CN101912458B - Medicament for treating protrasion of the lumbar intervertebral disci - Google Patents
Medicament for treating protrasion of the lumbar intervertebral disci Download PDFInfo
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- CN101912458B CN101912458B CN201010248731XA CN201010248731A CN101912458B CN 101912458 B CN101912458 B CN 101912458B CN 201010248731X A CN201010248731X A CN 201010248731XA CN 201010248731 A CN201010248731 A CN 201010248731A CN 101912458 B CN101912458 B CN 101912458B
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Abstract
The invention discloses a medicament for treating protrasion of the lumbar intervertebral disci, which is prepared from the following raw materials: 1.2 to 1.8 grams of Scorpion, 1.2 to 1.8 grams of centipede, 10 to 15 grams of pseudo-ginseng root, 10 to 15 grams of safflower, 10 to 15 grams of twotooth achyranthes root, 10 to 15 grams of rhizoma corydalis, 10 to 15 grams of szechwan chinaberry fruit, 10 to 15 grams of peach seed, 10 to 15 grams of suberect spatholobus stem, 8 to 10 grams of Szechuan lovage rhizome and 4 to 8 grams of liquoric root. The medicaments are put in a pot, added with a proper amount of water and soaked for 15 minutes; the medicaments are boiled for two times; the decoctions obtained at two times are mixed; the mixed decoction is taken twice a day and taken half hour later after meals in the morning and at evening; and 10 days is a treatment period. Clinic use shows that the medicament has a desirable treatment effect on protrasion of the lumbar intervertebral disci. Compared with other medicaments of the same kind, the medicament has the advantages of quick pain relief, high cure rate, reliable treatment effect, small toxic and side effect and the like. The treatment effectiveness of the medicament is up to 96.12 percent.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of prolapse of lumbar intervertebral disc, belong to technical field of Chinese medicines.
Background technology
Intervertebral disc prolapse is a kind of common clinical, frequently-occurring disease.After being intervertebral disc generation regression, because the effect of external force or the strain of accumulation property, fibrous ring is broken, and vertebral pulp is outstanding, stimulates or nerve that compressing is contiguous and position and limbs that it arranges occur and a series of symptoms occur.Go out that the damage of edema, fibrous ring and the posterior longitudinal ligament of vertebral pulp causes ooze out, aseptic inflammation such as adhesion makes nerve root be subjected to the stimulation of mechanical compressing and chemical, and lumbago and skelalgia, acid, heavy, bloated, numb, cool, unable even amyotrophy appear, the medicine of existing treatment prolapse of lumbar intervertebral disc is many can not eradicate primary disease.At present, hospital generally adopts 1, " ozone melts the nuclear art ", and behind the injecting ozone, X-ray shows that vertebral pulp obtains dissolving in intervertebral disc, and the dural sac form is recovered, and effectively removes the compressing to nerve.2, the vertebra way of escape resection of nucleus pulposus of windowing for a short time.3, operative treatment, postoperative bed 3 months even more of a specified duration, some may also need second operation.4, the complication of traditional treatment is also more, because the postoperative vertebral plate is all extractd, the stability of spinal column is affected, and the life of patient's postoperative is also had many restrictions.Not only patient will suffer on the huge health and spiritual misery, but also will bear huge financial burden.
Summary of the invention
The problem to be solved in the present invention is to provide a kind of medicine of treatment prolapse of lumbar intervertebral disc evident in efficacy.Treatment cycle is short, wound is little, misery less, expense is low, can recover the life before ill behind the therapy rehabilitation substantially fully.
For addressing the above problem, the present invention institute by the following technical solutions:
A kind of medicine for the treatment of prolapse of lumbar intervertebral disc, this medicine is made by following materials of weight proportions: Scorpio 1.2～1.8g; Scolopendra 1.2～1.8g; Radix Notoginseng 10～15g; Flos Carthami 10～15g; Radix Achyranthis Bidentatae 10～15g; Rhizoma Corydalis 10～15g; Fructus Toosendan 10～15g; Semen Persicae 10～15g; Caulis Spatholobi 10～15g; Rhizoma Chuanxiong 8～10g; Radix Glycyrrhizae 4～8g.
Below be further improvement of these options of the present invention:
Described medicine is made by following materials of weight proportions: Scorpio 1.2g; Scolopendra 1.2g; Radix Notoginseng 10g; Flos Carthami 10g; Radix Achyranthis Bidentatae 10g; Rhizoma Corydalis 10g; Fructus Toosendan 10g; Semen Persicae 10g; Caulis Spatholobi 10g; Rhizoma Chuanxiong 8g; Radix Glycyrrhizae 4g.
The another kind of improvement:
Described medicine is made by following materials of weight proportions: Scorpio 1.8g; Scolopendra 1.8g; Radix Notoginseng 15g; Flos Carthami 15g; Radix Achyranthis Bidentatae 15g; Rhizoma Corydalis 15g; Fructus Toosendan 15g; Semen Persicae 15g; Caulis Spatholobi 15g; Rhizoma Chuanxiong 10g; Radix Glycyrrhizae 8g.
The another kind of improvement:
Described medicine is made by following materials of weight proportions: Scorpio 1.5g; Scolopendra 1.5g; Radix Notoginseng 12g; Flos Carthami 12g; Radix Achyranthis Bidentatae 12g; Rhizoma Corydalis 12g; Fructus Toosendan 12g; Semen Persicae 12g; Caulis Spatholobi 12g; Rhizoma Chuanxiong 9g; Radix Glycyrrhizae 6g.
Said medicine put to add water in the pot an amount of, soaked 15 minutes, decoct twice, merge decocting liquid twice, divide sooner or later and take half an hour after meal for twice, 10 days is a course of treatment.
In the said medicine: Scorpio, Scolopendra, suffering, flat, be good at removing obstruction in the collateral to relieve pain, to the anemofrigid-damp arthralgia obstinate, muscle arteries and veins contracture person acts on rather good;
Radix Notoginseng, sweet, tepor, removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation is for controlling the good merchantable brand of all diseases of blood stasis.
Flos Carthami, suffering, temperature, blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia is for controlling the key medicine that the stasis of blood stagnates and swells and ache.
Semen Persicae, hardship, sweet, flat, blood circulation promoting and blood stasis dispelling is apt to let out stasis, and blood stasis dispelling power is strong, for treating the medicine commonly used of multiple blood-stasis syndrome.
Caulis Spatholobi, bitter, little sweet, temperature.Promoting the circulation of blood is enriched blood, and relaxing muscles and tendons and activating QI and blood in the collateral is the treatment rheumatic arthralgia, the medicine commonly used of numb limbs and tense tendons.
Rhizoma Chuanxiong, Xin Wen, blood-activating and qi-promoting, wind-expelling pain-stopping.For " the gas medicine in the blood " has sensible QI and blood effect, qi depression to blood stasis there is good effect, also kind dispelling the wind and dampness pathogens arthralgia pain.
Rhizoma Corydalis, hot, bitter, warm, blood-activating and qi-promoting pain relieving, its energy " stagnation of QI in the promoting the circulation of blood, the stasis in the gas is so can specially control the whole body all pains up and down ".No matter which kind of is demonstrate,proved bitterly, but all compatibility is used.
Fructus Toosendan, bitter cold, promoting the circulation of QI to relieve pain.
Radix Achyranthis Bidentatae, bitter, sweet, sour, flat, blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, it is descending to draw blood (medicine), can be used for lumbago, the soreness of waist and knee joint of caused by liver and kidney deficiency.
Radix Glycyrrhizae, relieving spasm to stop pain, the mediation property of medicine of holding concurrently.
Scorpio, Scolopendra two medicines share and are monarch in the said medicine; The power that Radix Notoginseng, Flos Carthami, Semen Persicae three medicines share promoting blood circulation, removing blood stasis and relieving pain then is very strong, is ministerial drug altogether, and Rhizoma Chuanxiong, Rhizoma Corydalis, Fructus Toosendan three medicines are adjuvant drug altogether, and Radix Achyranthis Bidentatae, Radix Glycyrrhizae two medicines are for making.
Scorpion body and scorpion tail preparation all have obvious analgesic activity to animal body pain or Encelialgia in the said medicine; Scolopendra can promote the metabolism of human body, and during with Scolopendra powder orally taken for curing bone tuberculosis, it damages tissue part, newborn granulation hyperplasia after two weeks.Radix Notoginseng, Flos Carthami, Rhizoma Corydalis, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Radix Glycyrrhizae have analgesia, antiinflammatory, the anti-ageing effect of waiting for a long time.The excited intestinal tube smooth muscle of Fructus Toosendan energy increases its tension force and contractility, and antiinflammatory action is still arranged.The Semen Persicae extracting solution can increase the blood flow of tremulous pulse, reduces vascular resistance, improves hemodynamic situation, analgesia, antiinflammatory, antimicrobial effect are arranged, Caulis Spatholobi can increase the laboratory animal femoral artery blood flow, reduces vascular resistance, and platelet aggregation is had obvious inhibitory action; Can reduce the animal cholesterol, obviously resist atherosclerotic lesion, tangible antiinflammatory action is arranged.
The present invention treats intervertebral disc prolapse through clinic trial, has obtained satisfactory effect, similar medicine with other relatively, it is fast that we have the pain of alleviation, the cure rate height, advantage such as curative effect is reliable, and toxic and side effects is little, the treatment effective percentage reaches 96.12%.
The invention will be further described below in conjunction with embodiment:
The specific embodiment
Embodiment from year January in January, 2007 to 2009, successively carries out clinical treatment to 248 routine prolapse of lumbar intervertebral disc patients, wherein male 159 examples, women 89 examples; 20 years old～65 years old age; The course of disease 4 months～5 years; Symptom is that flank pain, acid are expanded, the back is tetanic before going to a doctor, and companion's numbness of lower limbs can't be movable.
Be divided into treatment I, II, III group and matched group at random, every group 62 routine patient, treatment I, II, III group are taken the present invention's treatment and are made comparisons with the matched group that adopts conventional therapy.
Treatment I group adopts following therapeutic scheme: described medicine is made by following materials of weight proportions: Scorpio 1.2g; Scolopendra 1.2g; Radix Notoginseng 10g; Flos Carthami 10g; Radix Achyranthis Bidentatae 10g; Rhizoma Corydalis 10g; Fructus Toosendan 10g; Semen Persicae 10g; Caulis Spatholobi 10g; Rhizoma Chuanxiong 8g; Radix Glycyrrhizae 4g.
Said medicine put in the cold water that adds 2L in the pot and soaked 15 minutes, boil with moderate heat then, the back continuation of boiling uses slow fire boiling after 15～25 minutes, leach the about 200mL of medicinal liquid, and then in the medicine pot, add the cold water of 1.5L, boil the back with moderate heat and continue with slow fire boiling after 15～25 minutes, leach the about 150mL of medicinal liquid, with the medicinal liquid mix homogeneously that leaches for twice, potion divided sooner or later and took half an hour after meal for twice every day.
Treatment II group adopts following therapeutic scheme: described medicine is made by following materials of weight proportions: Scorpio 1.8g; Scolopendra 1.8g; Radix Notoginseng 15g; Flos Carthami 15g; Radix Achyranthis Bidentatae 15g; Rhizoma Corydalis 15g; Fructus Toosendan 15g; Semen Persicae 15g; Caulis Spatholobi 15g; Rhizoma Chuanxiong 10g; Radix Glycyrrhizae 8g.
Said medicine put in the cold water that adds 3L in the pot and soaked 20 minutes, boil with moderate heat then, the back continuation of boiling uses slow fire boiling after 15～25 minutes, leach the about 300mL of medicinal liquid, and then in the medicine pot, add the cold water of 2.5L, boil the back with moderate heat and continue with slow fire boiling after 15～25 minutes, leach the about 250mL of medicinal liquid, with the medicinal liquid mix homogeneously that leaches for twice, potion divided sooner or later and took half an hour after meal for twice every day.
Treatment III group adopts following therapeutic scheme: described medicine is made by following materials of weight proportions: described medicine is made by following materials of weight proportions: medicine is taken by weighing according to following weight: Scorpio 1.5g; Scolopendra 1.5g; Radix Notoginseng 12g; Flos Carthami 12g; Radix Achyranthis Bidentatae 12g; Rhizoma Corydalis 12g; Fructus Toosendan 12g; Semen Persicae 12g; Caulis Spatholobi 12g; Rhizoma Chuanxiong 9g; Radix Glycyrrhizae 6g.
Said medicine put in the cold water that adds 2.5L in the pot and soaked 18 minutes, boil with moderate heat then, the back continuation of boiling uses slow fire boiling after 15～25 minutes, leach the about 250mL of medicinal liquid, and then in the medicine pot, add the cold water of 2L, boil the back with moderate heat and continue with slow fire boiling after 15～25 minutes, leach the about 200mL of medicinal liquid, with the medicinal liquid mix homogeneously that leaches for twice, potion divided sooner or later and took half an hour after meal for twice every day.
Matched group adopts traditional nonoperative therapeutic scheme.
The patient takes Chinese medicine of the present invention treatment time of a course of treatment, follows up a case by regular visits to every day once, comprises that symptom, sign improve situation, untoward reaction, and criterion of therapeutical effect: clinical cure: symptom, positive sign disappear, can operate as normal and work, there is not recurrence in 1 year; Produce effects: subjective symptoms alleviates, and positive sign is improved substantially, and is more stable, can be engaged in housework and light physical labor; Effectively: symptom and sign is alleviated before the treatment, but still has pain and discomfort, only can take care of oneself; Invalid: symptom and sign be the preceding no change of treatment.
Clinical cure 158 examples account for 61.2%, and produce effects 51 examples account for 19.8%, and effective 39 examples account for 15.4%, and invalid 10 examples account for 3.88%, total effective rate 96.12%.
Draw through following up a case by regular visits to, after the treatment of a course of treatment, treatment I organizes 45 routine clinical cures among the 62 routine patients, 11 routine produce effects, and 4 examples are effective, and 2 examples are invalid.
Treatment II organizes 39 routine clinical cures among the 62 routine patients, 14 routine produce effects, and 5 examples are effective, and 4 examples are invalid.
Treatment III organizes 47 routine clinical cures among the 62 routine patients, 8 routine produce effects, and 6 examples are effective, and 1 example is invalid.
Among the matched group 62 routine patients 25 routine clinical cures are arranged, 16 routine produce effects, 9 examples are effective, and 12 examples are invalid.
Therefore the therapeutic effect of treatment group obviously is better than matched group, and in three groups of treatment group, treatment III group is the optimum treatment scheme for therapeutic scheme.
All are cured the patient and treat through the observation in 1 year again, none recurrence of the case of clinical cure, the case symptom of produce effects, positive sign disappear, and energy operate as normal and work do not have recurrence in 1 year, reach criterion of cure, effectively the case subjective symptoms alleviates, and positive sign is improved substantially, and is more stable, can be engaged in housework and light physical labor, the treatment effective percentage reaches 96.12%.
Model case 1, Cai, man, 45 years old, XX people from village, Gaomi City, Shandong Province.Hypomere bilateral pain in the waist, acid are expanded, the back is tetanic, limitation of activity.Find that through CT examination its L4～5 are outstanding, take the treatment in 16 days of this medicine after, pain obviously alleviates, continue to take 20 days after, lumbago disappears, activity freely.
Model case 2, Lee so-and-so, man, 39 years old, XX people from village, Gaomi City, Shandong Province.Flank pain, companion's left lower extremity numbness, movable difficulty.Find that through CT examination its L5～S1 is outstanding, take the treatment in 13 days of this medicine after, pain relief continued to take this medicine after 16 days, lumbago disappears, can operate as normal and work.
Model case 3, Wang, woman, 47 years old, people from town of Gaomi City, Shandong Province man.Flank pain, back are tetanic, can't be movable, and the both legs numbness.Find that through CT examination its L3～4 and L4～5 are outstanding, take the treatment in 25 days of this medicine after, pain obviously alleviates, continue to take 20 days after, lumbago disappears, activity freely.
Claims (4)
1. medicine for the treatment of prolapse of lumbar intervertebral disc, it is characterized in that: this medicine is made by following materials of weight proportions: Scorpio 1.2～1.8g; Scolopendra 1.2～1.8g; Radix Notoginseng 10～15g; Flos Carthami 10～15g; Radix Achyranthis Bidentatae 10～15g; Rhizoma Corydalis 10～15g; Fructus Toosendan 10～15g; Semen Persicae 10～15g; Caulis Spatholobi 10～15g; Rhizoma Chuanxiong 8～10g; Radix Glycyrrhizae 4～8g.
2. a kind of medicine for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that: described medicine is made by following materials of weight proportions: Scorpio 1.2g; Scolopendra 1.2g; Radix Notoginseng 10g; Flos Carthami 10g; Radix Achyranthis Bidentatae 10g; Rhizoma Corydalis 10g; Fructus Toosendan 10g; Semen Persicae 10g; Caulis Spatholobi 10g; Rhizoma Chuanxiong 8g; Radix Glycyrrhizae 4g.
3. a kind of medicine for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that: described medicine is made by following materials of weight proportions: Scorpio 1.8g; Scolopendra 1.8g; Radix Notoginseng 15g; Flos Carthami 15g; Radix Achyranthis Bidentatae 15g; Rhizoma Corydalis 15g; Fructus Toosendan 15g; Semen Persicae 15g; Caulis Spatholobi 15g; Rhizoma Chuanxiong 10g; Radix Glycyrrhizae 8g.
4. a kind of medicine for the treatment of prolapse of lumbar intervertebral disc according to claim 1, it is characterized in that: described medicine is made by following materials of weight proportions: Scorpio 1.5g; Scolopendra 1.5g; Radix Notoginseng 12g; Flos Carthami 12g; Radix Achyranthis Bidentatae 12g; Rhizoma Corydalis 12g; Fructus Toosendan 12g; Semen Persicae 12g; Caulis Spatholobi 12g; Rhizoma Chuanxiong 9g; Radix Glycyrrhizae 6g.
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| CN201010248731XA CN101912458B (en) | 2010-08-10 | 2010-08-10 | Medicament for treating protrasion of the lumbar intervertebral disci |
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| CN201010248731XA CN101912458B (en) | 2010-08-10 | 2010-08-10 | Medicament for treating protrasion of the lumbar intervertebral disci |
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| CN101912458A CN101912458A (en) | 2010-12-15 |
| CN101912458B true CN101912458B (en) | 2011-09-07 |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610761B (en) * | 2013-11-28 | 2016-09-07 | 吴正龙 | A kind of medicament treating spur |
| CN105106360A (en) * | 2015-08-05 | 2015-12-02 | 李武 | Traditional Chinese medicine pharmaceutical for treating lumbar intervertebral disc protrusion and preparation method thereof |
| CN111437361A (en) * | 2020-05-06 | 2020-07-24 | 郜占稳 | Plaster for treating lumbar intervertebral disc protrusion and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1491699A (en) * | 2003-09-03 | 2004-04-28 | 邢吉民 | Medicinal formula for treating hyperosteogeny and prolapse of lumbar intervertebral disc |
| CN1803187A (en) * | 2005-08-11 | 2006-07-19 | 葛小平 | Chinese herbal medicine for treating lumbar intervertebral disk protrusion and hyperosteogeny |
| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Chinese-medicinal composition for treating neck, shoulder, waist and legs diseases and its making method |
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2010
- 2010-08-10 CN CN201010248731XA patent/CN101912458B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1491699A (en) * | 2003-09-03 | 2004-04-28 | 邢吉民 | Medicinal formula for treating hyperosteogeny and prolapse of lumbar intervertebral disc |
| CN1895642A (en) * | 2005-07-12 | 2007-01-17 | 侯保君 | Chinese-medicinal composition for treating neck, shoulder, waist and legs diseases and its making method |
| CN1803187A (en) * | 2005-08-11 | 2006-07-19 | 葛小平 | Chinese herbal medicine for treating lumbar intervertebral disk protrusion and hyperosteogeny |
Non-Patent Citations (2)
| Title |
|---|
| 农勇安等.中药治疗腰椎间盘突出症的近况及评价.《颈腰痛杂志》.2004,第25卷(第04期), * |
| 郑晓红.中医药治疗腰椎间盘突出症的研究近况.《上海中医药杂志》.2001,(第07期), * |
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