CN102046633B - 取代的螺环状环己烷衍生物 - Google Patents

取代的螺环状环己烷衍生物 Download PDF

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Publication number
CN102046633B
CN102046633B CN200980119293.2A CN200980119293A CN102046633B CN 102046633 B CN102046633 B CN 102046633B CN 200980119293 A CN200980119293 A CN 200980119293A CN 102046633 B CN102046633 B CN 102046633B
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phenyl
cyclohexane
indole
spiro
amine
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CN102046633A (zh
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S·策莫尔卡
B·诺尔特
S·弗罗尔曼
C·欣策
K·林茨
W·施勒德
W·恩格尔贝格尔
H·希克
H·松嫩沙因
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Gruenenthal GmbH
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Gruenenthal GmbH
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
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    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
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    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom

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  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN200980119293.2A 2008-03-27 2009-03-25 取代的螺环状环己烷衍生物 Expired - Fee Related CN102046633B (zh)

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Application Number Priority Date Filing Date Title
EP08005808.4 2008-03-27
EP08005808 2008-03-27
PCT/EP2009/002186 WO2009118173A1 (de) 2008-03-27 2009-03-25 Substituierte spirocyclische cyclohexan-derivate

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CN102046633A CN102046633A (zh) 2011-05-04
CN102046633B true CN102046633B (zh) 2015-03-25

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US (1) US8293758B2 (https=)
EP (1) EP2260042B1 (https=)
JP (1) JP5597188B2 (https=)
KR (1) KR101615505B1 (https=)
CN (1) CN102046633B (https=)
AR (1) AR071068A1 (https=)
AT (1) ATE525379T1 (https=)
AU (1) AU2009228647B2 (https=)
BR (1) BRPI0910607A2 (https=)
CA (1) CA2719742C (https=)
CL (1) CL2009000731A1 (https=)
CO (1) CO6251244A2 (https=)
CY (1) CY1112095T1 (https=)
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EC (1) ECSP11010529A (https=)
ES (1) ES2371230T3 (https=)
HR (1) HRP20110721T1 (https=)
IL (1) IL208278A (https=)
MX (1) MX2010009955A (https=)
NZ (1) NZ587831A (https=)
PE (1) PE20091650A1 (https=)
PL (1) PL2260042T3 (https=)
PT (1) PT2260042E (https=)
RU (1) RU2497824C2 (https=)
SI (1) SI2260042T1 (https=)
TW (1) TWI450899B (https=)
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PL2649044T3 (pl) * 2010-12-08 2018-02-28 Grünenthal GmbH Sposób syntezy podstawionych pochodnych aminocykloheksanonu
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TW201607923A (zh) 2014-07-15 2016-03-01 歌林達有限公司 被取代之氮螺環（４．５）癸烷衍生物
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