CN102000268B - Oral traditional Chinese medical preparation for treating rheumatism and rheumatoid diseases - Google Patents

Oral traditional Chinese medical preparation for treating rheumatism and rheumatoid diseases Download PDF

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CN102000268B
CN102000268B CN2009100727814A CN200910072781A CN102000268B CN 102000268 B CN102000268 B CN 102000268B CN 2009100727814 A CN2009100727814 A CN 2009100727814A CN 200910072781 A CN200910072781 A CN 200910072781A CN 102000268 B CN102000268 B CN 102000268B
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radix
herba
rheumatoid
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CN102000268A (en
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才廷进
夏秀芬
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Heilongjiang Yichenbeiyao Pharmaceutical Co., Ltd.
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HEILONGJIANG YICHENBEIYAO PHARMACEUTICAL CO Ltd
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Abstract

The invention relates to an oral traditional Chinese medical preparation for treating rheumatism and rheumatoid diseases. Limb pain or numb caused by wind, coldness and wetness is called as a Bi syndrome in traditional Chinese medical science and mainly caused by the sudden attacks of the wind, the coldness and the wetness which flow through meridians and joints and block qi and blood, and the rheumatoid disease is a synovitis-based arthropathy caused by an autoimmune response because of infectious diseases. The oral traditional Chinese medical preparation for treating rheumatism and rheumatoid diseases is prepared from the following components in parts by weight: 15-25 parts of astragalus, 5-15 parts of ephedra, 5-15 parts of papaya, 5-15 parts of loranthaceae, 5-15 parts of lycopodium calvatum, 5-15 parts of henry magnoliavine stems, 5-15 parts of homalomena occulta, 5-15 parts of couchgrass root, 5-15 parts of angelica, 5-15 parts of achyranthes, 1-5 parts of dried immature fruit of citron orange, 5-15 parts of orientavine, 15-25 parts of clematis chinensis, 5-15 parts of cassia twig, 5-15 parts of garden balsam stem and 1-10 parts of dipsacus asperoides. The invention is applied to treat rheumatism and rheumatoid diseases.

Description

A kind of oral preparation of Chinese traditional medicinal of treating rheumatic and rheumatoid diseases
Technical field:
The present invention relates to a kind of Chinese herbal medicine combination formula, particularly a kind of oral preparation of Chinese traditional medicinal of treating rheumatic and rheumatoid diseases.
Background technology:
Rheumatism, rheumatoid arthritis are a kind of comparatively general chronic and obstinate commonly encountered diseases, frequently-occurring diseases.Clinical manifestation is that arthralgia or the. fugitive pain, numb limbs and tense tendons, joint deformity, action are obstructed, have in addition permanent disbility, the serious people health that endangering.This type of patient is in rising trend at present.Mainly be synovial membrane inflammation in early days, synovial membrane hyperemia, swelling, have fibrin to ooze out, form hydrarthrosis, typical inflammatory cell infiltration is arranged in the synovial membrane, involve articular cartilage and osseous tissue then, finally cause ankylosis.That ill joint shows as is red, swollen, hot, pain and moving obstacle, and joint deformity is more and more obvious, and patient's rheumatoid factor is often positive, and the X ray examination has significantly unusual performance.
The traditional Chinese medical science claims that by wind, cold, wet limbs pain or the numbness that causes be arthromyodynia, mainly is that multiple abscess meridians, joint hinder due to the QI-blood circulation by wind, cold, wet taking advantage of a weak point.Wherein rheumatoid be by the autoimmune response that some infectious disease cause cause with the synovitis be the basis arthropathy.
Secondly doctor trained in Western medicine mainly is an oral drug therapy to treatment of rheumatoid arthritis, and salicylic acid formulation example such as aspirin are drug of first choice, is indometacin, Phenylbutazone and prednisone etc., to end-stage patients' treatment that can undergo surgery.
In sum, still not having specific short aspect treatment rheumatism, the rheumatoid disease, so invent the fervent expectation that this disease of treatment by Chinese herbs of a kind of treating both the principal and secondary aspects of a disease has become extensive patients.
Summary of the invention:
The purpose of this invention is to provide a kind of is main with dredge the meridian passage, blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, strengthen the blood stasis expelling pain relieving, broken become silted up stimulate the menstrual flow, anti inflammatory blood quickening, expelling wind and removing dampness, relieving the exterior syndrome by diaphoresis, temperature three-way meridian be the optimal a kind of oral preparation of Chinese traditional medicinal of treating rheumatic and rheumatoid diseases of this type of disease.
Above-mentioned purpose realizes through following technical scheme:
The oral preparation of Chinese traditional medicinal of treatment rheumatic and rheumatoid diseases; Its composition comprises: the Radix Astragali, Herba Ephedrae, Fructus Chaenomelis, Herba Taxilli, Herba Lycopodii, Caulis seu Radix Schisandrae Henryi, Rhizoma Homalomenae, Rhizoma Imperatae, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Fructus Aurantii Immaturus, Caulis Sinomenii, Radix Clematidis, Ramulus Cinnamomi, Herba speranskiae tuberculatae, Radix Dipsaci, described astragalus weight umber are that 15-25 part, Herba Ephedrae parts by weight are that 5-15 part, Fructus Chaenomelis parts by weight are that 5-15 part, Herba Taxilli parts by weight are that 5-15 part, Herba Lycopodii parts by weight are that 5-15 part, Caulis seu Radix Schisandrae Henryi parts by weight are that 5-15 part, Rhizoma Homalomenae parts by weight are that 5-15 part, Rhizoma Imperatae parts by weight are that 5-15 part, Radix Angelicae Sinensis parts by weight are that 5-15 part, Radix Achyranthis Bidentatae parts by weight are that 1-5 part, Fructus Aurantii Immaturus parts by weight are that 1-5 part, Caulis Sinomenii parts by weight are that 5-15 part, Radix Clematidis parts by weight are that 15-25 part, Ramulus Cinnamomi parts by weight are that 5-15 part, Herba speranskiae tuberculatae parts by weight are that 5-15 part, Radix Dipsaci parts by weight are 1-10 part.
Described a kind of oral preparation of Chinese traditional medicinal of treating rheumatic and rheumatoid diseases: described oral formulations adopts conventional Chinese medicine preparation technology, various components is processed into the weighing of 80-120 order fine powder is used as medicine, and can be made into powder, pill, tablet or capsule.
Beneficial effect of the present invention:
1. the present invention provides a kind of Chinese medicine composition of treating rheumatic and rheumatoid diseases---" eliminating rheumatalgia capsule " oral formulations, on the basis of secret prescription handed down in the family from generation to generation, through the clinical use of decades; Through the patient is followed the tracks of return visit, this medicine has fabulous curative effect, and is prone to absorb; Instant effect is difficult for recurrence.
2. the present invention " eliminating rheumatalgia capsule " can take separately, also can cooperate another patent " a kind of Chinese medicine external use plaster of treating rheumatic and rheumatoid " effect of I invent multi better.
3. pharmaceutical preparation technology of the present invention is simple, cost is low, will remove painful for extensive patients.
The rheumatic arthritis diagnostic criteria:
1. be main with the big arthralgia of extremity, bend and stretch symptoms such as inconvenience, heating with miserable numbness, joint.
2. the painful history of pharynx is arranged before the disease or paddle and drench with rain and occupy the wetland history for a long time.
3. the part patient can have low grade fever, extremity erythema iris or erythema nodosum, heart often to get involved.
4. erythrocyte sedimentation rate value (ESR)>20mm/h, anti-hemolysis property streptostacin 0>500u.
The rheumatoid arthritis diagnostic criteria:
1. at least 1 hour (this symptom duration is more than 6 weeks) of deadlock morning.
2.3 individual or 3 above swollen joints (this symptom duration is more than 6 weeks).
3. carpometacarpal joints or PIP swell (this symptom duration is more than 6 weeks).
4. limb inferior thyroid tubercle.
5. hands X sheet changes (have at least osteoporosis and joint space narrow).
6. symmetry swollen joint (this symptom duration is more than 6 weeks).
7. rheumatoid factor (RF) positive.
All patients possess 4 above persons of above standard, just can be diagnosed as rheumatoid arthritis.
Curative effect judging standard:
1. cure: diagnostic criteria recovers below the normal erythrocyte sedimentation rate value 15mm/h.Symptom all disappears, and it is normal that functional activity recovers.
2. produce effects: clinical symptoms disappears basically, and it is normal that sign inspection index still fails to recover.
3. effective: clinical fundamental symptoms alleviates, and main function of joint has clear improvement.
4. invalid: the treatment front and back are no change as a result.
But its therapeutic effect reference table 1 all ages and classes clinical data statistics.
Table 1 all ages and classes clinical data statistics
Figure G2009100727814D00031
5. visible by above clinical data, but the advantage of medicine of the present invention is treating both the principal and secondary aspects of a disease, can alleviate and cure rheumatism, rheumatoid disease faster.And can make erythrocyte sedimentation rate value, rheumatoid factor and anti-hemolysis property streptostacin 0 etc. recover normal, effectively improve patient's self immunity.And have alleviation and healing effect, be difficult for recurrence.Taking convenience, toxic and side effects are little.
The specific embodiment:
Embodiment 1:
A kind of oral preparation of Chinese traditional medicinal of treating rheumatic and rheumatoid diseases; Its composition comprises: the Radix Astragali, Herba Ephedrae, Fructus Chaenomelis, Herba Taxilli, Herba Lycopodii, Caulis seu Radix Schisandrae Henryi, Rhizoma Homalomenae, Rhizoma Imperatae, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Fructus Aurantii Immaturus, Caulis Sinomenii, Radix Clematidis, Ramulus Cinnamomi, Herba speranskiae tuberculatae, Radix Dipsaci, described astragalus weight umber are that 15-25 part, Herba Ephedrae parts by weight are that 5-15 part, Fructus Chaenomelis parts by weight are that 5-15 part, Herba Taxilli parts by weight are that 5-15 part, Herba Lycopodii parts by weight are that 5-15 part, Caulis seu Radix Schisandrae Henryi parts by weight are that 5-15 part, Rhizoma Homalomenae parts by weight are that 5-15 part, Rhizoma Imperatae parts by weight are that 5-15 part, Radix Angelicae Sinensis parts by weight are that 5-15 part, Radix Achyranthis Bidentatae parts by weight are that 1-5 part, Fructus Aurantii Immaturus parts by weight are that 1-5 part, Caulis Sinomenii parts by weight are that 5-15 part, Radix Clematidis parts by weight are that 15-25 part, Ramulus Cinnamomi parts by weight are that 5-15 part, Herba speranskiae tuberculatae parts by weight are that 5-15 part, Radix Dipsaci parts by weight are 1-10 part.
Described a kind of oral preparation of Chinese traditional medicinal of treating rheumatic and rheumatoid diseases, described oral formulations adopt conventional Chinese medicine preparation technology, various components are processed into the weighing of 80-120 order fine powder are used as medicine, and can be made into powder, pill, tablet or capsule.
Embodiment 2:
The concrete prescription of the oral preparation of Chinese traditional medicinal of embodiment 1 described treatment rheumatic and rheumatoid diseases is 10 parts of the Radixs Astragali, 10 parts in Herba Ephedrae, 10 parts of Fructus Chaenomeliss, 10 parts of Herba Taxillis, 10 parts of Herba Lycopodiis, 10 parts of Caulis seu Radix Schisandrae Henryi, 10 parts of Rhizoma Homalomenae, 10 parts of Rhizoma Imperataes, 10 parts of Radix Angelicae Sinensis, 3 parts of Radix Achyranthis Bidentataes, 3 parts of Fructus Aurantii Immaturuss, 10 parts of Caulis Sinomeniis, 20 parts of Radix Clematidis, 10 parts of Ramulus Cinnamomi, 10 parts of Herba speranskiae tuberculataes, 5 parts of Radix Dipsaci.Oral formulations adopts conventional Chinese medicine preparation technology, various components is processed into the weighing of 80-120 order fine powder is used as medicine, and can be made into powder, pill, tablet or capsule.Wherein be preferably capsule.
The oral preparation of Chinese traditional medicinal of described treatment rheumatic and rheumatoid diseases, treatment rheumatic arthritis, rheumatoid arthritis diagnostic criteria, curative effect judging standard and model case:
Model case:
Case 1, king XX, woman, 60 years old, the Bin Xi town peasant of Bin County.
On February 4th, 1998 went to a doctor, and private prosecution have the cold-damp pain, over nearly 4 years, and the right lower limb gonalgia; Stiff, joint stuffiness, knee joint is not beaten and is bent when walking, and meets a day cloudy blowing and raining state of an illness and increases the weight of; Soreness of waist fear of cold at ordinary times, and have the decortication of both hands fingers and palms concurrently and itched about 30 years, can not contact detergent, can not eat the chicken and duck flesh of fish; Invalid through seeking medical advice in many ways, knee joint is not red does not itch through looking into, and the light red tongue moderate pulse is diagnosed as the double fungal infection of hand and foot of the cold-dampness type arthromyodynia (gonarthritis) of suffering from a deficiency of the kidney; Obey medicine of the present invention " eliminating rheumatalgia capsule ", obey 5 every day three times at every turn, cooperate external application " eliminating rheumatalgia plaster ".Through following up a case by regular visits to, after three months, the gonalgia begins to alleviate, and walking can be crooked, and palm refers to that decortication is itched to begin to take a turn for the better, obeyed half a year after, last disease is fully recovered like ordinary person.For after treatment, enjoin it to continue again to obey again three months, to consolidate curative effect.Follow up a case by regular visits to through in November, 2003, primary disease is not recurrence again.
Case 2, merchant XX, the man,, 52 years old, the self-employed entrepreneurs.
On June 14th, 1998 went to a doctor, private prosecution, and cause received rheumatism in spite of the rain and caused whole body arthralgia in 10 years, gradually to little joint deformity, stiff pain is invalid through seeking medical advice in many ways.Look into plain body and become thin, with a haggard face, gloomy simple and unadorned, refer to the toe joint enlargement; Elbow, shoulder knee joint, hip joint be pain all, stomachache, and diet is not good enough, the xerostomia hyperhidrosis; Asthenia is unable, is diagnosed as hepatic and renal YIN deficiency, wind and cold heat of wetting, the cloudy one-tenth of expectorant blood stasis numbness; Obey medicine of the present invention " eliminating rheumatalgia capsule ", obey 5 every day three times at every turn, cooperate external application " eliminating rheumatalgia plaster ".Follow up a case by regular visits to after three months, the joint of enlargement fades, and big arthralgia subtracts greatly, and stomach is not bitterly; After continue drink-service half a year again after, appetite increases to 1 bowl by half bowl, the whole body sweating is received, body weight increases to 52 kilograms by original 48 kilograms; Whole body is strong, and is no longer tired, and the joint of enlargement disappears and fully recovers.
Case 3, Tan XX, woman, the Chinese, 42 years old, Harbin City's the 9th secondary school teachers.
On March 19th, 2003 went to a doctor, and private prosecution in the memory, just suffers from rheumatism during from the youth, and the back state of an illness of bearing child certainly increases the weight of, every value climate change, and just ache in the whole body joint.In recent years and sense lumbago, wrist and ankle painful very, dizziness, asthenia, insomnia, hyperhidrosis, hands and feet coolness, aversion to wind.Look into shallow complexion, the eyelid color is white, and the light red tongue color is blue or green, a little less than the deep-thready pulse, is diagnosed as the numbness of suffering from a deficiency of the kidney, and insufficiency of vital energy and blood is controlled suitable warming and recuperating the kidney-YANG, benefiting vital QI and blood.Obey medicine of the present invention " eliminating rheumatalgia capsule ", obey 5 every day three times at every turn, cooperate external application " eliminating rheumatalgia plaster ".After 2 months, 16 days two May in 2003 examined, and clothes backs appetite increases, and asthenia also goes, and dizziness, insomnia, hyperhidrosis be completely without, aversion to wind only, the trick wrist pain, and hands and feet coolness disease still exists, follow-up clothes medicine of the present invention four months.JIUYUE 22 followed up a case by regular visits to, aversion to wind and cold not, and the trick wrist pain is healed.

Claims (2)

1. treat rheumatism, rheumatoid oral preparation of Chinese traditional medicinal for one kind; Its composition comprises: the Radix Astragali, Herba Ephedrae, Fructus Chaenomelis, Herba Taxilli, Herba Lycopodii, Caulis seu Radix Schisandrae Henryi, Rhizoma Homalomenae, Rhizoma Imperatae, Radix Angelicae Sinensis, Radix Achyranthis Bidentatae, Fructus Aurantii Immaturus, Caulis Sinomenii, Radix Clematidis, Ramulus Cinnamomi, Herba speranskiae tuberculatae, Radix Dipsaci is characterized in that: described astragalus weight umber is that 15-25 parts, described Herba Ephedrae parts by weight are that 5 one 15 parts, described Fructus Chaenomelis parts by weight are that 5 one 15 parts, described Herba Taxilli parts by weight are that 5 one 15 parts, described Herba Lycopodii parts by weight are that 5 one 15 parts, described Caulis seu Radix Schisandrae Henryi parts by weight are that 5 one 15 parts, described Rhizoma Homalomenae parts by weight are that 5 one 15 parts, described Rhizoma Imperatae parts by weight are that 5 one 15 parts, described Radix Angelicae Sinensis parts by weight are that 5 one 15 parts, described Radix Achyranthis Bidentatae parts by weight are that 1-5 part, described Fructus Aurantii Immaturus parts by weight are that 1-5 part, described Caulis Sinomenii parts by weight are that 5 one 15 parts, described Radix Clematidis parts by weight are that 15-25 parts, described Ramulus Cinnamomi parts by weight are that 5 one 15 parts, described Herba speranskiae tuberculatae parts by weight are that 5 one 15 parts, described Radix Dipsaci parts by weight are 1-10 part.
2. according to the described a kind of treatment rheumatism of claim l, rheumatoid oral preparation of Chinese traditional medicinal; It is characterized in that: described oral formulations adopts conventional Chinese medicine preparation technology; Various components are processed into 80-120 order fine powder weighings are used as medicine, can be made into powder, pill, tablet or capsule.
CN2009100727814A 2009-09-02 2009-09-02 Oral traditional Chinese medical preparation for treating rheumatism and rheumatoid diseases Expired - Fee Related CN102000268B (en)

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