CN102105139B - 制备胃滞留剂型的方法 - Google Patents

制备胃滞留剂型的方法 Download PDF

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Publication number
CN102105139B
CN102105139B CN200980128984.9A CN200980128984A CN102105139B CN 102105139 B CN102105139 B CN 102105139B CN 200980128984 A CN200980128984 A CN 200980128984A CN 102105139 B CN102105139 B CN 102105139B
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CN
China
Prior art keywords
agent
dosage form
hydrochloride
adjuvant
dosage forms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN200980128984.9A
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English (en)
Chinese (zh)
Other versions
CN102105139A (zh
Inventor
帕斯卡尔·普兰德尔
克里斯托夫·索泽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aix Marseille Universite
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Universite de la Mediterranee Aix Marseille II
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Publication of CN102105139A publication Critical patent/CN102105139A/zh
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Expired - Fee Related legal-status Critical Current
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus

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  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CN200980128984.9A 2008-06-09 2009-06-08 制备胃滞留剂型的方法 Expired - Fee Related CN102105139B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08290529.0 2008-06-09
EP08290529A EP2133071A1 (en) 2008-06-09 2008-06-09 Process for making gastroretentive dosage forms
PCT/IB2009/005889 WO2009150514A1 (en) 2008-06-09 2009-06-08 Process for making gastroretentive dosage forms

Publications (2)

Publication Number Publication Date
CN102105139A CN102105139A (zh) 2011-06-22
CN102105139B true CN102105139B (zh) 2014-12-31

Family

ID=40219495

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980128984.9A Expired - Fee Related CN102105139B (zh) 2008-06-09 2009-06-08 制备胃滞留剂型的方法

Country Status (7)

Country Link
US (1) US9060930B2 (https=)
EP (2) EP2133071A1 (https=)
JP (2) JP5675598B2 (https=)
CN (1) CN102105139B (https=)
CA (1) CA2727206A1 (https=)
ES (1) ES2561478T3 (https=)
WO (1) WO2009150514A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
EP2444064A1 (en) * 2010-10-22 2012-04-25 Meliatys Process for making multiparticulate gastroretentive dosage forms
US9119793B1 (en) 2011-06-28 2015-09-01 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for doxycycline
WO2013114390A1 (en) * 2012-01-02 2013-08-08 Medreich Limited Gastro retentive drug delivery system of calcium supplements
CN113842362A (zh) 2012-11-14 2021-12-28 格雷斯公司 含有生物活性材料与无序无机氧化物的组合物
US10842802B2 (en) 2013-03-15 2020-11-24 Medicis Pharmaceutical Corporation Controlled release pharmaceutical dosage forms
CN103462917A (zh) * 2013-09-12 2013-12-25 南京正宽医药科技有限公司 一种用于抗病毒的阿昔洛韦片剂及其制备方法
CN103462926B (zh) * 2013-09-23 2015-09-16 淄博齐鼎立专利信息咨询有限公司 一种泛昔洛韦片剂及其制备方法
WO2015187746A1 (en) 2014-06-02 2015-12-10 Teva Pharmaceutical Industries Ltd. Expandable gastroretentive dosage form
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
CN110035718B (zh) 2016-12-02 2021-04-06 克雷西奥生物科技有限公司 胃内滞留系统
WO2019111132A1 (en) 2017-12-04 2019-06-13 Clexio Biosciences Ltd. Long acting gastric residence system
AU2018388577B2 (en) * 2017-12-18 2024-06-06 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release
CN116459226B (zh) * 2023-04-26 2025-04-18 重庆康刻尔制药股份有限公司 一种铝碳酸镁双层片及其制备方法
CN118526484A (zh) * 2024-07-26 2024-08-23 中国中医科学院中药研究所 青蒿琥酯或双氢青蒿素在制备改善罗格列酮不良反应制剂中的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235718A2 (en) * 1986-02-24 1987-09-09 Eisai Co., Ltd. Granule remaining in stomach
US5626876A (en) * 1988-02-05 1997-05-06 Lts Lohmann Therapie-Systeme Gmbh & Co., Kg Floating system for oral therapy
WO2001058424A1 (en) * 2000-02-09 2001-08-16 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Floating drug delivery composition

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK162986A (da) 1985-04-12 1986-10-13 Forest Laboratories Terapeutisk middel i enhedsdosisform
US4814178A (en) 1987-07-01 1989-03-21 Sanford Bolton Floating sustained release therapeutic compositions
US5169638A (en) * 1991-10-23 1992-12-08 E. R. Squibb & Sons, Inc. Buoyant controlled release powder formulation
ES2217410T3 (es) * 1996-04-16 2004-11-01 Novartis Consumer Health S.A. Forma de dosificacion oral de rapida desintegracion.
JP2001270827A (ja) * 2000-03-23 2001-10-02 Eisai Co Ltd ベンズイミダゾール系化合物含有錠剤
JP2002154948A (ja) * 2000-11-22 2002-05-28 Eisai Co Ltd 崩壊性に優れた錠剤
US20050202090A1 (en) * 2002-01-03 2005-09-15 Clarke Allan J. Novel pharmaceutical dosage forms and method for producing same
WO2004002445A2 (en) * 2002-06-26 2004-01-08 Cadila Healthcare Limited Novel floating dosage form
US20070269512A1 (en) * 2006-05-22 2007-11-22 Wang Wenhua W Gastroretentive sustained release formulations
US9622966B2 (en) * 2007-07-06 2017-04-18 Basf Corporation Gastroretentive composition on the basis of a water-soluble reaction product from a vinyl group-containing precursor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0235718A2 (en) * 1986-02-24 1987-09-09 Eisai Co., Ltd. Granule remaining in stomach
US5626876A (en) * 1988-02-05 1997-05-06 Lts Lohmann Therapie-Systeme Gmbh & Co., Kg Floating system for oral therapy
WO2001058424A1 (en) * 2000-02-09 2001-08-16 West Pharmaceutical Services Drug Delivery & Clinical Research Centre Limited Floating drug delivery composition

Also Published As

Publication number Publication date
EP2303241A1 (en) 2011-04-06
US9060930B2 (en) 2015-06-23
EP2133071A1 (en) 2009-12-16
JP2011522873A (ja) 2011-08-04
ES2561478T3 (es) 2016-02-26
JP2015007131A (ja) 2015-01-15
WO2009150514A1 (en) 2009-12-17
JP6054931B2 (ja) 2016-12-27
JP5675598B2 (ja) 2015-02-25
CN102105139A (zh) 2011-06-22
US20120021009A1 (en) 2012-01-26
CA2727206A1 (en) 2009-12-17
EP2303241B1 (en) 2015-11-04

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Granted publication date: 20141231

Termination date: 20170608