CN102085319A - Medicament for treating verruca plana and preparation method thereof - Google Patents

Medicament for treating verruca plana and preparation method thereof Download PDF

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CN102085319A
CN102085319A CN 201110022078 CN201110022078A CN102085319A CN 102085319 A CN102085319 A CN 102085319A CN 201110022078 CN201110022078 CN 201110022078 CN 201110022078 A CN201110022078 A CN 201110022078A CN 102085319 A CN102085319 A CN 102085319A
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verruca plana
radix
medicine
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CN102085319B (en
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王涛
王建民
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Abstract

The invention relates to a medicament for treating verruca plana and a preparation method thereof, belonging to the technical field of treatment of verruca plana based on traditional Chinese medicine. The medicament for treating verruca plana is prepared from the following raw materials in parts by weight: 30-45 parts of radix isatidis, 15-20 parts of lithospermum, 30-40 parts of dandelion, 20-30 parts of rhizoma cyperi, 10-15 parts of red paeonia, 20-30 parts of radix astragali, 15-24 parts of radix sophorae subporstratae, 20-30 parts of coix seed, 15-20 parts of equisetum, 20-30 parts of isatis leaf, 30-45 parts of honeysuckle flower, 15-20 parts of kuh-seng and 9-12 parts of phellodendron bark. The preparation method comprises the following steps: a. weighing various raw materials according to required parts by weight: b. putting the weighed raw materials in a medicine tank, and adding water to soak the raw materials; c. decocting with sharp fire until the decoction is boiling, then decocting with soft fire for 20-40 minutes, and filtering out the liquor; and d. adding water into the medicine tank, decocting with sharp fire until the decoction is boiling, then decocting with soft fire for 20-30 minutes, leaching the liquor, and evenly mixing the liquor with the liquor leached for the first time. The medicament for treating verruca plana is a pure traditional Chinese medicine preparation, and is safe to take; no scar is left after the verruca plana heals; and the medicament for treating verruca plana is suitable for patients who suffer from verruca plana which has a long course and is easy to recur.

Description

A kind of medicine for the treatment of verruca plana and preparation method thereof
One, technical field
The present invention relates to a kind of medicine of using the treatment by Chinese herbs verruca plana and preparation method thereof, belong to treatment by Chinese herbs verruca plana technical field.
Two, background technology
Verruca plana is by the caused benign neoplasm of human papillomavirus (HPV) skin infection mucosa, verruca plana is sent out in teenager well, claim flat wart again, be commonly called as " wart on the thousand ", how by due to HPV3,5,8,9,10 types, good sending out in face, the back of the hand and forearm damaged and is normal color of the leather or light brown about 2~4mm diameter or the big slightly flat pimple of circle, ellipse or polygon, surface smoothing, boundary is obvious.Damage that normal majority is dispersed in or intensive, as through scratching, then skin lesion can be beading along scratch and arranges, i.e. self inoculation reaction or claim the Koebner phenomenon.General no conscious sympton or idol have little itching.The traditional Chinese medical science thinks that primary disease is the body weakness, the gas of affection due to external wind and heat noxious dampness, and exopathogen is taken advantage of a weak point, and stays the resistance skin, strongly fragrant and heat-transformation, pyretic toxicity accumulates in blood system, and heat in blood is sent out with outer poison rich knot skin and is wart.
The western medical treatment verruca plana is external acid, alkali electroless medicine etch, laser burn method, cold method of liquid nitrogen and immunomodulator treatment etc.Though can reach short term effect, ubiquity is the situation of recurrence easily.
Three, summary of the invention
The traditional Chinese medical science thinks that verruca plana is the body weakness, the gas of affection due to external wind and heat noxious dampness, and exopathogen is taken advantage of a weak point, and stays the resistance skin, strongly fragrant and heat-transformation, pyretic toxicity accumulates in blood system, and heat in blood is sent out with outer poison rich knot skin and is various warts.The objective of the invention is to solve the deficiency that western medical treatment verruca plana technology exists, a kind of medicine that adopts the treatment by Chinese herbs verruca plana and preparation method thereof is provided.
The traditional Chinese medical herbal treatment verruca plana is based on heat-clearing and toxic substances removing, cooling blood and dissolving stasis, is equipped with that QI invigorating is set upright, the damp eliminating eliminating stagnation.Evil poison is eliminated, and pent-up must be loose, and the wart body is come off and recovers.
The present invention is achieved through the following technical solutions:
A kind of medicine for the treatment of verruca plana, its special character is: the raw material that comprises following weight portion in the described medicine:
9~12 parts of 30~45 parts of Radix Isatidis, 15~20 parts of Radix Arnebiae (Radix Lithospermi)s, 30~40 parts of Herba Taraxaci, 20~30 parts of Rhizoma Cyperis, 10~15 parts of Radix Paeoniae Rubra, 20~30 parts of the Radixs Astragali, 15~24 parts of Radix Sophorae Tonkinensiss, 20~30 parts of Semen Coiciss, 15~20 parts of Herba Equiseties Hiemalis, 20~30 parts of Folium Isatidiss, 30~45 parts of Flos Loniceraes, Radix Sophorae Flavescentis 15~20g part, Cortex Phellodendri.
Manufacturing method for above mentioned medicine, its special character is may further comprise the steps:
A, take by weighing various raw materials according to required weight portion;
B, the various raw materials that will take by weighing are put into medicinal cupping, add water 500-600 part by weight, soak 20-40 minute;
C, very hot oven are fried boiling, and change slow fire again and fry in shallow oil 20-40 minute, leach medicinal liquid;
D, add water 350-450 part again in medicinal cupping, the very hot oven back slow fire that is fried boiling was fried in shallow oil 20-30 minute, the leaching medicinal liquid and with leaching first time medicinal liquid mixing.
Drug administration method of the present invention: respectively obey 150 milliliters on an empty stomach every day sooner or later, and two weeks were a course of treatment.The period in a medicine irritable food that avoids pungent food.
We are pure Chinese medicinal preparation, and no soda acid medicine corrosivity does not also have liver that endo-medicine causes, renal damage, more do not have the causalgia that disappears due to the laser liquid nitrogen, and back preventing from scar more.With the passing of time the present invention is applicable to the course of disease, and the patient who shows effect repeatedly.
The present invention treats various raw-material main effects in the medicine of verruca plana:
Radix Isatidis: heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.This product antipyretic and antidote functions is similar to Folium Isatidis, uses always and controls fire-toxin heat syndromes such as epidemic febrile disease, macule, erysipelas, mumps and carbuncle sore tumefacting virus, still controls the major part pestilent toxicity, women's head-ornaments redness, the card of discomfort in the throat.
Radix Arnebiae (Radix Lithospermi): removing heat from blood and promoting blood circulation, detoxifcation rash.Be used for measles or other calentura, because excessive noxious heat, and macule is sent out the card of not smooth or macular eruption being dark-purple thoroughly.The removing pathogenic heat from blood and toxic substance from the body effect is arranged, also can be used for carbuncle sore furuncle and phyma, eczema, vulvitis, scald etc.
Herba Taraxaci: heat-clearing and toxic substances removing dampness removing.This product heat-clearing and toxic substances removing, the effect of eliminating carbuncle eliminating stagnation is similar to Herba Violae, is usually used in furunculosis and acute mastitis, and single with effective, bright product are good especially, the dampness removing effect of still holding concurrently.
Rhizoma Cyperi: depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving.Be longer than depressed liver-energy dispersing and QI regulating, pain relieving, be used for the dyspepsia due to the depressed emotion, the chest and diaphragm painful abdominal mass is vexed, cards such as vomiting acid regurgitation, trusted subordinate's pain, the side of body expand, distending pain of the breast, colic.
Radix Paeoniae Rubra: clearing away heat and cooling blood, stasis-dispelling and pain-killing.The effect of this product clearing away heat and cooling blood is preferable, is usually used in fever of the body crimson tongue, macule, and the cards such as Tu Xue, Button blood of bleeding due to blood-heat due to the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, and other controls amenorrhea, traumatic injury.
The Radix Astragali: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, inducing diuresis to remove edema.Be important Qi-tonifying drug, be good at the elevate a turnable ladder yang-energy.Be used for the fatigue and weakness due to the deficiency of vital energy, the hyperhidrosis of losing heart, loose stool diarrhoea, and sinking of QI of middle-JIAO, proctoptosis, cards such as uterine prolapse.Can tonification defend outer yang-energy and strengthening superficial resistance to stop perspiration.Be used for insufficiency of vital energy and blood, skin infection difficulty in discharging of pus, or lose and not close up for a long time after broken, this product can invigorating QI and blood and promoting pus discharge and tissue regeneration strengthening.Be used for that deficiency of vital energy spleen is weak, edema, dysuria, this product has the merit of QI invigorating and diuretic concurrently.
Radix Sophorae Tonkinensis: heat-clearing and toxic substances removing, throat.Energy heat-clearing and toxic substances removing throat for controlling the laryngopharynx swelling and pain key medicine, is used for pyretic toxicity and pents up, laryngopharynx swelling and pain, and the lighter is usefulness singly, the weight person side of closing compatibility.
Semen Coicis: promoting diuresis to eliminate damp pathogen, eliminating impediment, clearing away heat and discharging pus, invigorating the spleen to arrest diarrhea.Be used for edema, cards such as beriberi swelling shank, dysuria.Also can be used for cards such as humidity hysteresis flesh table meridians, rheumatic arthralgia or spasm of the limbs.The clearing away heat and discharging pus effect is arranged, can go up clearing away lung-heat, the diarrhea the intestines and stomach is wet, can the spleen invigorating eliminating dampness by diuresis and antidiarrheal.
The Herba Equiseti Hiemalis: dispelling wind heat, move back corneal nebula.The effect of dispelling wind and heat pathogens and improving acuity of vision and removing nebula is arranged, and usefulness is controlled headache conjunctival congestion, the many tear disease due to the wind heat.
Folium Isatidis: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing.Be used for the epidemic febrile disease pyretic toxicity and send out speckle, have stronger heat-clearing and toxic substances removing, the effect of blood cooling and ecchymoses removing.The heat in blood poison is contained, and sending out is that erysipelas, aphtha, laryngopharynx swelling and pain etc. can singly be used.
Flos Lonicerae: heat-clearing and toxic substances removing.This product antipyretic and antidote functions is rather good, has the effect that light a surname evacuates, and is applicable to affection due to external wind and heat, epidemic febrile disease, and the card of hyperactivity of toxic heat such as carbuncle sore furuncle and phyma.Also be used for toxic-heat and blood stasis.
Radix Sophorae Flavescentis: heat clearing and damp drying, wind dispelling insecticide, diuresis.Be used for cards such as jaundice due to damp-heat, dysentery leucorrhea, the energy heat clearing and damp drying is used for skin pruritus, impetigo, scabies, all cards of leprosy, energy dispelling wind for relieving itching, parasite killing.
Cortex Phellodendri: clearing away dryness is wet, lets out fire-toxin, reducing the asthenic fever.Heat clearing and damp drying and antidotal effect and Rhizoma Coptidis are similar, are mainly used in cards such as damp-heat dysentery, jaundice, leucorrhea, sufficient swelling and pain in knee and pyretic stranguria.Also quite effective with controlling card such as sore and toxic eczema again, with controlling cards such as fever due to yin deficiency, hectic fever due to YIN-deficiency night sweat and seminal emission, reducing the asthenic fever arranged, make the energy of fire mutually.
We's compatibility has heat-clearing and toxic substances removing, cooling blood and dissolving stasis, and QI invigorating is set upright, the merit of damp eliminating eliminating stagnation, and pyretic toxicity is removed, and blood stasis is dispelled, and healthy energy is multiple, and damp is loose, and the wart body is come off, and meridians are unobstructed and recover.Having mutual synergism in the prescription between the various medicines, the various verruca plana due to the parillomarvirus infections such as verruca vulgaris, plantar wart, verruca plana, condyloma acuminatum are had extraordinary curative effect, is a kind of medicine for the treatment of viral disease safely and effectively.
Four, the specific embodiment
Below provide the specific embodiment of the present invention, be used for formation of the present invention is further specified.
Embodiment 1
A kind of medicine for the treatment of verruca plana comprises the raw material of following weight portion in the medicine:
30 parts of Radix Isatidis, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 30 parts of Herba Taraxaci, 20 parts of Rhizoma Cyperis, 10 parts of Radix Paeoniae Rubra, 20 parts of the Radixs Astragali, 15 parts of Radix Sophorae Tonkinensiss, 20 parts of Semen Coiciss, 15 parts of Herba Equiseties Hiemalis, 20 parts of Folium Isatidiss, 30 parts of Flos Loniceraes, 15 parts of Radix Sophorae Flavescentiss, 9 parts of Cortex Phellodendris.
Embodiment 2
A kind of medicine for the treatment of verruca plana comprises the raw material of following weight portion in the medicine:
40 parts of Radix Isatidis, 18 parts of Radix Arnebiae (Radix Lithospermi)s, 35 parts of Herba Taraxaci, 25 parts of Rhizoma Cyperis, 12 parts of Radix Paeoniae Rubra, 25 parts of the Radixs Astragali, 20 parts of Radix Sophorae Tonkinensiss, 25 parts of Semen Coiciss, 18 parts of Herba Equiseties Hiemalis, 25 parts of Folium Isatidiss, 40 parts of Flos Loniceraes, 18 parts of Radix Sophorae Flavescentiss, 10 parts of Cortex Phellodendris.
Embodiment 3
A kind of medicine for the treatment of verruca plana comprises the raw material of following weight portion in the medicine:
12 parts of 45 parts of Radix Isatidis, 20 parts of Radix Arnebiae (Radix Lithospermi)s, 40 parts of Herba Taraxaci, 30 parts of Rhizoma Cyperis, 15 parts of Radix Paeoniae Rubra, 30 parts of the Radixs Astragali, 24 parts of Radix Sophorae Tonkinensiss, 30 parts of Semen Coiciss, 20 parts of Herba Equiseties Hiemalis, 30 parts of Folium Isatidiss, 45 parts of Flos Loniceraes, Radix Sophorae Flavescentis 20g part, Cortex Phellodendri.
More than the preparation method of each embodiment Chinese medicine, may further comprise the steps:
A, take by weighing various raw materials according to required weight portion;
B, the various raw materials that will take by weighing are put into medicinal cupping, add water 500-600 part by weight, soak 20-40 minute;
C, very hot oven are fried boiling, and change slow fire again and fry in shallow oil 20-40 minute, leach medicinal liquid;
D, add water 350-450 part again in medicinal cupping, the very hot oven back slow fire that is fried boiling was fried in shallow oil 20-30 minute, the leaching medicinal liquid and with leaching first time medicinal liquid mixing.
Above embodiment Chinese medicine instructions of taking: respectively obey 150 milliliters on an empty stomach every day sooner or later, and two weeks were a course of treatment.The period in a medicine irritable food that avoids pungent food.
For showing the curative effect of medicine of the present invention, carried out clinical comparison.Use this prescription treatment verruca plana patient 187 examples over 5 years, wherein male 78 examples, women 109 examples, at minimum 14 years old of age, maximum 45 years old, the course of disease is the shortest 4 months, and was the longest 5 years, and 187 routine patients cure 92 examples altogether, account for 49.2%; Produce effects 62 examples account for 33.2%; Effective 20 examples account for 10.7%; Invalid 13 examples account for 7%; Total effective rate is 93%.
The formulation criterion of therapeutical effect is as follows:
Recovery from illness: the wart body all comes off, non-pigment calmness, nothing recurrence in 3 years;
Produce effects: wart body major part comes off, and part is left over pigmentation;
Effectively: minority wart body comes off, and most wart bodies still exist, and pruritus alleviates;
Invalid: the wart body does not have and comes off, and still has new wart to increase.
For showing the curative effect of Chinese medicine of the present invention, the spy provides clinical typical case history:
Case one: Zhao, woman, 22 years old, student.Face, the back of the hand play erythema, pimple was itched 1 year.Readme finds that the year before the appearance hatpin head of facial no obvious inducement greatly to the big pimple of foxtail millet grain, accompanies gargalesthesia, and is cumulative many, feeds through to the back of the hand, is that verruca plana is given oral medicine and failed to respond to any medical treatment to certain hospital admission once.Have a medical check-up: patient's forehead, buccal the back of the hand scatter the big normal color of the leather pimple of foxtail millet grain, and be circular, oval, surperficial flat multiangular, and part is beading arranges, and is diagnosed as verruca plana.The drug regimen side that uses the present invention to treat verruca plana is decocted in water for oral dose, and every day, potion serve on one month, and facial rash all comes off, and continues clothes after treatment first quarter moon and heals.
Case two: Liu, the man, 19 years old, because of facial, little the itching of the back of the hand pimpling companion were examined over two months.Once examined in certain township hospital and be " wart on the thousand ", oral ribavirin, external medicine cream is not quite clear, and erythra does not have change.Look into patient's forehead, near the eyes, buccal portion gathers the foxtail millet grain greatly to the big pimple of small rice grain, surperficial flat polygon, pale red, a little scratch, diagnosis: verruca plana.The patient requires treatment by Chinese herbs, is decocted in water for oral dose for Chinese medicine composition side, and this side's logotype February, verruca plana all comes off, and does not see that new erythra occurs.
Case three: Chen, woman 34 years old, the workman facial suffered from verruca plana 2 years, and once multi-treatment was not seen to be clearly better, and erythra has and increases trend year by year, introduces the here treatment through friend.Patient's forehead, near the eyes, the buccal normal color of the leather or the filbert pimple of gathering and to differ in size, surperficial flat polygon distributes in flakes, a little scratch is diagnosed as verruca plana.Be decocted in water for oral dose for Chinese medicine composition side, the two Zhou patient's scratchiness of taking medicine alleviate, and erythra continues to enlarge again, continue to take medicine deflorescence and fully recovering one month.
Case four: high so-and-so, man, 28 years old, secondary school teachers.The facial the back of the hand pimpling companion of patient gargalesthesia is gone to a doctor half a year.Have a medical check-up: the hatpin head is scattered greatly to the normal color of the leather pimple of small rice grain size in patient's two temples, buccal portion, both hands back, and the surface is flat, and polygon does not merge, and part becomes beading to arrange, a little scratch, diagnosis: verruca plana.Be decocted in water for oral dose for Chinese medicine composition side, treat after one month, the state of an illness is clearly better, and the part erythra comes off, and does not have new erythra and occurs, and after taking medicine three months, erythra all disappears and heals, and recurrence was not seen in drug withdrawal in 2 years.
Having mutual synergism in the pharmaceutical formulation of the present invention between the various Chinese medicines, the caused verruca plana of parillomarvirus infections is had extraordinary curative effect, is a kind of Chinese medicine preparation safely and effectively.

Claims (2)

1. medicine for the treatment of verruca plana is characterized in that comprising in the described medicine raw material of following weight portion: 9~12 parts of 30~45 parts of Radix Isatidis, 15~20 parts of Radix Arnebiae (Radix Lithospermi)s, 30~40 parts of Herba Taraxaci, 20~30 parts of Rhizoma Cyperis, 10~15 parts of Radix Paeoniae Rubra, 20~30 parts of the Radixs Astragali, 15~24 parts of Radix Sophorae Tonkinensiss, 20~30 parts of Semen Coiciss, 15~20 parts of Herba Equiseties Hiemalis, 20~30 parts of Folium Isatidiss, 30~45 parts of Flos Loniceraes, Radix Sophorae Flavescentis 15~20g part, Cortex Phellodendri.
2. according to the described a kind of medicine for the treatment of verruca plana of claim 1, it is characterized in that the preparation method of described medicine, may further comprise the steps:
A, take by weighing various raw materials according to required weight portion;
B, the various raw materials that will take by weighing are put into medicinal cupping, add water 500-600 part by weight, soak 20-40 minute;
C, very hot oven are fried boiling, and change slow fire again and fry in shallow oil 20-40 minute, leach medicinal liquid;
D, add water 350-450 part again in medicinal cupping, the very hot oven back slow fire that is fried boiling was fried in shallow oil 20-30 minute, the leaching medicinal liquid and with leaching first time medicinal liquid mixing.
CN201110022078XA 2011-01-14 2011-01-14 Medicament for treating verruca plana and preparation method thereof Expired - Fee Related CN102085319B (en)

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CN102302638A (en) * 2011-08-13 2012-01-04 李为国 Traditional Chinese medicine (TCM) formula for treating flat wart
CN102698157A (en) * 2012-06-27 2012-10-03 杨万明 Medicine for treating flat wart and preparation method thereof
CN102716410A (en) * 2011-10-17 2012-10-10 冯静 Traditional Chinese medicine composition for treating verruca vulgaris
CN103386047A (en) * 2013-07-25 2013-11-13 李厚宽 Chinese medicine decoction for treating verruca plana
CN103585535A (en) * 2013-12-04 2014-02-19 李慧 Traditional Chinese medicine for treating verruca plana
CN103860955A (en) * 2014-03-07 2014-06-18 张家能 Traditional Chinese medicine combination for treating human papillomavirus infection and preparation method of traditional Chinese medicine combination
CN104435888A (en) * 2014-11-30 2015-03-25 顾蔷怡 Medicine for treating verruca plana and preparation method of medicine
CN104688995A (en) * 2015-01-27 2015-06-10 青岛市市立医院 Medicine for treatment of condyloma acuminate and preparation method thereof
CN105641546A (en) * 2014-11-25 2016-06-08 武汉鸿兴疆科技有限公司 Preparation method of oral traditional Chinese medicine for treatment of verruca plana
CN107802766A (en) * 2017-11-29 2018-03-16 罗田县人民医院 A kind of Chinese medicine composition for treating flat wart
CN109394994A (en) * 2018-12-29 2019-03-01 王玺 It is a kind of to treat anti-recurrence pharmaceutical composition of condyloma acuminatum and preparation method thereof
CN111298045A (en) * 2019-11-18 2020-06-19 赵艳君 External medicine for treating flat wart and preparation method thereof
CN114246926A (en) * 2022-01-10 2022-03-29 上海中医药大学附属岳阳中西医结合医院 External traditional Chinese medicine composition for treating skin warts and preparation method and application thereof

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Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102302638A (en) * 2011-08-13 2012-01-04 李为国 Traditional Chinese medicine (TCM) formula for treating flat wart
CN102716410A (en) * 2011-10-17 2012-10-10 冯静 Traditional Chinese medicine composition for treating verruca vulgaris
CN102698157A (en) * 2012-06-27 2012-10-03 杨万明 Medicine for treating flat wart and preparation method thereof
CN103386047A (en) * 2013-07-25 2013-11-13 李厚宽 Chinese medicine decoction for treating verruca plana
CN103585535A (en) * 2013-12-04 2014-02-19 李慧 Traditional Chinese medicine for treating verruca plana
CN103860955A (en) * 2014-03-07 2014-06-18 张家能 Traditional Chinese medicine combination for treating human papillomavirus infection and preparation method of traditional Chinese medicine combination
CN105641546A (en) * 2014-11-25 2016-06-08 武汉鸿兴疆科技有限公司 Preparation method of oral traditional Chinese medicine for treatment of verruca plana
CN104435888A (en) * 2014-11-30 2015-03-25 顾蔷怡 Medicine for treating verruca plana and preparation method of medicine
CN104688995A (en) * 2015-01-27 2015-06-10 青岛市市立医院 Medicine for treatment of condyloma acuminate and preparation method thereof
CN107802766A (en) * 2017-11-29 2018-03-16 罗田县人民医院 A kind of Chinese medicine composition for treating flat wart
CN109394994A (en) * 2018-12-29 2019-03-01 王玺 It is a kind of to treat anti-recurrence pharmaceutical composition of condyloma acuminatum and preparation method thereof
CN111298045A (en) * 2019-11-18 2020-06-19 赵艳君 External medicine for treating flat wart and preparation method thereof
CN114246926A (en) * 2022-01-10 2022-03-29 上海中医药大学附属岳阳中西医结合医院 External traditional Chinese medicine composition for treating skin warts and preparation method and application thereof

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