CN102015692A - 丙型肝炎病毒抑制剂 - Google Patents

丙型肝炎病毒抑制剂 Download PDF

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Publication number
CN102015692A
CN102015692A CN2009801137102A CN200980113710A CN102015692A CN 102015692 A CN102015692 A CN 102015692A CN 2009801137102 A CN2009801137102 A CN 2009801137102A CN 200980113710 A CN200980113710 A CN 200980113710A CN 102015692 A CN102015692 A CN 102015692A
Authority
CN
China
Prior art keywords
cap
alkyl
hcv
compound
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2009801137102A
Other languages
English (en)
Chinese (zh)
Inventor
C·巴查德
B·马科宁
D·H·戴昂
A·C·古德
J·古瑞奇
C·A·詹姆斯
R·拉威
O·D·洛裴兹
A·马特尔
N·A·米恩威尔
V·N·恩古颜
J·L·洛明
E·H·鲁迪格
L·B·辛德
D·R·圣罗伦
杨福康
D·R·兰利
王敢
L·G·哈曼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of CN102015692A publication Critical patent/CN102015692A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
CN2009801137102A 2008-02-12 2009-02-10 丙型肝炎病毒抑制剂 Pending CN102015692A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2801108P 2008-02-12 2008-02-12
US61/028011 2008-02-12
PCT/US2009/033646 WO2009102694A1 (en) 2008-02-12 2009-02-10 Heterocyclic derivatives as hepatitis c virus inhibitors

Publications (1)

Publication Number Publication Date
CN102015692A true CN102015692A (zh) 2011-04-13

Family

ID=40524712

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009801137102A Pending CN102015692A (zh) 2008-02-12 2009-02-10 丙型肝炎病毒抑制剂

Country Status (11)

Country Link
US (1) US8093243B2 (enExample)
EP (1) EP2242751B1 (enExample)
JP (1) JP2011511841A (enExample)
KR (1) KR20100123717A (enExample)
CN (1) CN102015692A (enExample)
AU (1) AU2009214977A1 (enExample)
BR (1) BRPI0907733A2 (enExample)
CA (1) CA2715400A1 (enExample)
IL (1) IL207470A0 (enExample)
MX (1) MX2010008699A (enExample)
WO (1) WO2009102694A1 (enExample)

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US20110274648A1 (en) 2009-11-11 2011-11-10 Bristol-Myers Squibb Company Hepatitis C Virus Inhibitors
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EP2512480A4 (en) 2009-12-14 2013-05-15 Enanta Pharm Inc HEPATITIS C-VIRUS HEMMER
US8377980B2 (en) 2009-12-16 2013-02-19 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
CA2784748A1 (en) 2009-12-18 2011-06-23 Idenix Pharmaceuticals, Inc. 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
US8362020B2 (en) 2009-12-30 2013-01-29 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8933110B2 (en) 2010-01-25 2015-01-13 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
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US8178531B2 (en) 2010-02-23 2012-05-15 Enanta Pharmaceuticals, Inc. Antiviral agents
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EP2575819A4 (en) 2010-06-04 2013-11-27 Enanta Pharm Inc INHIBITORS OF HEPATITIS C VIRUS
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Also Published As

Publication number Publication date
US20090233925A1 (en) 2009-09-17
IL207470A0 (en) 2010-12-30
AU2009214977A1 (en) 2009-08-20
EP2242751A1 (en) 2010-10-27
EP2242751B1 (en) 2015-07-15
US8093243B2 (en) 2012-01-10
BRPI0907733A2 (pt) 2015-07-14
CA2715400A1 (en) 2009-08-20
KR20100123717A (ko) 2010-11-24
WO2009102694A1 (en) 2009-08-20
MX2010008699A (es) 2010-08-30
JP2011511841A (ja) 2011-04-14

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Application publication date: 20110413