CN102004144A - Micropore check board frame - Google Patents
Micropore check board frame Download PDFInfo
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- CN102004144A CN102004144A CN2009101700842A CN200910170084A CN102004144A CN 102004144 A CN102004144 A CN 102004144A CN 2009101700842 A CN2009101700842 A CN 2009101700842A CN 200910170084 A CN200910170084 A CN 200910170084A CN 102004144 A CN102004144 A CN 102004144A
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- grillage
- positioning boss
- reaction cup
- check
- board frame
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to a micropore check board frame, and belongs to an experimental consumable for a medical test. The micropore check board frame comprises an outer frame of a flat rectangular board frame and a positioning boss, and is characterized in that: the bottom surface of the flat rectangular board frame is a flat surface; the positioning boss stretching towards the inside of a board is arranged in a lining of the board frame; the positioning boss has a double elliptic cylinder structure and is in interference fit with a reaction cup; the bottom flat surface of the board frame provides a positioning surface, so that the lower end of the wall of the reaction cup in interference fit with the positioning boss is completely pressed against the bottom of the board frame; and the periphery of the positioning boss is provided with liquid discharging process holes for discharging overflowing liquid in the experiment operation process. The micropore check board frame is made of polystyrene and is manufactured by a one-time compression molding method; and due to the unique design of the double elliptic cylinder structure of an inner cavity and an outer wall of the positioning boss, the micropore check board frame has the advantage of high stability, can be flexibly assembled and disassembled, is suitable for mass production, and can be used for various experiment operation processes of the medical test.
Description
Technical field
The present invention relates to a kind of medical test experiment consumptive material, the micropore check grillage that particularly a kind of medical test is used.
Background technology
The micropore check grillage that is used for the biology sample detection reaction at present, various ways is arranged to meet the different needs, as 96 fixed microwell plates, the micropore lath of 8 townhouses or 12 townhouses, and cup hole pillar surround the reaction cup hole form one with the be nested micropore inspection panel of syntype of the tubbiness that reacts wall of cup, at present in common chemistry, biology, pharmaceutical field, application arranged all, especially particularly common in the related experiment of a small amount of sample of analysis and research.Progress along with development in science and technology and biomedical technology, requirement to the performance of testing instruments and speed is more and more higher, this has just impelled the continual renovation of testing instruments to regenerate to satisfy the demand that modern clinical examination increases day by day, generation along with new instrument, existing microwell plate can not satisfy the needs that instrument uses gradually, also demonstrate various inconveniences in its use, use such as fixed plate and cause the waste consumptive material easily; The micropore lath of 8 townhouses or 12 townhouses, what simple mobile lath caused behind the application of sample easily overturns, and drop, and sample rocks detecting the labile factors such as influence of data; Even the detachable cup hole pillar that produced afterwards surrounds the be nested micropore check grillage of syntype of the tubbiness in reaction cup hole, the tight reaction cup of card is also arranged, be difficult for placing steadily, shortcoming such as come off in the use easily.
Summary of the invention
At above-mentioned field, the present invention overcomes the deficiency that existing micropore inspection panel exists, a kind of micropore check grillage is provided, its material is a polystyrene, adopt the one-time formed preparation method of mold pressing to make, have use flexibly, firm, convenient, can satisfy multiple user demand, the advantage that is easy to make.
A kind of micropore check grillage comprises grillage housing and 48 positioning boss that reaction cup can be installed, and it is characterized in that: the grillage housing is prolate side's shape, and grillage has bielliptic(al) cylindricality positioning boss inside, and the grillage bottom surface is a plane.
Through hole connects on described positioning boss and the grillage baseplane, and direction stretches in plate.
Above-mentioned positioning boss inwall is the right cylinder cylinder, and external wall cross-section is orthogonal bielliptic(al), and outer wall surface is the bielliptic(al) cylindrical structure.
Above-mentioned positioning boss is a hollow structure.
Leave the liquid fabrication hole that looses around the described positioning boss, and run through the grillage baseplane.
Above-mentioned positioning boss bielliptic(al) shape structure is just in time suitable with the reaction cup bottom cavity, and the interference fit that is about 0.15-0.20mm by size connects, and is used to tighten reaction cup.
Described grillage baseplane provides a locating surface, makes should be close to fully with the grillage bottom cup wall of cup lower end after the interference fit, and is at grade, parallel with the grillage baseplane on each reaction cup of having good positioning.
Micropore check grillage provided by the invention, it is the experiment consumptive material that a kind of immune response that is used for medical science, biological field detects, can be used for antigen, antibody sandwich process and semi-automatic medical test, positioning boss and diffusing liquid fabrication hole are arranged on the grillage baseplane, it has been integrated on the basis of existing each function of micropore grillage, has overcome inconvenience and defective in using.Micropore check grillage of the present invention has also increased more advantage, during use, reaction cup can be fastened on micropore check corresponding positioning boss position, grillage baseplane, when carrying out the processed or sample detection of antigen-antibody bag, reaction cup and micropore check grillage can assemble fast, directly be placed on the special instrument and handle or detect, and will reaction cup not take out, use efficient simplification; In addition, when carrying out the detection of single sample or small amount of sample, can select the micropore lath of respective numbers or reaction cup to be assembled on the grillage according to the test sample number detects, inspection panel with respect to the whole plate of existing integral type, because inspection panel provided by the invention can be taken on the reaction cup installing and locating boss of respective numbers as required, therefore, can not waste vacant reaction cup, reduce the waste of consumptive material; Micropore lath with respect to existing 8 townhouses or 12 townhouses, the application of sample back that finishes is placed directly on the instrument together with grillage and detects or carry out corresponding sample preparation, can reduce the labile factor that simple mobile lath causes behind the application of sample like this, be difficult for overturning, drop, and reduce sample and rock detecting the influence of data; The micropore check grillage that the barreled that surrounds with respect to cup hole pillar is nested, the present invention has overcome the tight reaction cup of card, has been difficult for placing steadily, does not have plane of orientation after the placement, the not first-class shortcoming of height after making reaction cup place.
Micropore grillage of the present invention, for fixation reaction cup better, reaction cup stably is fastened on the micropore check grillage, the assembly of fixation reaction cup can be set at the baseplane of grillage housing lead to the hole site, the present invention has preferably designed positioning boss above through hole, these outer wall of boss can be cylindrical, prismatic, bielliptic(al) cylindricality etc., its cardinal principle is that the size design magnitude of interference is about 0.15-0.20mm, just in time adaptive with the reaction cup bottom cavity, positioning boss insertion reaction cup bottom cavity during use, make its location in place, and the chucking reaction cup.Further in order to fix reaction cup more securely, designed the bielliptic(al) cylindricality outer wall of positioning boss, behind bielliptic(al) column type outer wall and the reaction cup bottom cavity fit suitable gap is arranged, like this, under inside and outside tension force effect, can by plasticity deformation takes place, suitably adjust the scale error between positioning boss and reaction cup, thereby make fit more fastening, more stable firmly reaction cup, the reaction cup that fixes is steady, fastening, be convenient to flexible operating, can carry out respective handling or carry out the detection task, discarded behind the complete corresponding operating of reaction cup, only need add new reaction cup just can carry out new detection task.This unique design structure has overcome cylindrical and cylindrical; a cylindrical and prismatic fit require machining precision very high, be easy to produce the shortcoming that fit is crossed pine or tension if any scale error; easier accomplishing scale production, thus make the present invention have more practicality and novelty.
When reaction cup after executing corresponding operating on the microwell plate, this reaction cup then must be discarded, can be by manually reaction cup being taken off from positioning boss, the present invention is designed to a cavity of checking the through hole on the grillage baseplane to connect with micropore on positioning boss, can deliver to reaction cup jack-up from positioning boss again the discarded bucket by through hole with jacking mechanism, like this can be safer.
The positioning boss of micropore check grillage of the present invention mostly is 48 most, 6 or 8 become a row, handle the liquid that overflows in the experimental implementation process for convenience, around positioning boss, designed diffusing liquid fabrication hole, be used for getting rid of the liquid that bag is overflowed by process or test sample processing procedure, help finishing smoothly each experimental implementation process.
In sum, micropore check grillage of the present invention uses versatile and flexible, simple to operation, is more suitable for simultaneously producing needs greatly, and the sample preparation, checkout procedure or the antigen-antibody bag that can be used for partial-automatic checker are by process.Because the particular design at assembling position between its positioning boss and the reaction cup, promptly internal cavities and outer wall bielliptic(al) structure make the present invention use and are easy to dismantle, and assemble and quite firm.Cooperate with reaction cup, it is little to use its detection data of carrying out medical science or Bioexperiment influenced by external condition, and it is safer that experiment is detected, simultaneously, use flexible, convenient, save and make the present invention have very strong practicality, be suitable for promoting.
Description of drawings
The whole schematic perspective view of Figure 1A micropore check of the present invention grillage
The whole schematic top plan view of Figure 1B micropore check of the present invention grillage
Fig. 1 C reaction cup front elevation
Fig. 2 A positioning boss structural representation (facing and vertical view)
Fig. 2 B positioning boss longitudinal section and cross sectional representation
Fig. 2 C positioning boss and reaction cup package assembly synoptic diagram
Each label lists as follows among the figure:
1-grillage housing, 2-baseplane, 3-positioning boss, 4-boss inwall, 5-outer wall of boss, 6-boss through hole, the 7-liquid fabrication hole that looses, 8-reaction cup, 9-bottom cavity, 10-jacking mechanism, the high seamed edge in 11-both sides, the short seamed edge in 12-both sides
Embodiment
Shown in Figure 1A, Figure 1B, Fig. 2 C, micropore check grillage provided by the invention adopts the one-time formed preparation method of polystyrene material mold pressing to make, and it comprises cuboid grillage housing 1 and positioning boss 3.Design feature is: the high seamed edge 11 in both sides has the 1-8 figure denote respectively before and after the grillage, and the short seamed edge 12 in the left and right sides is respectively A, B, and C, D, E, F letter and the LOGO of company indicate; There is the through hole 6 on positioning boss 3 and the grillage baseplane 2 to connect inside, and direction stretches in plate, form the cavity structure of up/down perforation, boss inwall 4 is cylindrical cylinder, outer wall of boss 5 is a bielliptic(al) shape cylinder, leave the liquid fabrication hole 7 that looses on every side, during use, reaction cup 8 on the single or micropore lath is fastened on corresponding positioning boss 3 positions on the micropore grillage baseplane 2, when carrying out antigen-antibody bag quilt or respective sample detection, reagent cup 8 can assemble fast with micropore check grillage, directly is placed on the special instrument and detects, and will reagent cup 8 not take out; In addition, when carrying out single sample or small amount of sample when detecting, can select the micropore lath of respective numbers or reaction cup 8 to be assembled on the micropore inspection panel according to the test sample number and detect, use efficient simplification.
As Fig. 2 A, 2B, micropore check grillage of the present invention shown in the 2C, for fixation reaction cup 8 better, reaction cup 8 stably is fastened on the micropore check grillage, in 2 through holes, 6 positions, baseplane of grillage housing 1 or the assembly of fixation reaction cup 8 can be set on every side, the present invention has preferably designed positioning boss 3 above through hole 6, these outer wall of boss 4 can be cylindrical, prismatic, bielliptic(al) cylindricality etc., its cardinal principle is that the interference fit that is about 0.15-0.20mm by size design connects, just in time adaptive with reagent reacting cup 8 bottom cavity 9, positioning boss 3 insertion reaction cups 8 bottom cavity 9 during use, and chucking reaction cup 8.Further in order to fix reaction cup 8 more securely, the preferred bielliptic(al) cylindricality outer wall 5 of positioning boss 3, behind this structure and reaction cup 8 bottom cavity 9 fits suitable gap is arranged, like this, under inside and outside tension force effect, can suitably adjust the processing dimension error between positioning boss 3 and the reaction cup 8 by plasticity deformation takes place, thereby make fit more fastening, more stable firmly reaction cup 8.For reaction cup is placed steadily, grillage baseplane 2 provides a locating surface, makes should be close to fully with the grillage bottom cup wall of cup lower end after the interference fit, is positioned on each reaction cup of correct position at grade, and is parallel with the grillage baseplane.The reaction cup that fixes is 8 steady, fastening, be convenient to flexible operating, can carry out respective handling or carry out the detection task, and discarded behind reaction cup 8 complete corresponding operatings, only need add new reaction cup 8 just can carry out new detection task.
Shown in Fig. 2 C, when reaction cup 8 after executing corresponding operating on the microwell plate, 8 of this reaction cup must be discarded, can be by manually reaction cup 8 being taken off from positioning boss 3, the present invention has designed a cavity that connects with grillage baseplane through hole 6 on positioning boss 3, can deliver to reaction cup 8 jack-up from positioning boss 3 again the discarded bucket by through hole 6 with jacking mechanism 10, like this can be safer.
Positioning boss 3 on the micropore check grillage of the present invention mostly is 48 most, 6 or 8 become a row, handle the liquid that overflows in the experimental implementation process for convenience, the present invention has designed diffusing liquid fabrication hole 7 around positioning boss 3, be used for getting rid of the liquid that bag is overflowed by process or test sample processing procedure, help finishing smoothly each experimental implementation process.
The bielliptic(al) positioning boss on the micropore check grillage provided by the invention and the unique design of location base plane structure, make its advantage, be used for multiple test experience operation such as antigen, antibody sandwich process and clinical medical inspection with dismounting flexibly, good stability.
Claims (10)
1. a micropore check grillage comprises grillage housing and 48 positioning boss that reaction cup can be installed, and it is characterized in that: the grillage housing is prolate side's shape, and grillage has bielliptic(al) cylindricality positioning boss inside, and the grillage bottom surface is a plane.
2. according to the described micropore check of claim 1 grillage, it is characterized in that: through hole connects on described positioning boss and the grillage baseplane, and direction stretches in plate.
3. according to the described micropore check of claim 2 grillage, it is characterized in that: described positioning boss inwall is the right cylinder cylinder, and external wall cross-section is orthogonal bielliptic(al), and outer wall surface is the bielliptic(al) cylindrical structure.
4. according to the described micropore check of claim 3 grillage, it is characterized in that: described positioning boss is a hollow structure.
5. according to the described micropore check of claim 1 grillage, it is characterized in that: leave the liquid fabrication hole that looses around the described positioning boss, and run through the grillage baseplane.
6. according to the described micropore check of claim 1-5 grillage, it is characterized in that: positioning boss bielliptic(al) shape structure is just in time suitable with the reaction cup bottom cavity, and the interference fit that is about 0.15-0.20mm by size connects, and is used to tighten reaction cup.
7. according to the described micropore check of claim 1-6 grillage, it is characterized in that: the grillage baseplane provides a locating surface, make should be close to fully with the grillage bottom cup wall of cup lower end after the interference fit, at grade, parallel on each reaction cup of having good positioning with the grillage baseplane.
8. according to the described micropore check of claim 1 grillage, it is characterized in that: the high seamed edge in both sides has the 1-8 figure denote respectively before and after the grillage, and the short seamed edge in the left and right sides is respectively A, B, and C, D, E, F letter and the LOGO of company indicate.
9. according to the described micropore check of claim 1-8 grillage, it is characterized in that: the preparation method of described micropore check grillage, adopt the one-time formed mode of mold pressing to be prepared from.
10. according to the described micropore check of claim 1-9 grillage, it is characterized in that: it is polystyrene that described micropore inspection panel is put up section bar matter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101700842A CN102004144A (en) | 2009-09-03 | 2009-09-03 | Micropore check board frame |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2009101700842A CN102004144A (en) | 2009-09-03 | 2009-09-03 | Micropore check board frame |
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| Publication Number | Publication Date |
|---|---|
| CN102004144A true CN102004144A (en) | 2011-04-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2009101700842A Pending CN102004144A (en) | 2009-09-03 | 2009-09-03 | Micropore check board frame |
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| CN (1) | CN102004144A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104162459A (en) * | 2014-07-21 | 2014-11-26 | 凯和生物科技(上海)有限公司 | Stacked reaction cup |
-
2009
- 2009-09-03 CN CN2009101700842A patent/CN102004144A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104162459A (en) * | 2014-07-21 | 2014-11-26 | 凯和生物科技(上海)有限公司 | Stacked reaction cup |
| CN104162459B (en) * | 2014-07-21 | 2016-04-20 | 凯和生物科技(上海)有限公司 | A kind of superposing type reaction cup |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110406 |