CN101990994A - Anti-heat stress feed additive for improving reproductive function of male rabbits - Google Patents
Anti-heat stress feed additive for improving reproductive function of male rabbits Download PDFInfo
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Abstract
The invention discloses an anti-heat stress feed additive for improving reproductive function of male rabbits. The anti-heat stress feed additive is added to a basal diet feed prepared for maintaining the right amount of recommended NRC (National Research Council) (1977) adult rabbits for uniformly mixing. The anti-heat stress feed additive added to a ton of feed comprises the following components by weight: 100 to 800g of lipoic acid, 100 to 600g of vitamin E, 100 to 600g of vitamin C and 0 to 600g of Saccharicterpenin. A result shows that the additive can obviously improve sperm viability and density and reduce abnormal rate (P<0.05), wherein anti-stress test 3 has the advantage of improving sperm viability; anti-stress test 2 has the advantage of improving sperm density; and all of the three additives can obviously improve the content (P<0.05) of testosterone in serum of heat stress bucks and do not have obvious difference (P>0.05) for improving the content of T3 and cortisol.
Description
Technical field
The invention belongs to field of feed additive technology; relate to a kind of nourishing healthy feed addictive, specifically a kind of anti-heat stress feed additive with functions such as improving buck immunity of organisms, protection reproductive system, maintenance sexual desire, the ejaculate volume that increases, raising semen quality.
Background technology
Heat stress (Heat Stress) is meant when being in the high temperature environment, the summation of nonspecific physiological reaction that any requirement that body proposes thermal environment is done.Heat stress is many-sided to the influence of animal, and at first heat stress influences feed intake and the production performance of animal to feed; Secondly, cause endocrine activity disorder; The 3rd, reduce the immunocompetence of animal, and then influence the health status of animal.Heat stress is very big to the influence of the breeding potential of breeding animals, mainly shows, causes dam puberty postponement, hypo-ovaria, and conception rate descends, and survival rate of embryo is low, postpones wean back sexuality; The sexual desire of male animal, production of sperm ability and semen quality etc. all obviously descend.The reduction of the fertility of animal directly affects Developing of Animal Industry.Closely both at home and abroad during the last ten years the anti-heat stress of livestock has been carried out more research, has now taken passages as follows:
1, people such as Song Zhijuan, heat stress is to influence and the nutrition regulation thereof of rabbit.China's feed addictive, 2006,49 (7).This article summary has been introduced the influence of heat stress to seven aspects of rabbit:
(1) heat stress is to the influence of rabbit feed intake
Animal body all has the optimum temperature of self, and just " comfort zone " refers to and needn't too regulate the ambient temperature scope of keeping normal body temperature by physics.The rabbit normal body temperature is 38.3-39.6 ℃, and is small, and metabolism is vigorous, and quantity of heat production is big in the body, but sweat gland is undeveloped, so very To Be Protected from Heat for rabbit.During the broiling summer, when environment temperature rose to a certain degree in the house, the excitement of the maincenter of searching for food of rabbit was suppressed, and kept the energy that needs and reduced, thereby cause feed intake to descend.Be temperature is had a liking for the food maincenter to hypothalamus direct side effect on the one hand; Be that the alimentary canal activity weakens on the other hand, thereby cause the full of alimentary canal food, oppress mechanoceptor and appetite-suppressing.Amici etc. (1995) report, rabbit hangs down 13.6% when feed intake is than 18 ℃ in the time of 33.5 ℃.
(2) heat stress is to the influence of rabbit production performance
The suitable growth temperature of rabbit is 15-25 ℃.In the continuous high temperature phase, but the feeding center of rabbit is caused feed intake to descend.During heat stress, body suppresses exothermal process owing to strengthen heat radiation, and secretion of digestive juice and stomach and intestine function descend, and the metabolism level lowly causes body weight gains to reduce.Trommel etc. (1996) report, rabbit has reduced by 49.8% at 32.2 ℃ body weight gains during than 23 ℃.Papp etc. (1990) report, in the time of pregnant 20-29 days, the average weightless 87g of the rabbit under the high temperature, and the 298g that increases weight of the female rabbit during thermophilic.In hot environment, because feed intake reduces, the metaboilic level of body descends, and the nutriment supply of hair reduces the poor growth that makes hair, and quantity is few, and clip sharply descends.The quality of temperatures involved hair mainly shows as the coarse wool ratio of rabbit at the height in summer, and the fine hair amount is few; The length of the rabbit hair is shorter than winter in summer; Summer the intensity of the rabbit hair low, degree of stretching is big, fine hair thick (Deying ZHANG etc., 1990).
(3) heat stress is to the influence of female rabbit reproductive performance
High temperature has adverse effect to female rabbit reproductive performance, mainly influences conception rate and the litter size of female rabbit.Under the hot conditions, female rabbit estrogen secretion reduces, and it is irregular to oestrus, and influences the functional activity of normal property.Find that according to the study heat stress can cause the egg cell paramophia, break, it can not be fertilized as cytoplasm contraction or hyaline membrane.Temperature is more than 32.2 ℃ the time, and the rabbit conception rate reduces, and blastular, embryo diminish, and embryo's Infant Mortality raises.Under the hot conditions, the feed intake of female rabbit descends, and causes subalimentation, female rabbit is for increasing heat dissipation capacity simultaneously, and a large amount of blood flow are to skin, thus the CBF of minimizing uterus and umbilical cord, cause the fetus blood supply insufficiency, influence normal fetal development, cause the increase of stiff young rabbit and stillborn foetus number.Huang Lianghu etc. (1995) report, the conception rate of the female rabbit of high temperature season reduces by 91%, and the nest litter size reduces 30%, when environment temperature rises to 30 ℃, the dead 25-45% of embryonated egg.Report in Tan Qizhao etc. (1990) translation that pregnant rabbit is responsive especially to the heat stress of sudden change, if enter 35 ℃ of hot environments suddenly, can cause that hydrostomia, nervous symptoms appear in female rabbit, even miscarriage.Long term high temperature environment (30 ℃) heavily descends the body weight of female rabbit, nest son, and the nest litter size reduces.Temperature raises in the latter half of gestation 10 days, and the lactation amount that makes female rabbit reduces by 72.3% during than thermophilic (20 ℃).
(4) heat stress is to the influence of buck
High temperature can suppress hypothalamus synthesizing with secretion of gonadotropin-releasing hormone (GRH) had a negative impact to the testis function, and the rabbit semen quality is significantly reduced.Yan Zhongshen etc. (1985) discover that when temperature was elevated to 30 ℃, the semen volume of buck, sperm motility and ejaculate volume obviously reduced.Wang Zhi waits (1985) to discover clearly, and rabbit is in 31.5-34.5 ℃ of environment, and semen volume, sperm motility and density become negative correlation with environment temperature, and rate of teratosperm significantly raises.And the generating process of buck sperm interrupts, and convoluted seminiferous tubule hollow only has the first spermatocyte of minority, and all the other androgones at different levels all disappear.Du Yuchuan etc. (1987) report dwindles 25% relatively through 10 days buck testis of 35 ℃ of high-temperature process.
(5) heat stress is to the rabbit Immune Effects
Heat stress stimulates the rabbit body, and body's immunity is suppressed, and this immunosupress is by the regulation and control of brain to immunologic function, and cortex hormone of aadrenaline and orthosympathetic immune modification are used for realizing.When brain is subjected to stress stimulation and even destruction, can cause immunity of organism organ, tissue and cell function to suppress.Lymphokine is synthetic in brain, some hormones in the brain also participate in the adjusting of immunologic function, this body fluid that to be brain transmit information to immune organ by way of, with the pituitary is the center, through hypophysis one adrenal gland by way of regulating, stomodaeal nervous system also by its effect to the adrenergic receptor of immuning tissue's organs such as spleen, lymph node, thymus gland and marrow, directly suppresses body's immunological function.
(6) heat stress is to the influence of inorganic ions in the rabbit anteserum and alkali storage
Being short of breath that heat stress caused can cause CO in the blood
2And H
+Concentration descends and causes acid base imbalance, so-called respiratory alkalosis.Odan (1982) studies show that, respiratory alkalosis can take place in 30 minutes behind heat stress.During heat stress, the rabbit organism metabolism is movable to be strengthened, and heat production increases, and respiratory rate is accelerated, and thermopolypnea takes place, and makes CO
2Discharge rate increases, CO in the blood
2Reserves descend, H
+And HCO
3 -Degree reduces, thereby causes blood to be respiratory alkalosis.Fan Shijun etc. (1996) report, in hot phase and hot phase, serum calcium, potassium, sodium and alkali storage all significantly reduce.Dridi (1993) has also observed the influence of heat stress environment to calcium, phosphorus, potassium, sodium, level of chlorine in the plasma in rabbit, and the result shows, outside the dephosphorization, influenced by heat stress in sodium, potassium, the chlorine whole test in the blood plasma and significantly decline.
(7) heat stress is to the influence of rabbit blood biochemical indicator
EI-Masry etc. (1994) studies show that, descend because thyroid gland is movable, influence the synthetic of protein, and blood total protein, albumin level all obviously descend when making heat stress.Cretinephosphokinase in the serum (CPK) concentration rises, the increased activity of transaminase, and other enzymes such as glutamic-pyruvic transaminase (GPT) and lactic dehydrogenase (CDH) are downward trend.Marai etc. (1999) report, rabbit is under hot environment, and the ratio of blood total protein, albumin, globulin and albumin and albumen all is starkly lower than winter.Zhang Defu etc. (1992) report, rabbit are in the time of 31 ℃, and blood sugar concentration and serum lipid concentrations descend 40% and 33.3% than 20 ℃ respectively.
2, Chinese patent CN 101229152A, application number 200810056588.7, a kind of method that promotes male animal sexual organ development and sperm development.This inventive method is from the male animal vitamin E of feeding childhood.Select suitable dosage according to different livestocks.Usually from the male animal wean vitamin E of can feeding,, can suitably increase dosage when feeding, can stop to feed during to the male animal sexal maturity along with the growth of male animal.Vitamin E powder can be added to when feeding in the fine fodder of children's male animal daily ration in age, fully mix thoroughly, divide and sooner or later feed.For public lamb, the scale of feeding of vitamin E with every day every 80-880IU be advisable, be preferably every every day 320IU.Test shows that male animal begins the vitamin E of feeding from the children age, can increase the weight of attached guilt, and the density of convoluted seminiferous tubule increases attached guilt diameter, androgone quantity, utilizes male animal ahead of time, improves the fertility of sire and utilizes the time limit.
3, Chinese patent CN 101313731A, application number 200810116768.X, a kind of anti-stress feed addictive.The technical scheme of this invention is: its constituent and percentage by weight are: astragalus polyose 15-30%, baicalin 15-30%, peppermint oil wrappage 10-20%, Honegsukle flower P.E 10-20%, vitamin C 0.5-5%, vitamin E 0.5-5%, chromium picolinate 0.001-0.02%, zinc oxide 0.05-0.3%, arginine 0.1-1%, tryptophan 1-5%, glutaminase 1-5%, sodium sulphate 1-5%, calcium iodate 1-3%, sodium selenite 1-3%, potassium dihydrogen phosphate 1-3%, surplus is an acceptable accessories.This prescription adopts the comprehensive compatibility combination of Chinese herbal medicine, amino acid, minerals and vitamins, under anti-stressed condition, can comprehensively promote the dynamic variation of the metabolism of body internal hormone, immunologic function, nutrition physiology and nutritional need, thereby improving the anti-stress effect of animal body, is the wide spectrum poultry and livestock feed additive.
4, Chinese patent CN 101301402A, application number 200810140469.X, the nutrition health care replenisher of reinforcing reproduction performance of boar.The technical scheme that this invention is taked is: total amount is that raw material by weight components constitutes: saccharicter-penin: 1-2 part in 20 parts, nano zine oxide: 1-3 part, chromium picolinate: 0.006-0.01 part, arginine 5-7 part, beta carotene: 0.2-0.3 part, vitamin E: 0.1-0.2 part, vitamin A: 0.1-0.2 part, vitamin C: 0.3-0.6 part, cobalamin: 0.00003-0.00005 part, folic acid 0.004-0.006 part, biotin: 0.0003-0.0006 part, l-cn 0.3-1 part, surplus is a glucose.This prescription to the volume of semen and the semen quality that improve herd boar, safeguard that herd boar health has good action, and have the boar of raising immunity of organisms, bactericidal antiphlogistic function simultaneously, it is powerful that the protection reproductive system is avoided infringement etc.But the material composition of interpolation is more, and cost is higher.
From prior art as can be known: the spermatogenesis of buck is subjected to the control of hypothalamic pituitary gonadal axis, and must can become mature sperm through hatching just of epididymis, suitable temperature is absolutely necessary concerning spermatogenesis, but the testis of buck is very responsive to heat, and temperature raises can cause injury of testis several times.The summer high temperature high humidity directly can cause buck body temperature to raise, and causes that the gentle testis temperature of scrotum skin raises, and causes degeneration of testis, and the maturation of sperm and storage are affected.Elevated temperature heat stress make sperm motility and density reduce, and rate of teratosperm increases.Testosterone is the sex hormone by interstitial glands secretion, to the generation of sperm and have important function.Under the heat stress state, the regulation and control of hypothalamic pituitary gonadal axis are suppressed, and corticotropin-releasing hormone (CRH) secretion increases.Along with the secretion that can directly suppress hypothalamus luteinizing hormone releasing hormone (LHRH) that increases of CRH, cause the luteotropin secretion to reduce, cause that the secretion of testosterone reduces.Thyroid hormone almost acts on all organs of body and tissue, and is all influential to each side such as growth, growth, metabolism and tissue differentiation.Under the heat stress state, heat production is more in the buck body, cause synthetic minimizing of anterior pituitary thyroid-stimulating hormone (TSH) of hypophysis secretion, finally cause the secretion of thyroxine (T4) and triiodo thryonine (T3) to descend, and then cause the variation of a series of Physiology and biochemistry of body.Under the heat stress condition, high temperature stimulates hypothalamus secretion corticotropin-releasing hormone (CRH), CRH causes that hypophysis discharges corticotropin (ACTH) and increases, and ACTH promotes adrenal cortex axle secretion cortisol, so causes cortisol levels to raise under the acute heat stressed condition.If but stimulus intensity is excessive or action time is long, body will lose handling ability gradually, show depleted phenomenon, pathological state appears, therefore cause the imbalance of hypothalamus one hypophysis one adrenal cortex axle, thereby cortisol secretion is reduced, the phenomenon that common slow fever stress cause cortisol levels to descend in the production that Here it is.
Summary of the invention
The object of the invention is to provide a kind of anti-heat stress feed additive that improves buck immunity of organisms, protection reproductive system, maintenance sexual desire, increases functions such as ejaculate volume and raising semen quality that has.
The present invention is achieved in that
Improve the anti-heat stress feed additive of buck reproductive function, keeping requirement the adult rabbit of recommendation NRC (1977) prepares in the basic diet feed, add the anti-heat stress additive, mix, the weight tons feed adds the anti-heat stress additive component and weight is: lipoic acid 100-800g, vitamin E are that 100-600g, vitamin C are that 100-600g and saccharicter-penin are 0-600g.
Above-described interpolation anti-heat stress additive component III and weight are that lipoic acid is that 600g, vitamin E are that 300g and vitamin C are 300g.
The method for breeding of buck: raise buck at summer high-temperature, need disinfections such as surrounding enviroment, rabbit house, raising instruments, buck is raised at same indoor single cage, feed by the special messenger, sooner or later respectively feed the feed 1 time that adds the anti-heat stress additive every day, freely drink water, replenish sufficient green grass every day.
In interpolation anti-heat stress additive each component raw material of the present invention:
Lipoic acid: lipoic acid is a kind of free radical, the similar vitaminic material that can eliminate accelerated ageing and cause a disease, lipoic acid is a kind of mitochondrial ferment that is present in, lipoic acid enters cell in vivo after intestinal absorption, have fat-soluble and water miscible characteristic concurrently, therefore can go everywhere without any hindrance here at whole body, arriving any one cell position, provide buck comprehensive usefulness, is unique fat-soluble and water miscible universal antioxidant that has concurrently.
Saccharicter-penin: saccharicter-penin is a plant extracts, can obviously improve the immunologic function and the anti-stress effect of buck body nerve and internal system, promotes the secretion of cortex hormone of aadrenaline, improves the content of immunoglobulin G (1gG); Eliminate the harmful free radical of body, improve body tissue cell oxidation resistance; Promotion protein synthesizes the physiological function with digestive enzyme activity; Salmonella, Escherichia coli, Eimeria tenella and method capsulitis all there is good inhibition effect; Can improve the general level of the health and the production performance of animal by improving whole immunity and the internal system of animal, can improve buck ejaculate volume and semen quality.
Vitamin E: vitamin E is as antioxidant in the buck cell, the lipid peroxidation that the energy Green Tea Extract causes, safeguard the function of cell membrane system, minimizing stress the time muscle cell creatine kinase release, thereby prevent stream in the too much calcium and cause interference normal cellular metabolism.Simultaneously, cortex hormone of aadrenaline discharged the immunosupress that causes when vitamin E also can be alleviated buck owing to high temperature, can promote the synthetic of immunoglobulin (Ig), thereby improved the resistance against diseases of body.Vitamin E can also reduce the content of buck serum cortisol, thereby reduces the bad reaction of body to heat stress.The blood testosterone of buck, sperm concentration, seminal fluid transaminase activity obviously rise, and improve the reproductive capacity of breeding male rabbit.
Vitamin C: play an important role in the various redox reactions in living cells, participate in the synthetic of sterol in the adrenal cortex, help to alleviate stress, and eliminate the adverse effect of high temperature to semen quality, reduce the cohesive force that is skillful in.After buck increased hello vitamin C, sperm quality increased.During heat stress, ascorbic synthesis capability is reduced, and loss increase, and improves buck significantly for ascorbic demand.
The beneficial effect that the present invention can reach is:
1, anti-heat stress additive of the present invention has the buck of raising immunity of organisms, bactericidal antiphlogistic function; the protection reproductive system is avoided infringement, also can be used for the auxiliary therapy and the prevention of diseases such as guilt nine inflammation, sexual accessory gland inflammation, urodaeum inflammation, blood essence, seminal fluid dirt, sperm cohesion.
2, anti-heat stress additive of the present invention can be regulated endocrine, has production of sperm, improves the buck sexual desire, improves the semen quality function, and it is high that the buck after speech is fed produces smart amount, the sperm concentration height, energetic, abnormal rate is low.
3, the bright anti-heat stress additive of this law can resist various stress.Use in summer, can avoid ejaculate volume to reduce and the bad degree of semen quality effectively.
4, anti-heat stress additive of the present invention has health care, replaces antibiotic, avoids causing serious adverse consequences owing to medicament residue and the pathogenic microorganism resistance to the action of a drug strengthen gradually.
5, anti-heat stress additive of the present invention is through feeding contrast test, proves safe and reliablely, and effect is remarkable.
The specific embodiment
Below come based on embodiment that the present invention is further illustrated, but the present invention is not constituted any restriction.
Embodiment
Select for use Guangxi University to herd that the body condition that provides of examination station is good, body weight is suitable, 24 of the New Zealand buck at 7 monthly ages, be divided into 4 groups, every group of 6 repetitions, the test buck is supported in 31 ± 2 ℃ heat stress environment and raises, and the basal diet group is a control group, other 3 groups is test group, be called 1 group of test at the basis of basal diet adding interpolation vitamin E and vitamin C respectively, add vitamin E and saccharicter-penin and be called 2 groups of tests, interpolation vitamin E, vitamin C and lipoic acid are called tests 3 groups.
The basis diet is with reference to recommending the adult rabbit of NRC (1977) to keep the requirement preparation, and Screening Experiment of Diet and trophic level see Table 1.Testing 1 group of weight tons feed interpolation anti-heat stress additive component and weight is that vitamin E is that 600g and vitamin C are 600g; Testing 2 groups of weight tons feeds interpolation anti-heat stress additive component and weight is that vitamin E is that 300g and saccharicter-penin are 500g; Testing 3 groups of weight tons feeds interpolation anti-heat stress additive component and weight is that vitamin E is that 300g, vitamin C are that 300g and lipoic acid are 600g.
Table 1 Screening Experiment of Diet and trophic level
Method for breeding is: before experiment to disinfections such as surrounding enviroment, rabbit house, raising instruments.After all prerun, just enter and try the phase.Buck is raised at same indoor single cage, is fed by the special messenger, and respectively feed 1 time every day sooner or later, freely drinks water, and replenishes sufficient green grass every day.Raise after two months, carry out artificial semen collection.Adopt once essence in per three days, adopt essence altogether 5 times.
The raising result is: different additive sees Table 2 to the situation that influences of volume of semen, sperm motility, density, abnormal rate.
Table 2 different additive is to the influence of volume of semen, sperm motility, density, abnormal rate
Annotate: in the lowercase shoulder mark of each test data of same column, lowercase difference person, expression significant difference (P＜0.05); The identical person of lowercase, expression difference is remarkable (P＞0.05) not.
Compare with control group, three processed group to elevated temperature heat stress rabbit the impact effect not significantly (P＞0.05) of volume of semen.
Aspect sperm motility, the sperm concentration of control group is minimum; Test 3 groups suitable with 2 groups of tests, and significantly be better than other two groups (P＜0.05); Test 1 group of sperm concentration and also be significantly higher than control group (P＜0.05).
Aspect sperm concentration, the sperm motility of control group is the poorest; Test 3 groups best, and significantly be better than other three groups (P＜0.05); Test 1 group and the test 2 groups of sperm motilities also be significantly higher than control group (P＜0.05).
Aspect sperm motility, the sperm concentration of control group is minimum; Test 3 groups suitable with 2 groups of tests, and significantly be better than other two groups (P＜0.05); Test 1 group of sperm concentration and also be significantly higher than control group (P＜0.05).
Aspect rate of teratosperm, three processed group significantly are lower than control group (P＜0.05).
Different additive sees Table 3 to the variation of each hormone in the serum.
The measurement result of each hormone in table 3 serum
Annotate: in the lowercase shoulder mark of each test data of same column, lowercase difference person, expression significant difference (P＜0.05); The identical person of lowercase, expression difference is remarkable (P＞0.05) not.
Three test group are compared with control group, and the testosterone concentration in the serum significantly all significantly rises (P＜0.05), show that the reduction of the testosterone concentration that three kinds of additives that experiment adopts cause summer high temperature has significant improvement effect.Wherein test 2, test 3 action effects significantly better than test 1, data show significant difference (P＜0.05).
Three processed group are compared with control group, and the T3 content in the serum has and raises but difference not significantly (P＞0.05) shows that three kinds of additives that experiment is adopted reduce no significant improvement effect to the T3 content that summer high temperature causes.
Three processed group are compared with control group, and the cortisol in the serum has and raises but difference not significantly (P＞0.05) shows that three kinds of additives that experiment is adopted reduce no significant improvement effect to the cortisol content that summer high temperature causes.
In sum, three kinds of anti-additives can improve remarkable heat stress buck serum testosterone content (P＜0.05), and improve T3, cortisol content aspect difference not remarkable (P＞0.05).
Claims (3)
1. anti-heat stress feed additive that improves the buck reproductive function, it is characterized in that: keep requirement the adult rabbit of recommendation NRC (1977) and prepare in the basic diet feed, add the anti-heat stress additive, mix, the weight tons feed adds the anti-heat stress additive component and weight is: lipoic acid is that 100-800g, vitamin E are that 100-600g, vitamin C are that 100-600g and saccharicter-penin are 0-600g.
2. anti-heat stress feed additive according to claim 1 is characterized in that: described interpolation anti-heat stress additive component III and weight are that lipoic acid is that 600g, vitamin E are that 300g and vitamin C are 300g.
3. anti-heat stress feed additive according to claim 1, it is characterized in that: the method for breeding of buck is to raise buck at summer high-temperature, need surrounding enviroment, rabbit house, raise the instrument disinfection, buck is placed on same indoor single cage and raises, feed by the special messenger, sooner or later respectively feed the feed 1 time that adds the anti-heat stress additive every day, freely drink water, every day additional abundance green grass.
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| CN105166418A (en) * | 2015-10-13 | 2015-12-23 | 临沂大学 | Anti-heat stress feed additives for rabbits and preparation method thereof |
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| CN104206744A (en) * | 2014-09-26 | 2014-12-17 | 江苏农林职业技术学院 | Antioxidant feed additive and application thereof |
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| CN105309841A (en) * | 2015-10-28 | 2016-02-10 | 湛江粤华水产饲料有限公司 | Expanded feed capable of improving trachinotus ovatus meat quality and preparation method for expanded feed |
| CN105211501A (en) * | 2015-11-02 | 2016-01-06 | 山东贝瑞康生物科技有限公司 | A kind of health-care agent improving fur-bearing animal anti-stress ability |
| CN107647115A (en) * | 2017-10-12 | 2018-02-02 | 亚太星原农牧科技海安有限公司 | A kind of feed addictive of anti-heat stress and preparation method and application |
| CN113545424A (en) * | 2021-07-29 | 2021-10-26 | 山东省农业科学院畜牧兽医研究所 | Production method of functional rabbit meat product |
| CN116172128A (en) * | 2022-09-08 | 2023-05-30 | 南京农业大学 | Composite feed additive for improving and protecting fertility of middle-aged and old male animals |
| CN116172128B (en) * | 2022-09-08 | 2024-03-15 | 南京农业大学 | Composite feed additive for improving and protecting fertility of middle-aged and old male animals |
| CN116036157A (en) * | 2023-02-24 | 2023-05-02 | 四川省畜牧科学研究院 | Composition for resisting heat stress of male breeding rabbits and application thereof |
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