CN102106932A - Medicament for treating diabetic foot - Google Patents
Medicament for treating diabetic foot Download PDFInfo
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- CN102106932A CN102106932A CN2011100446911A CN201110044691A CN102106932A CN 102106932 A CN102106932 A CN 102106932A CN 2011100446911 A CN2011100446911 A CN 2011100446911A CN 201110044691 A CN201110044691 A CN 201110044691A CN 102106932 A CN102106932 A CN 102106932A
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- treating diabetic
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Abstract
A medicament for treating diabetic foot and is a capsule product which is prepared according to the following steps of: mixing honeysuckle flower, weeping forsythia, dandelion, frankincense, myrrh, cornu vervi degelatinatum, Chinese angelica, leech, earthworm, Japanese ampelopsis root and milkvetch root, crushing the materials into powder; adding water and boiling; filtering and condensing into paste and drying; crushing the dried materials into powder; feeding the powder into capsules; and sterilizing and disinfecting to form a capsule product. The medicament disclosed by the invention has the efficacies of clearing away heat and toxic material, removing necrosis and promoting granulation, promoting blood circulation and nourishing qi and blood, can be used for treating diabetic foot and has the characteristics of low expense and favorable curative effect. Through clinical observation, the cure rate of the medicament reaches 87 percent.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of the diabetes pedopathy, particularly relating to a kind of is the medicine of the treatment diabetes pedopathy of crude drug preparation with Chinese medicine.
Background technology
Diabetes pedopathy (DF) is clinical common and multiple diabetic complication.Also being one of severe complications of diabetes, is again the diabetic lethal main cause that disables.The diabetes pedopathy is the main vascular complications of diabetes, refer to mainly that diabetics loses sensibility because of neuropathy or lose mobility because of ischemia, foot disease due to the concurrent infection, its clinical manifestation are neuropathy, vascular lesion, biomechanics is unusual, ulcer of the lower limb forms and infection.Diabetes pedopathy incidence rate prolongs along with the course of disease of diabetes and the growth of patient age and increasing.Modal consequence is a chronic ulcer, and the most serious final result is amputation.
The Wagner classification of diabetic foot: 0 grade: the foot that ulcer of foot danger takes place is arranged, and skin does not have open focus.1 grade: there is ulcer on the surface, does not have infection clinically.2 grades: darker ulcer infection focus often merges soft tissue inflammation, the infection of no abscess or bone.3 grades: the degree of depth infects, with osseous tissue pathological changes or abscess.4 grades: bony defect, part toe, foot gangrene.5 grades: the big portion of foot or all gangrenous.
Western medical treatment diabetes pedopathy mainly relies on operation method to carry out, and has that the patient suffering is big, an easily recurrence, operation risk is big, expense is high shortcoming.
Summary of the invention
The purpose of this invention is to provide a kind of is the medicine of the treatment diabetes pedopathy of crude drug preparation with Chinese medicine, and this curative effect of medication is remarkable, and cure rate is satisfied.
Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:
Flos Lonicerae 20～40 Fructus Forsythiaes 20～40 Herba Taraxacis 20～40
Olibanum 7～13 Myrrhas 7～13 Cornu Cervi Degelatinatums 20～40
Radix Angelicae Sinensis 7～13 Hirudos 7～13 Pheretimas 7～13
Radix Ampelopsis 7～13 Radixs Astragali 8～16.
The medicine of above-mentioned each component can be made said peroral dosage form on any pharmaceuticss such as tablet, pill, powder, capsule, and the preferred dosage form of the present invention is a capsule.
The concrete preparation method of medicine capsule of the present invention is: said medicine is ground into fine powder, according to described parts by weight mix homogeneously, decoct with water 2～4 times, each 1～2 hour, collecting decoction, filter, be condensed into the thick paste of 60 ℃ of relative densities 1.1～1.3, after 50～60 ℃ of dryings, be ground into 100～120 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
In the prescription of the present invention, Flos Lonicerae dispelling wind-heat, removing summer-heat blood poison; Fructus Forsythiae, Herba Taraxaci heat-clearing and toxic substances removing, mass dissipating and swelling eliminating; Chinese angelica blood supplementing is invigorated blood circulation; Hirudo removing blood stasis, removing blood stasis, stimulate the menstrual flow; Olibanum blood-activating and qi-promoting, inducing menstruation to relieve menalgia, detumescence and promoting granulation; Myrrha loose blood blood stasis removing, subduing swelling and relieving pain; Radix Ampelopsis heat-clearing and toxic substances removing, removing obstruction for relieving pain, promoting tissue regeneration and ulcer healing; Cornu Cervi Degelatinatum reinforcing the kidney and supporting YANG, astringing to arrest bleeding; Pheretima heat clearing away, collateral dredging; Radix Astragali invigorating QI to consolidate the body surface resistance, evacuation of pus, expelling pus and promoting granulation; All medicine compatibilities, heat-clearing and toxic substances removing, removing the necrotic tissue and promoting granulation, blood circulation promoting and blood stasis dispelling, nourishing qi and blood treatment diabetes pedopathy are evident in efficacy.
For further investigating the clinical efficacy of drug treatment of diabetic pedopathy of the present invention, select 100 routine diabetic foot patients to carry out clinical observation on the therapeutic effect.
Clinical data:
Select outpatient's 60 examples, wherein male 54 examples, women 46 examples, 35～60 years old age.All case all meets the diagnostic criteria of " inspection method of diabetic foot (acromelic gangrene) and diagnostic criteria (draft) ".
Medical history: previously diabetic history is arranged or be admitted to hospital to be diagnosed as diabetes, diagnosis meets the diabetes diagnosis standard of WHO formulation in 1999; Clinical symptoms ten is venous plasma blood glucose 〉=11.0mmol/L immediately, or empty stomach venous plasma blood glucose 〉=7.0mmol/L, or 2 hours venous plasma blood glucose 〉=11.0mmol/L of oral glucose tolerance test.
Symptom: local swelling, flushing, scorching hot, gradually to moist necrosis, but suffer from sufficient blood for good, acra does not have obvious ischemia sign, does not have obvious rest pain.
Sign: acra festers, and infection suppurates or blackening necrosis etc. has dryness or wet gangrene performance.And meet 0-5 level Wagner classification.
Therapeutic Method:
Keep on the basis of medicine taking original diabetes, oral medicament capsule agent medicine of the present invention, each 6, was taken 3 months continuously at oral medicine of the present invention every day three times.Period in a medicine fasting raw food, irritable food such as greasy, pungent.
Criterion of therapeutical effect:
Treat relevant index and necrosis efficacy assessment standard Comprehensive Assessment curative effect with reference to diabetic complication.
Cure: clinical symptoms disappears substantially, and trouble skin of foot color restoration is normal, and wound surface heals fully.
Effectively: suffer from the ulcer of foot surrounding tissue and subside a swelling gradually, slough comes off, and secretions reduces, and surrounding skin begins ruddy, and there is the granulation tissue growth at undisguised position.
Invalid: ulcer does not heal, and gangrene spreads, and increases the weight of gradually even amputation.
Therapeutic outcome:
After treatment in continuous 3 months, 100 routine patient's sign indexs are carried out detection statistics, clinical cure 87 examples, effective 10 examples, invalid 3 examples, cure rate reaches 87%, satisfactory effect.
The specific embodiment
Embodiment 1
Each crude drug is removed impurity, and after cleaning up, pulverize separately becomes 80 purpose fine powders.
Take by weighing Flos Lonicerae 30g, Fructus Forsythiae 30g, Herba Taraxaci 30g, Olibanum 10g, Myrrha 10g, Cornu Cervi Degelatinatum 30g, Radix Angelicae Sinensis 10g, Hirudo 10g, Pheretima 10g, Radix Ampelopsis 10g, Radix Astragali 12g mix homogeneously, decoct with water 2 times, each 2 hours, collecting decoction filters, and is condensed into the thick paste of 60 ℃ of relative densities 1.1～1.3, after 60 ℃ of dryings, be ground into 120 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
Embodiment 2
Each crude drug is removed impurity, and after cleaning up, pulverize separately becomes 80 purpose fine powders.
Take by weighing Flos Lonicerae 20g, Fructus Forsythiae 20g, Herba Taraxaci 20g, Olibanum 7g, Myrrha 7g, Cornu Cervi Degelatinatum 20g, Radix Angelicae Sinensis 7g, Hirudo 7g, Pheretima 7g, Radix Ampelopsis 7g, Radix Astragali 8g mix homogeneously, decoct with water 2 times, each 2 hours, collecting decoction filters, and is condensed into the thick paste of 60 ℃ of relative densities 1.1～1.3, after 60 ℃ of dryings, be ground into 100 purpose medicated powder, in incapsulating, sterilization is made the capsule product.
Claims (2)
1. medicine for the treatment of the diabetes pedopathy is that the medicine by following portions by weight is that crude drug prepares:
Flos Lonicerae 20～40 Fructus Forsythiaes 20～40 Herba Taraxacis 20～40
Olibanum 7～13 Myrrhas 7～13 Cornu Cervi Degelatinatums 20～40
Radix Angelicae Sinensis 7～13 Hirudos 7～13 Pheretimas 7～13
Radix Ampelopsis 7～13 Radixs Astragali 8～16.
2. the medicine of treatment diabetes pedopathy according to claim 1 is characterized in that described medicine is made capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100446911A CN102106932A (en) | 2011-02-24 | 2011-02-24 | Medicament for treating diabetic foot |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011100446911A CN102106932A (en) | 2011-02-24 | 2011-02-24 | Medicament for treating diabetic foot |
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| Publication Number | Publication Date |
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| CN102106932A true CN102106932A (en) | 2011-06-29 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2011100446911A Pending CN102106932A (en) | 2011-02-24 | 2011-02-24 | Medicament for treating diabetic foot |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727570A (en) * | 2012-07-11 | 2012-10-17 | 成都中医药大学附属医院 | External pharmaceutical composition for treating diabetic foot as well as preparation method and application of external pharmaceutical composition |
| CN102772712A (en) * | 2012-08-22 | 2012-11-14 | 李佃场 | Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot |
| CN104623126A (en) * | 2015-01-12 | 2015-05-20 | 上海应用技术学院 | Medicine for treating diabetic foot and preparation method of medicine |
| CN105497324A (en) * | 2014-11-05 | 2016-04-20 | 汪兴东 | Traditional Chinese medicine for treating diabetic foot |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101716248A (en) * | 2009-12-15 | 2010-06-02 | 贾春宝 | Traditional Chinese medicine composition for treating diabetes mellitus |
-
2011
- 2011-02-24 CN CN2011100446911A patent/CN102106932A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101716248A (en) * | 2009-12-15 | 2010-06-02 | 贾春宝 | Traditional Chinese medicine composition for treating diabetes mellitus |
Non-Patent Citations (1)
| Title |
|---|
| 《国医论坛》 20020131 刘 霞，胡秀峰，李生才 中医药治疗糖尿病足近况 55－56 1－2 第17卷, 第1期 2 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102727570A (en) * | 2012-07-11 | 2012-10-17 | 成都中医药大学附属医院 | External pharmaceutical composition for treating diabetic foot as well as preparation method and application of external pharmaceutical composition |
| CN102772712A (en) * | 2012-08-22 | 2012-11-14 | 李佃场 | Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot |
| CN102772712B (en) * | 2012-08-22 | 2014-03-05 | 李佃场 | Traditional Chinese medicine composition for treating heat-toxicity, flourishing and blood stasis type diabetic foot |
| CN105497324A (en) * | 2014-11-05 | 2016-04-20 | 汪兴东 | Traditional Chinese medicine for treating diabetic foot |
| CN104623126A (en) * | 2015-01-12 | 2015-05-20 | 上海应用技术学院 | Medicine for treating diabetic foot and preparation method of medicine |
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| AD01 | Patent right deemed abandoned |
Effective date of abandoning: 20110629 |
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| C20 | Patent right or utility model deemed to be abandoned or is abandoned |