CN102100765A - Processing technique of peach kernels - Google Patents
Processing technique of peach kernels Download PDFInfo
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- CN102100765A CN102100765A CN2009102449315A CN200910244931A CN102100765A CN 102100765 A CN102100765 A CN 102100765A CN 2009102449315 A CN2009102449315 A CN 2009102449315A CN 200910244931 A CN200910244931 A CN 200910244931A CN 102100765 A CN102100765 A CN 102100765A
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- semen persicae
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- peach kernels
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Abstract
The invention discloses a processing technique of peach kernels, which concretely comprises the following steps of: taking crude peach kernels; clearing out; removing products subjected to damage by insects and mildew; adding proper water to blanch for 30-90s; slightly soaking the kernels into the cold water; taking out and rubbing away the seed husks; airing and then placing the kernels into a medicine frying pot and frying for 2-4 min; enabling the temperature in the pot to keep at 100-300 DEG C and keeping the surface yellow with rich aroma; taking out and cooling to obtain the peach kernels. Through the adopting of the prepared product of the peach kernels, the chemical components are obviously changed, the toxicity components of amarogentin are reduced, and the dissolution of the water-soluble components is increased, and the double purposes of synergism and attenuation after processing are achieved.
Description
Technical field
The present invention relates to a kind of concocting method of Chinese medicine, particularly relate to a kind of processing procedure of Semen Persicae.
Background technology
Semen Persicae is clinical conventional Chinese medicine, it is the dry mature seed of Rosaceae (Rosaceae) plant peach Prunus persica (L.) Batsch. and mountain peach Prunus davidiana (Carr.) Franch., bitter in the mouth, sweet, property is put down, go into the heart, liver, large intestine channel, effect with blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation is usually used in diseases such as amenorrhea, dysmenorrhea, mass in the abdomen mass in the abdomen, traumatic injury, dryness of the intestine constipation.The Semen Persicae pharmacologically active is clear and definite, and clinical efficacy is definite.How to be used as medicine in history with the process of preparing Chinese medicine.Semen Persicae is that " peeling is sharp " gives birth to usefulness in " the beautiful letter warp of golden plaque ", and Collective Notes to the Canon of Materia medica is said: " soup softens, and flogs peeling ", and Remedies Left Over by Ghosts carries: " peeling is fried ", Li Shizhen (1518-1593 A.D.) argumentation Semen Persicae processed product is renderd a service and is distinguished the road: " living the using of the suitable gross weight point of Semen Persicae promoting the circulation of blood; Moisturize and blood, should soup soak the sharp parching to brown of peeling with or Testa Tritici with frying or charred medicinal herb with its property retained, each is with this book, two core persons are poisonous, and are not edible ".Promptly treat different diseases, adopt different concocting methods." technology of clean Semen Persicae, Dan Semen Persicae and Semen Persicae (parched) that Chinese pharmacopoeia 2005 editions is recorded is: with raw peach kernel reject impurity and shrivelled, go mouldy and underproof Semen Persicae such as damage by worms, clean Semen Persicae after selecting is put into boiling water stir a moment, make kind of skin by shrinkage to unfolding, can rub with the hands when going, pull out, put into cold water, remove kind of a skin, dry.Get the Dan Semen Persicae then as in the heat pot, fry to yellow with slow fire, taking-up cools, and the time spent smashs to pieces.At present, the processing procedure of Semen Persicae is fixing and unified, and the effective ingredient that the Semen Persicae after feasible the process of preparing Chinese medicine contains is not quite similar, and affects the treatment.
Effective ingredient in the Semen Persicae is an amygdaloside, and amygdaloside is also referred to as laetrile, extensively is present in the seed of multiple rosaceous plant fruits such as Fructus Pruni, peach, Fructus Pruni salicinae, Fructus Mali pumilae, Fructus Crataegi, Folium Eriobotryae, and especially content is more in Semen Armeniacae Amarum, greatly about 2%～3%.Amygdaloside is the active ingredient in the Chinese medicine Semen Armeniacae Amarum, and it has become expelling phlegm for arresting cough agent, complementary cancer therapy drug pharmaceutically commonly used.The amygdaloside molecular structure is made up of a unit benzaldehyde, a unit hydrocyanic acid and two glucose unit.Its molecular formula is C
20H
27NO
11, isomer D type and L type.
The research explanation, the toxicity of amygdaloside oral administration is that amygdaloside is produced more hydrocyanic acid by enteric microorganism hydrolysis meeting greater than the reason of intravenously administrable.Microorganism is suppressed in the mouse intestinal if amygdaloside through handling, makes, and then the phenomena of mortality do not appear in gastrointestinal administration amygdaloside 300mg/kg, and as unprocessed, then the same dose mortality rate is 60%.Human oral amygdaloside 4g every day continues two weeks or 1 month visible toxic reaction of intravenous injection, sees that so that digestive system comparatively more it is early rich to show as ECG T wave change, room in addition, and above toxic reaction all can disappear after the drug withdrawal.If dosage is kept to oral 0.6～1g every day, then can avoid toxicity.
Therefore when handling Semen Persicae, the content of amygdaloside must be controlled in certain scope.At present in order to adapt to the needs of industrialized great production, make processing procedure science, the standard of Semen Persicae, the effective ingredient that the Semen Persicae that the process of preparing Chinese medicine is come out contains has consistent scope, the quality that Semen Persicae is concocted holds good security, be necessary the processing procedure of Semen Persicae is in depth studied, thereby find out a kind of easy to operate, stable and controllable, and meet the processing procedure of big production, and optimize optimal processing parameter, satisfy Semen Persicae and concoct quality of production management standardization and clinical needs.
Summary of the invention
In order to solve the inconsistent of Semen Persicae processing procedure parameter, make the interior active constituent content of Semen Persicae inconsistent, curative effect is produced the problem of certain influence, the invention provides a kind of best processing procedure of Semen Persicae, make its easy to operate, stable and controllable, reach the process of preparing Chinese medicine purpose of attenuation synergistic, and meet big production processing procedure, concoct requirement of quality of production management regulation and clinical needs to adapt to Semen Persicae.The present invention has carried out orthogonal optimum seeking and has determined technological parameter also at the technology of each link of the Semen Persicae processing process of preparing Chinese medicine.
The concrete scheme that the present invention adopts is:
A kind of processing procedure of Semen Persicae is: get raw peach kernel, clean, remove and damage by worms and the product that go mouldy, the water that adds 5～15 times of amounts of the Semen Persicae weight system 30s～90s that scalds puts in the cold water and soaks slightly, take out then to rub with the hands and remove kind of a skin, dry parch 2～4min in the rearmounted medicine cookeding pot, 100 ℃～300 ℃ of kettle temperatures, the surface is yellow, give off a strong fragrance, taking-up cools promptly.
For further optimizing technological parameter, in the Semen Persicae concocted technology,, adopt L in conjunction with the actual production of industrialization decoction pieces
9(3
3) orthogonal test, water medicine ratio when scalding system in conjunction with the production actual selection, the system of the scalding time, parch time three factors are carried out new frying process and are investigated, as index components, carry out comprehensive grading with amygdaloside content, the Semen Persicae (parched) processing procedure that optimizes is for getting raw peach kernel, clean, remove and damage by worms and the product that go mouldy, the water that adds 10 times of amounts of the raw peach kernel weight system 60s that scalds puts in the cold water and soaks slightly, take out then to rub with the hands and remove kind of a skin, dry parch 3min in the rearmounted medicine cookeding pot, 100 ℃～170 ℃ of kettle temperatures, the surface is yellow, give off a strong fragrance, taking-up cools promptly.
This method is by repeatedly experimental verification, and is simple to operate, and the Semen Persicae steady quality all can reach the purpose of efficacy enhancing and toxicity reducing through assay, so this concocting method is fit to suitability for industrialized production.Specifically ask for an interview table 1 and table 2.
Table one empirical factor water-glass
Table two L9 (33) orthogonal design table
The specific embodiment
Below in conjunction with specific embodiment the present invention is described in further detail.
Embodiment one
Get and clean, remove and damage by worms and the raw peach kernel 100g of the product that go mouldy, add 10 times of water gagings system 60s that scalds, put in the cold water and soak slightly, take out then to rub with the hands and remove kind of a skin, dry parch 3min in the rearmounted medicine cookeding pot, 100 ℃～170 ℃ of kettle temperatures, the surface is yellow, gives off a strong fragrance, and takes out to cool promptly.
Embodiment two
Get and clean, remove and damage by worms and the raw peach kernel 500g of the product that go mouldy, add 15 times of water gagings system 90s that scalds, put in the cold water and soak slightly, take out then to rub with the hands and remove kind of a skin, dry parch 4min in the rearmounted medicine cookeding pot, 210 ℃～300 ℃ of kettle temperatures, the surface is yellow, gives off a strong fragrance, and takes out to cool promptly.
Embodiment three
Get and clean, remove and damage by worms and the raw peach kernel 1000g of the product that go mouldy, add 5 times of water gagings system 30s that scalds, put in the cold water and soak slightly, take out then to rub with the hands and remove kind of a skin, dry parch 2min in the rearmounted medicine cookeding pot, 100 ℃～150 ℃ of kettle temperatures, the surface is yellow, gives off a strong fragrance, and takes out to cool promptly.
Through above processing procedure, make that the content of amygdaloside remains in the safe scope in the Semen Persicae.As XUEFU ZHUYU JIAONANG dose every day is 4.8g, wherein contains Semen Persicae 0.768g.Every g by amygdaloside content maximum in the table 2 contains 58.94mg calculating, and the content of amygdaloside is 45.266mg in its XUEFU ZHUYU JIAONANG, within the numerical value of safety.Therefore the present invention has guaranteed the curative effect and the safety of Semen Persicae.
Claims (2)
1. the processing procedure of a Semen Persicae, it is characterized in that: get raw peach kernel, clean, remove and damage by worms and go mouldy product, the water that adds 5～15 times of amounts of the raw peach kernel weight system 30s～90s that scalds, put in the cold water and soak slightly, take out then to rub with the hands and remove kind of a skin, dry parch 2～4min in the rearmounted medicine cookeding pot, 100 ℃～300 ℃ of kettle temperatures, the surface is yellow, gives off a strong fragrance, and takes out to cool promptly.
2. the processing procedure of a kind of Semen Persicae according to claim 1, it is characterized in that: get raw peach kernel 100g, clean, remove and damage by worms and go mouldy product, the water that adds 10 times of amounts of the raw peach kernel weight system 60s that scalds, put in the cold water and soak slightly, take out then to rub with the hands and remove kind of a skin, dry parch 3min in the rearmounted medicine cookeding pot, 100 ℃～170 ℃ of kettle temperatures, the surface is yellow, gives off a strong fragrance, and takes out to cool promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102449315A CN102100765A (en) | 2009-12-18 | 2009-12-18 | Processing technique of peach kernels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009102449315A CN102100765A (en) | 2009-12-18 | 2009-12-18 | Processing technique of peach kernels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102100765A true CN102100765A (en) | 2011-06-22 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009102449315A Pending CN102100765A (en) | 2009-12-18 | 2009-12-18 | Processing technique of peach kernels |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963419A (en) * | 2016-05-11 | 2016-09-28 | 天津大学 | Medicine composition with attenuated peach kernels |
| CN108567838A (en) * | 2018-08-01 | 2018-09-25 | 师伟 | A kind of peach kernel processing method of enhancing Guizhi Fuling Pills in Treating adenomyosis |
-
2009
- 2009-12-18 CN CN2009102449315A patent/CN102100765A/en active Pending
Non-Patent Citations (1)
| Title |
|---|
| 马新华，熊鹰，等: "桃仁炮制研究初探", 《黑龙江中医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963419A (en) * | 2016-05-11 | 2016-09-28 | 天津大学 | Medicine composition with attenuated peach kernels |
| CN108567838A (en) * | 2018-08-01 | 2018-09-25 | 师伟 | A kind of peach kernel processing method of enhancing Guizhi Fuling Pills in Treating adenomyosis |
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Application publication date: 20110622 |