CN101919987A - Soft capsule for treating vagina - Google Patents

Soft capsule for treating vagina Download PDF

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Publication number
CN101919987A
CN101919987A CN2009100722295A CN200910072229A CN101919987A CN 101919987 A CN101919987 A CN 101919987A CN 2009100722295 A CN2009100722295 A CN 2009100722295A CN 200910072229 A CN200910072229 A CN 200910072229A CN 101919987 A CN101919987 A CN 101919987A
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CN
China
Prior art keywords
vagina
soft capsule
gram
treatment
capsule preparation
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Pending
Application number
CN2009100722295A
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Chinese (zh)
Inventor
夏秀蓝
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Individual
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Individual
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Priority to CN2009100722295A priority Critical patent/CN101919987A/en
Publication of CN101919987A publication Critical patent/CN101919987A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to a soft capsule preparation for treating the vagina, which comprises the following components in percentage by weight: 0.1-1% of polyhexamethylene guanide, 1-5% of chitin, 15-25% of oil of zedoary turmeric and balance of soybean oil. The capsule shell formula comprises 200-500g of gelatin, 100-400g of purified water, 50-300g of glycerol, 2-20g of ethylparaben, 2-20g of propylparaben, 20-80g of 9% ethanol and 3-15g of titanium dioxide. The prepared soft capsule can be taken as a product for treating the vagina, and an administration mode of directly pushing the soft capsule into the vagina is adopted. The invention has the characteristics of high effect taking speed, exact treatment effect, short treatment period, simple production process, low cost, safety, no toxicity, wide range of action and the like.

Description

A kind of soft capsule that is used for the treatment of vagina
Technical field
The present invention relates to a kind of product of medicine and hygiene fields, be specifically related to a kind of product for the treatment of vagina, relate to the preparation method of this kind product simultaneously.
Background technology
Vaginitis is the inflammation of connective tissue under vaginal mucosa and the mucosa, is the common disease of gynecological's outpatient service.Normal health women, because anatomy and biochemistry characteristics, vagina has the nature defense function to the intrusion of pathogen, when the natural defense function of vagina is destroyed, then pathogen is easy to invade, cause colpitis, youngest daughter and postmenopausal women are owing to estrogen deficiency, and vagina epithelium is poor, the former content of endocellular sugar reduces, vagina PH is up to about 7, and is so vagina is lower for the resistance, easily more infected than the adolescence and the women of child-bearing age.Vaginitis changes with the character of leucorrhea clinically and the pudendum infections is itched, and causalgia is main clinical characters, and sexual anhedonia is also common, infects when involving urethra, and symptoms such as dysurea, urgent micturition can be arranged.
At above symptom, adopt traditional therapeutic modality can not fundamentally treat above disease, content of the present invention uses with polyhexamethylene guanidine, chitin, Oleum Curcumae compatibility, through proportioning screening to prescription, and the softgel shell prescription furtherd investigate, adopt the administering mode that directly pushes vagina, through focus, discharge rapidly, succeeded in developing the prescription of the soft capsule preparation of novel therapeutic vagina.
Summary of the invention
The object of the present invention is to provide a kind of rapid-action, determined curative effect, treatment cycle is short, production process is simple, with low cost, safety non-toxic, the soft capsule preparation that is used for the treatment of vagina that sphere of action is wide.
The present invention realizes by following technical scheme:
The specific embodiment:
Adopting polyhexamethylene guanidine, chitin, Oleum Curcumae is the soft capsule preparation that content is made, its capsule skin constituent is: gelatin, purified water, glycerol, ethyl hydroxybenzoate, propyl p-hydroxybenzoate, 9% ethanol, titanium dioxide, adopt the administering mode that directly pushes vagina, be applied to treat vagina.Its guanidine radicals of hexa-methylene guanidine has very high activity in polyreaction, make polymeric derivative be electropositive, so be easy to be usually electronegative each bacterioid, viral adsorbed, thereby the splitting function that has suppressed antibacterial, virus, make antibacterial, virus lose reproductive function, the thin film of polymer formation has stopped up the respiration channel of microorganism in addition, makes microorganism suffocate the power of losing one's life and reaches sterilization effect.Chitin has the growth that promotes the enteral probiotics, keeps the effect of tract ecological balance, and has very strong antimicrbial power, can improve the function of calcium metabolism and the ability of cellular uptake calcium.Rhizoma Curcumae volatile oil can suppress the growth of staphylococcus aureus, beta hemolytic streptococcus, escherichia coli, Bacillus typhi, vibrio cholera etc.
Experiment showed, polyhexamethylene guanidine, chitin, Oleum Curcumae are used with the proper proportion compatibility, not only can make the complementary expansion of antimicrobial spectrum, also can strengthen fungistatic effect greatly because of its synergism.Adopt the administering mode directly push vagina, through focus, and developed the capsule skin prescription of science, and medicine is discharged rapidly, can regulate the intravaginal environment fast and effectively, thereby reach the purpose of treatment disease.
The present invention has the following advantages:
A, content prescription advanced person use polyhexamethylene guanide, chitin, oil of zedoary turmeric compatibility, have enlarged on the original basis antimicrobial spectrum, and greatly strengthen fungistatic effect because it acts synergistically.
B, capsule skin prescription is advanced, can not only reach quick dissolving, and ethyl hydroxy benzoate and propylparaben also have antisepsis, can effectively prolong shelf life of products.
C, production process are simple to operate, direct fill soft capsule, and technology is controlled easily, and constant product quality.
D, take specialized mode of production science to produce, with short production cycle, low cost of manufacture.
E, environment-friendly type preparation, production process do not use any toxin preparation that has, and no organic reagent is residual.
F, product biological activity are strong, and bactericidal effect is remarkable, does not produce drug resistance.
The present invention is the soft capsule preparation that content is made the novel therapeutic vagina with polyhexamethylene guanidine, chitin, Oleum Curcumae, adopts the administering mode that directly pushes vagina, through focus, and the capsule coupling of science is put the history medicine and is discharged rapidly, and extraordinary clinical efficacy is arranged.And confirm through domestic authoritative expert's demonstration and international medical community, have clear and definite scientific basis and definite curative effect, practical problems such as the medicine antibacterial spectrum was narrow in the past, side effect big, weak effect, pathogenic bacterium generation tolerance have fundamentally been changed, directly push the administering mode of vagina, through focus, and adopted advanced capsule skin prescription, medicine is discharged rapidly, can regulate the intravaginal environment fast and effectively, thereby reach the purpose of treatment disease.Product has characteristics such as fungicidal spectrum is wide, the lasting period is long, biological activity is strong, speed of action is fast, stable in properties, safety non-toxic, through evidence, can effectively kill a series of pathogenic microorganisms such as gold-coloured staphylococci, bacillus subtilis, escherichia coli, Candida albicans, fungus, mycete, virus.And make soft capsule be take into full account the patient easy to use, use rationally, will make this product have more the market competitiveness.

Claims (5)

1. soft capsule preparation that is used for the treatment of vagina.
2. effective ingredient and capsule skin prescription and the administering mode that is used for the treatment of the soft capsule preparation of vagina according to claim 1.
3. the soft capsule preparation that is used for the treatment of vagina according to claim 2 directly pushes vagina, reaches the purpose of treatment disease.
4. according to the described content weight percentage ratio that is used for the treatment of the soft capsule preparation of vagina of claim 1-4 item be: polyhexamethylene guanidine 0.1-1, chitin 1-5, Oleum Curcumae 15-25, soybean oil adds to 100.
5. according to the described prescription that is used for the treatment of the soft capsule preparation of vagina of claim 1-5 item be: gelatin 200-500 gram, purified water 100-400 gram, glycerol 50-300 gram, ethyl hydroxybenzoate 2-20 gram, propyl p-hydroxybenzoate 2-20 gram, 9% ethanol 20-80 gram, titanium dioxide 3-15 gram.
CN2009100722295A 2009-06-09 2009-06-09 Soft capsule for treating vagina Pending CN101919987A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2009100722295A CN101919987A (en) 2009-06-09 2009-06-09 Soft capsule for treating vagina

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2009100722295A CN101919987A (en) 2009-06-09 2009-06-09 Soft capsule for treating vagina

Publications (1)

Publication Number Publication Date
CN101919987A true CN101919987A (en) 2010-12-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN2009100722295A Pending CN101919987A (en) 2009-06-09 2009-06-09 Soft capsule for treating vagina

Country Status (1)

Country Link
CN (1) CN101919987A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103861035A (en) * 2014-03-11 2014-06-18 广州市洋林生物科技开发有限公司 External composition and external medicine/hygiene product for prevention and treatment of gynecological reproductive tract diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103861035A (en) * 2014-03-11 2014-06-18 广州市洋林生物科技开发有限公司 External composition and external medicine/hygiene product for prevention and treatment of gynecological reproductive tract diseases

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Application publication date: 20101222