CN102014623A - 使用聚酮化物合酶制备生物燃料 - Google Patents

使用聚酮化物合酶制备生物燃料 Download PDF

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Publication number
CN102014623A
CN102014623A CN200980115223XA CN200980115223A CN102014623A CN 102014623 A CN102014623 A CN 102014623A CN 200980115223X A CN200980115223X A CN 200980115223XA CN 200980115223 A CN200980115223 A CN 200980115223A CN 102014623 A CN102014623 A CN 102014623A
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China
Prior art keywords
lactone
composition
pks
carboxylic acid
host cell
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Pending
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CN200980115223XA
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English (en)
Chinese (zh)
Inventor
莱昂纳德·卡茨
杰弗里·L·福特曼
杰伊·D·科斯林
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University of California San Diego UCSD
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University of California San Diego UCSD
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Publication of CN102014623A publication Critical patent/CN102014623A/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/08—Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN200980115223XA 2008-04-29 2009-04-29 使用聚酮化物合酶制备生物燃料 Pending CN102014623A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4881708P 2008-04-29 2008-04-29
US61/048,817 2008-04-29
PCT/US2009/042132 WO2009134899A2 (en) 2008-04-29 2009-04-29 Producing biofuels using polyketide synthases

Publications (1)

Publication Number Publication Date
CN102014623A true CN102014623A (zh) 2011-04-13

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CN200980115223XA Pending CN102014623A (zh) 2008-04-29 2009-04-29 使用聚酮化物合酶制备生物燃料

Country Status (6)

Country Link
US (1) US8420833B2 (https=)
EP (1) EP2268828A4 (https=)
JP (1) JP2011519860A (https=)
CN (1) CN102014623A (https=)
BR (1) BRPI0909059A2 (https=)
WO (1) WO2009134899A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023093810A1 (zh) * 2021-11-25 2023-06-01 上海科技大学 一种聚酯高分子化合物及其制备方法和应用

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012050931A2 (en) * 2010-09-28 2012-04-19 The Regents Of The University Of California Producing alpha-olefins using polyketide synthases
US8852902B2 (en) * 2010-11-22 2014-10-07 The Regents Of The University Of California Producing a trimethylpentanoic acid using hybrid polyketide synthases
US9096859B2 (en) 2011-01-26 2015-08-04 The Regents Of The University Of California Microbial conversion of plant biomass to advanced biofuels
DE102011110946A1 (de) 2011-08-15 2016-01-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von omegafunktionalisierten Carbonsäuren und Carbonsäure-Estern aus einfachen Kohlenstoffquellen
DE102011110945A1 (de) 2011-08-15 2013-02-21 Evonik Degussa Gmbh Biotechnologisches Syntheseverfahren von organischen Verbindungen mit alkIL-Genprodukt
DE102012013969B4 (de) * 2012-07-13 2017-09-14 Oxea Gmbh Verfahren zur Herstellung eines Gemisches stellungsisomerer aliphatischer Isononansäuren ausgehend von 2-Ethylhexanol
US10233431B2 (en) 2014-02-26 2019-03-19 The Regents Of The University Of California Producing 3-hydroxycarboxylic acid and ketone using polyketide synthases
WO2017011407A2 (en) * 2015-07-10 2017-01-19 The Regents Of The University Of California Producing adipic acid and related compounds using hybrid polyketide synthases
EP3824071A4 (en) 2018-07-17 2022-04-20 Conagen Inc. BIOSYNTHETIC MANUFACTURE OF GAMMA LACTONES
US20210062178A1 (en) 2019-06-21 2021-03-04 The Regents Of The University Of California Novel xylose isomerase gene and polypeptide and uses thereof
US12241104B2 (en) 2020-04-01 2025-03-04 The Regents Of The University Of California Use of metal salts and deep eutectic solvents in a process to solubilize a biomass
US12392085B2 (en) 2020-04-28 2025-08-19 The Regents Of The University Of California Use of in-situ ionic liquid (IL) and deep eutectic solvent (DES) synthesis using chemically synthesized or biomass-derived ions in the pretreatment of biomass
US12371855B2 (en) 2020-04-28 2025-07-29 The Regents Of The University Of California Use of ensiled biomass for increased efficiency of the pretreatment of biomass
WO2021226415A1 (en) * 2020-05-07 2021-11-11 The Regents Of The University Of California Delta lactones through engineered polyketide synthases
US12098171B2 (en) 2020-12-11 2024-09-24 The Regents Of The University Of California Hybrid sugar transporters with altered sugar transport activity and uses thereof
US11884620B2 (en) 2020-12-11 2024-01-30 The Regents Of The University Of California Use of polyamines in the pretreatment of biomass
US20240052133A1 (en) 2022-08-05 2024-02-15 The Regents Of The University Of California Chemical recyling of plastics using ionic liquids or deep eutectic solvents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4948924B1 (https=) 1970-05-19 1974-12-24 Mitsubishi Chem Ind
US5234719A (en) * 1991-06-04 1993-08-10 Ecolab Inc. Food additive sanitizing compositions
US5672491A (en) * 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
US5712146A (en) 1993-09-20 1998-01-27 The Leland Stanford Junior University Recombinant combinatorial genetic library for the production of novel polyketides
WO1998049315A2 (en) * 1997-04-30 1998-11-05 Kosan Biosciences, Inc. Combinatorial polyketide libraries produced using a modular pks gene cluster as scaffold
ES2164713T3 (es) 1993-09-20 2002-03-01 Univ Leland Stanford Junior Produccion recombinante de nuevos poliquetidos.
IL122859A0 (en) 1995-07-06 1998-08-16 Univ Leland Stanford Junior Cell-free synthesis of polyketides
GB9814006D0 (en) 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
NZ511722A (en) 1998-11-20 2004-05-28 Kosan Biosciences Inc Recombinant methods and materials for producing epothilone and epothilone derivatives
EP1167362B1 (en) 2000-06-19 2005-05-25 Givaudan SA Fragance precursors
US6639089B2 (en) 2000-11-08 2003-10-28 Soda Aromatic Co., Ltd. Anticancer agents, perfumes or foods and drinks
DE102004042102A1 (de) * 2004-08-30 2006-03-09 GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) Verfahren zur regio-selektiven Oxidation
US7927845B2 (en) * 2006-05-08 2011-04-19 Suntory Holdings Limited Fatty acid synthetase, polynucleotide encoding the same, and uses thereof
US8569023B2 (en) 2008-03-28 2013-10-29 The Regents Of The University Of California Producing dicarboxylic acids using polyketide synthases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023093810A1 (zh) * 2021-11-25 2023-06-01 上海科技大学 一种聚酯高分子化合物及其制备方法和应用

Also Published As

Publication number Publication date
US8420833B2 (en) 2013-04-16
EP2268828A4 (en) 2012-08-01
JP2011519860A (ja) 2011-07-14
WO2009134899A2 (en) 2009-11-05
EP2268828A2 (en) 2011-01-05
WO2009134899A3 (en) 2009-12-30
US20110021790A1 (en) 2011-01-27
BRPI0909059A2 (pt) 2019-09-24

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Application publication date: 20110413