CN101910171A - 可用作糖皮质激素受体AP-1和/或者NF-κB活性调节剂的非甾类化合物及其用途 - Google Patents

可用作糖皮质激素受体AP-1和/或者NF-κB活性调节剂的非甾类化合物及其用途 Download PDF

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Publication number
CN101910171A
CN101910171A CN2008801237144A CN200880123714A CN101910171A CN 101910171 A CN101910171 A CN 101910171A CN 2008801237144 A CN2008801237144 A CN 2008801237144A CN 200880123714 A CN200880123714 A CN 200880123714A CN 101910171 A CN101910171 A CN 101910171A
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alkyl
substituted
hydrogen
inhibitor
aryl
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Chinese (zh)
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T·G·M·达
肖海云
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Bristol Myers Squibb Co
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Bristol Myers Squibb Co
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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CN2008801237144A 2007-11-01 2008-10-30 可用作糖皮质激素受体AP-1和/或者NF-κB活性调节剂的非甾类化合物及其用途 Pending CN101910171A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US98451507P 2007-11-01 2007-11-01
US60/984,515 2007-11-01
PCT/US2008/081702 WO2009058944A2 (en) 2007-11-01 2008-10-30 Nonsteroidal compounds useful as modulators of glucocorticoid receptor ap-1 and /or nf- kappa b activity and use thereof

Publications (1)

Publication Number Publication Date
CN101910171A true CN101910171A (zh) 2010-12-08

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CN2008801237144A Pending CN101910171A (zh) 2007-11-01 2008-10-30 可用作糖皮质激素受体AP-1和/或者NF-κB活性调节剂的非甾类化合物及其用途

Country Status (6)

Country Link
US (1) US8309730B2 (https=)
EP (1) EP2209780B1 (https=)
JP (1) JP2011503081A (https=)
CN (1) CN101910171A (https=)
ES (1) ES2448839T3 (https=)
WO (1) WO2009058944A2 (https=)

Cited By (1)

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CN109761976A (zh) * 2013-11-25 2019-05-17 科赛普特治疗公司 八氢稠合的氮杂萘烷糖皮质激素受体调节剂

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CN108864086A (zh) * 2018-07-20 2018-11-23 新乡学院 一种四氢异喹啉并咪唑骨架化合物及其制备方法
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CN109761976A (zh) * 2013-11-25 2019-05-17 科赛普特治疗公司 八氢稠合的氮杂萘烷糖皮质激素受体调节剂
CN109761976B (zh) * 2013-11-25 2021-11-23 科赛普特治疗公司 八氢稠合的氮杂萘烷糖皮质激素受体调节剂

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WO2009058944A3 (en) 2009-07-02
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US20110263494A1 (en) 2011-10-27
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