CN101890116A - Anthocyanin health-care eye drops and preparation method thereof - Google Patents
Anthocyanin health-care eye drops and preparation method thereof Download PDFInfo
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- CN101890116A CN101890116A CN2010101092445A CN201010109244A CN101890116A CN 101890116 A CN101890116 A CN 101890116A CN 2010101092445 A CN2010101092445 A CN 2010101092445A CN 201010109244 A CN201010109244 A CN 201010109244A CN 101890116 A CN101890116 A CN 101890116A
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Abstract
The invention relates to health-care eye drops which are prepared from anthocyanin extracted from blueberries, grape seeds and sea-buckthorn and have prevention and treatment and health-care effects on eye diseases and a preparation method thereof. The preparation method comprises the following steps of: adding an appropriate amount of anthocyanin into the eye drops by using fresh double distilled water; adjusting the pH value of the eye drops to be between 6.0 and 7.2; filling the eye drops in an eye drop bottle; and sealing the eye drop bottle to obtain an eye drop product. The eye drops of the invention have certain effects of protecting eyesight, preventing eye damage, and treating nyctalopia, nearsightedness, glaucoma, retinal defect caused by diabetes, cataract and macular degeneration, improve capillary circulation of eyeballs, clear toxins in eyes, provide nutrients needed by the eyes, prevent and relieve eyestrain, discomfort, dryness and eye acid bilge caused by long-term use of computer and reading, contribute to recovering eyesight of weak-sight patients and treat glaucoma, conjunctival congestion, conjunctivitis and chronic xerosis of conjunctiva.
Description
Technical field
The present invention relates to a kind of eyes of protecting and also can prevent and treat collyrium of some ocular disease and preparation method thereof.
Background technology
Eyes are human extremely important sensory organ.In order to protect eyes and to safeguard vision, come people to invent many methods for a long time in order to prevent, treat ocular disease, developed many medicines.Particularly developed again in recent years and manyly prevented that vision is tired, the various collyrium that health care is arranged of blurred vision, raising vision.Especially now every day for a long time in front of the computer people of work particularly need this collyrium that not only can prevent but also can keep healthy.Also had several in recent years to the collyrium listing of ocular disease by prevention and health-care effect.
1, Chinese patent application CN93111305.9.The present invention is a kind of main treatment xerophthalmia, also can treat the eye drop of various oculopathy such as trachoma, conjunctivitis, corneal ulcer and eyeball inflammation.The prescription and the consumption of eye drop of the present invention are: in the 100ml eye drop,, wherein chloromycetin 0.25 gram, boric acid 1.4～1.9 grams, Borax 0.03～0.3 restrain, hyaluronic acid sodium 0.1～0.5 gram, and phenylmercuric acetate 0.002～0.005 gram, all the other are distilled water.Eye drop treatment xerophthalmia effect of the present invention is remarkable, and various oculopathy such as treatment trachoma, conjunctivitis, corneal ulcer, eyeball inflammation are all better than chloromycetin eyedrops and various eye ointment curative effect.
2, Chinese patent application CN93111435.X.What the present invention proposed is a kind of pearl eye drops, belong to field of pharmaceutical technology, its composition proportion amount: Margarita hydrolyzed solution 0.88-0.97, red trematodiasis hydrolyzed solution 0.005-0.033, borneol 0.002-0.018, Herba Menthae 0.005-0.033, boric acid 0.005-0.015, sodium chloride 0.003-0.009, nipalgin 0.0001-0.001, polyethylene pyrrolinone (K30) 0.001-0.01.Adopt Hirudo, Margarita water medium liquid, the Herba Menthae extracting solution mixes, and regulates pH value and technological processes such as osmotic pressure, filtration.Through using senile cataract, improving vision tangible curative effect is all arranged.Using in 15 minutes and reduce intraocular pressure, is ideal collyrium.
Above-mentioned two kinds of collyrium are more representational and rank forefront several product of market sales volume row, it is main that but main indication remains treatment, thus research invention a kind of based on the prevention ocular disease, improve the local nutrition of crystal, the collyrium of alleviating eye muscle fatigue has crucial practical significance.
Summary of the invention
What the present invention adopted is by made a kind of collyrium that ocular disease is had treatment, prevention and health protection effect of the anthocyanidin that is extracted in blue berry, Semen Vitis viniferae, the Fructus Hippophae and preparation method thereof.
(Procyanidins is called for short PC, English former name to anthocyanidin
Proanthocyanidins, Pycnogenol is the natural polyphenol chemical compound that an extensive class that exists belongs to the bisflavone derivant in the plant Leucoan-Thocyanidin), has the people that it is classified as bioflavonoids, also has the people that it is classified as condensed tannin.Anthocyanidin before videophile and computer fan are sitting in fluorescent screen for a long time, makes eyes be subjected to very strong radiation damage as the antioxidant of pure natural, and this damage mainly is exactly radical pair eye lens and amphiblestroid damage.And the effect of anthocyanidin removing interior free yl is very tangible, has prevented the oxidation of radical pair crystallin matter, thereby has prevented cataractous generation.In fact the health of eyes also depends on the integrity of those atomic thin blood vessels of eye on exhausted big degree, and these blood vessels provide blood for eyes.Anthocyanidin can significantly improve VAR, reduces vascular permeability, thereby has suppressed the seepage of material in the blood, the generation of prevention disease of eye.In fact as far back as in World War II, a kind of beverage that contains anthocyanidin is just taken by RAF, because anthocyanidin can help to remove deleterious chemical substance and free radical in the retina, improve the microcirculation of circumference of eyes, strengthen photoactive substance---the generation of rhodopsin of eyes, enlarge the adusk field range of eyes, improve the acuity of vision.Anthocyanidin can also help vision to recover from high light rapidly, and keeps the visus acris in night.The researcher of Japan finds that also edible blue berry and anthocyanidin can help the amblyopia patient to recover vision.
So the present invention be exactly many be the eye drop that primary raw material is made on to the basis of anthocyanidin functional study with anthocyanidin, and finished zoopery and obtained result preferably, make the eye drop that uses for the people according to implementer's method of patent of the present invention then.
The present invention realizes by following technology:
Collyrium is formed in 1000ml, anthocyanidin 250mg wherein, and osmotic pressure regulator 35g, pH value regulator 200 microlitres, all the other are distilled water.
Anthocyanidin selects for use the purity extracted in the blue berry at 98% dried powder, and osmotic pressure regulator is selected sodium chloride for use, and the pH value regulator is a sodium hydroxide.
The specific embodiment 1,
With anthocyanidin 250mg, sodium chloride 35g adds in an amount of distilled water fully dissolving, again with 200 microlitre sodium hydroxide regulate pH value to 7.0. behind abundant mixing adding distil water to 1000ml.With 0.2 micron microporous filter membrane degerming, seal after the packing and promptly get collyrium of the present invention.
Claims (5)
1. one kind contains the collyrium that the anthocyanidin that extracts is prepared from from blue berry, Semen Vitis viniferae, Fructus Hippophae and other fruit.It is characterized in that anthocyanidin is main effective active composition.
2. collyrium as claimed in claim 1 is characterized in that to contain anthocyanidin 250mg in the 1000ml collyrium.Osmotic pressure regulator 35g, ph value adjusting control agent 250 microlitres, all the other are distilled water.
3. as the collyrium under the right 2, its effective ingredient is that the anthocyanidin that extracts from blue berry is prepared from.
4. as the collyrium under the right 2, what it is characterized by that the straight adjusting control agent of ph adopted is sodium hydroxide.
5. as the collyrium under the right 2, what it is characterized by that described penetrating agent selects for use is sodium chloride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101092445A CN101890116A (en) | 2010-02-11 | 2010-02-11 | Anthocyanin health-care eye drops and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010101092445A CN101890116A (en) | 2010-02-11 | 2010-02-11 | Anthocyanin health-care eye drops and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
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| CN101890116A true CN101890116A (en) | 2010-11-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN2010101092445A Pending CN101890116A (en) | 2010-02-11 | 2010-02-11 | Anthocyanin health-care eye drops and preparation method thereof |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102432581A (en) * | 2012-02-01 | 2012-05-02 | 唐忠海 | Method for extracting cyanidin from sea buckthorn waste residue |
| CN106963770A (en) * | 2017-03-31 | 2017-07-21 | 牡丹江医学院 | It is a kind of to be used to prevent and treat eye drops of drying property angle/conjunctivitis and its production and use |
| CN111195265A (en) * | 2018-11-16 | 2020-05-26 | 周瑜帅 | Cleaning type eye drop capable of preventing dryness |
| CN111821314A (en) * | 2020-03-25 | 2020-10-27 | 巫远程 | Eye drops for treating myopia and cataract and its preparing process |
| CN112336761A (en) * | 2020-12-04 | 2021-02-09 | 广州陈锦济生物科技有限公司 | Anti-radiation eye moistening liquid and preparation method thereof |
| JPWO2019168185A1 (en) * | 2018-03-02 | 2021-02-18 | ロート製薬株式会社 | Food composition for prevention and / or risk reduction of posterior ocular abnormalities |
| CN112791113A (en) * | 2020-12-29 | 2021-05-14 | 济南瑞隆安生物技术有限公司 | Blueberry and lutein eye drops for relieving eye fatigue and preparation method thereof |
| CN113876706A (en) * | 2021-09-27 | 2022-01-04 | 李青 | Anthocyanin suspension eye drops and preparation method thereof |
-
2010
- 2010-02-11 CN CN2010101092445A patent/CN101890116A/en active Pending
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102432581A (en) * | 2012-02-01 | 2012-05-02 | 唐忠海 | Method for extracting cyanidin from sea buckthorn waste residue |
| CN106963770A (en) * | 2017-03-31 | 2017-07-21 | 牡丹江医学院 | It is a kind of to be used to prevent and treat eye drops of drying property angle/conjunctivitis and its production and use |
| CN106963770B (en) * | 2017-03-31 | 2020-03-27 | 牡丹江医学院 | Eye drops for preventing and treating keratoconjunctivitis sicca and preparation method and application thereof |
| JPWO2019168185A1 (en) * | 2018-03-02 | 2021-02-18 | ロート製薬株式会社 | Food composition for prevention and / or risk reduction of posterior ocular abnormalities |
| JP7304585B2 (en) | 2018-03-02 | 2023-07-07 | ロート製薬株式会社 | Food composition for prevention and/or risk reduction of posterior segment abnormality |
| CN111195265A (en) * | 2018-11-16 | 2020-05-26 | 周瑜帅 | Cleaning type eye drop capable of preventing dryness |
| CN111821314A (en) * | 2020-03-25 | 2020-10-27 | 巫远程 | Eye drops for treating myopia and cataract and its preparing process |
| CN112336761A (en) * | 2020-12-04 | 2021-02-09 | 广州陈锦济生物科技有限公司 | Anti-radiation eye moistening liquid and preparation method thereof |
| CN112791113A (en) * | 2020-12-29 | 2021-05-14 | 济南瑞隆安生物技术有限公司 | Blueberry and lutein eye drops for relieving eye fatigue and preparation method thereof |
| CN113876706A (en) * | 2021-09-27 | 2022-01-04 | 李青 | Anthocyanin suspension eye drops and preparation method thereof |
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| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20101124 |