CN102091174A

CN102091174A - Medicament for treating psoriasis and preparation method thereof

Info

Publication number: CN102091174A
Application number: CN2011100263662A
Authority: CN
Inventors: 牛登林; 牛承龙
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-01-21
Filing date: 2011-01-21
Publication date: 2011-06-15
Anticipated expiration: 2031-01-21
Also published as: CN102091174B

Abstract

The invention relates to a medicament, in particular to a medicament which is prepared from multiple traditional Chinese medicines serving as raw materials and is used for treating psoriasis. The invention also relates to a preparation method of the medicament. The medicament mainly solves the problems of long treatment period, serious side effect, medicament resistance, easy relapse, cure of symptoms but not root causes and undesirable curative effect of the conventional medicament for treating the psoriasis in clinic. The medicament for treating the psoriasis comprises the following raw material medicaments in part by weight: 50 to 70 parts of honeysuckle, 50 to 70 parts of Indian buead, 20 to 50 parts of raw rehmannia root, 6 to 12 parts of trogopterus dung, 6 to 9 parts of safflower and 30 to 80 parts of root of red-rooted salvia. The medicament is prepared by a simple preparation method, free from side effects, can cure the patient in a short period without bringing extra body damage to the patient, avoids arousing medicament resistance, and has remarkable curative effect and high cure rate.

Description

A kind of antipsoriatics thing and preparation method thereof

Technical field

The present invention relates to a kind of medicine, particularly a kind of is the antipsoriatics thing of feedstock production with the plurality of Chinese, the invention still further relates to the preparation method of this medicine.

Background technology

Psoriasis is a kind of common chronic, recurrent, and struvite dermatosis, what wherein sickness rate was higher is homeliness type psoriasis and pustular psoriasis.Treat psoriasis at present clinically and mainly adopt operation catgut embedding for treatment, Western medicine or Chinese medicine, the cycle of operation catgut embedding for treatment is long, sunkens cord for a long time patient body is caused to a certain degree injury, and side effect is big; The western medicine psoriasis mainly is some hormone medicines, takes easily for a long time and develops immunity to drugs, and easily recurrence; Also have some to be used for the treatment of psoriasic Chinese medicine at present, but cure the symptoms, not the disease mostly, treatment cycle is long, and curative effect is not remarkable.

Summary of the invention

The present invention is primarily aimed at that present clinical treatment psoriasis exists that treatment cycle is long, side effect greatly, easily develop immunity to drugs, easily recur, cure the symptoms, not the disease, the inapparent problem of curative effect, and provide a kind of treatment cycle to lack, have no side effect, do not have Drug resistance, do not recur, treating both the principal and secondary aspects of a disease, antipsoriatics thing evident in efficacy.

The invention still further relates to the preparation method of this medicine.

Antipsoriatics thing of the present invention is to be crude drug with following parts of medicines by weight:

Flos Lonicerae 50～70, Poria 50～70, Radix Rehmanniae 20～50, Oletum Trogopterori 6～12, Flos Carthami 6～9, Radix Salviae Miltiorrhizae 30～80.

Medicine of the present invention can be made any dosage form on the pharmaceutics, and as decoction, tablet, pill, powder, capsule etc., wherein the preferred dosage form of the present invention is a honey pill agent.

The preparation method of honeyed pill of the present invention is: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned parts by weight earlier, be ground into 80～120 purpose fine powders, the Mel that adds 1～1.5 times of amount in fine powder is mixed well then, makes honeyed pill according to the manufacture method sterilization of routine by metering.

In the prescription of the present invention, Flos Lonicerae sweet in the mouth cold in nature, have antibacterial, antiviral, antiinflammatory, analgesic, regulate function such as immunity; The Poria slightly sweet flavor is flat, has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, effects such as mind tranquilizing and the heart calming; The Radix Rehmanniae sweet-bitter flavor is cold in nature, has YIN nourishing and the production of body fluid promoting, effects such as clearing away heat and cooling blood; The Oletum Trogopterori sweet-bitter flavor is warm in nature, has promoting blood circulation and stopping pain, effects such as removing stasis to stop bleeding; The Flos Carthami acrid in the mouth is warm in nature, has effects such as promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain; The little hot cold nature of Radix Salviae Miltiorrhizae bitter in the mouth; Has blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, effects such as removing heat from blood detumescence.

For showing the present invention to the psoriasis treatment effect, the present invention has carried out clinical observation on the therapeutic effect to 200 routine psoriatics, and the result shows: effective percentage is 95%, and cure rate is 93%, and is specific as follows:

Homeliness type psoriatic 100 examples, symptom: occur patch or speckle on the skin, there are thicker silvery white phosphorus bits on the surface, out-of-shape, and what have has map or an island sample outward appearance, the skin lesion that has is less, be the Caulis et folium pavettae hongkongensis outward appearance, the squama layer constantly comes off, and wipes scurf gently off and can see the red film of very thin one deck, strike off red film and can see slight petechia, itch all over; Taking medicine of the present invention after 20～50 days, no longer itches in the affected part, and the silvery white phosphorus bits of skin surface come off, and skin is little red, continues to take medicine of the present invention and fully recovers after 20～40 days.

Pustule type psoriatic 100 examples: symptom: at the both hands palm and toes portion the symmetry erythema is arranged, occur the pustule that syringe needle arrives chestnut Mi Daxiao greatly on the erythema, approximately 1-2 is dry voluntarily after week, has new pustule to occur behind the desquamation again, repeatedly outbreak; Took medicine of the present invention 20～50 days, pustule is dry, and the erythema area reduces, and color shoals, and continues to take medicine of the present invention 20～40 days, and erythema disappears, recovery from illness.

Model case is as follows:

Patient Lee: man, 50 years old, suffered from the homeliness type psoriasis 8 years, speckle shape erythema and squama are arranged on one's body, desquamation decortication back skin damage is serious, anasarca is very itched and is impatient at, neck, oxter, inguinal lymph nodes enlargement, constipation, loss of appetite four months can not be controlled after injecting 5 bottles of import methotrexates and multiple therapy, and the state of an illness progressively increases the weight of, work, neither can normally the carrying out of life, took medicine of the present invention 30 days, effect is remarkable, and skin lesion heals gradually, scratchiness disappears, continued to take 20 days, it is normal that skin recovers, and consolidates and take recovery from illness after 10 days.

Patient Wang, woman, 45 years old, suffered from the homeliness type psoriasis 15 years, shirtfront back is all surrounded one by squama, xerosis cutis, desquamation, pruritus, and taking Western medicine all is to take effect for the first time, drug withdrawal is recurrence just, take 20 days scurfs of medicine of the present invention and begin to come off, the skin lesion area dwindles gradually, after 40 days, clinical symptoms is eliminated substantially, consolidates and takes recovery from illness after 10 days.

Patient Lee, man, 39 years old, suffered from the homeliness type psoriasis 7 years, psoriasis is long more many more on one's body for many years, joins together, the whole body desquamation, painful hard to bear, take medicine of the present invention after 25 days, the state of an illness is clearly better, and about 40 days, the erythra of bulk begins to disappear on one's body, only surplus a little pigmentation spots, the affected part healing is continued to strengthen and was taken medicine 20 days, transference cure, patient's recovery from illness.

Patient Zhang, woman, 25 years old, suffered from the pustule type psoriasis 3 years, earlier arm occur point-like erythema, after develop into pustule, approximately 1-2 is dry voluntarily after week, there is the new pustule that differs in size to occur behind the desquamation again, acutely scratches where it itches, have difficulty in going to sleep, every spring and autumn and winter, state of an illness rapid deterioration was taken medicine of the present invention 30 days, pustule is dry, and the erythema area reduces, and color shoals, continued to take medicine of the present invention 40 days, erythema disappears, patient's recovery from illness.

Patient Wang, the man, 55 years old, suffered from the pustule type psoriasis 5 years, the cause of disease is to feel the trick discomfort after drenching with rain owing to suffering from cold, and works the symmetry erythema that differs in size subsequently in trick, the big pimple of syringe needle appears on the erythema, pustule is dry voluntarily after about 10 days, has new pustule to occur behind the desquamation again, repeatedly outbreak; Took medicine of the present invention 35 days, pustule is dry, and the erythema area reduces, and color shoals, and continues to take medicine of the present invention 30 days, and erythema disappears, patient's recovery from illness.

Process for preparing medicine of the present invention is simple, have no side effect, patient's life cycle is short and can not bring extra actual bodily harm to the patient, can not develop immunity to drugs and evident in efficacy, cure rate is high.

The specific embodiment

Embodiment 1

Take by weighing raw material by following proportioning:

50 kilograms of Flos Loniceraes, 50 kilograms in Poria, 20 kilograms of Radix Rehmanniae, 6 kilograms of Oletum Trogopteroris, 6 kilograms on Flos Carthami, 30 kilograms of Radix Salviae Miltiorrhizaes.

Concrete preparation method: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned weight, be ground into 80 purpose fine powders, in fine powder, add 162 kilograms of Mel then and mix well, make honeyed pill by metering according to the manufacture method sterilization of routine.

Embodiment 2

Take by weighing raw material by following proportioning:

60 kilograms of Flos Loniceraes, 60 kilograms in Poria, 35 kilograms of Radix Rehmanniae, 9 kilograms of Oletum Trogopteroris, 7 kilograms on Flos Carthami, 50 kilograms of Radix Salviae Miltiorrhizaes.

Concrete preparation method: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned weight, be ground into 100 purpose fine powders, in fine powder, add 265 kilograms of Mel then and mix well, make honeyed pill by metering according to the manufacture method sterilization of routine.

Embodiment 3

Take by weighing raw material by following proportioning:

70 kilograms of Flos Loniceraes, 70 kilograms in Poria, 50 kilograms of Radix Rehmanniae, 12 kilograms of Oletum Trogopteroris, 9 kilograms on Flos Carthami, 80 kilograms of Radix Salviae Miltiorrhizaes.

Concrete preparation method: Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of getting above-mentioned weight, be ground into 120 purpose fine powders, in fine powder, add 430 kilograms of Mel then and mix well, make honeyed pill by metering according to the manufacture method sterilization of routine.

Claims

1. antipsoriatics thing is characterized in that with following parts of medicines by weight be crude drug:

2. antipsoriatics thing according to claim 1 is characterized in that said medicine is made honeyed pill.

3. the preparation method of the described antipsoriatics thing of claim 2, it is characterized in that getting earlier Flos Lonicerae, Poria, Radix Rehmanniae, Oletum Trogopterori, Flos Carthami and the Radix Salviae Miltiorrhizae mix homogeneously of above-mentioned parts by weight, be ground into 80～120 purpose fine powders, the Mel that adds 1～1.5 times of amount in fine powder is mixed well then, makes honeyed pill according to the manufacture method sterilization of routine by metering.