CN102018788B - Drug for treating gastropathy, gastric ulcer, abdominal pain, chest distress and chronic pharyngitis, and preparation method thereof - Google Patents

Drug for treating gastropathy, gastric ulcer, abdominal pain, chest distress and chronic pharyngitis, and preparation method thereof Download PDF

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CN102018788B
CN102018788B CN2010101069114A CN201010106911A CN102018788B CN 102018788 B CN102018788 B CN 102018788B CN 2010101069114 A CN2010101069114 A CN 2010101069114A CN 201010106911 A CN201010106911 A CN 201010106911A CN 102018788 B CN102018788 B CN 102018788B
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radix
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radix aconiti
radix glycyrrhizae
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CN102018788A (en
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王宗连
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Abstract

The invention discloses a drug for treating gastropathy, gastric ulcer, abdominal pain, chest distress and chronic pharyngitis, which is prepared by common monkshood mother root, kusnezoff monkshood root, angelica sinensis, and zaocys dhumhade in a certain percentage by weight. The drug disclosed in the invention has the functions of enriching the blood, invigorating the blood circulation, enriching the saliva, restraining the sores, detoxifying, and easing the pain, and is used for treating gastropathy, gastric ulcer, abdominal pain, chest distress, chronic pharyngitis and various joint diseases with quick curative effect and high recovery rate.

Description

A kind of medicine of treating gastropathy, gastric ulcer, stomachache, uncomfortable in chest, chronic pharyngitis and preparation method thereof
Technical field:
The present invention relates to a kind of medicine of treating gastropathy, gastric ulcer, stomachache, uncomfortable in chest and chronic pharyngitis, belong to the field of Chinese medicines.
Background technology:
Gastropathy, gastric ulcer, stomachache, abdominal distention and chronic pharyngitis are a kind of common frequently-occurring diseases; Clinical is principal character with stomachache, gastric acid, abdominal distention; Outbreak influences feed and sleep because of violent pain often; Western medical treatment is main with the local application and the pain relieving of suiting the medicine to the illness, but these medicines also can only carry out partial alleviation or treatment to stomach ulcer, can't solve the recurrence and the healing of ulcer.
Summary of the invention:
Therefore, people better treat gastropathy, gastric ulcer, stomachache, medicine uncomfortable in chest and chronic pharyngitis to curative effect and have great demand, up to now, also do not find any relevant report about medicine of the present invention.The inventor is through research repeatedly, and the repeated validation through animal experiment and clinical trial, works out the treatment gastropathy, gastric ulcer, stomachache of better curative effect, the oral medicinal herb medicine of uncomfortable in chest and chronic pharyngitis finally, thereby accomplished the present invention.
The object of the invention just provides a kind of traditional Chinese medicine secret recipe compositions of more effectively treating gastropathy, gastric ulcer, stomachache, abdominal distention, uncomfortable in chest and chronic pharyngitis.
Another object of the present invention has just provided this traditional Chinese medicine secret recipe preparation of compositions method.
Medicine of the present invention selects Radix Aconiti, Fructus Mume, Radix Glycyrrhizae, Radix Aconiti Kusnezoffii, Radix Angelicae Sinensis, Zaocys, egg to make up; With these drug regimens; Make each efficacy of drugs produce synergism, thereby can effectively treat the recurrence of diseases such as gastropathy, gastric ulcer, joint.Wherein selecting radix aconiti sinensis for use, is because radix aconiti sinensis has another name called monkshood, and its nature and flavor are hot, and heat is poisonous, goes into spleen; The gate of vitality's two warps have dispellieg cold and dampness, the ailment said due to cold or exposure of loosing, and Wen Jing, the function of pain relieving is controlled wind-cold-dampness arthralgia; The severe and wadering arthralgia pain, spasm of limbs, hemiplegia, a wind headache, trusted subordinate's crymodynia, cloudy subcutaneous ulcer pyogenic infections; Select for use dark plum to be because dark plum has another name called plum in fact, smoked plum, tangerine plum meat, its nature and flavor acid, temperature is gone into liver, spleen, lung, large intestine channel, has convergence to promote the production of body fluid; The function of claming ascaris expelling parasite is controlled chronic cough, the abnormal heat polydipsia, and chronic malaria is rushed down for a long time, and dysentery is had blood in stool; Hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, hookworm disease, psoriasis, the triangular mass of mucous membrane growing from the inner corner of the eye; Select for use Radix Glycyrrhizae to be because the Radix Glycyrrhizae nature and flavor are sweet, flat, go into spleen, stomach, lung channel, have and middle emergency, moistening lung, detoxifcation, the function of coordinating the drug actions of a prescription is processed usefulness, controls weakness of the spleen and the stomachly, and food is few, stomachache loose stool, overstrain heating, consumptive lung disease cough, palpitaition, frightened epilepsy; Give birth to usefulness, control abscess of throat, peptic ulcer, ulcer sores, antidote poison and food poisoning; Select for use RADIX ACONITI KUSNEZIFFII to be because its nature and flavor are hot, heat, poisonous, go into liver, spleen, lung channel, search wind prevailing over dampness, eliminating cold to stop pain is opened phlegm; The function of detumescence is controlled wind-cold-dampness arthralgia, paralysis due to windstroke, lockjaw, a wind, coldness and pain in the epigastrium, phlegm addiction; Air parcel, cold dysentery, larynx numbness, ulcer, furunculosis, scrofula is sick; Selecting Radix Angelicae Sinensis for use is that temperature is gone into the heart, liver, the spleen channel, and benefiting blood and regulating blood circulation is arranged because of the sweet suffering of its nature and flavor, menstruction regulating and pain relieving, and the function of moisturizing laxation is controlled irregular menstruation, gathers uterine bleeding through closing stomachache , wei lump in the abdomen knot; Headache due to deficiency of blood, dizzy, impotence numbness; Intestines are hot-tempered just difficult, and are heavy after the dysentery characterized by blood in the stool, ulcer sores, traumatic injury; Select for use zaocys dhumnade to be because its nature and flavor are sweet, flat, return Liver Channel, dispelling wind and removing obstruction in the meridians is arranged, the function that arresting convulsion relieves the pain cures mainly rheumatoid arthritis stubborn, numbness contracture, the apoplexy deviation of the eye and mouth, hemiplegia, the tic spasm, lockjaw disease, the leprosy mange, scrofula is disliked sore.
In order to obtain optimum curative effect, the present invention also adds egg on the said medicine basis, and this is because egg has another name called Ovum Gallus domesticus, ovum gallinaceum, and nature and flavor are sweet flat; Function nourshing Yin and drynsessmoistening prescription, nourishing blood and preventing abortion is arranged, control the calentura unhappiness, make an uproar and cough celostomia, the conjunctival congestion pharyngalgia; Frequent fetal movement, puerperal, mouth was drunk, and dysentery is scalded; This 7 flavor medicine is made up, and benefiting blood and regulating blood circulation promotes the production of body fluid that it is stronger to hold back the skin ulcer effect, and the curative effect of treatment gastropathy, gastric ulcer, stomachache, pharyngitis is best.
The consumption of drug component of the present invention also is that the inventor gropes to sum up to draw in a large number, and the consumption of each component all has curative effect preferably in following weight range.
Radix Aconiti Preparata head 6-15 restrains Fructus Mume 6-15 gram Radix Glycyrrhizae 6-15 gram
Radix Aconiti Kusnezoffii Preparata head 6-15 gram Radix Angelicae Sinensis 6-15 gram Zaocys 6-15 gram
System egg 30-40 gram Chinese liquor 900-1200 gram
Preferable amount is:
Radix Aconiti Preparata head 9 is restrained Fructus Mume 9 gram Radix Glycyrrhizaes 9 grams
Radix Aconiti Kusnezoffii Preparata head 9 gram Radix Angelicae Sinensis 9 gram Zaocyss 9 grams
System egg 35 gram Chinese liquor 1000 grams
Method for preparing of the present invention is following, and it comprises the following steps:
One, gets the raw materials ready
1, Radix Aconiti Preparata head: get clean Radix Aconiti, soak with cold water and float, change water 2-3 every day, floats to taste to mouth and take out when only staying spicy sense slightly; Same Radix Glycyrrhizae, Semen sojae atricolor add water and decoct altogether, and be well-done to Radix Aconiti, interior no Bai Xinwei degree; Remove Radix Glycyrrhizae, Semen sojae atricolor, dry in the sun is cut into slices behind the moistening; Dry (100 jin of every Radix Aconitis, with 5 jin in Radix Glycyrrhizae, 10 jin in Semen sojae atricolor);
2, system Fructus Mume: get clean Fructus Mume and fry with high heat to skin and flesh and heave, shrivelled speckle occurs and be degree, water spray dries, and taking-up cools;
3, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when eighty per cant passes through, pull out, run through section, dry;
4, Radix Aconiti Kusnezoffii Preparata head: get clean Radix Aconiti Kusnezoffii, soak with cold water and float, change water 2-3 every day; Taste to mouth and to take out when only staying spicy sense slightly, same Radix Glycyrrhizae, Semen sojae atricolor add water and boil altogether, with well-done, the interior no Bai Xinwei degree of Radix Aconiti Kusnezoffii; Remove Radix Glycyrrhizae and Semen sojae atricolor then, shine to sixty percent and do, cut into slices behind the moistening; Dry (100 jin of every Radix Aconiti Kusnezoffii, with 5 jin in Radix Glycyrrhizae, 10 jin in Semen sojae atricolor);
5, Radix Angelicae Sinensis: choose decontamination, clean, moistening, when cold to internal and external temperature was suitable slightly, section was dried;
6, Zaocys: get crude drug, brush away the ash bits, decaptitate squama, cutting;
7, system egg: break eggshell, take out Ovum Gallus domesticus album, egg yolk is placed in the iron pan and is baked into coke yellow;
8, Chinese liquor: choose 52 degree Sorghum vulgare Pers. Chinese liquor.
Two, preparation
1, puts into container by measuring foot 52 degree Sorghum vulgare Pers. Chinese liquor;
2, Radix Aconiti Preparata head, system Fructus Mume, Radix Glycyrrhizae, Radix Aconiti Kusnezoffii Preparata head, Radix Angelicae Sinensis, Zaocys are put into the container of depositing Sorghum vulgare Pers. Chinese liquor jointly together with the good egg of roasting;
3, seal immersion 7-10 days;
4, the time spent shakes up.
Medicine of the present invention has clearing away heat-fire, detoxifcation, antiinflammatory, removing heat from blood and holds back functions such as skin ulcer, is used to treat diseases such as gastropathy, gastric ulcer, stomachache, abdominal distention, chronic pharyngitis, pelvic inflammatory disease, arthritis, scapulohumeral periarthritis, lumbar muscle strain and lumbago and skelalgia, and curative effect is fast, and cure rate is high.
Below come further to set forth the beneficial effect of medicine of the present invention, these Test Example to comprise that the animal experiment of medicine of the present invention and clinical observation on the therapeutic effect test through Test Example.
[Test Example 1]
The therapeutical effect of rabbit oral ulcer due to medicine of the present invention (the to call BAIYAO wine in the following text) Dichlorodiphenyl Acetate.
Get 20 of new zealand rabbits, male and female dual-purpose, body weight 2.0-2.5kg; Cotton swab with being immersed in the acetic acid is pressed in the middle modeling in about 15 seconds of rabbit tongue, and the diameter 5mm of mucosa ulcer is divided into 2 groups with rabbit after the modeling; Every group 10, wherein one group is the treatment group of using medicine of the present invention, and another group is for using the matched group of peers hydrops; getting 100 milliliters of BAIYAO wine of the present invention is used for the treatment group, and other gets 100 milliliters of matched groups that are used for comparison of plain boiled water, and administering mode is a gastric infusion; once a day, serve on 10 days, observes medicining condition every day.
Form white ulcer after the rabbit modeling, white secretions occurred in second day, viewing duration, the obvious unnecessary treatment group of matched group rabbit white secretions, the beginning in the 3rd day of treatment group secretions obviously reduces, and the ulcer area obviously dwindles.After 10 days, dead 1 of 10 rabbit of matched group, 1 of rotten to the corn pathological changes, all the other 8 ulcer areas increase to 32.7, and the treatment group is all cured by 10 rabbit.The result shows: BAIYAO wine of the present invention is given the treatment comparison of treatment group with matched group, and the Peptic Ulcers due to the Dichlorodiphenyl Acetate has the obvious treatment effect.
[Test Example 2]
The clinical treatment observation data of medicine of the present invention.
1, physical data
Accept out-patient's totally 317 examples for medical treatment, wherein male 196 examples, women 121 examples, age 1-10 year 83 people wherein, 11-20 year 78 people, 21-30 year 29 people, 31-40 year 35 people, 41-50 year 37 people, 55 people more than 50 years old.
2, diagnostic criteria
Gastropathy, gastric ulcer and stomachache, clinical manifestation uncomfortable in chest are patient gastric area pain, loss of appetite, poor appetite, during outbreak with the nausea and vomiting symptom, the microscopy stool blood.
Chronic pharyngitis is the chronic inflammatory disease of pharyngeal mucosa, and with pharyngeal discomfort, dry, it is characteristic that foreign body sensation or mild pain are arranged, and shows as dry cough, feels sick, and pharyngeal congestion is kermesinus, the visible lymph follicle of pharynx rear wall.
Arthritis, scapulohumeral periarthritis, pelvic inflammatory disease, lumbar muscle strain and lumbago and skelalgia to show as the movable positions of whole bodies such as shoulder around the extremities joint, cervical region, waist, rear spine portion local or single limb joint whole show is limited; Pain or pressurized pain; The patient can not walk, and can not stand when serious.
3, Therapeutic Method
Ante cibum in the morning (medicine) being taken before meal usefulness, once-a-day, each 3-5 milliliter, after three days every day secondary, each 5-8 milliliter, 10 is a course of treatment, serve on the 2-3 course of treatment.
4, efficacy assessment standard
Produce effects: gastropathy, gastric ulcer, stomachache, pharyngitis and various arthritis, after 2-3 course of therapy, the stomach ulcer healing, pharyngeal and joint, spinal column recover normal, and pelvic inflammatory disease takes effect after oral 10 hours, observes 1 year no recidivist.
Take a turn for the better: gastropathy, gastric ulcer, stomachache, pharyngitis and various arthritis, stomach pain relief after treatment, appetite takes a turn for the better, and stool blood is negative, and is pharyngeal dry, and foreign body sensation disappears; Extremities joint and shoulder, neck, lumbar vertebrae pain alleviate, the basic recovery normally.
Invalid: as not reach improvement standard person.
5, therapeutic outcome (seeing the following form)
Figure GSA00000023634100051
In an above-mentioned 2-3 course of therapy, with Drug therapy gastropathy of the present invention, gastric ulcer, stomachache, patient uncomfortable in chest 156 examples, produce effects 139 examples as a result, 10 examples that take a turn for the better, invalid 7 examples, obvious effective rate is 89.10%, and improvement rate is 6.41%, and total effective rate is 95.51%.Treatment chronic pharyngitis patient 32 examples, produce effects 28 examples as a result, 3 examples that take a turn for the better, invalid 1 example, obvious effective rate is 87.50%, and improvement rate is 9.38%, and total effective rate is 96.88%.Treatment of arthritis, scapulohumeral periarthritis, pelvic inflammatory disease, lumbar muscle strain, lumbago and skelalgia patient 129 examples, produce effects 107 examples as a result, 12 examples that take a turn for the better, invalid 10 examples, obvious effective rate is 82.95%, total effective rate is 92.25%.

Claims (3)

1. medicine of treating gastropathy, gastric ulcer, stomachache, uncomfortable in chest, chronic pharyngitis, it is characterized in that: it is to be processed by the crude drug in the following weight scope:
Radix Aconiti Preparata head 6-15 restrains Fructus Mume 6-15 gram Radix Glycyrrhizae 6-15 gram
Radix Aconiti Kusnezoffii Preparata head 6-15 gram Radix Angelicae Sinensis 6-15 gram Zaocys 6-15 gram
System egg 30-40 gram Chinese liquor 900-1200 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Radix Aconiti Preparata head 9 is restrained Fructus Mume 9 gram Radix Glycyrrhizaes 9 grams
Radix Aconiti Kusnezoffii Preparata head 9 gram Radix Angelicae Sinensis 9 gram Zaocyss 9 grams
System egg 35 gram Chinese liquor 1000 grams.
3. the method for preparing of medicine according to claim 1 and 2, it is characterized in that: it comprises the following steps:
(1) gets the raw materials ready
(1) Radix Aconiti Preparata head: get clean Radix Aconiti, soak with cold water and float, change water 2-3 every day, floats to taste to mouth and take out when only staying spicy sense slightly; Same Radix Glycyrrhizae, Semen sojae atricolor add water and decoct altogether, and be well-done to Radix Aconiti, and interior no Bai Xinwei degree is removed Radix Glycyrrhizae, Semen sojae atricolor; Dry in the sun is cut into slices behind the moistening, dries; 100 jin of every Radix Aconitis, with 5 jin in Radix Glycyrrhizae, 10 jin in Semen sojae atricolor;
(2) system Fructus Mume: get clean Fructus Mume and fry with high heat to skin and flesh and heave, shrivelled speckle occurs and be degree, water spray dries, and taking-up cools;
(3) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water when eighty per cant passes through, pull out, run through section, dry;
(4) Radix Aconiti Kusnezoffii Preparata head: get clean Radix Aconiti Kusnezoffii, soak with cold water and float, change water every day 2~3 times, taste to mouth and take out when only staying spicy sense slightly; Same Radix Glycyrrhizae, Semen sojae atricolor add water and boil altogether, with well-done, the interior no Bai Xinwei degree of Radix Aconiti Kusnezoffii, remove Radix Glycyrrhizae and Semen sojae atricolor then; Solarization to sixty percent is done, and cuts into slices behind the moistening, dries; 100 jin of every Radix Aconiti Kusnezoffii, with 5 jin in Radix Glycyrrhizae, 10 jin in Semen sojae atricolor;
(5) Radix Angelicae Sinensis: choose decontamination, clean, moistening, when cold to internal and external temperature was suitable slightly, section was dried;
(6) Zaocys: get crude drug, brush away the ash bits, decaptitate squama, cutting;
(7) system egg: break eggshell, take out Ovum Gallus domesticus album, egg yolk is placed in the iron pan and is baked into coke yellow;
(8) Chinese liquor: choose 52 degree Sorghum vulgare Pers. Chinese liquor;
(2) preparation
(1) puts into container by measuring foot 52 degree Sorghum vulgare Pers. Chinese liquor;
(2) Radix Aconiti Preparata head, system Fructus Mume, Radix Glycyrrhizae, Radix Aconiti Kusnezoffii Preparata head, Radix Angelicae Sinensis, Zaocys are put into the container of depositing Sorghum vulgare Pers. Chinese liquor jointly together with the good egg of roasting;
(3) seal immersion 7-10 days;
(4) time spent shakes up.
CN2010101069114A 2010-02-08 2010-02-08 Drug for treating gastropathy, gastric ulcer, abdominal pain, chest distress and chronic pharyngitis, and preparation method thereof Expired - Fee Related CN102018788B (en)

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CN102994335A (en) * 2012-10-18 2013-03-27 张翼飞 Medicinal liquor for nourishing and warming stomach
CN105194071A (en) * 2015-11-03 2015-12-30 孙太辉 Medicine for treating chondromalacia patellae and preparation method of medicine
CN114949153A (en) * 2022-03-28 2022-08-30 江苏莹华生物制药有限公司 Aconitum carmichaeli decoction oral granules for treating arthritis and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1050683A (en) * 1990-10-11 1991-04-17 张化文 A kind of specific medicine for neuralgia, arthralgia, poliomyelitis sequel
CN1179962A (en) * 1997-05-12 1998-04-29 郭正元 Traditional Chinese medicine preparation for curing rheumatism and its preparing method
CN1181245A (en) * 1996-11-01 1998-05-13 唐山钢铁集团有限责任公司 Method for preparing zaocys dhumnade bone health pill (powder)
CN1280847A (en) * 1999-07-20 2001-01-24 白桂林 Preparation method of medicinal liquor for treating rheumatic arthritis
CN1660161A (en) * 2004-02-27 2005-08-31 王继喜 Combination of Chinese traditional medicine for treating rheumatism, and preparation method and application

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1050683A (en) * 1990-10-11 1991-04-17 张化文 A kind of specific medicine for neuralgia, arthralgia, poliomyelitis sequel
CN1181245A (en) * 1996-11-01 1998-05-13 唐山钢铁集团有限责任公司 Method for preparing zaocys dhumnade bone health pill (powder)
CN1179962A (en) * 1997-05-12 1998-04-29 郭正元 Traditional Chinese medicine preparation for curing rheumatism and its preparing method
CN1280847A (en) * 1999-07-20 2001-01-24 白桂林 Preparation method of medicinal liquor for treating rheumatic arthritis
CN1660161A (en) * 2004-02-27 2005-08-31 王继喜 Combination of Chinese traditional medicine for treating rheumatism, and preparation method and application

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