CN104206744A - Antioxidant feed additive and application thereof - Google Patents
Antioxidant feed additive and application thereof Download PDFInfo
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- CN104206744A CN104206744A CN201410500809.0A CN201410500809A CN104206744A CN 104206744 A CN104206744 A CN 104206744A CN 201410500809 A CN201410500809 A CN 201410500809A CN 104206744 A CN104206744 A CN 104206744A
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Abstract
The invention discloses an antioxidant feed additive. The antioxidant feed additive is composed of, by weight parts, 5-25 parts of vitamin E, 1.5-2.5 parts of vitamin C, 15-40 parts of alpha-lipoic acid and 32.5-78.5 parts of corn starch. The invention also discloses application of the antioxidant feed additive. The antioxidant feed additive can be widely applied to feedstuff and is added into livestock feedstuff at a proportion of 0.2%, thereby improving the organic antioxidant capacity and reducing oxidative stress and oxidative damage during a livestock breeding process, and further guaranteeing viability and completeness of cells and facilitating organic health maintenance of animals and high yield.
Description
Technical field
The present invention relates to a kind of fowl poultry kind feed addictive, relate in particular to a kind of antioxidant feed additive and application thereof.
Background technology
Animal body is under normal physiological status, and oxygen radical constantly produces, and is also constantly being eliminated simultaneously, and therefore, in animal body, oxygen radical maintains a lower level always, can not have a negative impact to body.But many poised states exogenous or that endogenous stimulus all can make vivo oxidation reduce are broken and tend to oxidation, and the growing amount of oxygen radical increases considerably, and shows the great detrimental effect of body.Oxidative stress usually can bring livestock and poultry production performance to decline, and animal product quality declines, and the problems such as Animal diseases even occur.In animal feeding, keep Free radical homeostasis to be considered to maintain under intensive management condition an important method of the good production of livestock and poultry and reproductive performance with antioxidant.
Absorptivity is not high for some antioxidants (butylated hydroxy anisole, dibutyl hydroxy toluene, n-propyl gallate, sodium isoascorbate etc.), poor stability, sphere of action are limited, and has certain Side effect.Lipoic acid (LA) easily absorbs, and can pass through stomach, small intestine and colon many places and absorb after administration; In structure, contain carboxyl and it can be soluble in the aqueous phase and can be dissolved in lipid, during all parts that make it can enter cell are gone and free radical; LA and dihydrolipoic acid (DHLA) can mutually supplement, mutually coordinate in vivo, bring into play efficient antioxidation; LA can form the anti-oxidant circulation in a body with VC, VE.Therefore, there is higher non-oxidizability compared with other antioxidant.
Summary of the invention
Goal of the invention: the object of this invention is to provide a kind of antioxidant feed additive composition, for improving resistivity and the removing ability of livestock and poultry to free radical; Another object of the present invention is to provide the application of a kind of oxidation resisting feedstuff on fattening pannage.
Technical scheme: for achieving the above object, a kind of antioxidant feed additive of the present invention, described feed addictive comprises following component by weight: vitamin E 5-25 part, vitamin C 1.5-2.5 part, alpha-lipoic acid 15-40 part, cornstarch 32.5-78.5 part.
As preferably, described feed addictive comprises following component by weight: 20 parts of vitamin Es, 2 parts of vitamin Cs, 30 parts of alpha-lipoic acids, 48 parts of cornstarch.
As preferably, described feed addictive comprises following component by weight: 25 parts of vitamin Es, 2.5 parts of vitamin Cs, 40 parts of alpha-lipoic acids, 32.5 parts of cornstarch.
As preferably, described feed addictive comprises following component by weight: 5 parts of vitamin Es, 1.5 parts of vitamin Cs, 15 parts of alpha-lipoic acids, 78.5 parts of cornstarch.
The application of above-mentioned a kind of antioxidant feed additive in preparation livestock and poultry diet.
Above-mentioned application, in livestock and poultry diet, add 0.2% described in feed addictive.
Beneficial effect: a kind of antioxidant feed additive of the present invention can be widely used in feed addictive, improve antioxidant ability of organism, reduce oxidative stress and oxidative damage in livestock and poultry cultivation process, thereby ensure vigor and the integrality of cell, be conducive to animal and maintain body health and high yield.
Detailed description of the invention
Below in conjunction with specific embodiment, further illustrate the present invention.
Embodiment 1
A kind of antioxidant feed additive, described feed addictive comprises following component by weight: 5 parts of vitamin Es, 1.5 parts of vitamin Cs, 15 parts of alpha-lipoic acids, 78.5 parts of cornstarch.Above-mentioned feed addictive is added in daily ration according to 0.2%, after fully stirring and evenly mixing, can feed.
Embodiment 2
A kind of antioxidant feed additive, described feed addictive comprises following component by weight: 20 parts of vitamin Es, 2 parts of vitamin Cs, 30 parts of alpha-lipoic acids, 48 parts of cornstarch.Above-mentioned feed addictive is added in daily ration according to 0.2%, after fully stirring and evenly mixing, can feed.
Embodiment 3
A kind of antioxidant feed additive, described feed addictive comprises following component by weight: 25 parts of vitamin Es, 2.5 parts of vitamin Cs, 40 parts of alpha-lipoic acids, 32.5 parts of cornstarch.Above-mentioned feed addictive is added in daily ration according to 0.2%, after fully stirring and evenly mixing, can feed.
test example adopts the feed of above-described embodiment 1, embodiment 2, the example 3 additives growing and fattening pigs effect of feeding
1, materials and methods
1.1 experimental animals and method: be that the healthy tri-crossbreeding of 80 kg is divided into 4 processed group, every group of 3 repetitions, 6 of each repetitions at random by 72 average weights.Control group fed basis diet, test group 1, test group 2 and test group 3 are added respectively 0.2% embodiment 1, embodiment 2 and the antioxidant feed additive of example 3 in basic diet, and feeding period is 35d.Adopt corn-soybean meal basis diet, prepare with reference to NRC pig nutrition requirements in 1998.
1.2 feedings and managements: whole feeding process is fed by same poultry raiser, Manual material feeding, free choice feeding, freely drinks water, and each group all gives identical feeding and management and environmental condition, if test group pig is ill in process of the test, by former therapeutic scheme treatment.
1.3 observation index: test pig is weighed after 16 h when just the examination phase starts and finishes on an empty stomach, statistics respectively repeats the feed consumption of pig at duration of test, calculates average daily ingestion amount, average daily gain and material anharmonic ratio.Off-test is each from each repetition chooses 2 test pig at random, vena cava anterior blood sampling 10ml, leave standstill in ice chest after 30min, centrifugal 10min under rotating speed 4000 r/min conditions, separation of serum is preserved the standby Antioxidant Indexes (comprising SOD, GSH-Px, MDA, T-AOC) of surveying in-70 DEG C of refrigerators.Adopt Nanjing to build up Bioengineering Research Institute's kit, by specification carries out; All indexs all with the long ELIASA of PowerWave XS type all-wave with colorimetric method for determining.
2, result of the test
The impact of table 1 antioxidant on Performance of Finishing Pigs
| Project | Control group | Test group 1 | Test group 2 | Test group 3 |
| Average daily ingestion amount/kg | 2506.2 | 2431.4 | 2398.1 | 2386.5 |
| Average daily gain/g | 735.3 | 752.8 | 766.5 | 757.6 |
| Material anharmonic ratio | 3.41 | 3.23 | 3.13 | 3.15 |
As shown in Table 1, compared with control group, test group 1, test group 2 and test group 3 daily gains be you can well imagine high 2.37%(P>0.05 than contrast components), 4.24%(P>0.05) and 3.03%(P>0.05), test group 1, test group 2 and test group 3 material anharmonic ratioes do not reduce 5.27%(P < 0.05 than contrast components), 8.21%(P < 0.05) and 7.62%(P < 0.05).
The impact of table 2 antioxidant on growing and fattening pigs Serum antioxidant indices
| Project | Control group | Test group 1 | Test group 2 | Test group 3 |
| Superoxide dismutase/Uml -1 | 118 | 127 | 131 | 134 |
| Glutathione peroxidase/Uml -1 | 658 | 897 | 1028 | 1026 |
| TAC/Uml -1 | 3.14 | 3.39 | 3.81 | 3.92 |
| MDA/nmolml -1 | 4.92 | 3.73 | 3.54 | 3.47 |
As shown in Table 2, compared with control group, test group 1, test group 2, test group 3 serum superoxide dismutases activity have improved respectively 7.6%(
p< 0.05), 11.0%(P < 0.01) and 13.6%(P < 0.01); Serum activity of glutathione peroxidase has improved respectively 36.3%(P<0.01), 56.2%(P<0.01) and 55.9%(P<0.01), wherein test group 2 and test group 3 have improved respectively 14.6%(P < 0.05 than test group 1) and 14.4%(P < 0.05); Serum TAC you can well imagine 7.96 %(P < 0.05 high than contrast component respectively), 21.33 %(P<0.01) and 24.84 %(P<0.01); Serum MDA content is compared with control group, and 24.18%(P<0.01 has declined respectively), 28.05%(P<0.01) and 29.47%(P<0.01).
Illustrate by above test example, antioxidant feed additive provided by the invention can significantly reduce material anharmonic ratio, improves antioxidant ability of organism, thereby reduces oxidative stress and oxidative damage in livestock and poultry cultivation process.
Claims (6)
1.
oneplant antioxidant feed additive, it is characterized in that, described feed addictive comprises following component by weight: vitamin E 5-25 part, vitamin C 1.5-2.5 part, alpha-lipoic acid 15-40 part, cornstarch 32.5-78.5 part.
2. a kind of antioxidant feed additive according to claim 1, is characterized in that, described feed addictive comprises following component by weight: 20 parts of vitamin Es, 2 parts of vitamin Cs, 30 parts of alpha-lipoic acids, 48 parts of cornstarch.
3. a kind of antioxidant feed additive according to claim 1, is characterized in that, described feed addictive comprises following component by weight: 25 parts of vitamin Es, 2.5 parts of vitamin Cs, 40 parts of alpha-lipoic acids, 32.5 parts of cornstarch.
4. a kind of antioxidant feed additive according to claim 1, is characterized in that, described feed addictive comprises following component by weight: 5 parts of vitamin Es, 1.5 parts of vitamin Cs, 15 parts of alpha-lipoic acids, 78.5 parts of cornstarch.
5. the application of a kind of antioxidant feed additive claimed in claim 1 in preparation livestock and poultry diet.
6. application according to claim 3, is characterized in that, in livestock and poultry diet, add 0.2% described in feed addictive.
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| CN201410500809.0A CN104206744A (en) | 2014-09-26 | 2014-09-26 | Antioxidant feed additive and application thereof |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105053640A (en) * | 2015-08-06 | 2015-11-18 | 张剑逸 | Antioxidation broiler chicken feed additive and application thereof |
| CN105533166A (en) * | 2016-01-19 | 2016-05-04 | 安徽农业大学 | Feed additive for enhancing pig body oxidative stress resistance and improving meat quality and use method of feed additive |
| CN106138037A (en) * | 2016-08-24 | 2016-11-23 | 江苏农林职业技术学院 | The compositions of a kind of antibiont cell oxidative damage and application thereof |
| CN108294165A (en) * | 2017-12-23 | 2018-07-20 | 青岛麦迪尔生物工程有限公司 | A kind of antioxidant feed additive and preparation method thereof |
| CN111227120A (en) * | 2020-03-14 | 2020-06-05 | 安徽安宠宠物用品有限公司 | Combined antioxidant for pets |
| CN111567683A (en) * | 2020-06-24 | 2020-08-25 | 广东海洋大学 | Fish feed additive for improving antioxidant function |
| CN111743035A (en) * | 2020-06-24 | 2020-10-09 | 广东海洋大学 | Fish feed additive for improving antioxidant function |
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| CN105053640A (en) * | 2015-08-06 | 2015-11-18 | 张剑逸 | Antioxidation broiler chicken feed additive and application thereof |
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| CN111743035A (en) * | 2020-06-24 | 2020-10-09 | 广东海洋大学 | Fish feed additive for improving antioxidant function |
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