CN101991613A - Diarrhea and dysentery arresting medicine and preparation method thereof - Google Patents

Diarrhea and dysentery arresting medicine and preparation method thereof Download PDF

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Publication number
CN101991613A
CN101991613A CN2010105323167A CN201010532316A CN101991613A CN 101991613 A CN101991613 A CN 101991613A CN 2010105323167 A CN2010105323167 A CN 2010105323167A CN 201010532316 A CN201010532316 A CN 201010532316A CN 101991613 A CN101991613 A CN 101991613A
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CN
China
Prior art keywords
medicine
dysentery
antidiarrheal dysentery
berberin
tannate
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Pending
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CN2010105323167A
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Chinese (zh)
Inventor
庞永中
庞雁
朱明�
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Individual
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Individual
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Priority to CN2010105323167A priority Critical patent/CN101991613A/en
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Abstract

The invention discloses a diarrhea and dysentery arresting medicine and a preparation method thereof, relating to a veterinary oral medicine and a preparation method thereof. The diarrhea arresting medicine of the invention comprises dry meat meal, dried yeast and tannic acid. The method comprises the following steps of: (1) baking and crushing fresh meat; (2) mixing medicines and an additive except for cane sugar and uniformly stirring; (3) adding 100ml of water into the cane sugar, and boiling for forming syrup; (4) uniformly spraying the syrup on a mixture obtained in the step (2), and baking at 80 DEG C; and (5) granulating and packaging. The diarrhea and dysentery arresting granules are produced in three batches with the weight of 150kg in total, some of the granules are applied to 183 common domestic cats and 232 persian cats, with the total effective rate of 100% and the cure rate of 99.02%, and others are applied to 403 dogs in total, including 271 Shih Tzus, 7 wolf dogs, 112 hybridized wolf dogs and 13 native domestic dogs, with the total effective rate of 100% and the cure rate of 98.87%.

Description

A kind of antidiarrheal dysentery medicine and preparation method thereof
[technical field]
The present invention relates to a kind of oral medicine for animals and preparation method thereof.
[background technology]
Diarrhoea and dysentery are the common intestinal tract diseases of cat and dog, and the Therapeutic Method of most convenient is to take medicine.Existing many these type of medicines in people's medication are as XIELITING (a kind of by sulfaguanidine, trimethoprim, the mixed tablet that gets of scopolamine).But having a sharp sense of taste of cat or dog generally be unwilling to be eaten and be with the thing of flavour of a drug.
At present, cat or dog got diarrhoea and dysentery, and method commonly used is to catch its treatment of having an injection.But under the situation that does not cause systemic infection, have an injection treatment diarrhoea and dysentery are not good methods.Because diarrhoea might be that cause pathogeny imcrobe infection causes, also may dyspepsia cause.Treatment diarrhoea and the dysentery that pathogenic microorganism is caused of having an injection has certain curative effect, but the diarrhoea that dyspepsia is caused is invalid substantially or produce little effect.In addition, diarrhoea and dysentery generally only infect the intestinal part, concentrate medicine throwing side to intestinal, form local high relatively drug level, and curative effect can be better.The medicine distribution whole body of having an injection need not the also medication of place of medication, often increases side effect.
[summary of the invention]
At the problems referred to above, the invention provides a kind of medicine that can effectively treat diarrhoea or dysentery.
The present invention also provides manufacturing method for above mentioned medicine.
Antidiarrheal dysentery medicine of the present invention, it contains meat powder, dry yeast, tannic acid.
According to different situations, described antidiarrheal dysentery medicine can also contain berberin tannate, gentamycin sulfate, perhaps also can also contain pepsin, edible citric acid.
When being used for the treatment of the diarrhoea that causes because of dyspepsia, described antidiarrheal dysentery medicine contains meat powder 50g among every 1000g, pepsin 75000 units, edible citric acid 50g, tannic acid 5g, dry yeast 50g.
When being used for the treatment of when causing suffering from diarrhoea because of enterobacterial infection, described antidiarrheal dysentery medicine contains meat powder 50g among every 1000g, berberin tannate 1.5g, gentamycin sulfate 250 million international units, tannic acid 5g, dry yeast 20g.
When being used for the treatment of not only bacterial infection but also dyspepsia, described antidiarrheal dysentery medicine preferably contains berberin tannate, gentamycin sulfate, pepsin and edible citric acid.Wherein further preferred, the described antidiarrheal dysentery of every 1000g medicine contains meat powder 50g-150g, berberin tannate 0.5-2.5g, gentamycin sulfate 150-375 million international units, pepsin 25000-125000 unit, edible citric acid 10-100g, dry yeast 20-100g, tannic acid 2-10g.
In order further to improve drug effect, in a preferred embodiment, described antidiarrheal dysentery medicine also contains the 15mg atropine sulfate.In wherein can the described medicine of further preferred every 1000g, contain meat powder 100g, berberin tannate 1.5g, atropine sulfate 15mg, gentamycin sulfate 250 million international units, pepsin 75000 units, edible citric acid 50g, dry yeast 50g, tannic acid 5g.
In another preferred embodiment, described antidiarrheal dysentery medicine also contains additive, and described additive is essence, sucrose, grain dust.In wherein can the described medicine of further preferred every 1000g, contain essence 0.5g, sucrose 30g, remain and be grain dust.
Above-mentioned meat powder is preferably beef dry powder or flesh of fish dry powder.
A kind of method for preparing above-mentioned antidiarrheal dysentery medicine may further comprise the steps:
(1) with fresh meat oven dry, pulverizing;
(2) except that sucrose, medicine and additive are mixed, mix all;
(3) sucrose is added the 100ml water boil and become syrup;
(4) syrup evenly is sprayed on the mixture that step (2) makes 80 ℃ of oven dry;
(5) granulate, packing gets final product
Antidiarrheal dysentery granule of the present invention has been produced 3 batches of 150kg altogether, some of them are applied to 183 of domestic cats, (pet clinic stays to be cured 177 to 232 of persian cat, wherein bacillary dysentery is 166,3 of digestibility diarrhoea, 4 of coli-infection secondary rotavirus, 2 of dysentery bacterium secondary parvovirus, 2 of the not clear causes of disease), total effective rate 100%, cure rate 99.02%.Other are applied to 271 of Xisi, famous beauty in the late Spring and Autumn Period Canis familiaris L.s, 7 of wolf dogs, 112 of wolf dogs of hybridization, 13 of soil species man Canis familiaris L.s, add up to 403, total effective rate 100%, cure rate 98.87%.
[specific embodiment]
Embodiment one cat is used antidiarrheal dysentery granule
1, material and manufacture method
1.1 material
The about 500g of the fresh flesh of fish, takes by weighing 100g after pulverizing at 105 ℃ of oven dry, and other takes by weighing
Berberin tannate 1.5g
Gentamycin sulfate 250 million international units
Pepsin 75000 ius
Edible citric acid 50g
Dry yeast 50g
Atropine sulfate 15mg
Tannic acid 5g
Essence 0.5g
Sucrose 30g
Grain dust adds to 1000g
1.2 method for making
Sucrose is added water 100ml boil into syrup, all the other raw material adjuvants mix, and mix all, and syrup evenly is sprayed on the supplementary material, make the semi-wet granule, 80 ℃ of oven dry, granulate.
2, usage and consumption
Oral, once measure, every 1kg body weight 2g (allowable error ±≤20%) once-a-day, generally only obeys once, and obeyed once in 24 hours again at indivedual serious symptom persons interval.
3, applicable cases
Certain soil species domestic cat, body weight 1.8kg, because of gluttony flesh of fish diarrhoea, untimely treatment, secondary dysentery 4 days, anorexia, this product of throwing something and feeding 4g has eaten, and no longer draws dysentery, next day to search for food normally, and dung was just normal on 3.
Embodiment two dogs are used antidiarrheal dysentery granule
1.1 material
The about 500g of fresh beef, takes by weighing 100g after pulverizing at 105 ℃ of oven dry, and other takes by weighing
Berberin tannate 1.5g
Gentamycin sulfate 250 million international units
Pepsin 75000 units
Citric acid 50g
Dry yeast 50g
Atropine sulfate 15mg
Tannic acid 5g
Essence 0.5g
Sucrose 30g
Grain dust adds to 1000g
1.2 method for making
Sucrose is added water 100ml boil into syrup, all the other raw material adjuvants mix, and mix all, and syrup evenly is sprayed on the supplementary material, make the semi-wet granule, 80 ℃ of oven dry, granulate.
2, usage and consumption
Oral, once measure, every 1kg body weight 2g (allowable error ±≤20%),, once-a-day, generally only to obey once, obeyed once in 24 hours again at indivedual serious symptom persons interval.
3, certain hybridization wolf dog, body weight 25.6kg, coliform diarrhea 2 days, the 50g antidiarrheal of throwing something and feeding dysentery granule, total eclipse is intact, and for drinking-water, antidiarrheal was once crossed dispensing and was cured the same day.

Claims (10)

1. an antidiarrheal dysentery medicine is characterized in that it contains meat powder, dry yeast, tannic acid.
2. antidiarrheal dysentery medicine as claimed in claim 1 is characterized in that it also contains berberin tannate, gentamycin sulfate, and perhaps it also contains pepsin, edible citric acid.
3. antidiarrheal dysentery medicine as claimed in claim 2 is characterized in that containing meat powder 50g in the described medicine of every 1000g, pepsin 75000 units, edible citric acid 50g, tannic acid 5g, dry yeast 50g.
4. antidiarrheal dysentery medicine as claimed in claim 2 is characterized in that meat powder 50g, berberin tannate 1.5g, gentamycin sulfate 250 million international units, tannic acid 5g, dry yeast 20g..
5. antidiarrheal dysentery medicine as claimed in claim 1 is characterized in that it also contains berberin tannate, gentamycin sulfate, pepsin, edible citric acid.
6. antidiarrheal dysentery medicine as claimed in claim 5, it is characterized in that in the described medicine of every 1000g, contain meat powder 50g-150g, berberin tannate 0.5-2.5g, gentamycin sulfate 150-375 million international units, pepsin 25000-125000 unit, edible citric acid 10-100g, dry yeast 20-100g, tannic acid 2-10g.
7. as claim 1 or 2 or 3 or 4 or 5 or 6 described antidiarrheal dysentery medicines, it is characterized in that in the described medicine of every 1000g, contain meat powder 100g, berberin tannate 1.5g, atropine sulfate 15mg, gentamycin sulfate 250 million international units, pepsin 75000 units, edible citric acid 50g, dry yeast 50g, tannic acid 5g.
8. as claim 1 or 2 or 3 or 4 or 6 described atropine sulfate antidiarrheal dysentery medicines, it is characterized in that containing essence 0.5g, sucrose 30g in the described medicine of every 1000g, remain and be grain dust.
9. atropine sulfate antidiarrheal dysentery medicine as claimed in claim 8 is characterized in that described meat powder is beef dry powder or flesh of fish dry powder.
10. one kind prepares as claim 1 or 2 or 3 or the method for 4 or 6 or 8 described antidiarrheal dysentery medicines, it is characterized in that may further comprise the steps:
(1) with fresh meat oven dry, pulverizing;
(2) except that sucrose, medicine and additive are mixed, mix all;
(3) sucrose is added the 100ml water boil and become syrup;
(4) syrup evenly is sprayed on the mixture that step (2) makes 80 ℃ of oven dry;
(5) granulate, packing gets final product.
CN2010105323167A 2010-11-03 2010-11-03 Diarrhea and dysentery arresting medicine and preparation method thereof Pending CN101991613A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103301448A (en) * 2012-03-13 2013-09-18 陶箭 Medicine composition for treating multiple kinds of diarrhea of animals
CN103385957A (en) * 2013-07-10 2013-11-13 海宁市巨洋智能科技开发有限公司 Medicinal preparation for curing calf diarrhea
CN103385928A (en) * 2013-07-10 2013-11-13 吉林大学 Compound medical preparation for curing diarrhea of young livestock and applications thereof
CN103919790A (en) * 2014-05-04 2014-07-16 湖南尔康湘药制药有限公司 Method for preparing sulphaguanidine-trimethoprim effervescent tablet
CN104288436A (en) * 2014-09-30 2015-01-21 天津瑞贝特科技发展有限公司 Veterinary injection with effects of astringing intestine to stop diarrhea and preparation method of veterinary injection
CN107812166A (en) * 2017-09-29 2018-03-20 遵义医学院 A kind of feed addictive for preventing fish acute gastroenteritis and preparation method thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
《中国工作犬业》 20050925 周绪正等 硫酸阿托品在犬病临床上的应用 21 7-10 , 2 *
《养殖技术顾问》 20071005 吴娱等 家养犬应常备的药品 89 1-10 , 2 *
《海峡药学》 20091231 叶国英 鞣酸蛋白酵母散治疗婴幼儿秋季腹泻疗效观察 131 1-10 第21卷, 第8期 2 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103301448A (en) * 2012-03-13 2013-09-18 陶箭 Medicine composition for treating multiple kinds of diarrhea of animals
CN103385957A (en) * 2013-07-10 2013-11-13 海宁市巨洋智能科技开发有限公司 Medicinal preparation for curing calf diarrhea
CN103385928A (en) * 2013-07-10 2013-11-13 吉林大学 Compound medical preparation for curing diarrhea of young livestock and applications thereof
CN103919790A (en) * 2014-05-04 2014-07-16 湖南尔康湘药制药有限公司 Method for preparing sulphaguanidine-trimethoprim effervescent tablet
CN103919790B (en) * 2014-05-04 2016-06-08 湖南尔康湘药制药有限公司 A kind of preparation method of sulfaguanidine-trimethoprim effervescent tablet
CN104288436A (en) * 2014-09-30 2015-01-21 天津瑞贝特科技发展有限公司 Veterinary injection with effects of astringing intestine to stop diarrhea and preparation method of veterinary injection
CN107812166A (en) * 2017-09-29 2018-03-20 遵义医学院 A kind of feed addictive for preventing fish acute gastroenteritis and preparation method thereof

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Application publication date: 20110330