CN102037135A - 增强对有鞭毛的细菌的免疫反应的组合物和方法 - Google Patents

增强对有鞭毛的细菌的免疫反应的组合物和方法 Download PDF

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Publication number
CN102037135A
CN102037135A CN2008801169113A CN200880116911A CN102037135A CN 102037135 A CN102037135 A CN 102037135A CN 2008801169113 A CN2008801169113 A CN 2008801169113A CN 200880116911 A CN200880116911 A CN 200880116911A CN 102037135 A CN102037135 A CN 102037135A
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CN
China
Prior art keywords
seq
vaccine
polynucleotide sequence
polypeptide
described method
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Pending
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CN2008801169113A
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English (en)
Chinese (zh)
Inventor
W·博特吉
B·哈格斯
L·博格曼
Y·M·权
K·乔菜
M·考克斯
S·莱顿
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Texas A&M University System
University of Arkansas at Little Rock
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Texas A&M University System
University of Arkansas at Little Rock
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Publication of CN102037135A publication Critical patent/CN102037135A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN2008801169113A 2007-10-30 2008-10-30 增强对有鞭毛的细菌的免疫反应的组合物和方法 Pending CN102037135A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98380307P 2007-10-30 2007-10-30
US60/983,803 2007-10-30
PCT/US2008/081813 WO2009059018A1 (en) 2007-10-30 2008-10-30 Compositions and methods of enhancing immune responses to flagellated bacterium

Publications (1)

Publication Number Publication Date
CN102037135A true CN102037135A (zh) 2011-04-27

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CN2008801169113A Pending CN102037135A (zh) 2007-10-30 2008-10-30 增强对有鞭毛的细菌的免疫反应的组合物和方法

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Country Link
US (1) US9125854B2 (https=)
EP (1) EP2214840B1 (https=)
JP (1) JP2011502165A (https=)
CN (1) CN102037135A (https=)
AU (1) AU2008318615A1 (https=)
BR (1) BRPI0818736A2 (https=)
CA (1) CA2704457A1 (https=)
NZ (1) NZ585776A (https=)
WO (1) WO2009059018A1 (https=)

Cited By (1)

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CN104328136B (zh) * 2014-10-03 2018-04-17 哈尔滨博翱生物医药技术开发有限公司 鸡新城疫病毒毒株rClone30‑fliC的制备及其在鸡新城疫病防治中的应用

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PL2066339T3 (pl) * 2006-09-18 2015-02-27 Univ Arkansas Kompozycje i sposoby zwiększania odpowiedzi immunologicznych
US20080124355A1 (en) 2006-09-22 2008-05-29 David Gordon Bermudes Live bacterial vaccines for viral infection prophylaxis or treatment
PT3097926T (pt) 2007-11-01 2020-01-08 Univ Guelph Composições e métodos de potenciação das respostas imunitárias frente a eimeria
US8647642B2 (en) 2008-09-18 2014-02-11 Aviex Technologies, Llc Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment
ES2643646T3 (es) 2010-01-21 2017-11-23 The Board Of Trustees Of The University Of Arkansas Vectores de vacuna y métodos para potenciar las respuestas inmunitarias
MX350306B (es) 2010-06-09 2017-09-04 Univ Arkansas Vacuna y metodos para reducir una infeccion por campylobacter.
CA2895805A1 (en) 2012-12-18 2014-06-26 Kotzker Consulting Llc Use of cannabinoids and terpenes for treatment of organophosphate and carbamate toxicity
AR094791A1 (es) 2013-02-14 2015-08-26 Univ Arkansas Composiciones y métodos para mejorar las respuestas inmunes ante una infección por eimeria o para limitar una infección por eimeria
AU2014239557B2 (en) 2013-03-15 2019-01-03 The Board Of Trustees Of The University Of Arkansas Compositions and methods of enhancing immune responses to enteric pathogens
CN104789583A (zh) * 2014-01-20 2015-07-22 华中农业大学 一种人源产肠毒素大肠杆菌鞭毛蛋白2FliC融合蛋白及其应用
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
KR102767638B1 (ko) 2016-05-03 2025-02-20 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 면역자극 및 항원 폴리펩티드를 포함하는 효모 백신 벡터, 및 그를 이용하는 방법
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
WO2019040135A1 (en) * 2017-05-12 2019-02-28 Children's Medical Center Corporation NUCLEIC ACIDS HANDLING IMMUNEWAYS

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104328136B (zh) * 2014-10-03 2018-04-17 哈尔滨博翱生物医药技术开发有限公司 鸡新城疫病毒毒株rClone30‑fliC的制备及其在鸡新城疫病防治中的应用

Also Published As

Publication number Publication date
AU2008318615A2 (en) 2010-06-24
NZ585776A (en) 2012-07-27
US9125854B2 (en) 2015-09-08
AU2008318615A1 (en) 2009-05-07
EP2214840A4 (en) 2012-03-07
EP2214840A1 (en) 2010-08-11
CA2704457A1 (en) 2009-05-07
BRPI0818736A2 (pt) 2017-06-13
HK1146644A1 (en) 2011-06-24
JP2011502165A (ja) 2011-01-20
EP2214840B1 (en) 2015-05-06
US20110159026A1 (en) 2011-06-30
WO2009059018A9 (en) 2009-12-30
WO2009059018A1 (en) 2009-05-07

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Address after: American Arkansas

Applicant after: Texas A. & M. Univ Sys

Applicant after: Univ Guelph

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Application publication date: 20110427