CN102058862B - Externally applied medicament for pediatric umbilical part and preparation method thereof - Google Patents

Abstract

The invention discloses a Chinese medicinal plaster, in particular an externally applied medicament for a pediatric umbilical part and a preparation method thereof. The externally applied medicament for the pediatric umbilical part is characterized by being prepared from the following components: common burreed rhizome, curcuma zedoary, pangolin scales, medicine terminalia fruit, pepper, hawthorn, pharbitis seed, clove, Indian buead, medicinal evodia fruit, cinnamon, atractylodes rhizome, areca seed, oriental waterplantain rhizome, plantain seed, dried ginger, cuttlebone, radish seed, malt, amomum fruit, borneolum, musk and honey. The Chinese medicinal plaster is specially used for treating pediatric indigestion, diarrhea, anorexia, dyspepsia and malnutrition; the various medicaments are combined to activate qi, blood circulation and coronary circulation so as to fulfill the aim of tonification and purgation in combination; the plaster is safe in clinic application; medicament concentration in tissues of the umbilical part is obviously higher than blood concentration in the tissues of the umbilical part; therefore, the plaster is brought into full effect, the local curative effect is obviously superior to that of internal treatment, and the plaster has quick response, broad indication, is safe in use and has less toxic or side effect. 150 cases are treated in all, and the total effective rate reaches 96 percent.

Description

A kind of children's's umbilical part medicine for external use and preparation method thereof

(1) technical field

The present invention relates to a kind of Chinese medicine patch, particularly a kind of children's's umbilical part medicine for external use and preparation method thereof.

(2) background technology

Children's be prone to suffer from the some diseases of digestive system, as have loose bowels, constipation, anorexia, infantile malnutrition etc., like untimely treatment; Can have influence on children's's growth promoter, infantile malnutrition is owing to improper feeding, or multiple sickness influence; Cause that spleen and stomach function is impaired, the gas-liquid consumption is hindered and a kind of chronic disease of forming, it is obviously seasonal that morbidity does not have, and is more common in the infant in 2-7 year; Clinical with become thin, anemia, hair are wan and sallow, have no appetite for food; Refreshing tired uneasy, two just be mainly to show unusually, comprises infantile malnutrition, nutritional anemia, chronic indigestion, rickets and some avitaminosis, the apositia of modern medicine etc.Stagnant be meant children's's internal damage caused by infantile dyspepsia, stop gathering middle Jiao, long-pending and do not change, the not all right formed a kind of gastrointestinal tract disease of the stagnation of QI not think the breast food, is eaten without digesting, distension and fullness in the abdomen, and the halitosis, the thin or constipated acid in big loose stool is smelly to be characteristic.The main cause that causes primary disease is an excess in feeding, injures taste, causes transformation and transportation of the spleen and stomach imbalance, or weakness of the spleen and stomach, and the fortuneization of becoming thoroughly decomposed is too late, and the breast food is stagnated and do not changed, and its sick position is at taste, and basic pathology is changed into breast and eaten and stop gathering the middle part of gastric cavity, amasss and does not change, and the stagnation of QI is not all right.Stagnating belongs to the dysfunction of western medicine chronic digestible, and its main clinical manifestation is: anorexia, eat without digesting, and the abdominal part distension, it is uncomfortable to defecate etc.According to the saying of the traditional Chinese medical science, the reason that causes stagnating has two kinds of spleen injury and weakness of the spleen and stomach; On the other hand; The deficiency of vital energy comprises vigour, pectoral qi, defends the deficient of gas by traditional Chinese medical science term, and the going down of the promotion of gas, warm, defence, astringency inducing and gasification function; Thereby the low or decline of some functional activity that causes body, the weak phenomenon of degradation under the resistance against diseases.The deficiency of vital energy possibly brought: easily perspiration, malaise, down in spirits, dizzy tinnitus, abundant expectoration or edema is arranged, the deficiency of vital energy also can cause function to go down, thereby shows the weak signs of a series of internal organs.Therefore can find out, the deficiency of vital energy be because of, the internal organs weakness is a fruit, the internal organs weakness then causes diseases such as gastrointestinal retention.Ancients have two kinds of explanations to the implication of infantile malnutrition disease: one says, " infantile malnutrition person is also sweet " thinks that the occurrence cause of infantile malnutrition disease is children's's surfeit delicious food, raw food, and impairing the spleen and stomach with the passing of time gradually becomes infantile malnutrition disease; Another says " infantile malnutrition person does also ", refers to that gas-liquid is dry, emaciated physique.The former says its cause of disease, and the latter states its symptom.The primary disease onset is slow, course of disease delay, and the state of an illness is complicated, has a strong impact on children's upgrowth and development, very then threat to life.Stagnant damaging the spleen and stomach, disease is met yellow leanness, hypotrichosis, lassitude, appetite is not good enough, newborn dyspepsia.The dyspepsia due to improper feeding person, disease sees that one full year of life infant feeding reduces, the nausea and vomiting lump in breast has the lactic acid stink in mouthful; Abdominal distention is cryed, sleep disorder, and stool is time frequently, color has the milk lobe in vain, or constipation, and red tongue, tongue are white thick or yellow thick, the fingerprint purple.Control suitable the spleen and stomach regulating, de-emulsify stagnates.Hinder the trencherman, disease is seen anorexia, nausea and vomiting, and expectorating acid is smelly, abdominal distention or stomachache, sleep disorder, agitation is cry and screamed, and stool acid is smelly, and poor mixing do not changed red tongue, thick, yellow and greasy fur, rolling pulse.Control suitable the spleen and stomach regulating, relieving dyspepsia.Infantile malnutrition, disease meeting color is sallow, emaciated physique, the hair Huang is rare, the enlarged abdomen blue veins, big head with slender neck, order does not have brilliance, indigestion and loss of appetite anorexia, the dysphoria with smothery sensation dry lip, the sleeping with eyes half-closed that dosses, aqueous-grainy diarrhea, the few Tianjin of light red tongue, or red tongue tongue light, deep pulse is unable or count accurately.The reason of infantile anorexia: (1) direct stimulation (2) (3) of excessive eating and drinking food variable interval (4) snacks too much cause infantile anorexia.The treatment means of doctor trained in Western medicine adopts digestion diarrhea medicine more at present, and curative effect is low, and side effect is big, and dependency is strong, cures the symptoms, not the disease.The traditional Chinese medical science is effected a permanent cure, but the process that decocts of Chinese herbs decoction trouble is time-consuming, and difficulty is taken again, and travelling is carried also inconvenient, and oral curative effect is not rapid.

(3) summary of the invention

The present invention provides a kind of children's's umbilical part medicine for external use evident in efficacy, safe and reliable, easy to use and preparation method thereof in order to remedy the deficiency of prior art.

The present invention realizes through following technical scheme:

A kind of children's's umbilical part medicine for external use, its special character is: the component by following parts by weight is processed:

Triangular 30-70 part Rhizoma Curcumae 30-70 part Squama Manis 30-70 part

Fructus Chebulae 20-50 part Fructus Piperis 20-50 part Fructus Crataegi 30-70 part

Semen Pharbitidis 20-50 part Flos Caryophylli 20-50 part Poria 30-70 part

Fructus Evodiae 20-50 part Cortex Cinnamomi 20-50 part Rhizoma Atractylodis 30-70 part

Semen Arecae 30-70 part Rhizoma Alismatis 20-50 part Semen Plantaginis 30-70 part

Rhizoma Zingiberis 20-50 part Endoconcha Sepiae 20-50 part Semen Raphani 20-50 part

Fructus Hordei Germinatus 20-50 part Fructus Amomi 20-50 part MEIHUA BINGPIAN 5-15 part

Moschus 0.5-1.5 part, above-mentioned all medicine weight 1-2 Mel doubly.

Children's's umbilical part medicine for external use of the present invention, its preferred scheme is: the component by following parts by weight is processed:

50 parts of 50 parts of Squama Maniss of triangular 50 parts of Rhizoma Curcumae

50 parts of 30 portions of Fructus Crataegis of 30 portions of Fructus Piperiss of Fructus Chebulae

50 parts in 30 parts of Poria of 30 portions of Flos Caryophyllis of Semen Pharbitidis

50 parts of 30 parts of Rhizoma Atractylodis of 30 portions of Cortex Cinnamomis of Fructus Evodiae

50 parts of 30 portions of Semen Plantaginiss of 50 portions of Rhizoma Alismatis of Semen Arecae

30 parts of 30 parts of Semen Raphanis of 30 portions of Endoconcha Sepiaes of Rhizoma Zingiberis

10 parts of 30 parts of MEIHUA BINGPIANs of 30 parts of Fructus Amomis of Fructus Hordei Germinatus

1 part in Moschus, above-mentioned all medicine weight 1.2-1.5 Mel doubly.

The method for preparing of children's's umbilical part medicine for external use of the present invention comprises the steps:

(1) with the solid material clean dry, take by weighing each crude drug of said parts by weight, mixing after the micronizing, autoclaving gets medicated powder;

(2) place pot internal heating to boiling Mel, remove floating foam and impurity, put again in the pot slow endure to rufous from fire;

(3) Mel of tempering is poured in the medicated powder, medicated powder is stirred on the limit of falling Mel, limit, stops down when not having dried medicated powder sweetly, rubs patent medicine group;

(4) honeyed pill is processed by conventional method by medicine group, honeyed pill is processed patch.

Therapeutic Method: the time spent gets on the sticking umbilicus of plaster subsides fixing, and every subsides were pasted 3 days, and be a course of treatment January, and can cure general 1-3 course of treatment.

Points for attention:

1. the preceding elder generation of treatment to umbilicus and surrounding skin routine disinfection, to avoid infection with 75% cotton ball soaked in alcohol, and skin has damaged person, had better not use umbilicus treatment method;

2. get dorsal position, fully appear umbilical part, external application gauze or adhesive plaster are adjacent to after the medication, and also available wide strap is fixed, and is covered in umbilical part;

3. since umbilicus to treat drug absorption very fast, abdominal discomfort or dull pain sense can appear so medication begins several days individual patient (especially with walk to scurry or during cold and cool medicine), can die away after general several days;

4. this therapy should be carried out indoor, notes warmingly, in order to avoid the patient suffers from cold, body void person, old people, children's should note especially;

5. skin has the irritated careful usefulness of ulcer.

The purpose of refining Mel is removed impurity, and like dead honeybee, destructive enzyme killing microorganisms such as waxiness are suitably removed part moisture to strengthen bonding force, promote the conversion of part sugar, increase stability.The refined honey degree is divided into three kinds of tender honey, middle honey, old honey:

(1) tender honey: Mel is placed in the pot, be heated to boiling, temperature 105-115 ℃, water content is about 20%, and relative density is about 1.34, and color deepens slightly toughness slightly;

(2) honey in: Mel is continued heating reach 116-118 ℃, water content is about 10%, and color is light red, and surface boiling even glossy rill, is twined toughness with hands, but two handss are when leaving, no fine filaments appearance;

(3) old honey: honey is continued to be heated to 119-122 ℃, and water content is about 4%, and relative density is more than 1.4, and color is rufous, and the rufous bubble is being seethed on the surface, and viscosity is strong, two finger sth. made by twisting, white long filament appears, splash into beading in the water and diffusing.

The composition of pressing spice is different, endures respectively during refining Mel to be old honey, middle honey or tender honey: spice is main with grass roots, bark, and fiber is difficult for the old honey of agglutinating usefulness (but be not caking ability that ' dripping into pearl ' that kind has surpassed old honey, the pill of processing is stiff) more; In the spice to contain sugar or to contain colloid or the starch-containing more easy agglutinating tender honey of using; Honey in the moderate usefulness of spice composition.And the judgement of old honey, middle honey, tender honey practise to be claimed " seeing heat color ", grasps badly, and the pill of making is just of low quality.

The amount of refining Mel doubly get final product with the 1.2-1.5 of all medicine weight, and more as if saccharic in the spice, colloid, starch, then the 1-2 with all medicine weight doubly is advisable.The soft durometer of honeyed pill receives the old tender influence of refined honey, and the method for adjustment is can add the Mel that has refined in right amount too firmly; The too soft medicated powder that can add is in right amount mixed well fully repeatedly and is got final product.

Will seal after honeyed pill processed patch, shady and cool place preserves.

Umbilicus; Being positioned at abdominal part center recess, is a life root base of a fruit tissue that carries over after neonatal umbilical cord comes off, by name refreshing; Claim " Qizhong ", " Qishe ", " gas closes ", " dimension is closed ", " ring paddy ", " umbilical cord " again, belong to an important acupuncture point on the traditional Chinese medical science conception vessel.The traditional Chinese medical science claims that the Qizhong is " Shenque ", and umbilicus occupies the center, and is like the fault of door, magic congenital." investigation of name through the cave " points out that " god " is quick-witted vitality, and " fault " is the door that the monarch occupies the city, and be visible, and SHENQUE acupoint is the place that vitality is lived.When fetus grows in parent, when growing, all relies on the blood supply and the nutrient delivery of umbilical cord, to keep the vital movement of fetus, so the ancient Chinese medicine scholar regards umbilicus the origin of the congenital foundation, life as, so be referred to as Shenque.Can find out the particularity and the importance of umbilicus (SHENQUE acupoint) thus, basic for life." difficult warp. 66 difficulties " say: " and interrenal qi person under the umbilicus, people's life also, 12 warps at all also." SHENQUE acupoint is positioned at the umbilical part of big abdomen central authorities; be congenital umbilical cord, the Qishe of the day after tomorrow is between the middle part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels; think is through the remittance sea of gas; the vital organs of the human body this, and passages through which vital energy circulates, the vital organs of the human body that SHENQUE acupoint and body weight for humans are wanted connect each other, communicate, thereby make it can play the therapeutical effect of uniqueness through its particularity.

Umbilicus is treated has many-sided function and effect, is summarized as follows;

(1) the temperature gas that activates yang, recuperating depleted YANG Soviet Union faints, and Zhang Jiebin says: ' though the ground of Zhiyin, and the residence of real argument sun.' yang-energy be people's life this, what is called has saying of ' yang-energy be living, lose the yang-energy person and die young '.Umbilicus is treated with warm drug effect umbilical part, through the warm stimulation of medicine, and the excited respiratory center of ability, the accelerate blood circulation is led to the yang-energy temperature or the depletion of YANG must be consolidated, thereby reaches the purpose that recuperating depleted YANG is fainted again and revived;

(2) dredge the meridian passage, promoting the circulation of QI to relieve pain, select for use warm medicine to paste umbilicus after, by the logical effect of the temperature of medicine, can excite QI of channels and collaterals, can play dredge the meridian passage promotion QI-blood circulation, reach the purpose of ' general rule is obstructed ';

(3) the logical three warmers of transferring, inducing diuresis to remove edema, three warmers person master certainly show disrespect on, and the stimulation of utilizing the medicine or the method for subsides can excite the gasification function of three warmers behind umbilicus, promote that mechanism of qi fortune is smooth, and channel tunnel is sensible, makes normal urination, reaches the repercussive purpose;

(4) invigorating the spleen and regulating the stomach, ascending the clear and descending the turbid, umbilicus are the hinge of the middle part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, the stimulation that umbilicus is treated through medicine or his method has promoted its Absorption, makes spleen and gastrointestinal function vigorous, lucid YANG getting to ascend, turbid yin descends, and reaches invigorating the spleen and regulating the stomach, sending down the abnormal ascending QI antidiarrheal purpose;

(5) convergence hidroschesis, treating spontaneous emission and leukorrhagia, umbilicus are treated the conduction of back through drug absorption and meridians, have adjusted the imbalance of internal organs negative and positive, and it is smooth that QI and blood is transferred, and battalion defends tonneau, and energy Tianjin is returned, thereby plays the effect that arresting sweating and strengthening superficial resistance, arresting seminal emission are with admittedly;

(6) Chong and Ren Meridians regulating is Gu through antiabortive, umbilicus closely dashes to appoint to superintend and direct is with four arteries and veins, wherein appoints the sea for all the moon, main uterus; CHONG meridian being the blood pool, main reproduction, married woman's warp, band, tire, product are with four pulse manners of breathing to close at disease and towards superintending and directing, and umbilicus is treated the effect that can play temperature compensating below element, Chong and Ren Meridians regulating;

(7) strong health care is prevented disease and prolonged life, and umbilicus is congenital umbilical cord; Be again the Qishe of the day after tomorrow, the origin of the first day after tomorrow all belongs to this, acts on the Qizhong with warm medicine; The ability warming the kidney to invigorate YANG, invigorating the spleen and replenishing QI improves body's immunological function; Thereby reach the enhances human body resistance against diseases, play health care, diseases prevention, life prolonging.

From the modern medicine angle:

(1) umbilical region administration is without digestive system, and is less through liver, avoided gastral stimulation and the liver metabolism destruction to ingredient, thereby made medicine bring into play curative effect better;

(2) teleneuron of medicine irritation umbilical part influences organism nervous system and plays Accommodation.See that from the region of anatomy umbilical part has the main plexus nervorum of autonomic nerve to exist, like coeliac plexus, intermesenteric plexus, hypogastric plexus and pelvic cavity clump etc. near abdominal cavity and pelvic cavity in abdominal cavity and the pelvic cavity; Also has topmost neuroganglion; Like abdominal cavity joint, mesentery joint, aorta nephromere, ganglion mesentericum inferius; The internal organs and the blood vessel of their all abdominal cavities of domination and pelvic cavity comprise diaphram, liver, spleen, stomach, intestinal, kidney, adrenal gland, ureter, bladder, ovary, uterus (or deferent duct) and affiliated whole blood vessels thereof, therefore; Umbilical part has absorbability more by force and rapidly, and good experience function and conduction function are arranged.All can stimulate the local nerve tip when executing when controlling in umbilical part with the medicine of the various suitable state of an illness; Again through neural reflection and conduction; The function of adjustment body autonomic nerve; Improve the physiological activity and the pathological change of internal organs and tissue, strengthened the immunity and the resistance against diseases of body, thus the purpose that reaches building body, prevents and cures diseases;

(3) skin of umbilical part is thin tender, and SHENQUE acupoint supplies cyotrophy, growth with female blood from here in embryo development procedure; It also is the last closed place of stomach wall; Horny layer of epidermis is the thinnest, barrier function a little less than, and fat-free mass under the umbilicus; The skin fascia directly links to each other, and these all help the direct absorption of medicine.

The relation of umbilicus and meridians, internal organs:

Umbilicus treats why to treat hundreds of disease of whole body, and prevention and health care's effect is arranged, and is that also there is extraordinary relation in meridians, the internal organs of itself and human body.Meridians are one of human body its specific structure and ingredient; Be the passage of people's running body QI and blood, it is inside and outside, up and down that it links up body, is that human body becomes complete, an organic entity; And, make each function of human body be able to keep coordinating and relative equilibrium so as to qi and blood circulation promotion, battalion's negative and positive.Umbilicus and conception vessel, governor vessel, chong channel, dai channel are in close relations, are 4 passages through which vital energy circulates area-covereds.Umbilicus at first is an important acupuncture point on " conception vessel ", and acromphalus is gone in the capable abdomen of conception vessel center.Conception vessel crosses through its arteries and veins gas and each yin channel of brothers for " sea of all the moon " is contained in foot three cloudy and hands three YIN pulse gas.In the middle utmost point, Guanyuan acupoint and sufficient sp 6 meeting, in Tiantu, Lianquan cave and Yin Link Channel, Yin Link Vessel intersection,, meet at the Three Yin channels of hand on the Three Yin Channels of Foot in Yinjiao point and chong channel intersection, so conception vessel has been got in touch all yin channel, just umbilicus communicates with the yin channel of whole body through conception vessel.So umbilicus is treated can influence other passages through which vital energy circulates through QI-blood circulation effect in the meridians, thus reach spleen invigorating stomach warming, recuperating depleted YANG and rescuing the patient from collapse, Soviet Union faint take off admittedly, the logical effect such as stagnant of stomach function regulating reason intestinal, promoting the circulation of QI to induce diuresis, eliminating stagnation.So during the passages through which vital energy circulates generation pathological change of conception vessel, governor vessel, chong channel, dai channel and whole body, the hernia of appearance, leukorrhagia, upper abdominal pain, lower abdominal pain, hemorrhoid, have loose bowels, hematuria, cough, dysuria, singultus, vomiting, lumbago, edema, tympanites, menoxenia, mammary swelling, mastalgia and motherhood disease and diseases such as breast abdominal viscera dysfunction, vigour weakness can obtain medical treatment through executing of SHENQUE acupoint controlled.SHENQUE acupoint on the physiology with treatment on representative to conception vessel, governor vessel, chong channel, dai channel and brothers' three yin meridians especially, this argument is already by a large amount of medical practices and experiment proof.

In addition, ancients also think umbilicus with have following special relationship through resuming of pulse:

Umbilicus is treated immune effect:

SHENQUE acupoint is the strong cave commonly used of health care, and modern medicine thinks that SHENQUE acupoint has the effect of antiinflammatory, antibacterial and enhancing human body immunity power, so umbilicus is a significant points with special treatment meaning.Ancients fill out the umbilicus moxa-moxibustion with male Oletum Ratti norvegici, but life lengthening, its reason is that male Oletum Ratti norvegici fills out the umbilicus moxibustion and act on immune system, improves immune function of human body, has defying age and antineoplastic action, same Chinese medicine patch umbilicus also can human body immunity improving power.The mechanism that umbilicus is treated the human body immunity improving function is the skin by the medicine irritation umbilical part, and through the neural reflex effect, the regulatory function of excitating organism forms some antibody of body, and immunity improves, thereby improves human body defending and fighting against diseases function.In addition, the modern mathematics theoretical proof, umbilicus is positioned at the golden point of body, is the best use of point of adjustment human body.

Medicine mainly contains through the approach that umbilical part absorbs:

(1) through umbilical part passage horny layer transhipment (comprising cell internal diffusion and intercellular substance diffusion) and the transhipment of epidermis deep layer, and absorbed medicine can get into blood circulation through one or more approach;

(2) hydration: cuticular water content is the function of envionmental humidity, Chinese medicine patch umbilical part external application " shape attach in and do not leave, gas-tight storing and not eliminating "; A kind of sweat of local formation is difficult to evaporate the air-tight state of diffusion; Make the horny layer water content increase to 50% by 5%-15%, horny layer is expandable into porous state behind hydration, is easy to medicine and penetrates; Therefore the transdermal speed that facts have proved medicine can increase 4-5 doubly, can also make Pi Wen increase to 37 ℃ of accelerate blood circulations from 32 ℃ simultaneously;

(3) Action of Surfactant: the soap that contains in the honeyed pill, it is a kind of surfactant, can promote the absorption of passive diffusion, increases the percent of pass of epidermis lipid membrane to medicine;

(4) facilitation of armaticity medicine: fragrant medicines such as MEIHUA BINGPIAN, Moschus spread on the part, can make corticosteroid transdermal ability improve 8-10 doubly;

(5) Percutaneous absorption enhancer makes medicine be molecularity or the submolecule state is distributed in the substrate equably, is beneficial to rapidly equably that Transdermal absorption gets into blood circulation, has both promoted the absorption of medicine for external use, has kept the stable of haemoconcentration again;

(6) the present invention " be cut in umbilical part, drive in inside, tweezer is in air-breathing; be melted into sepage ", the external treatment medicine directly gets into blood circulation and brings into play the pharmacological action of itself, adjusts each system organization organ dysfunction and body's immunity in addition; Also expansible local blood capillary; The accelerate blood circulation is played the speed governing effect to blood constituent, thereby promotes the osmotic absorption of medicine and propagation to strengthen systemic effect;

(7) patch is through the umbilicus administering mode: medicine discharges from medium, absorbs through umbilicus, subcutaneous blood capillary and carries out the body circulation.

Umbilical compress therapy is that the medicine for preparing is spread on patient's the umbilicus, covers plastic sheeting and gauze, uses immobilization with adhesive tape then.In medical umbilicus treated the history of curing the disease existing more than 2000 year, this position of umbilicus is attached great importance to, claim that it is " Shenque "." Taoist Scriptures " book is explained: " refreshing person, the utmost point of variation also, so name with ' god '; ' fault ' is middle door, to show dignitary." traditional Chinese medical science thinks that umbilicus is heart kidney traffic " door ", promptly spirited ascending, descending, exiting and entering, changes the place of growth and decline, belongs to an important acupuncture point of conception vessel, the vital organs of the human body of leading to are regulated each internal organs physiological activity.Said as Qing Dynasty's well-known doctor Wu Shi machine, " it is deep to have one's ideas straightened out for Shenque administration, the network that can stimulate the menstrual flow away." from umbilical region administration, help medicine return through, drug effect is followed through through sick institute, the adjustment negative and positive of qi and blood to drive away pathogenic factor, reinforcing body resistance, has a very important role to disease preventing and treating.See that from modern medical theory umbilicus skin is the thinnest, pass through the people more easily than other transdermal administration positions.Simultaneously, umbilicus is subcutaneous not to have fatty tissue, and peritoneum has abundant blood vessel under the umbilicus, and external used medicine is prone to absorb, and can get into blood circulation rapidly, and bioavailability is high, and the efficacy of a drug disease institute that can go directly reaches the purpose of treatment.In addition, the umbilical part peripheral nerve is abundant, and oxyesthesia is pressed stimulation through medicine, can also regulate neuroendocrine system, improves the function of each internal organs.Umbilical compress therapy is simple and easy to do, both can alleviate the toxic and side effects of medicine to Liver and kidney, and can exempt endo-medicine again stimulates gastrointestinal, the patient is acceptant be particularly suitable for the taking medicine infant and the old people of difficulty.Wide clinical application is in inside and outside, woman, each section's disease of youngster, and is especially evident in efficacy to gastroenteropathy.

Chinese medicine patch of the present invention is specifically designed to the treatment infantile dyspepsia, has loose bowels, anorexia, stagnant, infantile malnutrition, and all medicines are harmonious and make gas reach the capable beniol of blood, thereby reach the purpose of reinforcement and elimination in combination; Clinical practice safety, the drug level that imposes in the umbilical part local organization is significantly higher than its haemoconcentration, so play a role fully; Local curative effect obviously is superior to treatment by oral administration of medicines, and gets effect rapidly, and indication is wide; Multiple compatibility of drugs utilizes mutual collaborative or resistant function, has improved curative effect; Reduced untoward reaction, safe in utilization, toxic and side effects is few.Treat 156 examples altogether, total effective rate reaches 96%.

(4) specific embodiment

Embodiment 1:

The method for preparing of children's's umbilical part medicine for external use, adopt following steps:

(1) with the solid material clean dry; Take by weighing triangular 50 grams, Rhizoma Curcumae 50 grams, Squama Manis 50 grams, Fructus Chebulae's 30 grams, Fructus Piperis 30 grams, Fructus Crataegi 50 grams, Semen Pharbitidis 30 grams, Flos Caryophylli 30 grams, Poria 50 grams, Fructus Evodiae 30 grams, Cortex Cinnamomi 30 grams, Rhizoma Atractylodis 50 grams, Semen Arecae 50 grams, Rhizoma Alismatis 30 grams, Semen Plantaginis 50 grams, Rhizoma Zingiberis 30 grams, Endoconcha Sepiae 30 grams, Semen Raphani 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Amomi 30 grams, MEIHUA BINGPIAN 10 grams, Moschus 1 gram; Mixing after the micronizing, autoclaving gets medicated powder;

(2) 1000 gram Mel are placed and are heated to boiling in the pot with high heat, remove floating foam and impurity, put again in the pot with slow fire slow endure to rufous from fire;

(3) Mel of tempering is poured in the medicated powder with spoon, in medicated powder, become circumference to stir with thick bamboo chopsticks simultaneously, medicated powder is stirred on the limit of falling Mel, limit, stops down honey when can't see dried medicated powder, but can not add too many, honey how a ball be difficult for shaping, rub patent medicine group after mixing up;

(4) with medicine group when conventional methods such as rubbing and ball are processed honeyed pill and ball, can use a little Semen Sesami oil drop in the centre of the palm so that pill is bright, honeyed pill is processed 3 grammes per square metre pies, in the middle of pressing from both sides with the two-layer plaster quilt of 12 centimetres of specification 12x, patch.

Therapeutic Method: the time spent gets on the sticking umbilicus of plaster subsides fixing, and every subsides were pasted 3 days, and be a course of treatment January, and can cure general 1-3 course of treatment.

Micronizing, autoclaving are prior art, no longer detail.

Embodiment 2:

This children's's umbilical part medicine for external use, process by the component of following weight:

Triangular 30 grams, Rhizoma Curcumae 30 grams, Squama Manis 30 grams, Fructus Chebulae's 20 grams, Fructus Piperis 20 grams, Fructus Crataegi 30 grams, Semen Pharbitidis 20 grams, Flos Caryophylli 20 grams, Poria 30 grams, Fructus Evodiae 20 grams, Cortex Cinnamomi 20 grams, Rhizoma Atractylodis 30 grams, Semen Arecae 30 grams, Rhizoma Alismatis 20 grams, Semen Plantaginis 30 grams, Rhizoma Zingiberis 20 grams, Endoconcha Sepiae 20 grams, Semen Raphani 20 grams, Fructus Hordei Germinatus 20 grams, Fructus Amomi 20 grams, MEIHUA BINGPIAN 5 grams, Moschus 0.5 gram, Mel 580 grams.

Embodiment 3:

This children's's umbilical part medicine for external use, process by the component of following weight:

Triangular 70 grams, Rhizoma Curcumae 70 grams, Squama Manis 70 grams, Fructus Chebulae's 50 grams, Fructus Piperis 50 grams, Fructus Crataegi 70 grams, Semen Pharbitidis 50 grams, Flos Caryophylli 50 grams, Poria 70 grams, Fructus Evodiae 50 grams, Cortex Cinnamomi 50 grams, Rhizoma Atractylodis 70 grams, Semen Arecae 70 grams, Rhizoma Alismatis 50 grams, Semen Plantaginis 70 grams, Rhizoma Zingiberis 50 grams, Endoconcha Sepiae 50 grams, Semen Raphani 50 grams, Fructus Hordei Germinatus 50 grams, Fructus Amomi 50 grams, MEIHUA BINGPIAN 15 grams, Moschus 1.5 grams, Mel 1760 grams.

Embodiment 4: clinical observation

(1) physical data

The inventor carries out clinical observation treatment to 156 routine pediatric patients so far in nineteen ninety-five, and the age 1 was not waited by 7 years old.

(2) Therapeutic Method: the time spent gets on the sticking umbilicus of plaster subsides fixing, and every subsides were pasted 3 days, and be a course of treatment January, and can cure general 1-3 course of treatment.

Points for attention:

1. the preceding elder generation of treatment to umbilicus and surrounding skin routine disinfection, to avoid infection with 75% cotton ball soaked in alcohol, and skin has damaged person, had better not use umbilicus treatment method;

2. get dorsal position, fully appear umbilical part, external application gauze or adhesive plaster are adjacent to after the medication, and also available wide strap is fixed, and is covered in umbilical part;

3. since umbilicus to treat drug absorption very fast, abdominal discomfort or dull pain sense can appear so medication begins several days individual patient (especially with walk to scurry or during cold and cool medicine), can die away after general several days;

4. this therapy should be carried out indoor, notes warmingly, in order to avoid the patient suffers from cold, body void person, old people, children's should note especially;

5. skin has the irritated careful usefulness of ulcer.

(3) efficacy assessment standard

" healing ": the clinical symptoms sign disappears, and recovers normal.

" produce effects ": basic or most of disappearance of clinical symptoms sign.

" effectively ": clinical symptoms is clearly better.

Engineering noise: the clinical symptoms sign does not have improvement.

(4) therapeutic effect:

Clinical cure 114 examples account for 73%; Produce effects 19 examples account for 12%; Effective 17 examples account for 11%; Invalid 6 examples, total effective rate 96%.

Model case:

1 Lee, the man 6 years old, suffers from infantile malnutrition, stagnant, body shows slightly and becomes thin; The few China of shallow complexion, hair is rare slightly, inappetence, spirit is not good enough; Be prone to fly into a rage, big loose stool book or dry and hard uses the embodiment of the invention 1 made patch to paste umbilicus; Every subsides were pasted 3 days, and be a course of treatment January, and cure three courses of treatment does not have recurrence so far.

2 Huangs, the woman, 3 years old, trouble was had loose bowels, distension and fullness in the abdomen, the tripe abdomen is had a pain, and pain is then desired to rush down, and rushes down the back alleviation of pain, and feces acid is smelly, and uneasy sleeping at night does not think to receive food, uses the embodiment of the invention 1 made patch to paste umbilicus, and every subsides were pasted 3 days, and be a course of treatment January, two healings courses of treatment.

3 Zhangs, the woman, 2 years old, stagnant irritated crowing more, sleep uneasy night, inappetence, the abdominal part distension, pain is then desired just, after an action of the bowels alleviation of pain.Use the embodiment of the invention 1 made patch to paste umbilicus, every subsides were pasted 3 days, and be a course of treatment January, and cure a course of treatment, do not have recurrence so far.

4 Hus, man, 4 years old suffer from anorexia, and the xerostomia polydipsia is not liked feed.Use the embodiment of the invention 1 made patch to paste umbilicus, every subsides were pasted 3 days, and be a course of treatment January, and cure a course of treatment, do not have recurrence so far.

Claims (3)

1. children's's umbilical part medicine for external use, it is characterized in that: the component by following parts by weight is processed:

Triangular 30-70 part Rhizoma Curcumae 30-70 part Squama Manis 30-70 part

Fructus Chebulae 20-50 part Fructus Piperis 20-50 part Fructus Crataegi 30-70 part

Semen Pharbitidis 20-50 part Flos Caryophylli 20-50 part Poria 30-70 part

Fructus Evodiae 20-50 part Cortex Cinnamomi 20-50 part Rhizoma Atractylodis 30-70 part

Semen Arecae 30-70 part Rhizoma Alismatis 20-50 part Semen Plantaginis 30-70 part

Rhizoma Zingiberis 20-50 part Endoconcha Sepiae 20-50 part Semen Raphani 20-50 part

Fructus Hordei Germinatus 20-50 part Fructus Amomi 20-50 part MEIHUA BINGPIAN 5-15 part

Moschus 0.5-1.5 part, above-mentioned all medicine weight 1-2 Mel doubly.

2. children's's umbilical part medicine for external use according to claim 1, it is characterized in that: the component by following parts by weight is processed:

50 parts of 50 parts of Squama Maniss of triangular 50 parts of Rhizoma Curcumae

50 parts of 30 portions of Fructus Crataegis of 30 portions of Fructus Piperiss of Fructus Chebulae

50 parts in 30 parts of Poria of 30 portions of Flos Caryophyllis of Semen Pharbitidis

50 parts of 30 parts of Rhizoma Atractylodis of 30 portions of Cortex Cinnamomis of Fructus Evodiae

50 parts of 30 portions of Semen Plantaginiss of 50 portions of Rhizoma Alismatis of Semen Arecae

30 parts of 30 parts of Semen Raphanis of 30 portions of Endoconcha Sepiaes of Rhizoma Zingiberis

10 parts of 30 parts of MEIHUA BINGPIANs of 30 parts of Fructus Amomis of Fructus Hordei Germinatus

1 part in Moschus, above-mentioned all medicine weight 1.2-1.5 Mel doubly.

3. the method for preparing of children's's umbilical part medicine for external use according to claim 1 is characterized in that:

Comprise the steps:

(1) with the solid material clean dry, take by weighing each crude drug of said parts by weight, mixing after the micronizing, autoclaving gets medicated powder;

(2) place pot internal heating to boiling Mel, remove floating foam and impurity, put again in the pot slow endure to rufous from fire;

(3) Mel of tempering is poured in the medicated powder, medicated powder is stirred on the limit of falling Mel, limit, stops down when not having dried medicated powder sweetly, rubs patent medicine group;

(4) honeyed pill is processed by conventional method by medicine group, honeyed pill is processed patch.