CN102056484B - 用于热潮红的类固醇治疗 - Google Patents

用于热潮红的类固醇治疗 Download PDF

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Publication number
CN102056484B
CN102056484B CN200980121663.6A CN200980121663A CN102056484B CN 102056484 B CN102056484 B CN 102056484B CN 200980121663 A CN200980121663 A CN 200980121663A CN 102056484 B CN102056484 B CN 102056484B
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CN
China
Prior art keywords
epoxy
female
hot flashes
hydroxy
beta
Prior art date
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Application number
CN200980121663.6A
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English (en)
Chinese (zh)
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CN102056484A (zh
Inventor
路易斯·蒙蒂
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Pherin Pharmaceuticals Inc
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Pherin Pharmaceuticals Inc
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Publication of CN102056484A publication Critical patent/CN102056484A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
CN200980121663.6A 2008-04-09 2009-04-09 用于热潮红的类固醇治疗 Active CN102056484B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12362208P 2008-04-09 2008-04-09
US61/123,622 2008-04-09
PCT/US2009/040102 WO2009126825A1 (en) 2008-04-09 2009-04-09 Steroid treatment for hot flashes

Publications (2)

Publication Number Publication Date
CN102056484A CN102056484A (zh) 2011-05-11
CN102056484B true CN102056484B (zh) 2014-10-29

Family

ID=41162250

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200980121663.6A Active CN102056484B (zh) 2008-04-09 2009-04-09 用于热潮红的类固醇治疗

Country Status (10)

Country Link
US (2) US20090258040A1 (enExample)
EP (1) EP2278880B1 (enExample)
JP (1) JP5524177B2 (enExample)
KR (1) KR101602802B1 (enExample)
CN (1) CN102056484B (enExample)
AU (1) AU2009234159B2 (enExample)
BR (1) BRPI0910637A2 (enExample)
DK (1) DK2278880T3 (enExample)
MX (1) MX2010011063A (enExample)
WO (1) WO2009126825A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018297270B2 (en) * 2017-07-06 2024-02-15 Dignity Health Novel treatment for hot flushes
EP3955933B1 (en) * 2019-04-15 2023-11-29 Vistagen Therapeutics, Inc. Treatment of migraine
EP4719427A1 (en) * 2023-06-04 2026-04-08 Vistagen Therapeutics, Inc. 1,3,5(10),16-estratetraen-3-yl acetate for use in improving psychomotor or cognitive performance
WO2025217068A1 (en) * 2024-04-08 2025-10-16 Vistagen Therapeutics, Inc. Treatment of dysmenorrhea

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1158966B (de) * 1961-04-29 1963-12-12 Schering Ag Verfahren zur Herstellung von 6-Chlor-1, 2ª‡-methylen-í¸-17ª‡-hydroxyprogesteronestern
US6140316A (en) * 1991-01-07 2000-10-31 Pherin Corporation Estrene steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions
US5303703A (en) * 1991-10-03 1994-04-19 Pherin Corporation Combined neuroepithelial sample delivery electrode device and methods of using same
US6117860A (en) * 1994-08-04 2000-09-12 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to treat paroxistic tachycardia
US6066627A (en) * 1994-08-04 2000-05-23 Pherin Corporation Steroids as neurochemical initiators of change in human blood levels of LH
US6057439A (en) 1994-08-04 2000-05-02 Pherin Corporation Steroids as neurochemical stimulators of the VNO to alleviate symptoms of PMS and anxiety
US6331534B1 (en) * 1994-08-04 2001-12-18 Pherin Pharmaceuticals, Inc. Steroids as neurochemical stimulators of the VNO to alleviate pain
US5994333A (en) * 1994-08-04 1999-11-30 Pherin Corporation Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5563131A (en) * 1994-08-04 1996-10-08 Pherin Corporation Pregnane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods
US5792757A (en) * 1994-08-04 1998-08-11 Pherin Pharmaceuticals 19-nor-pregnane steroids as neurochemical initiators of change in human hypothalamic function
ATE342721T1 (de) * 1996-07-23 2006-11-15 Pherin Pharm Inc Steroide als neurochemische stimulatoren des nasenraumes zur linderung der prämenstrualen symptome
US6165504A (en) * 1998-09-23 2000-12-26 Barr Laboratories, Inc. Methods for treating hot flashes and improving the quality of life of castrated prostatic cancer patients
US6613758B1 (en) 1999-04-02 2003-09-02 Barr Laboratories, Inc. Method for treating osteoporosis in castrated prostatic cancer patients
US6756366B1 (en) * 1999-04-06 2004-06-29 Akzo Nobel N.V. Orally active androgens
US20030045514A1 (en) * 2001-05-03 2003-03-06 Louis Monti 17-Methyleneandrostan-3alpha-ol analogs as CRH inhibitors
US7482029B2 (en) * 2005-04-01 2009-01-27 Bionovo, Inc. Composition for treatment of menopause
ES2433251T5 (es) * 2005-11-14 2020-03-13 Teva Pharmaceuticals Int Gmbh Anticuerpos antagonistas dirigidos contra un péptido relacionado con el gen de la calcitonina y procedimientos que utilizan los mismos
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Hot flushes;Vered Stearns et al;《the lancet》;2002;第36卷(第7期);第1854-1855页 *

Also Published As

Publication number Publication date
JP5524177B2 (ja) 2014-06-18
US20120108558A1 (en) 2012-05-03
EP2278880A4 (en) 2011-08-10
MX2010011063A (es) 2010-11-22
DK2278880T3 (da) 2012-11-12
KR101602802B1 (ko) 2016-03-11
KR20110014147A (ko) 2011-02-10
EP2278880A1 (en) 2011-02-02
US20090258040A1 (en) 2009-10-15
HK1157142A1 (en) 2012-06-29
JP2011518136A (ja) 2011-06-23
AU2009234159B2 (en) 2013-12-19
US8431559B2 (en) 2013-04-30
AU2009234159A1 (en) 2009-10-15
CN102056484A (zh) 2011-05-11
BRPI0910637A2 (pt) 2015-07-28
WO2009126825A1 (en) 2009-10-15
EP2278880B1 (en) 2012-10-10

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