CN102071113B - Condensed multi-enzyme medical cleaning agent - Google Patents
Condensed multi-enzyme medical cleaning agent Download PDFInfo
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- CN102071113B CN102071113B CN 201110034505 CN201110034505A CN102071113B CN 102071113 B CN102071113 B CN 102071113B CN 201110034505 CN201110034505 CN 201110034505 CN 201110034505 A CN201110034505 A CN 201110034505A CN 102071113 B CN102071113 B CN 102071113B
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Abstract
The invention relates to a condensed multi-enzyme medical cleaning agent. The cleaning agent contains surfactants, a detergent auxiliary agent, a solubilizing agent, an enzymic preparation, a foam inhibitor and a preservative, wherein the surfactants are a non-ion surfactant and an anion surfactant. The cleaning agent comprises the following formula components in percentage by weight: 5 to 10 percent of alkoxyl fatty alcohol, 3 to 5 percent of alkyl polylucoside, 5 to 10 percent of alkanol polyether, 5 to 10 percent of sodium xylene sulfonate, 0.5 to 1.5 percent of sodium sulfate, 0.5 to 1 percent of calcium chloride, 2 to 4 percent of disodium ethylene diaminetetraacetate, 5 to 10 percent of hydrogenated castor oil, 6 to 12 percent of dipropylene glycol monomethyl ether, 5 to 10 percent of glycerol, 2 to 6 percent of proteinase, 1 to 5 percent of amylase, 1 to 5 percent of lipase, 0.5 to 1 percent of cellulase, 0.1 to 0.5 percent of methylparaben and propyl hydroxybenzoate preservative, 0.1 percent of essence, 0.1 percent of pigment and the balance of deionized water. Through the cleaning agent, all the biological residues adhered in and out of a medical apparatus can be quickly and effectively decomposed and cleaned and aluminum oxide playing a role in protection on the metal surface layer is not damaged.
Description
Technical field
The present invention relates to medical cleaning agent, relate in particular to a kind of multienzyme medical cleaning agent of efficient concentration, it is applicable to the manual cleaning of medicine equipment, automatic rinser and the Ultrasonic Cleaners etc. of medical institutions, and its range of application comprises surgery, internal medicine, tooth section, the employed instruments of Obstetric and Gynecologic Department and all kinds of endoscope such as gastroscope, intestines mirror and peritoneoscope etc.
Background technology
The instruments that the healthcare givers is used and endoscope can speckle with the large number of biological pollutent inevitably in the use procedure of the patient being performed the operation or checking, such as blood, albumen, mucosal tissue and fat etc.When these pollutents were withered, it adhered to viscous force and will greatly strengthen the medicine equipment top layer, thereby causes general common sanitising agent can't thoroughly decompose at short notice and remove these biological residues.Common sanitising agent is synthetic by tensio-active agent and inorganic reagent, and they can't effectively decompose its chemical composition decision the biology of the high adhesive forces such as albumen, fat and mucosal tissue and peel off, thereby the patient who uses to next bit brings Health hazard.
Biological enzyme such as proteolytic enzyme, amylase and lipase etc. can resolve into the material that is soluble in tensio-active agent with biological pollutants such as blood, albumen and fat by a kind of chemical reaction that is called hydrolysis, thereby with its thorough removing.
Effect is slow usually for employed medical multienzyme cleaning agent in the market, whole cleaning process reached about 10 minutes, its cleaning performance generally only is confined to remove biological residue, and can't effectively remove the inorganics that the metallic surface is adhered to, such as metal oxide, carbonate and sulfide etc.These material extended residuals can form film and the spot of white or grey in the metallic surface.Why common multienzyme cleaning agent can't remove these inorganicss is because it does not contain the chemical composition that can decompose these ions.
Summary of the invention
Task of the present invention provides a kind of concentrated multienzyme medical cleaning agent, it has solved the existing technical problem of above-mentioned prior art, can remove fast, effectively, up hill and dale all types of biological pollutants, such as blood, protein, cell debris, tissue, secretory product, mucus, saliva and ight soil, and metal oxide noted earlier (except the aluminum oxide), carbonate and sulfide etc.
Technical solution of the present invention is as follows:
A kind of concentrated multienzyme medical cleaning agent comprises tensio-active agent, washing auxiliary detergent and solubilizing agent, also comprises zymin, suds suppressor and sanitas;
Described tensio-active agent is nonionogenic tenside and anion surfactant.
The content of specific components in weight percent as follows of the prescription of described concentrated multienzyme medical cleaning agent:
Alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 5%～10%, alkyl poly glucoside 3%～5%, alkanol polyethers 5%～10%, sodium xylene sulfonate (SXS) 5%～10%, sodium sulfate 0.5%～1.5%, calcium chloride 0.5%～1%, disodium ethylene diamine tetraacetate (EDTA) 2%～4%, hydrogenated castor oil 5%～10%, dipropylene glycol monomethyl ether 6%～12%, glycerol 5%～10%, proteolytic enzyme 2%～6%, amylase 1%～5%, lipase 1%～5%, cellulase 0.5%～1%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.1%～0.5%, essence 0.1%, pigment 0.1%, surplus is deionized water.
The first embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 10%, alkyl poly glucoside 5%, alkanol polyethers 7.1%, sodium xylene sulfonate (SXS) 5%, sodium sulfate 1%, calcium chloride 1%, disodium ethylene diamine tetraacetate (EDTA) 4%, hydrogenated castor oil 5%, dipropylene glycol monomethyl ether 8%, glycerol 5%, proteolytic enzyme 5%, amylase 2 %, lipase 1%, cellulase 1%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.5%, essence 0.1%, pigment 0.1%, deionized water 39.2%.
The second embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 8%, alkyl poly glucoside 4%, alkanol polyethers 8%, sodium xylene sulfonate (SXS) 6%, sodium sulfate 0.5%, calcium chloride 0.6%, disodium ethylene diamine tetraacetate (EDTA) 3%, hydrogenated castor oil 8%, dipropylene glycol monomethyl ether 7%, glycerol 7%, protease 3 %, amylase 2 %, lipase 2%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 40%.
The 3rd embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 9%, alkyl poly glucoside 3%, alkanol polyethers 5%, sodium xylene sulfonate (SXS) 7%, sodium sulfate 1.2%, calcium chloride 0.8%, disodium ethylene diamine tetraacetate (EDTA) 2.5%, hydrogenated castor oil 6%, dipropylene glycol monomethyl ether 6%, glycerol 9%, proteolytic enzyme 2%, amylase 1%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 45.6%.
The 4th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 5%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate (SXS) 10%, sodium sulfate 1.5%, calcium chloride 0.5%, disodium ethylene diamine tetraacetate (EDTA) 3.5%, hydrogenated castor oil 5%, dipropylene glycol monomethyl ether 6%, glycerol 5%, proteolytic enzyme 6%, amylase 3%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.1%, essence 0.1%, pigment 0.1%, deionized water 43.7%.
The 5th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 6%, alkyl poly glucoside 5%, alkanol polyethers 10%, sodium xylene sulfonate (SXS) 5%, sodium sulfate 0.7%, calcium chloride 0.9%, disodium ethylene diamine tetraacetate (EDTA) 2%, hydrogenated castor oil 10%, dipropylene glycol monomethyl ether 6%, glycerol 10%, proteolytic enzyme 4%, amylase 5%, lipase 2%, cellulase 0.8%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 32.2%.
The 6th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 6%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate (SXS) 5%, sodium sulfate 0.8%, calcium chloride 0.7%, disodium ethylene diamine tetraacetate (EDTA) 2%, hydrogenated castor oil 7%, dipropylene glycol monomethyl ether 12%, glycerol 5%, protease 3 %, amylase 5%, lipase 5%, cellulase 0.8%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 38.3%.
The 7th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 8%, alkyl poly glucoside 4%, alkanol polyethers 8%, sodium xylene sulfonate (SXS) 6%, sodium sulfate 0.5%, calcium chloride 0.6%, disodium ethylene diamine tetraacetate (EDTA) 3%, hydrogenated castor oil 8%, dipropylene glycol monomethyl ether 7%, glycerol 7%, protease 3 %, amylase 2 %, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 41%.
The 8th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 9%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate (SXS) 7%, sodium sulfate 1.2%, calcium chloride 0.8%, disodium ethylene diamine tetraacetate (EDTA) 2.5%, hydrogenated castor oil 6%, dipropylene glycol monomethyl ether 6%, glycerol 9%, protease 3 %, amylase 1%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 43.6%.
Efficient concentration multienzyme medical cleaning agent of the present invention is synthetic by kinds of surface promoting agent and biological enzyme; can rapidly, effectively decompose and remove inside and outside all the accompanying biological residues of medicine equipment; such as blood, protein, cell debris, tissue, secretory product, mucus, saliva and ight soil etc.; it can not damage the aluminum oxide that aluminum products and stainless steel top layer are shielded, because do not contain oxyhydroxide or other chemical substance that can react with aluminium in its moiety.
Concentrated multienzyme medical cleaning agent of the present invention is after being diluted to working fluid, and its pH value presents complete neutrality, and all material is comprised that plastics, glass and each metalloid are all safe and reliable.Rinse product does not contain any oxyhydroxide, acid and corrosive organic solvent.
Medical cleaning agent of the present invention can need not pre-treatment all medicine equipments of Rapid Cleaning under (keep apparatus top layer moistening) and the hyperacoustic condition.During use clean-out system is diluted 100～300 times of working fluids.Generally, for instruments and the endoscope of common pollution, dilute 300 times, only need just can finish in 2～5 minutes the decomposition course of whole biological residue; For the serious pollution thing, can correspondingly Dilution ratio be reduced to 100 times, within the same short time, to reach identical cleaning performance.
Rinse product is diluted in presents as clear as crystal solution in the ordinary tap water, without any muddiness.In cleaning process, keep extremely low foam even foamless state, so this clean-out system is applicable to all automatic cyclic cleaning machine and Ultrasonic Cleaners always.
According to raw produce; raw products specification and characteristic, the employed raw material of efficient concentration multienzyme medical cleaning agent of the present invention is biodegradable, nontoxic, environmental sound, and the indices of working solution all meets environmental protection and healthy requirement after dilution.
Embodiment
A kind of concentrated multienzyme medical cleaning agent of the present invention mainly contains tensio-active agent, washing auxiliary detergent, solubilizing agent, zymin, suds suppressor and sanitas.Described tensio-active agent is nonionogenic tenside and anion surfactant.
Ionic surfactant pack is drawn together fatty alcohol-polyoxyethylene ether, polyoxyethylene carboxylate, polyoxyethylene alkylphenol ether, polyoxyethylene alkyl amine, polyoxy olefin-copolymerization tensio-active agent, how pure tensio-active agent, N-alkyl pyrrolidone, amine oxide, alkyl poly glucoside etc.Nonionogenic tenside is unionization in water, and its hydrophilic group mainly is to be made of the oxy radical of some amount (being generally ether and hydroxyl).These characteristics have determined that nonionogenic tenside is more superior than ionic surface active agent in some aspects just: owing to not being ionic condition in solution, stability is high; Be not subject to the impact that the strong electrolyte inorganic salt exist, be not subject to the impact of acid, alkali yet; Good with other type list surface-active agent compatibility, can compositely use; Preferably solubility property is all arranged in water and organic solvent; Because unionization in solution, therefore be difficult for occuring strong adsorption at general solid surface.
Anion surfactant comprises carboxylate salt, sulfonate, alkyl-sulphate and phosphate ester salt.
Washing auxiliary detergent itself does not have obvious washability, but being added on the washing soil removability that but can make tensio-active agent in the detergent formulation is improved.Washing auxiliary detergent divides inorganic and organic two large classes, inorganics such as tripoly phosphate sodium STPP, water glass, yellow soda ash, sodium sulfate etc.; Organism has disodium ethylene diamine tetraacetate, nitrilotriacetic acid salt, Trisodium Citrate, polyacrylic acid etc.Complicated interaction occurs between they and the surfactant molecule, and the result makes washing effect than using separately the tensio-active agent fashion, therefore this effect is also referred to as synergy.
Solubilizing agent is to improve various components solubleness in water in the washing composition.Solubilizing agent commonly used has industrial spirit, urea, Tween-60, toluenesulfonic acid sodium salt, cumene sodium sulfonate, polyoxyethylene glycol, Virahol, trolamine etc.They have the washing composition of making increases solubleness, reduces the effects such as solution relative density and reduction soltion viscosity in water.
Enzyme is biological catalyst.The enzyme that uses in the washing composition has proteolytic enzyme, lipase, amylase and cellulase etc.They all are lytic enzymes, can distinguish catalytic proteins, fat, starch and cellulosic hydrolysis, make the dirt macromole resolve into small molecules and are removed.
The content of specific components in weight percent as follows of the prescription of efficient concentration multienzyme medical cleaning agent of the present invention:
Alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 5%～10%, alkyl poly glucoside 3%～5%, alkanol polyethers 5%～10%, sodium xylene sulfonate (SXS) 5%～10%, sodium sulfate 0.5%～1.5%, calcium chloride 0.5%～1%, disodium ethylene diamine tetraacetate (EDTA) 2%～4%, hydrogenated castor oil 5%～10%, dipropylene glycol monomethyl ether 6%～12%, glycerol 5%～10%, proteolytic enzyme 2%～6%, amylase 1%～5%, lipase 1%～5%, cellulase 0.5%～1%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.1%～0.5%, essence 0.1%, pigment 0.1%, surplus is deionized water.
The first Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 10%, alkyl poly glucoside 5%, alkanol polyethers 7.1%, sodium xylene sulfonate (SXS) 5%, sodium sulfate 1%, calcium chloride 1%, disodium ethylene diamine tetraacetate (EDTA) 4%, hydrogenated castor oil 5%, dipropylene glycol monomethyl ether 8%, glycerol 5%, proteolytic enzyme 5%, amylase 2 %, lipase 1%, cellulase 1%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.5%, essence 0.1%, pigment 0.1%, deionized water 39.2%.
The second Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 8%, alkyl poly glucoside 4%, alkanol polyethers 8%, sodium xylene sulfonate (SXS) 6%, sodium sulfate 0.5%, calcium chloride 0.6%, disodium ethylene diamine tetraacetate (EDTA) 3%, hydrogenated castor oil 8%, dipropylene glycol monomethyl ether 7%, glycerol 7%, protease 3 %, amylase 2 %, lipase 2%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 40%.
The 3rd Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 9%, alkyl poly glucoside 3%, alkanol polyethers 5%, sodium xylene sulfonate (SXS) 7%, sodium sulfate 1.2%, calcium chloride 0.8%, disodium ethylene diamine tetraacetate (EDTA) 2.5%, hydrogenated castor oil 6%, dipropylene glycol monomethyl ether 6%, glycerol 9%, proteolytic enzyme 2%, amylase 1%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 45.6%.
The 4th Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 5%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate (SXS) 10%, sodium sulfate 1.5%, calcium chloride 0.5%, disodium ethylene diamine tetraacetate (EDTA) 3.5%, hydrogenated castor oil 5%, dipropylene glycol monomethyl ether 6%, glycerol 5%, proteolytic enzyme 6%, amylase 3%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.1%, essence 0.1%, pigment 0.1%, deionized water 43.7%.
The 5th Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 6%, alkyl poly glucoside 5%, alkanol polyethers 10%, sodium xylene sulfonate (SXS) 5%, sodium sulfate 0.7%, calcium chloride 0.9%, disodium ethylene diamine tetraacetate (EDTA) 2%, hydrogenated castor oil 10%, dipropylene glycol monomethyl ether 6%, glycerol 10%, proteolytic enzyme 4%, amylase 5%, lipase 2%, cellulase 0.8%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 32.2%.
The 6th Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 6%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate (SXS) 5%, sodium sulfate 0.8%, calcium chloride 0.7%, disodium ethylene diamine tetraacetate (EDTA) 2%, hydrogenated castor oil 7%, dipropylene glycol monomethyl ether 12%, glycerol 5%, protease 3 %, amylase 5%, lipase 5%, cellulase 0.8%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 38.3%.
The 7th Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 8%, alkyl poly glucoside 4%, alkanol polyethers 8%, sodium xylene sulfonate (SXS) 6%, sodium sulfate 0.5%, calcium chloride 0.6%, disodium ethylene diamine tetraacetate (EDTA) 3%, hydrogenated castor oil 8%, dipropylene glycol monomethyl ether 7%, glycerol 7%, protease 3 %, amylase 2 %, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 41%.
The 8th Example formulations by concentrated multienzyme medical cleaning agent prescription making of the present invention, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) (LS45) 9%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate (SXS) 7%, sodium sulfate 1.2%, calcium chloride 0.8%, disodium ethylene diamine tetraacetate (EDTA) 2.5%, hydrogenated castor oil 6%, dipropylene glycol monomethyl ether 6%, glycerol 9%, protease 3 %, amylase 1%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+oxybenzene the third fat sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 43.6%.
Concentrated multienzyme medical cleaning agent of the present invention has carried out following series of experiments in preparation process.
1, product experiment
(1) low bubble experiment:
Use the 40KHz Ultrasonic Cleaners, add 6 liters of ordinary tap water, according to the 1:300 Dilution ratio, add 20 milliliters of concentrated multienzyme medical cleaning agents, formation work dissolving.External recycle pump flows in order to liquid circulation.Ultrasonic frequency is transferred to 40KHz, pump flow is set as 50L/ minute, recycle pump water refluxing opening is apart from 10 centimetres of fluid surfaces, solution temperature is 15 ℃, move 30 minutes, experimental result be foam height less than 10 millimeters, the foaming scope only is confined to recycle pump recirculation water drop point radius 5 centimeters, when recirculation water filling liquid surface, the foam of generation disappeared in 1～3 second.
Get similar from the low bubble of external import brand medical cleaning agent, under above-mentioned the same terms, carry out identical experiment, experimental result is that foam height is less than 10 millimeters, the foaming scope is confined to recycle pump recirculation water drop point radius 20 centimeters, when recirculation water filling liquid surface, the foam of generation disappeared in 3～10 seconds.
This experimental results show that: concentrated multienzyme medical cleaning agent of the present invention presents low bubble to still state in working order the time, belongs to low bubble clean-out system, and its low bubble performance meets and exceeds the like product of external import.
(2) cloud point experiment:
This concentrated multienzyme medical cleaning agent and tap water are mixed with respectively each 300 milliliters of working solution according to 1:100 and 1:300 ratio, and be positioned on the infrared heating oven, setting process furnace power is 600W, use simultaneously at any time recording solution temperature of mercurythermometer, Range of measuring temp is 10 ℃～60 ℃.Result's demonstration, from 10 ℃～60 ℃ uphill process, the working solution of two kinds of concentration remains as clear as crystal state at solution temperature.
Get similar hanging down from external import brand and steep medical cleaning agent, under above-mentioned the same terms, carry out identical experiment, result's demonstration, from 10 ℃～60 ℃ uphill process, the working solution of two kinds of concentration also remains as clear as crystal state at solution temperature.
This experimental results show that: concentrated multienzyme medical cleaning agent of the present invention can not cause working solution turbid phenomenon to occur in actual application, and the cloud point performance reaches the like product of external import.
(3) cleaning performance experiment:
This experiment adopts the withered blood of cleaning human body to verify that this concentrated multienzyme medical cleaning agent is to the cleaning performance of biological pollutant.
Get 10 of brand-new microscope special glass slide glasss, its specification is 76.2 millimeters of length, 25.4 millimeters of width, 1.2 millimeters of thickness.
Get 10 of brand-new stainless steel metal operating forcepses.
Extract same human vein blood, instillation human body blood is 1 milliliter on every slide glass, evenly is applied in slide surface; Every operating forceps is immersed 5 centimetres of degree of depth in the container of collecting blood, immersed 1 minute, take out.
Place in the ventilation and spend the night (more than 10 hours) scribbling the slide glass of blood of human body and operating forceps, make it fully withered.This is limiting case in the operation of actual medical mechanism or the splanchnoscopy, its objective is for check multienzyme cleaning agent cleaning performance.In actual clinical work, after usually performing the operation or having checked, all apparatuses of being infected with biological pollutant will clean immediately at once, and the medicine equipment flushing procedure does not allow that placing spends the night causes that pollutent is withered to be condensed.
Use respectively concentrated multienzyme medical cleaning agent of the present invention and similar import medical cleaning agent, prepare each 5 glasss of 300 milliliters of working solutions with tap water according to the 1:300 Dilution ratio.Under 10 ℃, 20 ℃, 30 ℃, 40 ℃, 50 ℃ working solution temperature, in every glass of working solution, put into slide glass and an operating forceps that a slice scribbles blood of human body respectively, observe blood removing speed and effect.
Experimental result shows: in the time of 10 ℃, this concentrated multienzyme medical cleaning agent began to decompose blood in 20 seconds, thoroughly removed the blood on the slide glass in 3 minutes, and thorough the removing on the operating forceps adhered to blood in 10 minutes; The similar medical cleaning agent of import began to decompose blood in 30 seconds, thoroughly removed the blood on the slide glass, thoroughly adhered to blood on the removing operating forceps in 12 minutes in 5 minutes.
Experimental result shows: in the time of 20 ℃, this concentrated multienzyme medical cleaning agent began to decompose blood in 15 seconds, thoroughly removed the blood on the slide glass in 2 minutes 40 seconds, and thorough the removing on the operating forceps adhered to blood in 9 minutes 30 seconds; The similar medical cleaning agent of import began to decompose blood in 25 seconds, thoroughly removed the blood on the slide glass, thoroughly adhered to blood on the removing operating forceps in 11 minutes in 4 minutes 30 seconds.
Experimental result shows: in the time of 30 ℃, this concentrated multienzyme medical cleaning agent began to decompose blood in 12 seconds, thoroughly removed the blood on the slide glass in 2 minutes 20 seconds, and thorough the removing on the operating forceps adhered to blood in 8 minutes; The similar medical cleaning agent of import began to decompose blood in 20 seconds, thoroughly removed the blood on the slide glass, thoroughly adhered to blood on the removing operating forceps in 9 minutes in 3 minutes 30 seconds.
Experimental result shows: in the time of 40 ℃, this concentrated multienzyme medical cleaning agent began to decompose blood in 9 seconds, thoroughly removed the blood on the slide glass in 2 minutes, and thorough the removing on the operating forceps adhered to blood in 7 minutes; The similar medical cleaning agent of import began to decompose blood in 10 seconds, thoroughly removed the blood on the slide glass, thoroughly adhered to blood on the removing operating forceps in 7 minutes 30 seconds in 2 minutes 20 seconds.
Experimental result shows: in the time of 50 ℃, this concentrated multienzyme medical cleaning agent began to decompose blood in 5 seconds, thoroughly removed the blood on the slide glass in 1 minute 30 seconds, and thorough the removing on the operating forceps adhered to blood in 5 minutes; The similar medical cleaning agent of import began to decompose blood in 5 seconds, thoroughly removed the blood on the slide glass, thoroughly adhered to blood on the removing operating forceps in 5 minutes in 1 minute 40 seconds.
Owing to containing protein and fat in the blood of human body, they are the main component in the biological pollutant of being infected with behind general operation or the endoscope, and are therefore representative to the cleaning performance of blood of human body.Above-mentionedly experiment showed, that concentrated multienzyme medical cleaning agent of the present invention can decompose the removing biological pollutant at short notice under the withered extreme condition more than 10 hours of blood, its cleaning performance meets and exceeds the cleaning performance of external import like product.
In addition, concentrated multienzyme medical cleaning agent of the present invention is sent into provincial front three hospital operating room and Endoscopy Room carry out the actual clinical experiment, the result shows: this concentrated multienzyme medical cleaning agent is after being mixed with working solution after the dilution, solution is as clear as crystal, without muddy, low bubble can be removed medicine equipment top layer biological pollutant in 1～5 minute, cleaning speed and cleaning performance all reach the same kind of products at abroad level.
Certainly, those skilled in the art in the art will be appreciated that, above-mentioned all embodiment illustrate the present invention, and be not as limitation of the invention, as long as in connotation scope of the present invention, all will drop in the scope of claim of the present invention conversion, the modification of above-described embodiment.
Claims (9)
1. a concentrated multienzyme medical cleaning agent comprises tensio-active agent, washing auxiliary detergent and solubilizing agent, it is characterized in that, also comprises zymin, suds suppressor and sanitas;
Described tensio-active agent is nonionogenic tenside and anion surfactant;
The content of specific components in weight percent as follows of the prescription of described concentrated multienzyme medical cleaning agent:
Alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 5%～10%, alkyl poly glucoside 3%～5%, alkanol polyethers 5%～10%, sodium xylene sulfonate SXS5%～10%, sodium sulfate 0.5%～1.5%, calcium chloride 0.5%～1%, disodium ethylene diamine tetraacetate 2%～4%, hydrogenated castor oil 5%～10%, dipropylene glycol monomethyl ether 6%～12%, glycerol 5%～10%, proteolytic enzyme 2%～6%, amylase 1%～5%, lipase 1%～5%, cellulase 0.5%～1%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.1%～0.5%, essence 0.1%, pigment 0.1%, surplus is deionized water.
2. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the first embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 10%, alkyl poly glucoside 5%, alkanol polyethers 7.1%, sodium xylene sulfonate SXS5%, sodium sulfate 1%, calcium chloride 1%, disodium ethylene diamine tetraacetate 4%, hydrogenated castor oil 5%, dipropylene glycol monomethyl ether 8%, glycerol 5%, proteolytic enzyme 5%, amylase 2 %, lipase 1%, cellulase 1%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.5%, essence 0.1%, pigment 0.1%, deionized water 39.2%.
3. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the second embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 8%, alkyl poly glucoside 4%, alkanol polyethers 8%, sodium xylene sulfonate SXS6%, sodium sulfate 0.5%, calcium chloride 0.6%, disodium ethylene diamine tetraacetate 3%, hydrogenated castor oil 8%, dipropylene glycol monomethyl ether 7%, glycerol 7%, protease 3 %, amylase 2 %, lipase 2%, cellulase 0.5%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 40%.
4. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the 3rd embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 9%, alkyl poly glucoside 3%, alkanol polyethers 5%, sodium xylene sulfonate SXS7%, sodium sulfate 1.2%, calcium chloride 0.8%, disodium ethylene diamine tetraacetate 2.5%, hydrogenated castor oil 6%, dipropylene glycol monomethyl ether 6%, glycerol 9%, proteolytic enzyme 2%, amylase 1%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 45.6%.
5. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the 4th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 5%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate SXS10%, sodium sulfate 1.5%, calcium chloride 0.5%, disodium ethylene diamine tetraacetate 3.5%, hydrogenated castor oil 5%, dipropylene glycol monomethyl ether 6%, glycerol 5%, proteolytic enzyme 6%, amylase 3%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.1%, essence 0.1%, pigment 0.1%, deionized water 43.7%.
6. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the 5th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 6%, alkyl poly glucoside 5%, alkanol polyethers 10%, sodium xylene sulfonate SXS5%, sodium sulfate 0.7%, calcium chloride 0.9%, disodium ethylene diamine tetraacetate 2%, hydrogenated castor oil 10%, dipropylene glycol monomethyl ether 6%, glycerol 10%, proteolytic enzyme 4%, amylase 5%, lipase 2%, cellulase 0.8%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 32.2%.
7. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the 6th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 6%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate SXS5%, sodium sulfate 0.8%, calcium chloride 0.7%, disodium ethylene diamine tetraacetate 2%, hydrogenated castor oil 7%, dipropylene glycol monomethyl ether 12%, glycerol 5%, protease 3 %, amylase 5%, lipase 5%, cellulase 0.8%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 38.3%.
8. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the 7th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 8%, alkyl poly glucoside 4%, alkanol polyethers 8%, sodium xylene sulfonate SXS6%, sodium sulfate 0.5%, calcium chloride 0.6%, disodium ethylene diamine tetraacetate 3%, hydrogenated castor oil 8%, dipropylene glycol monomethyl ether 7%, glycerol 7%, protease 3 %, amylase 2 %, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 41%.
9. concentrated multienzyme medical cleaning agent according to claim 1 is characterized in that, the 8th embodiment of described concentrated multienzyme medical cleaning agent prescription, its component concentration is by weight percentage: alkoxyl group Fatty Alcohol(C12-C14 and C12-C18) 9%, alkyl poly glucoside 3%, alkanol polyethers 6%, sodium xylene sulfonate SXS7%, sodium sulfate 1.2%, calcium chloride 0.8%, disodium ethylene diamine tetraacetate 2.5%, hydrogenated castor oil 6%, dipropylene glycol monomethyl ether 6%, glycerol 9%, protease 3 %, amylase 1%, lipase 1%, cellulase 0.5%, methyl hydroxybenzoate+Propyl Hydroxybenzoate sanitas 0.2%, essence 0.1%, pigment 0.1%, deionized water 43.6%.
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| DE102014003484A1 (en) * | 2014-03-14 | 2015-09-17 | Bode Chemie Gmbh | Cleaner for inanimate surfaces with special effectiveness against mucus, secretions, blood and biofilms |
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| CN106833927A (en) * | 2016-12-09 | 2017-06-13 | 山东新华医疗器械股份有限公司 | Medical scope biomembrane remover and preparation method thereof |
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| AR061906A1 (en) * | 2006-07-18 | 2008-10-01 | Novapharm Res Australia | LOW FOAM CLEANER |
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| CN101077999A (en) * | 2006-05-25 | 2007-11-28 | 常锋 | Method for preparing multienzyme cleaning agent for medical purpose |
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