CN102068571A - Medicinal composition for treating urinary tract inflammation and preparation method thereof - Google Patents
Medicinal composition for treating urinary tract inflammation and preparation method thereof Download PDFInfo
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- CN102068571A CN102068571A CN2010106058120A CN201010605812A CN102068571A CN 102068571 A CN102068571 A CN 102068571A CN 2010106058120 A CN2010106058120 A CN 2010106058120A CN 201010605812 A CN201010605812 A CN 201010605812A CN 102068571 A CN102068571 A CN 102068571A
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Abstract
The invention relates to a medicinal composition for treating urinary tract inflammation and a preparation method thereof. The medicinal composition is prepared from the following Chinese medicinal raw materials: astragalus, alisma orientale, Indian buead, epimedium, medlar, pink herb, plantain herb, longhairy antenoron herb and the like by using the basic theory of traditional Chinese medical science, has the effects of tonifying kidney and qi, clearing heat and promoting diuresis and inducing diuresis for treating strangurtia, is used for treating the urinary tract inflammation of frequent micturition, urgent urination and odynuria which are caused by kidney deficiency and damp and heat, and has an obvious curative effect by years of clinical application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of the urinary tract inflammation, more specifically say so a kind of have tonify Qi of the kidney, the Chinese medicine composition of the treatment urinary tract inflammation of the effect of clearing away heat-damp and promoting diuresis, inducing diuresis for treating stranguria syndrome and preparation method thereof.
Background technology
The urinary tract inflammation is a kind of comparatively common disease.In the outpatient service first visit, account for 2%～3.8% based on urinary tract symptom.In lineup group's generaI investigation of China, the incidence rate of urinary tract inflammation infection is 2.31%.Material Takeoff according to the Europe dialysis and the center of transplanting in the chronic renal failure patient, accounts for 20% by what chronic pyelonephritis caused.The women once suffered from urinary tract infection person in a certain period in all one's life about 10%～20%, and it is about 6% that the adult women took place in 1 year by Symptomatic urinary tract infection person, with the married woman of childbearing age for seeing at most.
Doctor trained in Western medicine is thought, the urinary tract inflammation mainly is the Urinary system inflammation that is caused by bacterial infection, any pathogenic bacterium are invaded urinary tract all can cause urinary tract infection, but the most common pathogenic bacterium are intestinal gram negative bacilli, wherein bacillus coli more sees, accounts for 80～90% of acute urinary tract infection, antibacterial invade urinary system can by up, blood is capable, lymph road and 4 approach of direct extension, more than infection is the most common, and hematogenous infection takes second place.The factor relevant with morbidity also has the urinary tract infraction except that the antibacterial factor, the destruction of VUR, immunoreation, women's predisposing factor, local damage and defense mechanism and organism metabolism are unusual etc.Its main pathology is changed to mucous hyperemia, edema and a large amount of neutrophil infiltration, enters up expansion and falls ill.
The traditional Chinese medical science thinks that urinary tract infection is stranguria, and its pathogeny is: 1. damp-heat in the urinary bladder: damp-heat accumulation is in bladder, disturbance in functioning of QI, disturbance in water passage; 2. deficiency of spleen and stomach: spleen kidney deficiency worn with age, or because of quench one's thirst, disease such as edema injures taste, or reason consumption impairment of the spleen kidney such as overfatigue, or the pyretic stranguria disease prolongs and with the passing of time consumes impairment of QI and impairment of YIN, all can cause deficiency of spleen and stomach, dysfunction of the spleen in transportation, deficiency of QI in middle-JIAO, instability of kidney QI, bladder qi dysfunction; 3. kidney qi loss: with the passing of time gonorrhea injures kidney yin, the deficiency of YIN and damp and hot souvenir, and functioning of bladder is unfavorable.So this sick base therapy rule is a heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome.
Medicine of the present invention is guidance with the Chinese medical theory, is the Therapeutic Principle with " tonify Qi of the kidney, heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome ", through systematic study, science compatibility, has developed a kind of pure Chinese medicinal preparation for the treatment of the urinary tract inflammation.
Summary of the invention
Purpose of the present invention just provides a kind of pharmaceutical composition for the treatment of the urinary tract inflammation and preparation method thereof, this pharmaceutical composition have tonify Qi of the kidney, the effect of clearing away heat-damp and promoting diuresis, inducing diuresis for treating stranguria syndrome, urinary tract infection such as the frequent micturition of clinical practice due to suffer from a deficiency of the kidney, urgent micturition, dysurea.This pharmaceutical composition can be prepared into different dosage form at needs of patients in addition, is convenient to take, and is easy to carry.
Another purpose of medicine of the present invention works out the raw material of Chinese medicine medicine that utilizes in this medicament exactly, prepares the pharmaceutical preparation that function admirable meets Pharmacopoeia of the People's Republic of China standard, preparation technology is simple in this invention, raw medicinal material is few, has reduced production cost, has alleviated patient's financial burden.
For achieving the above object, the pharmaceutical composition of treatment urinary tract infection provided by the invention is formed by the following raw medicaments in portion by weight processing and preparing:
Radix Astragali 10-20 part Rhizoma Alismatis 20-30 part Poria 10-20 part Herba Dianthi 8-15 part
Herba Epimedii 8-15 part Fructus Lycii 10-20 part Herba Plantaginis 8-15 part Herba Lysimachiae 5-15 part.
Preferred plan is formed by the following raw medicaments in portion by weight processing and preparing:
12 parts of 15 portions of Herba Dianthis of 25 parts of Poria of 15 portions of Rhizoma Alismatis of the Radix Astragali
10 parts of 12 portions of Herba Lysimachiaes of 15 portions of Herba Plantaginiss of 12 parts of Fructus Lycii of Herba Epimedii.
A kind of pharmaceutical composition for the treatment of the urinary tract inflammation of the present invention can be prepared into capsule, tablet, granule.
Described weight portion can be weight metering units such as gram, two, jin, kilogram, ton.
Pharmaceutical composition of the present invention can adopt respectively the distinguish the flavor of medical material of conventional method in will writing out a prescription to carry out compatibility in proportion, makes various clinical suitable dosage forms by existing preparation process, and the used medical material of respectively distinguishing the flavor of is the Chinese crude drug that commercially available process is up to the standards.
Preparation method of the present invention comprises the steps:
(1) it is standby to get above-mentioned each bulk drugs;
(2) get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 4～6 times of water gagings and decoct 2～4 times, each 2-4 hour, filter, merging filtrate is condensed into the extractum that relative density is 1.15-1.25; Add appropriate amount of auxiliary materials such as granulations such as starch, dextrin, drying, granule or filled capsules or tabletting are made in sterilization, get final product.
The preferred version of preparation method of the present invention comprises the steps:
(1) it is standby to get above-mentioned each bulk drugs;
(2) get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 5 times of water gagings and decoct 3 times, each 3 hours, filter, merging filtrate is condensed into relative density and is 1.20 extractum; Add appropriate amount of auxiliary materials such as granulations such as starch, dextrin, drying, granule or filled capsules or tabletting are made in sterilization, get final product.
Why the present invention selects for use above-mentioned medical material as raw material, is because they have following effect:
The Radix Astragali: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.It is weak to be used for the deficiency of vital energy, anorexia and loose stool, and sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst for a long time and do not hold back, the blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Rhizoma Alismatis: diuresis, clearing away damp-heat.Be used for dysuria, edema distension, the oliguria of having loose bowels, dizziness due to fluid-retention, the puckery pain of pyretic stranguria; Hyperlipidemia.
Poria: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Be used for the edema oliguria, the phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in the loose stool, irritability, palpitation with fear insomnia.
Herba Dianthi: inducing diuresis for treating stranguria syndrome, removing blood stasis stimulates the menstrual flow.Be used for pyretic stranguria, stranguria with blood, stranguria caused by urinary stone, urinary obstruction is drenched the puckery pain of drop, the menstruation apolipsis.
Herba Epimedii: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Be used for impotence and seminal emission, the muscles and bones flaccidity is soft, rheumatic arthralgia, numbness contracture; Climacteric hypertension disease.
Fructus Lycii: nourishing the liver and kidney, replenishing vital essence to improve eyesight.Be used for the asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.
Herba Plantaginis: clearing away heat and promoting diuresis, eliminate the phlegm removing heat from blood, detoxifcation.Be used for the edema oliguria, the puckery pain of pyretic stranguria, heat-damp in summer dysentery, phlegm-heat cough, hematemesis and epistaxis, carbuncle sore tumefacting virus.
Herba Lysimachiae: eliminating damp-heat, treating stranguria, detumescence.Be used for pyretic stranguria, the husky pouring urinated and puckeryly had a pain jaundice dark coloured urine, carbuncle furuncle, venom, liver and bile stone, lithangiuria.
Pharmaceutical composition provided by the invention have tonify Qi of the kidney, the effect of clearing away heat-damp and promoting diuresis, inducing diuresis for treating stranguria syndrome, be used to suffer from a deficiency of the kidney, the urinary tract inflammation of the damp and hot frequent micturition that causes, urgent micturition, dysurea.
In order to illustrate that medicine of the present invention has significant curative effect to treatment urethra inflammation, the present invention is through clinical treatment 150 examples, 85 examples of fully recovering, produce effects 41 examples, 14 examples that take a turn for the better, invalid 10 examples.Cure rate 56.7%, obvious effective rate 27.3%, improvement rate 9.3%, inefficiency 6.7%.
The excellent results of pharmaceutical composition of the present invention and preparation method thereof is:
1. medicament of the present invention is made by pure Chinese medicine, does not contain chemical components, does not contain hormone, have no side effect, treating both the exterior and interior, reach better tonify Qi of the kidney, the effect of inducing diuresis for treating stranguria syndrome;
2. this medicament can be prepared into different dosage form at needs of patients, is convenient to take, and is easy to carry;
3. technology of the present invention is simple, has reduced production cost, has alleviated patient's financial burden.
The specific embodiment
Below with embodiment a kind of pharmaceutical composition for the treatment of the urinary tract inflammation of the present invention and preparation method thereof is further described; this will help the present invention and effect thereof are further understood; embodiment does not limit protection scope of the present invention, and its protection domain is decided by claim.
Embodiment 1
Used crude drug is Radix Astragali 100g, Rhizoma Alismatis 200g, Poria 100g, Herba Dianthi 80g, Herba Epimedii 80g, Fructus Lycii 100g, Herba Plantaginis 80g, Herba Lysimachiae 50g in the present embodiment;
Its preparation method is:
Get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 4 times of water gagings and decoct 2 times, each 2 hours, filter, merging filtrate is condensed into relative density and is 1.15 extractum; It is an amount of to add starch, granulate, and drying, granule 500g is made in sterilization, gets final product.
Embodiment 2
Used crude drug is Radix Astragali 200g, Rhizoma Alismatis 300g, Poria 200g, Herba Dianthi 150g, Herba Epimedii 150g, Fructus Lycii 200g, Herba Plantaginis 150g, Herba Lysimachiae 150g in the present embodiment;
Its preparation method is:
Get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 6 times of water gagings and decoct 4 times, each 4 hours, filter, merging filtrate is condensed into relative density and is 1.25 extractum; It is an amount of to add starch, granulate, and drying, granule is made in sterilization, is pressed into 1000, gets final product.
Embodiment 3
Used crude drug is Radix Astragali 150g, Rhizoma Alismatis 250g, Poria 150g, Herba Dianthi 120g, Herba Epimedii 120g, Fructus Lycii 150g, Herba Plantaginis 120g, Herba Lysimachiae 100g in the present embodiment;
Its preparation method is:
Get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 5 times of water gagings and decoct 3 times, each 3 hours, filter, merging filtrate is condensed into relative density and is 1.20 extractum; Add appropriate amount of auxiliary materials such as granulations such as starch, dextrin, drying, granule is made in sterilization, and filled capsules is made 1000, gets final product.
Claims (5)
1. pharmaceutical composition for the treatment of the urinary tract inflammation is characterized in that being formed by the following raw medicaments in portion by weight processing and preparing:
Radix Astragali 10-20 part Rhizoma Alismatis 20-30 part Poria 10-20 part Herba Dianthi 8-15 part
Herba Epimedii 8-15 part Fructus Lycii 10-20 part Herba Plantaginis 8-15 part Herba Lysimachiae 5-15 part.
2. a kind of pharmaceutical composition for the treatment of the urinary tract inflammation according to claim 1 is characterized in that being formed by the following raw medicaments in portion by weight processing and preparing:
12 parts of 15 portions of Herba Dianthis of 25 parts of Poria of 15 portions of Rhizoma Alismatis of the Radix Astragali
10 parts of 12 portions of Herba Lysimachiaes of 15 portions of Herba Plantaginiss of 12 parts of Fructus Lycii of Herba Epimedii.
3. according to claim 1 or 2 one of them described a kind of pharmaceutical composition for the treatment of the urinary tract inflammation, it is characterized in that preparation is capsule, tablet, granule.
4. according to claim 1 or 2 one of them described a kind of preparation of drug combination method that are used for the treatment of the urinary tract inflammation, it is characterized in that comprising the steps:
(1) it is standby to get above-mentioned each bulk drugs;
(2) get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 4～6 times of water gagings and decoct 2～4 times, each 2-4 hour, filter, merging filtrate is condensed into the extractum that relative density is 1.15-1.25; Add appropriate amount of auxiliary materials such as granulations such as starch, dextrin, drying, granule or filled capsules or tabletting are made in sterilization, get final product.
5. a kind of preparation of drug combination method for the treatment of the urinary tract inflammation according to claim 4 is characterized in that comprising the steps:
(1) it is standby to get above-mentioned each bulk drugs;
(2) get the Radix Astragali, Rhizoma Alismatis, Poria, Herba Dianthi, Herba Epimedii, Fructus Lycii, Herba Plantaginis, Herba Lysimachiae and add 5 times of water gagings and decoct 3 times, each 3 hours, filter, merging filtrate is condensed into relative density and is 1.20 extractum; Add appropriate amount of auxiliary materials such as granulations such as starch, dextrin, drying, granule or filled capsules or tabletting are made in sterilization, get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2010106058120A CN102068571A (en) | 2010-12-23 | 2010-12-23 | Medicinal composition for treating urinary tract inflammation and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2010106058120A CN102068571A (en) | 2010-12-23 | 2010-12-23 | Medicinal composition for treating urinary tract inflammation and preparation method thereof |
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| CN102068571A true CN102068571A (en) | 2011-05-25 |
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| CN2010106058120A Pending CN102068571A (en) | 2010-12-23 | 2010-12-23 | Medicinal composition for treating urinary tract inflammation and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816288A (en) * | 2014-03-21 | 2014-05-28 | 赵世明 | Traditional Chinese medicine composition for treating urinary tract inflammations |
| CN104027617A (en) * | 2014-05-15 | 2014-09-10 | 当涂县科辉商贸有限公司 | Traditional Chinese medicine composition for treating urinary tract infection |
| CN110170010A (en) * | 2019-07-12 | 2019-08-27 | 孙宇 | It is a kind of for treating Chinese medicine compositions of diseases such as frequent micturition, urgent urination, the urinary incontinence and the preparation method and application thereof |
-
2010
- 2010-12-23 CN CN2010106058120A patent/CN102068571A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103816288A (en) * | 2014-03-21 | 2014-05-28 | 赵世明 | Traditional Chinese medicine composition for treating urinary tract inflammations |
| CN104027617A (en) * | 2014-05-15 | 2014-09-10 | 当涂县科辉商贸有限公司 | Traditional Chinese medicine composition for treating urinary tract infection |
| CN110170010A (en) * | 2019-07-12 | 2019-08-27 | 孙宇 | It is a kind of for treating Chinese medicine compositions of diseases such as frequent micturition, urgent urination, the urinary incontinence and the preparation method and application thereof |
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Application publication date: 20110525 |