CN101966077A - Multi-angle imaging device - Google Patents

Multi-angle imaging device Download PDF

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Publication number
CN101966077A
CN101966077A CN 201010131799 CN201010131799A CN101966077A CN 101966077 A CN101966077 A CN 101966077A CN 201010131799 CN201010131799 CN 201010131799 CN 201010131799 A CN201010131799 A CN 201010131799A CN 101966077 A CN101966077 A CN 101966077A
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CN
China
Prior art keywords
imaging device
plane
angle
camera
angle imaging
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Pending
Application number
CN 201010131799
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Chinese (zh)
Inventor
田捷
高秋娟
杨鑫
杨祥
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Guangzhou Zhongke Kaisheng Medical Technology Co Ltd
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Guangzhou Zhongke Kaisheng Medical Technology Co Ltd
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Application filed by Guangzhou Zhongke Kaisheng Medical Technology Co Ltd filed Critical Guangzhou Zhongke Kaisheng Medical Technology Co Ltd
Priority to CN 201010131799 priority Critical patent/CN101966077A/en
Publication of CN101966077A publication Critical patent/CN101966077A/en
Pending legal-status Critical Current

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Abstract

The invention provides a multi-angle imaging device which comprises a plane reflecting mirror set, an objective table and a camera, wherein the plane reflecting mirror set consists of two plane reflecting mirrors, and the reflecting surfaces of the two plane reflecting mirrors form an angle of 90 degrees and are respectively placed by forming an angle of 45 degrees with a desktop; the objective table is arranged between the two plane reflecting mirrors, and an object is put on the objective table; and three surface images of the object can be obtained by using the camera to once shoot from top to bottom, thereby the relative motion and the deformation of the object, which are generated by sequentially shooting each side surface of the object, are avoided, and the shooting time is avoided. The invention has the advantages of simple design structure, low cost, small volume and portability, is convenient to operate, and can be applied to the field of medical images, and the like.

Description

The multi-angle imaging device
Technical field
The present invention relates to a kind of multi-angle imaging device, exactly, relate to a kind of device that utilizes plane mirror to object a plurality of sides imaging, this device can be used to obtain three-dimensional object surface information.
Background technology
Along with developing rapidly of genomics, protein science and disease gene group, the diagnosis of disease is characterizing from traditional disease and is observing, conventional biochemical test detects, develop into the microscopic feature understanding of several genes and molecular level, wherein utilize the molecular image technology can be from generation, the evolution of gene, protein level heightened awareness disease, can realize integral body, continuous, noninvasive special detection method that existing micro analysis institute can't replace, biology will provide brand-new prevention, diagnosis and treatment means in body molecular image theory and technology thereof.With traditional medical image technology comparatively speaking, the basis that molecular imaging is conceived to constitute disease or pathological changes changes and gene molecule level unusual, rather than the final result that is made of the gene molecule change is carried out imaging.Under the help of special molecular probe, the molecular image technology can realize the noinvasive Real-time and Dynamic imaging in vivo of organism internal physiological or pathological process on cell, gene and molecular level, thus for researchs such as the mechanism of action of disease related gene functional localization, cell growth promoter and mutation process, new drug development provide detailed qualitative, location, quantitative data and effectively information obtain means with analyzing and processing.
The autofluorescence tomography technology is the emerging in recent years interior optical molecular image technology of living animal body.Archebiosis fluorescence is with luciferase gene labeled cell or DNA, and the Fluc gene integration is gone up with expressing luciferase to cell chromosome DNA.Under the situation that ATP and oxygen exist, if inject the substrate fluorescein to living animal, the oxidation reaction that luciferase will the catalysis fluorescein also produces photon.External at living animal, utilize highly sensitive optical detecting instrument, can directly capture the outer photon of effusion animal body, utilize effective fluorescence light source algorithm for reconstructing then, just can obtain the position and the intensity of fluorescence light source in the body, and then can observe intravital cell behavior of living animal and gene behavior.
In order as often as possible to obtain overflowing the outer photon information of animal body, need carry out imaging to the three-dimensional surface of animal body with photoelectric detector.At present, the method of utilizing plane mirror to obtain the three-dimensional surface information of animal body has a lot, a kind of method is for using and object plane mirror at 45, successively to the object side surface imaging, this quadrat method has many drawbacks, as: every shooting is once, all to adjust the relative position of primary event mirror and object, so not only the operation trouble is lost time again, the relative position of object changes again easily, to realizing that image Reconstruction has increased adverse factors, and the optical information on animal body surface is along with the time decay, and this reconstruction error is just bigger.A kind of method is for using four plane mirrors, be placed on around the object, and with object angle at 45, obtain four profiles of object simultaneously, the shortcoming of this method is that the picture that becomes on CCD of object is little, and reconstruction error is big, and the image of CCD last 3/4 and body surface information are irrelevant, caused insufficient utilization of CCD, the waste resource.A kind of method is taken pictures to around the object simultaneously for using four cameras, increased the expense of equipment like this, and the performance of four cameras is incomplete same, has increased the error of rebuilding.
Three-dimensional imaging data acquisition device involved in the present invention just can obtain three surface informations of object by using a camera once photo taking, and the image of three faces is form side by side, has increased the utilization rate of CCD.
Summary of the invention
The objective of the invention is to overcome the drawback of existing mirror imaging system, provide a kind of and both saved time, can make full use of CCD again, simple, convenient multi-angle imaging device.
For achieving the above object, the present invention adopts following technical scheme: a kind of multi-angle imaging device includes: plane mirror group, object stage and camera, as shown in Figure 1, camera is positioned at the top of plane mirror group.Wherein camera is a kind of photodetector, the plane mirror group comprises two plane mirrors, two plane mirrors are positioned over the testee left and right sides, reflecting surface at an angle of 90, and respectively with horizontal plane angle at 45, object stage is positioned in the middle of two plane mirrors, object is placed on the object stage, two plane mirrors are identical with the testee distance, can obtain three surperficial pictures of testee by once photo taking, it is characterized in that, the petty action object that body is contained fluorescence light source is put in the position of testee 5 among Fig. 1, the petty action object is placed perpendicular to paper, and be positioned at the centre of plane mirror 2 and plane mirror 3, its back picture is directly taken by camera and is obtained, and its left surface is by plane mirror 2 imagings, right flank is once taken and can be obtained back picture and left and right side picture simultaneously by plane mirror 3 imagings.
The invention has the beneficial effects as follows: by once taking the fluorescence information just can obtain three faces of testee, save time, and fluorescence information is to obtain at one time there is not the influence of fluorescence decay; The image of each three faces that obtain measured object is form side by side, has made full use of the area of CCD; It is simple and convenient to take pictures.Information according to three surfaces of measured object that obtain, utilize the fluorescence light source algorithm for reconstructing, can rebuild accurately the position and the intensity of biological tissue's inside fluorescence light source, be the early diagnosis and the early treatment of disease, that the evaluation of curative effect of medication provides is qualitative accurately, location, quantitative data.
Description of drawings
Fig. 1 is the sketch map of multi-angle imaging device.
Fig. 2 is the schematic diagram of multi-angle imaging device.
Fig. 3 is back and the left and right sides image sketch map that once photo taking obtains.
The specific embodiment
The present invention is further described below in conjunction with drawings and Examples.As shown in Figure 1, the toy 5 that body is contained fluorescence light source is placed on the object stage 4 perpendicular to paper, and plane mirror 2 and plane mirror 3 lay respectively at the left and right sides of petty action object, and reflecting surface is vertical, object stage is positioned in the middle of two plane mirrors, and camera 1 is taken pictures from the top down.Fig. 2 is the schematic diagram of multi-angle imaging device.The left surface 6 of petty action object by plane mirror 2 be imaged as left surface as 6 ', directly imaging in camera of toy back 7, toy right flank 8 by plane mirror 3 be imaged as right flank as 8 ', like this, camera can obtain left surface picture, back picture and the right flank picture of toy simultaneously in once photo taking.Fig. 3 is back and the left and right sides image sketch map that once photo taking obtains.9 is ccd detector, 6 ' be the left surface picture, 7 is the back picture, 8 ' be petty action object right flank picture.

Claims (5)

1. multi-angle imaging device, include: plane mirror group, object stage and camera, plane mirror group comprise two plane plane mirrors; It is characterized in that: described testee is positioned on the object stage perpendicular to paper, two plane mirror reflectings surface at an angle of 90, object stage is positioned in the middle of two plane mirrors, can obtain three of testees surface picture by once photo taking.
2. multi-angle imaging device as claimed in claim 1 is characterized in that camera is a kind of photodetector.
3. multi-angle imaging device as claimed in claim 1 is characterized in that two plane mirrors are positioned over the testee left and right sides, respectively with horizontal plane angle at 45.
4. multi-angle imaging device as claimed in claim 1 is characterized in that two plane mirrors are identical with the testee distance.
5. multi-angle imaging device as claimed in claim 1 is characterized in that camera is positioned at the top of plane mirror group.
CN 201010131799 2010-03-25 2010-03-25 Multi-angle imaging device Pending CN101966077A (en)

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104296679A (en) * 2014-09-30 2015-01-21 唐春晓 Mirror image type three-dimensional information acquisition device and method
CN105973165A (en) * 2015-06-10 2016-09-28 北京领邦仪器技术有限公司 Single-camera three-dimensional image measuring instrument
CN109357121A (en) * 2018-09-17 2019-02-19 南京家泉烟草机械配件有限公司 The fixation device of the image pickup method of Polaroid multi-panel and object to be clapped
CN110824684A (en) * 2019-10-28 2020-02-21 华中科技大学 High-speed three-dimensional multi-modal imaging system and method
CN111060001A (en) * 2019-12-27 2020-04-24 广州彩虹五金弹簧有限公司 Measuring device and measuring method for special-shaped spring dispersed target points
CN111121624A (en) * 2019-12-27 2020-05-08 广东工业大学 System for measuring dispersed target point of special-shaped spring based on single camera
CN114019760A (en) * 2021-11-16 2022-02-08 中国科学院长春光学精密机械与物理研究所 Biological light-emitting multiband three-dimensional imaging system for living bodies of small animals

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999036881A1 (en) * 1998-01-16 1999-07-22 Beaty Elwin M Method and apparatus for three-dimensional inspection of electronic components
CN2508644Y (en) * 2001-03-28 2002-09-04 孙占强 Multi-part dressing mirror capable of seeing back of body
US20030072011A1 (en) * 2001-10-09 2003-04-17 Shirley Lyle G. Method and apparatus for combining views in three-dimensional surface profiling
CN201683880U (en) * 2010-03-25 2010-12-29 田捷 Multi-angle imaging device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999036881A1 (en) * 1998-01-16 1999-07-22 Beaty Elwin M Method and apparatus for three-dimensional inspection of electronic components
CN2508644Y (en) * 2001-03-28 2002-09-04 孙占强 Multi-part dressing mirror capable of seeing back of body
US20030072011A1 (en) * 2001-10-09 2003-04-17 Shirley Lyle G. Method and apparatus for combining views in three-dimensional surface profiling
CN201683880U (en) * 2010-03-25 2010-12-29 田捷 Multi-angle imaging device

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104296679A (en) * 2014-09-30 2015-01-21 唐春晓 Mirror image type three-dimensional information acquisition device and method
CN105973165A (en) * 2015-06-10 2016-09-28 北京领邦仪器技术有限公司 Single-camera three-dimensional image measuring instrument
CN109357121A (en) * 2018-09-17 2019-02-19 南京家泉烟草机械配件有限公司 The fixation device of the image pickup method of Polaroid multi-panel and object to be clapped
CN110824684A (en) * 2019-10-28 2020-02-21 华中科技大学 High-speed three-dimensional multi-modal imaging system and method
CN110824684B (en) * 2019-10-28 2020-10-30 华中科技大学 High-speed three-dimensional multi-modal imaging system and method
CN111060001A (en) * 2019-12-27 2020-04-24 广州彩虹五金弹簧有限公司 Measuring device and measuring method for special-shaped spring dispersed target points
CN111121624A (en) * 2019-12-27 2020-05-08 广东工业大学 System for measuring dispersed target point of special-shaped spring based on single camera
CN114019760A (en) * 2021-11-16 2022-02-08 中国科学院长春光学精密机械与物理研究所 Biological light-emitting multiband three-dimensional imaging system for living bodies of small animals

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Application publication date: 20110209