CN102114149A

CN102114149A - Chinese medicine preparation for treating epilepsy

Info

Publication number: CN102114149A
Application number: CN2011100419331A
Authority: CN
Inventors: 于晓瑾
Original assignee: HEILONGJIANG KANGYUAN NERVE SPECIALIZED HOSPITAL CO Ltd
Current assignee: HEILONGJIANG KANGYUAN NERVE SPECIALIZED HOSPITAL CO Ltd
Priority date: 2011-02-15
Filing date: 2011-02-15
Publication date: 2011-07-06
Anticipated expiration: 2031-02-15
Also published as: CN102114149B

Abstract

The invention relates to a Chinese medicine preparation for treating epilepsy, which has good treatment effect and little side effect. The Chinese medicine preparation is prepared from the following raw materials in parts by weight of 10-50 parts of bupleurum, 10-50 parts of scutellaria baicalensis, 10-50 parts of pinellia tuber, 10-30 parts of Chinese rhubarb, 10-40 parts of dragon bones, 10-50 parts of oyster, 10-40 parts of raw sienna, 5-20 parts of scorpion, 10-30 parts of uncaria, 5-30 parts of bombys batryticatus, 8-35 parts of Szechwan gentian, 10-35 parts of calamus through mixing and purifying into powder. The Chinese medicine preparation is verified by years of clinical experience, and is well received by patients due to obvious effect.

Description

The Chinese medicine preparation of treatment epileptics

(1), technical field

What the present invention relates to is a kind of Chinese medicine preparation, a kind of specifically Chinese medicine preparation that is used for the treatment of epileptics.

(2), background technology

Epileptics is 0.5% at the sickness rate of China, and is very common clinically.Its main clinical manifestation is: breaking out falls down to the ground, loss of consciousness, and whole body is twitched, and spits out white foams, and two are upwards turned over, and each outbreak continues 1-3 minute.Epileptics is very big to people's harm, mainly contain following some: the infringement of (1) brain function: the every outbreak of epilepsy once, brain cell damages once, secular epilepsy is shown effect repeatedly, the patient can intelligence descend, disablement gradually, even viability at last.(2) fortuitous casualty:

No matter, occur traumatic injury, scald, drowned, vehicle accident easily because of epilepsy is that time, place, environment again can not oneself control break out and fall down to the ground.(3) psychic trauma: because of epileptics often outbreak all bring influence to patient's employment, marriage, family life, thereby epileptic's ergasia is more oppressive, physical and mental health is subjected to very big influence, so to epileptics should take in time, effective way treats.

The Therapeutic Method of epileptics has western medicine and treatment by Chinese herbs at present:

One, western medicine: the medicine for the treatment of epileptics at present is a lot, is representative with the phenytoin Sodium.Its action principle mainly is epileptogenic focus discharge in the Taking Control of Epilepsy patient brain, and western thing is of short duration action time, so needs of patients for a long time, regularly, is quantitatively taken one or more antiepileptics.Yet this class drug side effect is more, takes for a long time, often occurs that gingiva thickens, side effect such as hirsutism, pachylosis, bradykinesia, spirit are poor, liver function damage, blood leucocyte minimizing, so the patient often is difficult to adhere to taking medicine.And the considerable part epileptic patient is arranged, it is invalid to heal with medicine.

Two, treatment by Chinese herbs, this product is a pure Chinese medicinal preparation, and long-term use and have small side effects, and drug effect is rapid, dosage is accurate, reliable effect.The batch process of this product has good market potential, the market demand.And this product is evident in efficacy in my institute's clinical practice for many years, is subjected to patient's welcome deeply.Through the relevant further investigation of systems such as clinical pharmacology, will declare new Chinese medicine behind the condition maturity, for this sick new force that increases is treated by China.

(3), summary of the invention

The object of the invention is to provide a kind of therapeutic effect good, the Chinese medicine preparation of the treatment epilepsy that side effect is little.

The object of the present invention is achieved like this: it by weight portion is: Radix Bupleuri 10-50 part, Radix Scutellariae 10-50 part, Rhizoma Pinelliae 10-50 part, too yellow 10-30 part, Os Draconis 10-40 part, Concha Ostreae 10-50 part, Haematitum 10-40 part, Scorpio 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Bombyx Batryticatus 5-30 part, Rhizoma Coptidis 8-35 part, Rhizoma Acori Graminei 10-35 part are made.

This prescription in clinical use for many years, and is evident in efficacy.Be only limited to clinical use at present, outside institute, sell and use in my institute.

Adopt the present invention to carry out the clinical observation test in the neural section hospital of Heilungkiang Kang Yuan, model case is described below:

Case 1, king so-and-so, man, 17 years old, people from Baiquan County, Heilongjiang Province.The patient is grand mal first, sudden faint, and syncope, slobbering, tetany, gatism is revived after about 2～3 minutes, the wake up conscious dizziness in back, headache, drowsiness, lassitude and weak.Later on every month grand mal several times, every day is petit mal for several times.Hospital is diagnosed as electroencephalogram in Xuan Wu, Beijing: focus epilepsy (right side hemisphere focus).Give Western medicine such as oral sodium valproate, fail to control.In December, 2008 comes my institute's treatment, takes 1 dose in Chinese medicine of the present invention one day, 2 sub-services after meal sooner or later.Through a treatment in month, grand mal control subtracted Western medicine 1/2 amount then, and Western medicine is removed entirely after 2 weeks.Took traditional Chinese medicine 2 months, petit mal is basic controlling also again.Through two course of therapy, conditions of patients is stable, operate as normal.Follow up a case by regular visits to not recurrence so far.

Case 2, Zhang, woman, 5 years old, people from Harbin City.Come institute to go to a doctor on July 15th, 2008.Fall down to the ground during outbreak, tic of the limbs, the eyes turning upwards, spit out white foams, go into a coma and do not know, show effect less than one minute, red tongue is yellow greasy, rolling pulse.Be diagnosed as essential epilepsy.Accept the treatment by Chinese herbs of the present invention of my institute since on August 18th, 2008, came institute's check on November 8th, 2008, transference cure, it is normal to look into electroencephalogram, stable disease, all are normal, follow up a case by regular visits to so far and do not send out.

Case 3, Zhao so-and-so, 23 years old people from Mudanjiang City of man.Morbidity in the time of 12 years old is not known people, tic of the limbs, is spat out white foams during outbreak, gnathospasma, the eyes turning upwards, should of exhaling dusk.Take phenobarbital, phenytoin Sodium, symptom are not effectively controlled, and come me institute to go to a doctor on March 6th, 2008.Have a medical check-up when examining: god is clear, language is sharp, look into the heart, lung, liver, spleen no abnormality seen, extremity activity freely, the neurologic check no abnormality seen, and tongue is talked, tongue is bored with stringy,thready and rapid pulse in vain; EEG (electrocardiogram) examination result is extensive abnormal electroencephalogram.It is controlled to take month state of an illness of Chinese medicine of the present invention, check on June 1st, 2008, and electroencephalogram is normal, and the state of an illness is steady, follows up a case by regular visits to and does not see outbreak so far.

Case 4, Lee so-and-so, 26 years old Acheng City people of Heilongjiang Province of man because of paroxysmal left limb numbness, twitch to surplus in 7 years and go to a doctor in January, 2009.Patient's dim complexion, dull expression, left limb is dumb, self-induction numbness, insomnia, cardiopalmus.Be diagnosed as localized epilepsy.After taking treatment by Chinese herbs of the present invention, it is controlled to show effect after 1 month, and look flexible, and complexion is changeed China, the amelioration of sleeping night, and cardiopalmus disappears, and the commentaries on classics of body of the tongue speckle is lacked, and follows up a case by regular visits to after 1 year, sick recovery from illness, not more not repeatedly.

Case 5, bent so-and-so, 38 years old Shuangcheng City people of Heilongjiang Province of man.Calendar year 2001 sudden onset, because of unconsciousness appears in interruption, get around, to murmur to oneself is rubbed hands and is made clicks, rattiness at ordinary times, the commentaries on classics of not getting better of treatment everywhere, come my institute in February, 2009, is diagnosed as psychomotor seizure.After taking treatment by Chinese herbs of the present invention, sb.'s illness took a favorable turn behind the two weeks, do not see the state of an illness in half a year repeatedly, follows up a case by regular visits to in January, 2011, do not see recurrence so far.

Case 6, party so-and-so, women, 34 years old Yichun peasant of Heilongjiang Province.The nineteen ninety-five outbreak is interrupted and twitched 9 years.Conscious abdominal part pain has intestinal gas to rise and feels that give a cry several seconds then before the outbreak, sudden loss of consciousness is fallen over, the tetanic contraction of whole-body muscle, head is to layback, mouthful Hu Kaihou closure is lisped, and spits out white foams, turns on the eyes, whole-body muscle clonic spasm, the upper limb flexing, two hold act, and two lower limb stretch tetanic.About 3 minutes clear-headed, and pupil is normal by big change, lethargy, the memoryless incidence in back of waking up.Take treatment by Chinese herbs of the present invention in May, 2009 behind my institute's expert diagnosis, follow up a case by regular visits to and do not see outbreak in 2 years.

Case 7, all so-and-so, male, 38 years old, the Suihua City peasant of Heilongjiang Province.Met traffic accident in 1988, and did operation of opening cranium, postoperative causes the epileptics grand mal, over 20 years, be national various big hospital treatment, the commentaries on classics of not getting better, all be that during the medication, the state of an illness is alleviated to some extent with some Western medicine and treatment by Chinese herbs, dose one subtracts the state of an illness and increases the weight of, and dosage progressively strengthens, because patient's administration time is oversize, medicine has been produced drug resistance and paid effect, and caused a series of complication, it is unstable to walk, babble.In October, 2009, come my institute to take treatment by Chinese herbs of the present invention, the state of an illness takes a turn for the better gradually after 2 months, and now, the existing time more than 2 years did not show effect.。

Case 8, seal so-and-so, man, 37 years old, the Yilan County workman of Heilongjiang Province.9 years medical histories show as loss of consciousness during outbreak, turn on two, spit out white foams, extremity are twitched, and once go ground treatments such as Beijing, Tianjin, it is not obvious to take sodium valproate, appropriate Thailand, carbamazepine therapeutic effect, and outbreak in every month 5-6 time is diagnosed as intractable epilepsy at Beijing large hospital.Its household recognizes that on the net there is the new method of this treatment epilepsy in my institute, and in May, 2010, my institute received treatment, and after taking treatment by Chinese herbs of the present invention, showing effect after two months has stopped, and takes medicine and follows up a case by regular visits to not outbreak so far.

(4), the specific embodiment

For a more detailed description to the present invention below: as according to weight portion to be: the ratio of Radix Bupleuri 10-50 part, Radix Scutellariae 10-50 part, Rhizoma Pinelliae 10-50 part, Radix Et Rhizoma Rhei 10-30 part, Os Draconis 10-40 part, Concha Ostreae 10-50 part, Haematitum 10-40 part, Scorpio 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Bombyx Batryticatus 5-30 part, Rhizoma Coptidis 8-35 part, Rhizoma Acori Graminei 10-35 part mixes each raw material, be purified to powder and make.

Claims

1. Chinese medicine preparation for the treatment of epileptics, it is characterized in that: the ratio of Radix Bupleuri 10-50 part, Radix Scutellariae 10-50 part, Rhizoma Pinelliae 10-50 part, Radix Et Rhizoma Rhei 10-30 part, Os Draconis 10-40 part, Concha Ostreae 10-50 part, Haematitum 10-40 part, Scorpio 5-20 part, Ramulus Uncariae Cum Uncis 10-30 part, Bombyx Batryticatus 5-30 part, Rhizoma Coptidis 8-35 part, Rhizoma Acori Graminei 10-35 part by weight, each raw material is mixed, is purified to powder and makes.