CN102068607B - Chinese medicinal preparation for treating leukopenia and stomach upset caused by radiotherapy and chemotherapy - Google Patents

Chinese medicinal preparation for treating leukopenia and stomach upset caused by radiotherapy and chemotherapy Download PDF

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Publication number
CN102068607B
CN102068607B CN2011100040128A CN201110004012A CN102068607B CN 102068607 B CN102068607 B CN 102068607B CN 2011100040128 A CN2011100040128 A CN 2011100040128A CN 201110004012 A CN201110004012 A CN 201110004012A CN 102068607 B CN102068607 B CN 102068607B
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chemotherapy
chinese medicine
radiotherapy
treatment
caused
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CN102068607A (en
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郝少君
吕宏迪
王希东
李军
刘晓斌
杨凯
张中华
龙新生
李献玉
张正臣
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No371 Hospital Of Pla
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No371 Hospital Of Pla
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Abstract

The invention discloses a Chinese medicinal preparation for treating leukopenia and stomach upset caused by radiotherapy and chemotherapy. The key points of the technical scheme are that the Chinese medicinal preparation for treating the leukopenia and stomach upset caused by radiotherapy and chemotherapy is characterized by being prepared by the following steps of: (1) selecting ginseng, flatstem milkvetch seed, Chinese angelica, pangolin scales, figwort root, and dwarf lilyturf tuber; (2) adding water into the Chinese medicaments and decocting, and concentrating decoction until the decoction is syrup-like concentrated solution with the density of between 1.15 and 1.30; and (3) adding 95 percent ethanol with the stirring at room temperature, standing a liquid medicament for more than 24 hours when the ethanol content of the whole liquid medicament reaches 60 percent, and placing supernatant into an extractor and heating until no ethanol smell is generated to obtain the preparation. The Chinese medicinal preparation has good using effect, and can effectively relieve the symptoms such as stomach upset and the like caused by radiotherapy and chemotherapy.

Description

Treatment by put, the Chinese medicine preparation of leukopenia caused by cancer chemotherapy and gastrointestinal upset
Technical field:
The present invention relates to Chinese medicine, particularly a kind of treatment by put, the Chinese medicine preparation of leukopenia caused by cancer chemotherapy and gastrointestinal upset.
Background technology:
The treatment of tumour patient especially in chemotherapy, radiotherapy process, is easy to make patient's leukopenia and gastrointestinal tract to occur uncomfortable; Influence patient's diet and successive treatment; And make patient suffer more misery, though and now many to the medicine of leukopenia that causes by chemotherapy, radiotherapy and gastrointestinal upset disease, all be Western medicine mostly; Untoward reaction is many, is unfavorable for patient's treatment and recovery.
Summary of the invention:
The purpose of this invention is to provide and a kind ofly can effectively alleviate the leukopenia that causes by chemotherapy, radiotherapy and the Chinese medicine preparation of gastrointestinal upset.Technical scheme of the present invention is, treatment by put, the Chinese medicine preparation of leukopenia caused by cancer chemotherapy and gastrointestinal upset, it is characterized in that: Radix Ginseng 150-250g is chosen in (1); SHAWANZI 200-400g, Radix Angelicae Sinensis 150-250g, Squama Manis 50-150g; Radix Scrophulariae 150-250g, Radix Ophiopogonis 100-300g; (2) get above-mentioned Chinese medicine decocte with water; Decoction liquor is concentrated into melicera concentrated solution; Concentrated solution density is 1.15-1.30, adds 95% ethanol limit edged during (3) room temperature and stirs, when the ethanol content of whole medicinal liquid reaches 60%; Medicinal liquid was placed more than 24 hours, got supernatant and put to be heated in the extractor and do not have the alcohol flavor and promptly get preparation according to the invention.The 15-20 of the gross mass that the middle amount of water of said step (2) is the selected every Chinese medicine of step (1) doubly.In the said step (3) alcoholic acid addition be concentrated juice cumulative volume 1.2-2 doubly.Result of use of the present invention is good, can effectively alleviate the symptoms such as gastrointestinal upset that caused by chemotherapy, radiotherapy.
The specific embodiment:
Describe specific embodiment of the present invention in detail,
Embodiment 1:
Choose Radix Ginseng 150g, SHAWANZI 200g, Radix Angelicae Sinensis 200g, Squama Manis 50g, Radix Scrophulariae 150g, Radix Ophiopogonis 100g; (2) water of 8 times of quality of adding Chinese medicine gross weight decocts in above-mentioned Chinese medicine, after about 40 minutes, medical filtration is gone out; The water that adds 6 times of quality of last medicinal residues gross weight in the remaining medicinal residues decocts, and after about 40 minutes, medical filtration is gone out; The water that adds 5 times of quality of last medicinal residues gross weight in the remaining medicinal residues decocts, and after about 40 minutes, the medicinal liquid that medicinal liquid and front are taken advantage of out is gathered together and becomes concentrated solution; Concentrated solution density is that the 95% ethanol limit edged that 1.15 (3) room temperatures add 1.2 times of volumes of concentrated solution stirs, when the ethanol content of whole medicinal liquid reaches 60%, after medicinal liquid placed 24 hours; Supernatant in the middle of the taking liquid; Said supernatant is a liquid of removing medicinal residues, places extractor, and reheat does not promptly get preparation according to the invention to there being the alcohol flavor.
Embodiment 2:
Choose Radix Ginseng 200g, SHAWANZI 300g, Radix Angelicae Sinensis 150g, Squama Manis 100g, Radix Scrophulariae 250g, Radix Ophiopogonis 200g; (2) water of 6 times of quality of adding Chinese medicine gross weight decocts in above-mentioned Chinese medicine, after about 40 minutes, medical filtration is gone out; The water that adds 5 times of quality of last medicinal residues gross weight in the remaining medicinal residues decocts, and after about 40 minutes, medical filtration is gone out; The water that adds 4 times of quality of last medicinal residues gross weight in the remaining medicinal residues decocts, and after about 40 minutes, the medicinal liquid that medicinal liquid and front are taken advantage of out is gathered together and becomes concentrated solution; Concentrated solution density is the 95% ethanol limit edged stirring that 1.25 (3) room temperatures add 1.5 times of volumes of concentrated solution; When the ethanol content of whole medicinal liquid reaches 60%, after medicinal liquid placed 24 hours, the supernatant in the middle of the taking liquid; Said supernatant is a liquid of removing medicinal residues, places the extractor reheat promptly not get preparation according to the invention to there being the alcohol flavor.
Embodiment 3:
Choose Radix Ginseng 250g, SHAWANZI 400g, Radix Angelicae Sinensis 250g, Squama Manis 150g, Radix Scrophulariae 200g, Radix Ophiopogonis 300g; (2) water of 9 times of quality of adding Chinese medicine gross weight decocts in above-mentioned Chinese medicine, after about 40 minutes, medical filtration is gone out; The water that adds 6 times of quality of last medicinal residues gross weight in the remaining medicinal residues decocts, and after about 40 minutes, medical filtration is gone out; The water that adds 5 times of quality of last medicinal residues gross weight in the remaining medicinal residues decocts, and after about 40 minutes, the medicinal liquid that medicinal liquid and front are taken advantage of out is gathered together and becomes concentrated solution; Concentrated solution density is 1.30, and the 95% ethanol limit edged that (3) room temperature adds 2 times of volumes of concentrated solution stirs, when the ethanol content of whole medicinal liquid reaches 60%; After medicinal liquid placed 24 hours, the supernatant in the middle of the taking liquid, said supernatant is a liquid of removing medicinal residues; Place extractor, reheat does not promptly get preparation according to the invention to there being the alcohol flavor.
Actual therapeutic case of the present invention:
1. Zhang Yun, the woman, 59 years old, Xinxiang City 103 producers belonged to institute, phone 15203738721; The patient lower abdominal pain occurs in July, 2009, and menorrhagia once was diagnosed as carcinoma of corpus uteri to First People's Hospital, Xinxiang City; Give FD scheme chemotherapy, the here prescription on individual diagnosis of coming on August 1st, 2009, card is seen: shallow complexion, anorexia; Vomiting is felt sick, pale tongue, the weary less Tianjin of tongue, deep-thready pulse.Diagnosis: after the uterus carcinoma chemotherapy-anemia (QI and blood deficiency).Give the present invention in the treatment: a 20ml, cooperate nutritious food, every day three times, two months is a course of treatment, and after the course of treatment, patient's diet improves, and has rosy cheeks, and vomiting alleviates, and detects each item index, has reached clinical improvement.
2. Zhang Huarui, the man, 65 years old, Xinxiang City's cotton spinning company limited, phone 13837330618, in cough, chest pain, deficiency of QI with disinclination to talk after the inspection CT, attaches institute at Zheng Dayi and carries out biological tissue and learn inspection, is diagnosed as pulmonary carcinoma-mediastinal lymph node metastasis; 2 weeks behind the row CBP scheme chemotherapy, the here further consultation of coming on February 18th, 2010, card is seen: the lazy speech of breathing hard, health is become thin, and vomiting is felt sick, pale tongue, tongue stripping, thready and weak pulse; Diagnosis: behind the lung cancer chemotherapy-anemia (QI and blood deficiency).Give the present invention in the treatment: a 20ml, cooperate nutritious food, every day three times, two months is a course of treatment, and after the course of treatment, patient's diet improves, and it is red that complexion is changeed, and vomiting alleviates, and detects each item index, has arrived clinical improvement.
3. money clear and bright light, the man, 61 years old, Lin County retired employees of power supply administration, phone 13603757802, the patient spiritlessness and weakness occurs in November, 2008, dysphagia, retrosternal pain, loss of appetite, black stool.Come my institute went to a doctor on February 9th, 2009, through gastroscope and biopsy inspection, was diagnosed as the esophageal carcinoma, gave demonstrate,prove after the COT chemotherapy to see: obstinately vomit dysphagia, retrosternal pain, loss of appetite, black stool.Pale tongue, less fur, deep-slow pulse.Diagnosis: after the colon cancer chemotherapy-anemia (QI and blood deficiency).Give the present invention in the treatment: a 20ml, cooperates ondansetron to reach intramuscular injection once a day at every day three times; Two months is a course of treatment, and after the course of treatment, patient's diet improves, and complexion takes a turn for the better; Vomiting disappears, and detects each item index, has reached clinical improvement.
4. rowland is true, woman, 81 years old, Xinxiang City's nursing house, phone 15203938709; The patient lower abdominal pain occurs in August, 2009, occurs colporrhagia once more, and once central hospital was diagnosed as ovarian cancer to the Xinxiang City; Give docetaxel and add the hormone scheme chemotherapy, my the institute's prescription on individual diagnosis of coming on August 1st, 2009, card is seen: shallow complexion, health is become thin; Vomiting is felt sick, and body of the tongue is white, no fur, deep-thready pulse.Diagnosis: behind the chemotherapy in ovarian cancer-anemia (QI and blood deficiency).Give the present invention in the treatment: a 20ml, cooperate nutritious food, every day three times, cooperating erythropoietin and granulocyte colony-stimulating factor two months was a course of treatment; After the course of treatment, patient's diet improves, and has rosy cheeks; Vomiting alleviates, and detects each item index, has reached clinical improvement.
Result of use of the present invention is good, can effectively alleviate the symptoms such as gastrointestinal upset that caused by chemotherapy, radiotherapy.

Claims (3)

  1. Treatment by put, the Chinese medicine preparation of leukopenia caused by cancer chemotherapy and gastrointestinal upset, it is characterized in that: Radix Ginseng 150-250g is chosen in (1), Semen Astragali Complanati 200-400g, Radix Angelicae Sinensis 150-250g, Squama Manis 50-150g, Radix Scrophulariae 150-250g, Radix Ophiopogonis 100-300g; (2) get above-mentioned Chinese medicine decocte with water; Decoction liquor is concentrated into melicera concentrated solution; Concentrated solution density is 1.15-1.30, adds 95% ethanol limit edged during (3) room temperature and stirs, when the ethanol content of whole medicinal liquid reaches 60%; Medicinal liquid was placed more than 24 hours, got supernatant and put to be heated in the extractor and do not have the alcohol flavor and promptly accomplish preparation.
  2. 2. treatment as claimed in claim 1 by put, the Chinese medicine preparation of leukopenia caused by cancer chemotherapy and gastrointestinal upset, it is characterized in that: in the said step (2) amount of water be the selected every Chinese medicine of step (1) gross mass 15-20 doubly.
  3. 3. treatment as claimed in claim 1 by put, the Chinese medicine preparation of leukopenia caused by cancer chemotherapy and gastrointestinal upset, it is characterized in that: in the said step (3) alcoholic acid addition be concentrated juice cumulative volume 1.2-2 doubly.
CN2011100040128A 2011-01-05 2011-01-05 Chinese medicinal preparation for treating leukopenia and stomach upset caused by radiotherapy and chemotherapy Expired - Fee Related CN102068607B (en)

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CN103405632B (en) * 2013-07-29 2015-06-17 中国人民解放军济南军区联勤部药品仪器检验所 Oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla, preparation method thereof, and detection method of quality standard
CN105125846A (en) * 2015-03-02 2015-12-09 中国人民解放军第三七一医院 Oral liquid for treating side effects of chemoradiotherapy and preparation method thereof
CN104784584A (en) * 2015-04-27 2015-07-22 刘晓红 Herbal diet for inhibiting radiotherapy gastrointestinal reaction and preparation method
CN106729498A (en) * 2016-11-22 2017-05-31 安徽省纽斯康生物工程有限公司 A kind of albumen powder eaten after chemicotherapy and preparation method thereof

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CN101450189B (en) * 2008-12-19 2011-01-26 杨洪英 Medicine for curing angiocardiopathy and cerebrovascular disease and its preparing method

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