CN101896197B - 来自艰难梭菌的新型多糖免疫原 - Google Patents
来自艰难梭菌的新型多糖免疫原 Download PDFInfo
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- CN101896197B CN101896197B CN2008801155182A CN200880115518A CN101896197B CN 101896197 B CN101896197 B CN 101896197B CN 2008801155182 A CN2008801155182 A CN 2008801155182A CN 200880115518 A CN200880115518 A CN 200880115518A CN 101896197 B CN101896197 B CN 101896197B
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- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
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- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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| US60/971,411 | 2007-09-11 | ||
| PCT/CA2008/001593 WO2009033268A1 (en) | 2007-09-11 | 2008-09-11 | Novel polysaccharide immunogens from clostridium difficile |
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| EP2655389A2 (en) * | 2010-12-24 | 2013-10-30 | Novartis AG | Compounds |
| CA2828374A1 (en) | 2011-03-08 | 2012-09-13 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Oligosaccharides and oligosaccharide-protein conjugates derived from clostridium difficile polysaccharide ps-ii, methods of synthesis and uses thereof, in particular as a vaccine |
| EP2554549A1 (en) | 2011-08-02 | 2013-02-06 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Oligosaccharides and oligosaccharides-protein conjugates derived from clostridium difficile polysaccharide PS-I, methods of synthesis and uses thereof, in particular as vaccines and diagnostic tools |
| US9815889B2 (en) | 2011-08-02 | 2017-11-14 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Antibodies for prevention and treatment of diseases caused by clostridium difficile |
| WO2013071409A1 (en) | 2011-11-18 | 2013-05-23 | National Research Council Of Canada (Nrc) | Clostridium difficile lipoteichoic acid and uses thereof |
| EP2872535A1 (en) | 2012-07-16 | 2015-05-20 | Pfizer Inc. | Saccharides and uses thereof |
| ES2672045T3 (es) * | 2014-07-25 | 2018-06-12 | Biosynth S.R.L. | Vacunas de productos glicoconjugados que comprenden unidades básicas de una construcción molecular que expresa múltiples epítopos incorporados para la formulación de una vacuna de amplio espectro contra infecciones debidas a bacterias enteropatógenas |
| CA3084847A1 (en) * | 2017-12-19 | 2019-06-27 | The Governors Of The University Of Alberta | Clostridium perfringens surface glycans and uses thereof |
| US10933126B2 (en) | 2018-05-03 | 2021-03-02 | The Board Of Regents Of The University Of Oklahoma | Clostridium difficile immunogenic compositions and methods of use |
| CN113329766A (zh) * | 2018-11-16 | 2021-08-31 | 马特里瓦克斯公司 | 艰难梭菌多组分疫苗 |
| US12187756B2 (en) | 2018-11-22 | 2025-01-07 | Idorsia Pharmaceuticals Ltd | Stable vaccine against Clostridium difficile |
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| CN1518456A (zh) * | 2001-06-20 | 2004-08-04 | 溶解和结合荚膜多糖的疫苗 |
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| US4673574A (en) | 1981-08-31 | 1987-06-16 | Anderson Porter W | Immunogenic conjugates |
| CA1331443C (en) | 1987-05-29 | 1994-08-16 | Charlotte A. Kensil | Saponin adjuvant |
| US5283185A (en) | 1991-08-28 | 1994-02-01 | University Of Tennessee Research Corporation | Method for delivering nucleic acids into cells |
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| CN1518456A (zh) * | 2001-06-20 | 2004-08-04 | 溶解和结合荚膜多糖的疫苗 |
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2674169B1 (en) | 2015-01-28 |
| US20100330125A1 (en) | 2010-12-30 |
| ES2534671T3 (es) | 2015-04-27 |
| CA2941174A1 (en) | 2009-03-19 |
| CN101896197A (zh) | 2010-11-24 |
| EP2674169A1 (en) | 2013-12-18 |
| EP2195018B1 (en) | 2014-11-12 |
| ES2528648T3 (es) | 2015-02-11 |
| EP2195018A1 (en) | 2010-06-16 |
| EP2195018A4 (en) | 2011-01-12 |
| CA2698157C (en) | 2016-10-11 |
| CA2698157A1 (en) | 2009-03-19 |
| CA2941174C (en) | 2018-05-08 |
| WO2009033268A1 (en) | 2009-03-19 |
| AU2008299536A1 (en) | 2009-03-19 |
| JP2010539256A (ja) | 2010-12-16 |
| AU2008299536B2 (en) | 2014-06-12 |
| US8597663B2 (en) | 2013-12-03 |
| JP5501969B2 (ja) | 2014-05-28 |
| NZ583750A (en) | 2012-05-25 |
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