CN102688382B - Gamene oral liquid for treating acute gastroenteritis and preparation method thereof - Google Patents
Gamene oral liquid for treating acute gastroenteritis and preparation method thereof Download PDFInfo
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- CN102688382B CN102688382B CN 201210204449 CN201210204449A CN102688382B CN 102688382 B CN102688382 B CN 102688382B CN 201210204449 CN201210204449 CN 201210204449 CN 201210204449 A CN201210204449 A CN 201210204449A CN 102688382 B CN102688382 B CN 102688382B
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- 239000007788 liquid Substances 0.000 title claims abstract description 42
- 208000005577 Gastroenteritis Diseases 0.000 title claims abstract description 16
- 208000012873 acute gastroenteritis Diseases 0.000 title claims abstract description 15
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- JLYXXMFPNIAWKQ-UHFFFAOYSA-N γ Benzene hexachloride Chemical compound ClC1C(Cl)C(Cl)C(Cl)C(Cl)C1Cl JLYXXMFPNIAWKQ-UHFFFAOYSA-N 0.000 title abstract 4
- 239000003814 drug Substances 0.000 claims abstract description 28
- 229940079593 drug Drugs 0.000 claims abstract description 8
- 238000009835 boiling Methods 0.000 claims description 20
- 241000628997 Flos Species 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 238000010438 heat treatment Methods 0.000 claims description 6
- 238000004821 distillation Methods 0.000 claims description 5
- 238000002156 mixing Methods 0.000 claims description 5
- 239000006228 supernatant Substances 0.000 claims description 5
- 206010012735 Diarrhoea Diseases 0.000 abstract description 11
- 206010047700 Vomiting Diseases 0.000 abstract description 10
- 230000008673 vomiting Effects 0.000 abstract description 10
- 230000035876 healing Effects 0.000 abstract description 2
- 208000004998 Abdominal Pain Diseases 0.000 abstract 1
- 241001529821 Agastache Species 0.000 abstract 1
- 241000928504 Centipeda minima Species 0.000 abstract 1
- 244000035851 Chrysanthemum leucanthemum Species 0.000 abstract 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 abstract 1
- 241001633680 Polygonatum odoratum Species 0.000 abstract 1
- 241001162994 Rugosus Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 abstract 1
- 235000007212 Verbena X moechina Moldenke Nutrition 0.000 abstract 1
- 240000001519 Verbena officinalis Species 0.000 abstract 1
- 235000001594 Verbena polystachya Kunth Nutrition 0.000 abstract 1
- 235000007200 Verbena x perriana Moldenke Nutrition 0.000 abstract 1
- 235000002270 Verbena x stuprosa Moldenke Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 8
- 230000037213 diet Effects 0.000 description 7
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- 210000004185 liver Anatomy 0.000 description 5
- 210000004072 lung Anatomy 0.000 description 5
- 230000001976 improved effect Effects 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
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- 206010007247 Carbuncle Diseases 0.000 description 1
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- 230000001142 anti-diarrhea Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
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- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
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Abstract
The invention discloses a gamene oral liquid for treating acute gastroenteritis and a preparation method of the gamene oral liquid. The oral liquid is prepared by the following bulk drugs in parts by weight: 100-260 parts of gamene, 100-260 parts of wild chrysanthemum, 100-140 parts of dandelion, 100-140 parts of verbena, 100-140 parts of centipeda minima, 100-260 parts of agastache rugosus and 100-140 parts of polygonatum odoratum. The oral liquid provided by the invention can be used for treating vomiting, abdominal pain and diarrhea caused by acute gastroenteritis; the healing effect is good and the oral liquid is worth for clinical promotion and application.
Description
Technical field
The invention belongs to the field of Chinese medicines, particularly a kind of acute gastroenteritis Radix Rubiae Chinese medicine oral liquid and preparation method for the treatment of.
Background technology
Acute gastroenteritis is the acute inflammation of gastrointestinal mucosa, and that clinical manifestation is mainly is nauseating, vomiting, stomachache, diarrhoea, heating etc.Primary disease is common in summer and autumn, and it takes place many owing to improper diet, eating and drinking too much at one meal; Or eat that raw food rotten is turned sour, foul unclean food.The traditional Chinese medical science is according to the difference of the cause of disease and body constitution, and gastroenteritis is divided into damp and hot, cold-damp and stagnant etc. dissimilar.At present, the medicine that is used for the treatment of acute gastroenteritis has many kinds, because Chinese patent medicine has little, the eutherapeutic characteristics of side effect, so favored by people.
Summary of the invention
The invention provides little, the good effect of a kind of toxic and side effects, be used for the treatment of acute gastroenteritis Radix Rubiae Chinese medicine oral liquid and preparation method.
For achieving the above object, the present invention is achieved by the following technical solutions:
Treatment acute gastroenteritis Radix Rubiae Chinese medicine oral liquid is to be made by the crude drug of following parts by weight:
Radix Rubiae 100-260 part, Flos Chrysanthemi Indici 100-260 part, Herba Taraxaci 100-140 part, Herba Verbenae 100-140 part, Herba Centipedae 100-140 part, Herba Pogostemonis 100-260 part, Rhizoma Polygonati Odorati 100-140 part.
Described treatment acute gastroenteritis Radix Rubiae Chinese medicine oral liquid is to be made by the crude drug of following parts by weight:
180 parts in Radix Rubiae, 180 parts of Flos Chrysanthemi Indicis, 120 parts of Herba Taraxacis, 120 parts of Herba Verbenae, 120 parts of Herba Centipedae, 180 parts of Herba Pogostemoniss, 120 parts of Rhizoma Polygonati Odorati.
Described treatment acute gastroenteritis Radix Rubiae Chinese medicine oral liquid and preparation method comprise the following steps:
A, get 180 parts in Radix Rubiae, 120 parts of Herba Verbenae, 120 parts of Herba Centipedae, 120 parts of water that add 8 times of Rhizoma Polygonati Odorati, 60-80 ℃ is soaked continuation heating after 30-60 minute down, intense fire boiling 15 minutes, continuation was with slow fire boiling 40-80 minute, filter, separate, get supernatant, be cooled to 30-40 ℃, obtain boiling and carry medicinal liquid A;
B, get 180 parts of Herba Pogostemoniss, 180 parts of Flos Chrysanthemi Indicis, 120 parts of water that add 8 times of Herba Taraxaci, soaked 30-40 minute under the room temperature, distillate is collected in 40-80 ℃ of distillation 50-100 minute, is cooled to 30-40 ℃, obtains the distillate medical liquid B;
C, described boiling are put forward medicinal liquid A and described distillate medical liquid B according to volume ratio 1:1, merge mixing, namely obtain described treatment acute gastroenteritis Radix Rubiae Chinese medicine oral liquid.
Instructions of taking: every day early, middle and late respectively taking once, a dose is l0ml, takes medicine that the back is many took effect at 2-3 days 7 days courses for the treatment of, 1-2 the healing course for the treatment of.This Chinese medicine oral liquid characteristics are that the patient is fully recovered, and effective, toxic and side effects is little, play treating both the principal and secondary aspects of a disease, set upright evil, the eliminating evil positive effect of not hindering that do not stagnate, and do not have recurrence, and cost is low, is worth clinical application.
In the selected raw material of Chinese medicine of the present invention, Radix Rubiae: bitter, cold, return Liver Channel, cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling; Flos Chrysanthemi Indici: bitter, hot, be slightly cold, return lung, Liver Channel, heat-clearing and toxic substances removing; Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp, heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation, eliminating damp-heat; Herba Verbenae: bitter, cool, return liver, spleen channel, promoting blood circulation to remove blood stasis, preventing the attack (or recurrence) of malaria, detoxifcation, inducing diuresis to remove edema; Herba Centipedae: hot, warm, return lung, Liver Channel, dispel the wind, cold expelling wins and wets, removing nebula, stuffy nose relieving plug; Herba Pogostemonis: hot, tepor, return spleen, stomach, lung meridian, eliminating turbid pathogen with aromatics, the appetizing preventing or arresting vomiting is delivered expelling summer-heat; Rhizoma Polygonati Odorati: sweet, flat, attach to the lung and stomach meridians nourishing YIN and moistening the lung, the nourishing the stomach of promoting the production of body fluid; All medicines support to have the function of wind and heat dispersing, subduing swelling and detoxicating, stomach function regulating antidiarrheal, detoxicating, relieving inflammation mutually, and oral liquid of the present invention can be removed vomiting, stomachache, the diarrhea due to the acute gastroenteritis, and is evident in efficacy, are worth clinical application.Points for attention: anemia of pregnant woman's forbidding.
The specific embodiment
EXAMPLE l:
Crude drug: 180 parts in Radix Rubiae, 180 parts of Flos Chrysanthemi Indicis, 120 parts of Herba Taraxacis, 120 parts of Herba Verbenae, 120 parts of Herba Centipedae, 180 parts of Herba Pogostemoniss, 120 parts of Rhizoma Polygonati Odorati.
Method for making: A, get 180 parts in Radix Rubiae, 120 parts of Herba Verbenae, 120 parts of Herba Centipedae, 120 parts of water that add 8 times of Rhizoma Polygonati Odorati, 60-80 ℃ is soaked continuation heating after 30-60 minute down, intense fire boiling 15 minutes, continuation was with slow fire boiling 40-80 minute, filter, separate, get supernatant, cool off 30-40 ℃, obtain boiling and carry medicinal liquid A;
B, get 180 parts of Herba Pogostemoniss, 180 parts of Flos Chrysanthemi Indicis, 120 parts of water that add 8 times of Herba Taraxaci, soaked 30-40 minute under the room temperature, distillate is collected in 40-80 ℃ of distillation 50-100 minute, is cooled to 30-40 ℃, obtains the distillate medical liquid B;
C, described boiling are put forward medicinal liquid A and described distillate medical liquid B according to volume ratio 1:1, merge mixing, namely.
Embodiment 2:
Crude drug: 260 parts in Radix Rubiae, 260 parts of Flos Chrysanthemi Indicis, 140 parts of Herba Taraxacis, 140 parts of Herba Verbenae, 140 parts of Herba Centipedae, 260 parts of Herba Pogostemoniss, 140 parts of Rhizoma Polygonati Odorati.
Method for making: A, get 260 parts in Radix Rubiae, 140 parts of Herba Verbenae, 140 parts of Herba Centipedae, 140 parts of water that add 8 times of Rhizoma Polygonati Odorati, 60-80 ℃ is soaked continuation heating after 30-60 minute down, intense fire boiling 15 minutes, continuation was with slow fire boiling 40-80 minute, filter, separate, get supernatant, cool off 30-40 ℃, obtain boiling and carry medicinal liquid A;
B, get 260 parts of Herba Pogostemoniss, 260 parts of Flos Chrysanthemi Indicis, 140 parts of water that add 8 times of Herba Taraxaci, soaked 30-40 minute under the room temperature, distillate is collected in 40-80 ℃ of distillation 50-100 minute, is cooled to 30-40 ℃, obtains the distillate medical liquid B;
C, described boiling are put forward medicinal liquid A and described distillate medical liquid B according to volume ratio 1:1, merge mixing, namely.
Embodiment 3:
Crude drug: 100 parts in Radix Rubiae, 100 parts of Flos Chrysanthemi Indicis, 100 parts of Herba Taraxacis, 100 parts of Herba Verbenae, 100 parts of Herba Centipedae, 100 parts of Herba Pogostemoniss, 100 parts of Rhizoma Polygonati Odorati.
Method for making: A, get 100 parts in Radix Rubiae, 100 parts of Herba Verbenae, 100 parts of Herba Centipedae, 100 parts of water that add 8 times of Rhizoma Polygonati Odorati, 60-80 ℃ is soaked continuation heating after 30-60 minute down, intense fire boiling 15 minutes, continuation was with slow fire boiling 40-80 minute, filter, separate, get supernatant, cool off 30-40 ℃, obtain boiling and carry medicinal liquid A;
B, get 100 parts of Herba Pogostemoniss, 100 parts of Flos Chrysanthemi Indicis, 100 parts of water that add 8 times of Herba Taraxaci, soaked 30-40 minute under the room temperature, distillate is collected in 40-80 ℃ of distillation 50-100 minute, is cooled to 30-40 ℃, obtains the distillate medical liquid B;
C, described boiling are put forward medicinal liquid A and described distillate medical liquid B according to volume ratio 1:1, merge mixing, namely.
Embodiment 4:
Clinical trial
(1) subjects: adopt the present invention to treat 100 routine patients altogether, male 42 examples wherein, women 58 examples; The oldest person 80 years old, age reckling 15 years old.
(2) Therapeutic Method: every day early, middle and late respectively taking once, a dose is l0ml, 7 days courses for the treatment of.
(3) treatment standard
Cure: vomiting, diarrhoea stop fully, and stool is normal, and diet is normal, and is in high spirits.
Produce effects: vomiting, diarrhoea are significantly improved, and it is normal substantially to defecate, and diet is normal, and is in high spirits.
Effectively: vomiting, diarrhoea are improved, and stool is improved or be normal, and diet improves, and spirit is improved.
Invalid: vomiting, the no any improvement of diarrhoea, lethargy is depressed.
(4) therapeutic outcome: the back of taking medicine in patient's 100 routine cases is many took effect at 2-3 days, and cure 1-2 the course for the treatment of.Wherein cure 70 examples, produce effects 25 examples, effective 3 examples, invalid 2 examples, total effective rate reaches 98%.
Embodiment 5:
Model case: Hu, woman, 27 years old, patient's diet is improper, vomiting twice, sour in the mouth corruption, anorexia, abdominal distention, rare water of defecating was taken the embodiment of the invention 1 Chinese medicine oral liquid 2, abdominal distention alleviates, and vomiting ends, and continues and uses the embodiment of the invention 1 Chinese medicine oral liquid 5 days, stool is normal, diet increases, and spirit takes a turn for the better, and symptom all disappears.
Embodiment 6:
Model case: Xu certain, man, 46 years old, diarrhoea, feces is thin in water sample, namely rushes down that night seven or eight times, next day, diarrhoea was still many, and spiritlessness and weakness was taken the embodiment of the invention 1 Chinese medicine oral liquid 2, diarrhoea decrescence, continue and use the embodiment of the invention 1 Chinese medicine oral liquid 5 days, oneself ends diarrhoea, and borborygmus are not done, diet increases, and spirit is gradually shaken.Continue and use the embodiment of the invention 1 Chinese medicine oral liquid 2 days, patient's recovery from illness.
Claims (1)
1. treat acute gastroenteritis Radix Rubiae Chinese medicine oral liquid for one kind, it is characterized in that: be to be made by the crude drug of following parts by weight:
180 parts in Radix Rubiae, 180 parts of Flos Chrysanthemi Indicis, 120 parts of Herba Taraxacis, 120 parts of Herba Verbenae, 120 parts of Herba Centipedae, 180 parts of Herba Pogostemoniss, 120 parts of Rhizoma Polygonati Odorati; Its preparation process is as follows:
A, get 180 parts in Radix Rubiae, 120 parts of Herba Verbenae, 120 parts of Herba Centipedae, 120 parts of water that add 8 times of Rhizoma Polygonati Odorati, 60-80 ℃ is soaked continuation heating after 30-60 minute down, intense fire boiling 15 minutes, continuation was with slow fire boiling 40-80 minute, filter, separate, get supernatant, be cooled to 30-40 ℃, obtain boiling and carry medicinal liquid A;
B, get 180 parts of Herba Pogostemoniss, 180 parts of Flos Chrysanthemi Indicis, 120 parts of water that add 8 times of Herba Taraxaci, soaked 30-40 minute under the room temperature, distillate is collected in 40-80 ℃ of distillation 50-100 minute, is cooled to 30-40 ℃, obtains the distillate medical liquid B;
C, described boiling are put forward medicinal liquid A and described distillate medical liquid B according to volume ratio 1:l, merge mixing, namely obtain described treatment acute gastroenteritis Radix Rubiae Chinese medicine oral liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 201210204449 CN102688382B (en) | 2012-06-19 | 2012-06-19 | Gamene oral liquid for treating acute gastroenteritis and preparation method thereof |
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| CN 201210204449 CN102688382B (en) | 2012-06-19 | 2012-06-19 | Gamene oral liquid for treating acute gastroenteritis and preparation method thereof |
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| Publication Number | Publication Date |
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| CN102688382A CN102688382A (en) | 2012-09-26 |
| CN102688382B true CN102688382B (en) | 2013-09-04 |
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Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1418664A (en) * | 2002-11-25 | 2003-05-21 | 郁建生 | Lireqing injecta (for clearing heat and diminishing inflammation) |
| CN1498651A (en) * | 2002-11-07 | 2004-05-26 | 廖光荣 | Medicaton for treating celiaca and its prepn. method |
| CN101537156A (en) * | 2009-01-22 | 2009-09-23 | 曹莹莹 | Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease |
| CN101984994A (en) * | 2010-09-25 | 2011-03-16 | 珠海圣原生物科技有限公司 | Medicament for improving human intestinal flora balance and preparation method thereof |
| CN102266514A (en) * | 2011-07-06 | 2011-12-07 | 曹明成 | Chinese medicinal composition for treating acute and chronic gastritis and preparation method thereof |
| CN102362906A (en) * | 2011-10-03 | 2012-02-29 | 周春根 | Traditional Chinese medicine for treating acute enteritis |
-
2012
- 2012-06-19 CN CN 201210204449 patent/CN102688382B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1498651A (en) * | 2002-11-07 | 2004-05-26 | 廖光荣 | Medicaton for treating celiaca and its prepn. method |
| CN1418664A (en) * | 2002-11-25 | 2003-05-21 | 郁建生 | Lireqing injecta (for clearing heat and diminishing inflammation) |
| CN101537156A (en) * | 2009-01-22 | 2009-09-23 | 曹莹莹 | Chinese herbal medicine composite capable of curing stomach illness and duodenal ulcer disease |
| CN101984994A (en) * | 2010-09-25 | 2011-03-16 | 珠海圣原生物科技有限公司 | Medicament for improving human intestinal flora balance and preparation method thereof |
| CN102266514A (en) * | 2011-07-06 | 2011-12-07 | 曹明成 | Chinese medicinal composition for treating acute and chronic gastritis and preparation method thereof |
| CN102362906A (en) * | 2011-10-03 | 2012-02-29 | 周春根 | Traditional Chinese medicine for treating acute enteritis |
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