CN101940692A - Chinese medicinal composition for treating enterovirus syndrome in Dorking and preparation method thereof - Google Patents
Chinese medicinal composition for treating enterovirus syndrome in Dorking and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition, in particular to a Chinese medicinal composition for treating enterovirus syndrome in Dorking and a preparation method thereof. The Chinese medicinal composition for treating the enterovirus syndrome in the Dorking is characterized by consisting of the following components: baical skullcap root, golden thread, bighead atractylodes rhizome, Indian buead, dried tangerine peel, yam, astragalus, codonopsis pilosula and skunk bugbane. The Chinese medicinal composition is specially used for treating the enterovirus syndrome in the Dorking, wherein the baical skullcap root and the golden thread for removing heat and drying damp, and purging intense heat and detonicating are primary medicaments; the bighead atractylodes and the Indian buead for invigorating spleen and replenishing vital energy, and the dried tangerine peel and the yam for regulating vital energy to eliminate damp are adjuvant medicaments; the astragalus and the codonopsis pilosulaare for replenishing vital energy to ascend lucidity and invigorating the spleen to arrest diarrhea are adjuvant medicaments; and the skunk bugbane introduces the medicaments to directly achieve the affected area, and is a conductant medicament. The toxic and side effect of the Chinese medicinal composition is greatly reduced, and the problem of medicament residue does not exist.
Description
(1) technical field
The present invention relates to a kind of Chinese medicine composition, particularly a kind of Chinese medicine composition for the treatment of enterotoxic syndrome of meat chicken and preparation method thereof.
(2) background technology
Enterotoxic syndrome of meat chicken is the ubiquitous a kind of disease of commercial meat bird group, its symptom is: diarrhoea, contain in the feces feedstuff that do not have digestion good, feed intake obviously decline, poor growth or lose weight, dehydration etc., this symptom is often thought general dyspepsia mistakenly by the feeding of broiler family, or single small intestinal coccidium infection, in fact it is a kind of syndrome that is caused by Different types of etiopathogenises such as small intestinal coccidiosis, anaerobe, viruses.At present, this kind disease is generally popular, though mortality rate is not high, the stealthy economic loss that causes is huge.Because this disease cause of disease complexity is various, brings great difficulty to clinical treatment.
(3) summary of the invention
The present invention provides a kind of curative effect height, has been specifically designed to Chinese medicine composition of treatment enterotoxic syndrome of meat chicken and preparation method thereof in order to remedy the deficiencies in the prior art.
The present invention is achieved through the following technical solutions:
A kind of Chinese medicine composition for the treatment of enterotoxic syndrome of meat chicken, its special character is: the component by following parts by weight is made:
Radix Scutellariae 5-7 part Rhizoma Coptidis 5-7 part Rhizoma Atractylodis Macrocephalae 4-6 part
Poria 4-6 part Pericarpium Citri Reticulatae 5-7 part Rhizoma Dioscoreae 5-7 part
Radix Astragali 5-7 part Radix Codonopsis 4-6 part Rhizoma Cimicifugae 3-5 part.
The present invention treats the Chinese medicine composition of enterotoxic syndrome of meat chicken, and its preferred scheme is: the component by following parts by weight is made:
5 parts of 6 parts of Rhizoma Atractylodis Macrocephalaes of 6 portions of Rhizoma Coptidis of Radix Scutellariae
6 parts of 6 portions of Rhizoma Dioscoreaes of 5 parts of Pericarpium Citri Reticulataes of Poria
4 parts of 5 parts of Rhizoma Cimicifugaes of 6 parts of Radix Codonopsis of the Radix Astragali.
The present invention treats the preparation method of the Chinese medicine composition of enterotoxic syndrome of meat chicken, comprises the steps:
(1) take by weighing each crude drug Radix Scutellariae, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Poria, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, the Radix Astragali, Radix Codonopsis, Rhizoma Cimicifugae, standby behind the decontamination;
(2) with the above-mentioned raw materials medicine mixing of described parts by weight, add super micron mill 300 and pulverize now, the medicine of pulverizing was soaked in water 50 minutes-70 minutes;
(3) soaked medicine is put into the microwave extracting machine under 480 watts power microwave 5-7 minute, put into Rotary Evaporators then under 75 ℃ of-85 ℃ of conditions dry 8-10 minute, pulverize at last and be finished product.
Instructions of taking: according to mass fraction is that 0.1% ratio is admixed and thrown something and fed in the feedstuff or be that 0.05% ratio is admixed in the drinking water according to mass fraction.
Chinese medicine composition of the present invention is specifically designed to the treatment enterotoxic syndrome of meat chicken, cause the cause of disease of intestinal toxicity syndrome a lot, comprising small intestinal coccidiosis, bacterial infection, viral infection, alteration of intestinal flora etc., rely on the folk prescription medicine to be difficult to be effectively controlled clinically, Chinese medicine composition of the present invention selects for use plurality of Chinese to carry out the science compatibility, Radix Scutellariae, Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication are principal agent; The Rhizoma Atractylodis Macrocephalae, Poria invigorating the spleen and benefiting QI, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae regulating QI to expel dampness are accessory drugs; The Radix Astragali, Radix Codonopsis are with the QI invigorating the lucid yang sending up, and invigorating the spleen to arrest diarrhea is an adjuvant drug; Rhizoma Cimicifugae draws the through sick institute of all medicines, is messenger drug.Chinese medicine composition toxic and side effects of the present invention reduces greatly, does not also have the problem of drug residue simultaneously.
(4) specific embodiment
Embodiment 1:
The preparation method of the Chinese medicine composition of treatment enterotoxic syndrome of meat chicken, adopt following steps:
(1) take by weighing Radix Scutellariae 30 grams, Rhizoma Coptidis 30 grams, the Rhizoma Atractylodis Macrocephalae 25 grams, Poria 25 grams, Pericarpium Citri Reticulatae 30 grams, Rhizoma Dioscoreae 30 grams, the Radix Astragali 30 grams, Radix Codonopsis 25 grams, Rhizoma Cimicifugae 20 grams, standby behind the decontamination;
(2) with above-mentioned raw materials medicine mixing, add super micron mill 300 and pulverize now, the medicine of pulverizing was soaked in water 60 minutes;
(3) soaked medicine is put into microwave extracting machine microwave 6 minutes under 480 watts power, put into Rotary Evaporators then under 80 ℃ of conditions dry 9 minutes, pulverize at last and be finished product.
Instructions of taking: according to mass fraction is that 0.1% ratio is admixed and thrown something and fed in the feedstuff or be that 0.05% ratio is admixed in the drinking water according to mass fraction.
Embodiment 2:
The Chinese medicine composition of this treatment enterotoxic syndrome of meat chicken is made by the component of following weight: Radix Scutellariae 25 grams, Rhizoma Coptidis 25 grams, the Rhizoma Atractylodis Macrocephalae 20 grams, Poria 20 grams, Pericarpium Citri Reticulatae 25 grams, Rhizoma Dioscoreae 25 grams, the Radix Astragali 25 grams, Radix Codonopsis 20 grams, Rhizoma Cimicifugae 15 grams.
Embodiment 3:
The Chinese medicine composition of this treatment enterotoxic syndrome of meat chicken is made by the component of following weight: Radix Scutellariae 35 grams, Rhizoma Coptidis 35 grams, the Rhizoma Atractylodis Macrocephalae 30 grams, Poria 30 grams, Pericarpium Citri Reticulatae 35 grams, Rhizoma Dioscoreae 35 grams, the Radix Astragali 35 grams, Radix Codonopsis 30 grams, Rhizoma Cimicifugae 25 grams.
Embodiment 4: test effect is observed
Carried out animal experiment according to Ministry of Agriculture's " experiment clinical trial technical specification " [No. the 99th, (1992) farming (herding medicine) word], test situation is reported as follows:
(1) test drug: the Chinese medicine composition of the treatment enterotoxic syndrome of meat chicken that the embodiment of the invention 1 is made is that 0.05% ratio joins in the drinking water according to mass fraction;
The contrast medicine: Maduramicin, available from Zhejiang Kangyu Pharmaceutical Co., Ltd.;
Sulphaquinoxaline is available from the Huangyan, Zhejiang chemical plant;
Amprolium is available from the biochemical company limited in auspicious field;
(2) experimental animal: because the cause of disease of intestinal toxicity syndrome is various, be difficult in and copy this disease animal model under the laboratory condition, according to the diagnosis of clinical symptoms and laboratory detection method to clinical case, selected for use districts and cities such as Liaocheng, Dezhou, Jinan to be diagnosed as 5 chicken groups (20 hen houses, about 100,000 chickens) of intestinal toxicity syndrome as experimental animal year October in July, 2009-2009;
(3) curative effect determinate standard:
After the dispensing, the natural law of transference cure; Dead number of elements; Offer medicine chicken after 3,5,7 days cut open the inspection pathological change and the histology changes the therapeutic effect of judging medicine.
Result of the test: see Table 1
The Chinese medicine composition (hereinafter to be referred as Chinese medicine composition of the present invention) of the treatment enterotoxic syndrome of meat chicken that table 1 embodiment of the invention 1 is made is to the therapeutic effect of intestinal toxicity syndrome
As can be seen from Table 1, the embodiment of the invention 1 made Chinese medicine composition all has the good curing effect to 5 chicken groups that are diagnosed as intestinal toxicity syndrome, treatment cycle is short, mortality rate is low, chicken the group recover, and other contrast medicines of selecting for use, therapeutic effect is relatively poor, especially to the 1 chicken group that helps, contrast the readily good substantially therapeutic effect of medicine.
Claims (3)
1. Chinese medicine composition for the treatment of enterotoxic syndrome of meat chicken, it is characterized in that: the component by following parts by weight is made:
Radix Scutellariae 5-7 part Rhizoma Coptidis 5-7 part Rhizoma Atractylodis Macrocephalae 4-6 part
Poria 4-6 part Pericarpium Citri Reticulatae 5-7 part Rhizoma Dioscoreae 5-7 part
Radix Astragali 5-7 part Radix Codonopsis 4-6 part Rhizoma Cimicifugae 3-5 part.
2. the Chinese medicine composition of treatment enterotoxic syndrome of meat chicken according to claim 1 is characterized in that: the component by following parts by weight is made:
5 parts of 6 parts of Rhizoma Atractylodis Macrocephalaes of 6 portions of Rhizoma Coptidis of Radix Scutellariae
6 parts of 6 portions of Rhizoma Dioscoreaes of 5 parts of Pericarpium Citri Reticulataes of Poria
4 parts of 5 parts of Rhizoma Cimicifugaes of 6 parts of Radix Codonopsis of the Radix Astragali.
3. the preparation method of the Chinese medicine composition of treatment enterotoxic syndrome of meat chicken according to claim 1 is characterized in that: comprise the steps:
(1) take by weighing each crude drug Radix Scutellariae, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Poria, Pericarpium Citri Reticulatae, Rhizoma Dioscoreae, the Radix Astragali, Radix Codonopsis, Rhizoma Cimicifugae, standby behind the decontamination;
(2) with the above-mentioned raw materials medicine mixing of described parts by weight, add super micron mill 300 and pulverize now, the medicine of pulverizing was soaked in water 50 minutes-70 minutes;
(3) soaked medicine is put into the microwave extracting machine under 480 watts power microwave 5-7 minute, put into Rotary Evaporators then under 75 ℃ of-85 ℃ of conditions dry 8-10 minute, pulverize at last and be finished product.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102309563A (en) * | 2011-09-21 | 2012-01-11 | 河北征宇制药有限公司 | Medicinal preparation used for treating diarrhoea of livestock and poultry |
| CN103083427A (en) * | 2011-10-27 | 2013-05-08 | 天津生机集团股份有限公司 | Traditional Chinese medicine powder used for preventing and treating layer enterovirus syndrome |
| CN103393881A (en) * | 2013-07-30 | 2013-11-20 | 王旋旋 | Traditional Chinese medicine composition for treating rabbit diarrhea |
| CN106063913A (en) * | 2016-08-22 | 2016-11-02 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of Chinese medicine composition preventing and treating poultry enterotoxin syndrome and its preparation method and application |
| CN108126035A (en) * | 2017-01-16 | 2018-06-08 | 华南农业大学 | A kind of Chinese medicine composition for adjusting heat-stressed rats blood biochemistry and intestinal flora and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
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2010
- 2010-08-25 CN CN2010102616895A patent/CN101940692B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1380098A (en) * | 2002-05-20 | 2002-11-20 | 张勇飞 | Anti-infection compound preparation and its preparation method |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102309563A (en) * | 2011-09-21 | 2012-01-11 | 河北征宇制药有限公司 | Medicinal preparation used for treating diarrhoea of livestock and poultry |
| CN103083427A (en) * | 2011-10-27 | 2013-05-08 | 天津生机集团股份有限公司 | Traditional Chinese medicine powder used for preventing and treating layer enterovirus syndrome |
| CN103083427B (en) * | 2011-10-27 | 2016-08-03 | 天津生机集团股份有限公司 | A kind of Chinese powder medicine for preventing and treating laying hen intestinal toxicity syndrome |
| CN103393881A (en) * | 2013-07-30 | 2013-11-20 | 王旋旋 | Traditional Chinese medicine composition for treating rabbit diarrhea |
| CN106063913A (en) * | 2016-08-22 | 2016-11-02 | 中国农业科学院兰州畜牧与兽药研究所 | A kind of Chinese medicine composition preventing and treating poultry enterotoxin syndrome and its preparation method and application |
| CN108126035A (en) * | 2017-01-16 | 2018-06-08 | 华南农业大学 | A kind of Chinese medicine composition for adjusting heat-stressed rats blood biochemistry and intestinal flora and preparation method thereof |
| CN108126035B (en) * | 2017-01-16 | 2021-07-09 | 华南农业大学 | Traditional Chinese medicine composition for regulating blood biochemistry and intestinal flora of heat stress rats and preparation method thereof |
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| CN101940692B (en) | 2011-08-31 |
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