.01-0.1%
The purified water surplus.
Natural plants cationic colloidal in above-mentioned antiallergic gel is a kind of or wantonly two kinds of mixture in cation guar gum, cation locust bean gum, Cationic Fenugreek Gum, cationic sesbania gum, cation artemisia glue, cation Radix Astragali glue, and cation guar gum, cation locust bean gum, Cationic Fenugreek Gum, cationic sesbania gum, cation artemisia glue, cation Radix Astragali glue are all bought from market.
Antiseptic in above-mentioned antiallergic gel is: a kind of or wantonly two kinds of mixture in benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben.
Natural resisting pathogenic microbes biomaterial in antiallergic gel nose protection medical supplies is that mass concentration is the water-soluble chitosan solution of 0.1-5%; water-soluble chitosan is one or two or more kinds the mixture in carboxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan, N-trimethyl oxidation chitosan, and carboxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan, N-trimethyl oxidation chitosan are all bought from market.
Natural resisting pathogenic microbes biomaterial in antiallergic gel nose protection medical supplies is the nano-silver biological material, and diameter is the silver-colored simple substance nano-particle between 1-100nm, is commercially available.
The preparation method of antiallergic gel nose protection medical supplies of the present invention, carry out as follows:
A), by said ratio, natural plants cationic colloidal, simethicone, antiseptic, glycerol, propylene glycol, essence and purified water are mixed and make the antiallergic gel after stirring evenly;
B), the preparation mass concentration is the water-soluble chitosan solution of 0.1-5%;
C), select to have elasticity, gas permeable material flexible, that do not affect eupnea prepares pad pasting, a side is prepared with according to various nose shapes and a plurality of cut line of stretcher strain; Pad pasting central authorities are prepared with protuberance;
D), select gas permeable material to prepare filter, filter pad pasting face is covered with the antiallergic gel, prepares fine hole pattern at gel layer; Filter nostril side infiltrates dries after the water-soluble chitosan solution that mass concentration is 0.1-5% or nanometer silver is coated on filter nostril side;
E), filter is placed in pad pasting central authorities protuberance place, and filter is inclined upwardly, the nostril opening part can be covered fully; The section of left wing of pad pasting both sides and the one side of right wing part are smeared medical pressure-sensitive adhesive, carry out on the glue face and cover protective layer; Make antiallergic gel nose protection medical supplies.
Also comprise step f in above-mentioned preparation method), f), with e) after the antiallergic gel nose that the makes protection medical supplies packing in step, carry out the oxirane disinfection sterilization, get the manufactured goods of antiallergic gel nose protection medical supplies.
The adsorbable airborne dirt demodicid mite of antiallergic gel nose protection medical supplies of the present invention, pollen, dust, animal hair etc., thus the blocking-up inhalant allergens is to the sensitization of whole respiratory tract; And can killing action be arranged to the pathogenic microorganism in air amount, thus reduce or reduce pathogenic microorganism to whole respiratory tract, especially to the invasion and attack effect of upper respiratory tract.
Antiallergic gel in antiallergic gel nose protection medical supplies of the present invention, natural plants cationic colloidal wherein can effectively be blocked inhalant allergens to the effect of human body by the electrostatic adsorption in the physics; And the antiallergic gelling properties is stable, and is without hormone or pharmaceutical compositions, by body metabolism, not without any side effects.
Water-soluble chitosan biomaterial in antiallergic gel nose protection medical supplies of the present invention is a kind of natural polymer, extensively is present in the carapaces such as shrimp, Eriocheir sinensis, and be the product after the chitin deacetylate.Water-soluble chitosan contains free amine group, and reactivity is strong, and known have blood fat reducing, blood pressure lowering, blood sugar lowering, increase immunity, the antibiotic effect such as anticancer, and to the human body non-evident effect.With the increase of water-soluble chitosan concentration, the effect of its antibacterial action strengthens.The more important thing is, water-soluble chitosan has good broad-spectrum disease resistance cytotoxic activity, and many rhinovirus and Respirovirus are all had deactivation preferably, can also suppress the activity of SARS virus.Water-soluble chitosan makes virus be difficult to adhere to and penetrates in cell because having strong adsorption, affects the propagation that copies of virus; Can also activate reticuloendothelial system and cell immune system, strengthen Effects on local immunological functions, make the T lymphocyte discharge multiple lymphokine and participate in killing and wounding the cell that infects virus, and stop viral nucleic acid and protein to be combined into virion in host cell.Therefore the water-soluble chitosan biomaterial of filter nostril surface in antiallergic gel nose protection medical supplies, also play the effect of very important Polyglucan rhinitis outbreak.
The nano-silver biological material is except powerful bactericidal action, outside human body is had no side effect, it also has good antivirus action simultaneously, as parainfluenza virus, bird flu virus etc. is all had strong deactivation, may adsorb and fixation the mechanicalness of virus with nanometer silver, the Ag+ that nanometer silver discharges directly has destruction to virus, and can stop the cell entry host cell relevant.
Antiallergic gel nose protection medical supplies production technology is easy, and price is suitable, in production process to environment without any pollution.
Description of drawings
Fig. 1 is the structural representation that the present invention hides rhinarium.
The specific embodiment
Describe the present invention in detail below in conjunction with drawings and Examples.Should be understood that these embodiment only to be used for explanation the present invention and be not used in and limit the scope of the invention.
As shown in Figure 1, screening rhinarium of the present invention is comprised of pad pasting 1 and filter 2; The one side of pad pasting 1 has adhibit quality, and the pad pasting left and right sides is designed with section of left wing 3 and right wing part 4, and pad pasting one side prepares a plurality of cut line 5, and pad pasting central authorities are prepared with protuberance, and filter 2 is placed in the central protuberance of pad pasting 1 place, and filter is inclined upwardly.
One, preparation 100g antiallergic gel, 100g carboxymethyl chitosan sugar juice and corresponding antiallergic gel nose protection medical supplies
1. with the pure water of 0.1 gram cation guar gum, 10 gram simethicone, 0.1 gram methyl hydroxybenzoate, 0.5 gram glycerol, 0.1 gram propylene glycol, 0.01 gram essence and surplus, mixing stirs evenly, and is stand-by;
2. 0.1 gram carboxymethyl chitosan is dissolved in the pure water of 99.9 grams, makes 100 gram carboxymethyl chitosan sugar juices;
3. selection has elasticity, gas permeable material flexible, that do not affect eupnea prepares pad pasting, the one side of pad pasting has the adhibit quality compatible with tissue, and extend alar part in its left and right sides, also be prepared with according to various nose shapes and a plurality of cut line of stretcher strain at the pad pasting upside; Pad pasting central authorities are prepared with protuberance;
4. the gas permeable material of selecting not affect eupnea prepares filter; Filter pad pasting face is applied the antiallergic gel that makes with step 1; Simultaneously prepare fine hole pattern at gel layer;
5. the carboxymethyl chitosan sugar juice that again filter nostril side infiltration is made with step 2, then dry;
6. filter is placed in pad pasting central authorities protuberance place; The section of left wing of pad pasting both sides and the one side of right wing part are smeared medical pressure-sensitive adhesive, carry out on the glue face and cover protective layer, make antiallergic gel nose protection medical supplies;
7. with after this finished product packing, carry out the oxirane disinfection sterilization, get the manufactured goods of antiallergic gel nose protection medical supplies.
Two. the Performance Detection of embodiment 1 manufactured goods;
Manufactured goods to embodiment 1 detect, and are as shown in table 1:
Table 1. embodiment 1 antiallergic gel nose protection medical supplies manufactured goods Performance Detection
The manufactured goods of conclusion: embodiment 1 antiallergic gel nose protection medical supplies are filtering antibacterial and virus effectively; And intercept pollen etc. and enter respiratory tract, and do not affect human normal and breathe; Have no side effect.
One. preparation 100g antiallergic gel, 100g hydroxyethyl chitosan solution and corresponding antiallergic gel nose protection medical supplies
1. with the pure water of 0.5 gram cation locust bean gum, 20 gram simethicone, 0.5 gram ethyl hydroxybenzoate, 1.5 gram glycerol, 0.5 gram propylene glycol, 0.05 gram essence and surplus, mixing stirs evenly, and is stand-by;
2. 5 gram hydroxyethyl chitosans are dissolved in the pure water of 95 grams, make 100 gram solution;
3. selection has elasticity, gas permeable material flexible, that do not affect eupnea prepares pad pasting, the one side of pad pasting has the adhibit quality compatible with tissue, and extend alar part in its left and right sides, also be prepared with according to various nose shapes and a plurality of cut line of stretcher strain at the pad pasting upside; Pad pasting central authorities are prepared with protuberance;
4. the gas permeable material of selecting not affect eupnea prepares filter; Filter pad pasting face is applied the antiallergic gel that makes with step 1; Simultaneously prepare fine hole pattern at gel layer;
5. the hydroxyethyl chitosan solution that again filter nostril side infiltration is made with step 2, then dry;
6. filter is placed in pad pasting central authorities protuberance place; The section of left wing of pad pasting both sides and the one side of right wing part are smeared medical pressure-sensitive adhesive, carry out on the glue face and cover protective layer, make antiallergic gel nose protection medical supplies;
7. with after this finished product packing, carry out the oxirane disinfection sterilization, get the manufactured goods of antiallergic gel nose protection medical supplies.
Two. the Performance Detection of embodiment 2 manufactured goods:
Manufactured goods to embodiment 2 detect, and are as shown in table 2:
Table 2. embodiment 2 antiallergic gel nose protection medical supplies manufactured goods Performance Detection
Conclusion: embodiment 2 antiallergic gel nose protection medical supplies manufactured goods are filtering antibacterial and virus effectively; And intercept pollen etc. and enter respiratory tract, and do not affect human normal and breathe; Have no side effect.
One. preparation 100g antiallergic gel, 100g hydroxypropyl sugar juice and corresponding antiallergic gel nose protection medical supplies
1. with the pure water of 1 gram cationic sesbania gum, 30 gram simethicone, 1 gram propylparaben, 5 gram glycerol, 3 gram propylene glycol, 0.1 gram essence and surplus, mix, stir evenly stand-by;
2. 3 gram hydroxypropyl chitosans are dissolved in the pure water of 97 grams, make 100 gram solution;
3. selection has elasticity, gas permeable material flexible, that do not affect eupnea prepares pad pasting, the one side of pad pasting has the adhibit quality compatible with tissue, and extend alar part in its left and right sides, also be prepared with according to various nose shapes and a plurality of cut line of stretcher strain at the pad pasting upside; Pad pasting central authorities are prepared with protuberance;
4. the gas permeable material of selecting not affect eupnea prepares filter; Filter pad pasting face is applied the antiallergic gel that makes with step 1; Simultaneously prepare fine hole pattern at gel layer;
5. the hydroxypropyl sugar juice that again filter nostril side infiltration is made with step 2, then dry;
6. filter is placed in pad pasting central authorities protuberance place; The section of left wing of pad pasting both sides and the one side of right wing part are smeared medical pressure-sensitive adhesive, carry out on the glue face and cover protective layer, make antiallergic gel nose protection medical supplies;
7. with after this finished product packing, carry out the oxirane disinfection sterilization, get the manufactured goods of antiallergic gel nose protection medical supplies.
Two. the Performance Detection of embodiment 3 manufactured goods:
Manufactured goods to embodiment 3 detect, and are as shown in table 1:
Table 3. embodiment 3 antiallergic gel nose protection medical supplies manufactured goods Performance Detection
Conclusion: embodiment 3 antiallergic gel nose protection medical supplies manufactured goods are filtering antibacterial and virus effectively; And intercept pollen etc. and enter respiratory tract, and do not affect human normal and breathe; Have no side effect.
Embodiment 4
One. preparation 100g antiallergic gel and corresponding antiallergic gel nose protection medical supplies
1. with the pure water of 0.6 gram cation guar gum, 40 gram simethicone, 0.1 Keshan potassium sorbate, 0.5 gram glycerol, 0.5 gram propylene glycol, 0.08 gram essence and surplus, mix, stir evenly stand-by;
2. buy from the market the nano-silver biological material that the qualified diameter of 100 grams is 50nm;
3. selection has elasticity, gas permeable material flexible, that do not affect eupnea prepares pad pasting, the one side of pad pasting has the adhibit quality compatible with tissue, and extend alar part in its left and right sides, also be prepared with according to various nose shapes and a plurality of cut line of stretcher strain at the pad pasting upside; Pad pasting central authorities are prepared with protuberance;
4. the gas permeable material of selecting not affect eupnea prepares filter; Filter pad pasting face is applied the antiallergic gel that makes with step 1; Simultaneously prepare fine hole pattern at gel layer;
5. again the filter nostril surface is embrocated the nano silver material that step 2 is buied;
6. filter is placed in pad pasting central authorities protuberance place; The section of left wing of pad pasting both sides and the one side of right wing part are smeared medical pressure-sensitive adhesive, carry out on the glue face and cover protective layer, make antiallergic gel nose protection medical supplies;
7. with after this finished product packing, carry out the oxirane disinfection sterilization, get the manufactured goods of antiallergic gel nose protection medical supplies.
Two. the Performance Detection of embodiment 4 manufactured goods:
Manufactured goods to embodiment 4 detect, and are as shown in table 1:
Table 4. embodiment 4 antiallergic gel nose protection medical supplies manufactured goods Performance Detection
Conclusion: embodiment 4 antiallergic gel nose protection medical supplies manufactured goods are filtering antibacterial and virus effectively; And intercept pollen etc. and enter respiratory tract, and do not affect human normal and breathe; Have no side effect.
Claims (1)
1. antiallergic gel nose protection medical supplies, form by hiding rhinarium, antiallergic gel and natural resisting pathogenic microbes biomaterial, and it is characterized in that: described screening rhinarium is comprised of pad pasting and filter; The one side of pad pasting has adhibit quality, the pad pasting left and right sides is designed with section of left wing and right wing part, the pad pasting upside prepares a plurality of cut line, pad pasting central authorities are prepared with protuberance, filter is placed in pad pasting central authorities protuberance place, and filter is inclined upwardly, and the pad pasting face of filter is covered with the antiallergic gel, and the nostril surface of filter is covered with natural resisting pathogenic microbes biomaterial.
2, antiallergic gel nose according to claim 1 protection medical supplies is characterized in that: described pad pasting for have elasticity, stretch, gas permeable material makes, described filter is that gas permeable material is made.
3, antiallergic gel nose according to claim 1 protection medical supplies is characterized in that: described antiallergic gel, comprise following component, each component by weight percentage:
Natural plants cationic colloidal 0.1-1%
Simethicone 10-40%
Antiseptic 0.1-1%
Glycerol 0.5-5%
Propylene glycol 0.1-3%
Essence 0.01-0.1%
The purified water surplus.
4, antiallergic gel nose protection medical supplies according to claim 3, it is characterized in that: described natural plants cationic colloidal is a kind of or wantonly two kinds of mixture in cation guar gum, cation locust bean gum, Cationic Fenugreek Gum, cationic sesbania gum, cation artemisia glue, cation Radix Astragali glue;
5, antiallergic gel nose protection medical supplies according to claim 3, it is characterized in that: described antiseptic is: a kind of or wantonly two kinds of mixture in benzoic acid, sodium benzoate, sorbic acid, potassium sorbate, methyl hydroxybenzoate, ethyl hydroxybenzoate, propylparaben;
6, antiallergic gel nose protection medical supplies according to claim 1; it is characterized in that: when described natural resisting pathogenic microbes biomaterial is that mass concentration is when being the water-soluble chitosan solution of 0.1-5%; be the water-soluble chitosan solution of 0.1-5% with filter nostril side infiltration mass concentration, then dry.
7, antiallergic gel nose according to claim 6 protection medical supplies is characterized in that: described water-soluble chitosan is one or two or more kinds the mixture in carboxymethyl chitosan, hydroxyethyl chitosan, hydroxypropyl chitosan, N-trimethyl oxidation chitosan.
8, antiallergic gel nose protection medical supplies according to claim 1, it is characterized in that: described natural resisting pathogenic microbes biomaterial is the nano-silver biological material, the silver-colored simple substance nano-particle of diameter between 1-100nm.
9, the preparation method of one of according to claim 1-8 described antiallergic gel nose protection medical supplies, is characterized in that comprising the steps:
A), by said ratio, natural plants cationic colloidal, simethicone, antiseptic, glycerol, propylene glycol, essence and purified water are mixed and make the antiallergic gel after stirring evenly;
B), the preparation mass concentration is the water-soluble chitosan solution of 0.1-5%;
C), select to have elasticity, flexible, gas permeable material prepares pad pasting, the one side of pad pasting has adhibit quality, the pad pasting left and right sides is designed with section of left wing and right wing part, upside is prepared with a plurality of cut line, pad pasting central authorities are prepared with protuberance;
D), select gas permeable material to prepare filter, filter pad pasting face is covered with the antiallergic gel, prepares fine hole pattern at gel layer; Filter nostril side infiltrates dries after the water-soluble chitosan solution that mass concentration is 0.1-5% or nanometer silver is coated on filter nostril side;
E), filter is placed in pad pasting central authorities protuberance place, and filter is inclined upwardly; The section of left wing of pad pasting both sides and the one side of right wing part are smeared medical pressure-sensitive adhesive, carry out on the glue face and cover protective layer; Make antiallergic gel nose protection medical supplies.
10, the preparation method of antiallergic gel nose protection medical supplies according to claim 9; characterized by further comprising step f); with e) after the antiallergic gel nose that the makes protection medical supplies packing in step; carry out the oxirane disinfection sterilization, make the manufactured goods of antiallergic gel nose protection medical supplies.
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| CN 201110031783 CN102119879B (en) | 2011-01-28 | 2011-01-28 | Antiallergic gel nose-protecting medical supply and making method thereof |
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| CN 201110031783 CN102119879B (en) | 2011-01-28 | 2011-01-28 | Antiallergic gel nose-protecting medical supply and making method thereof |
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| CN102119879B true CN102119879B (en) | 2013-06-19 |
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| CN104629096B (en) * | 2014-07-23 | 2017-07-11 | 成都海麓生物科技有限公司 | A kind of obstruct PM2.5 and the former gel of other nasal allergies |
| CN109106683A (en) * | 2018-08-31 | 2019-01-01 | 济南秦鲁药业科技有限公司 | A kind of nose desensitization gel and preparation method |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1035821A1 (en) * | 1997-12-01 | 2000-09-20 | Minnesota Mining And Manufacturing Company | Nasal dilator |
| CN1559364A (en) * | 2004-02-27 | 2005-01-05 | 林智祥 | Method for sonre-stopping, and adhering sheet therefor |
| WO2006063339A2 (en) * | 2004-12-08 | 2006-06-15 | Ventus Medical, Inc. | Respiratory devices and methods of use |
| CN200998515Y (en) * | 2006-09-19 | 2008-01-02 | 成都通加健康科技有限公司 | Pack for nose for improving the aeration property for nasal cavity |
| CN101675905A (en) * | 2008-09-19 | 2010-03-24 | 刘根东 | Nasal septal deviation therapeutic apparatus and therapeutic method |
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2011
- 2011-01-28 CN CN 201110031783 patent/CN102119879B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1035821A1 (en) * | 1997-12-01 | 2000-09-20 | Minnesota Mining And Manufacturing Company | Nasal dilator |
| CN1559364A (en) * | 2004-02-27 | 2005-01-05 | 林智祥 | Method for sonre-stopping, and adhering sheet therefor |
| WO2006063339A2 (en) * | 2004-12-08 | 2006-06-15 | Ventus Medical, Inc. | Respiratory devices and methods of use |
| CN200998515Y (en) * | 2006-09-19 | 2008-01-02 | 成都通加健康科技有限公司 | Pack for nose for improving the aeration property for nasal cavity |
| CN101675905A (en) * | 2008-09-19 | 2010-03-24 | 刘根东 | Nasal septal deviation therapeutic apparatus and therapeutic method |
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Denomination of invention: Anti allergic gel nasal protective medical appliance and preparation method thereof Effective date of registration: 20211216 Granted publication date: 20130619 Pledgee: Wuhan area branch of Hubei pilot free trade zone of Bank of China Ltd. Pledgor: Wuhan Coupling Medicine Technology Co.,Ltd. Registration number: Y2021420000144 |
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Date of cancellation: 20230403 Granted publication date: 20130619 Pledgee: Wuhan area branch of Hubei pilot free trade zone of Bank of China Ltd. Pledgor: Wuhan Coupling Medicine Technology Co.,Ltd. Registration number: Y2021420000144 |