CN111195265A - Cleaning type eye drop capable of preventing dryness - Google Patents
Cleaning type eye drop capable of preventing dryness Download PDFInfo
- Publication number
- CN111195265A CN111195265A CN201811368994.7A CN201811368994A CN111195265A CN 111195265 A CN111195265 A CN 111195265A CN 201811368994 A CN201811368994 A CN 201811368994A CN 111195265 A CN111195265 A CN 111195265A
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- CN
- China
- Prior art keywords
- parts
- eye drop
- chloramphenicol
- preventing dryness
- type eye
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 239000003889 eye drop Substances 0.000 title claims abstract description 33
- 238000004140 cleaning Methods 0.000 title claims abstract description 16
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims abstract description 26
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims abstract description 16
- 235000003704 aspartic acid Nutrition 0.000 claims abstract description 16
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims abstract description 16
- WIIZWVCIJKGZOK-RKDXNWHRSA-N chloramphenicol Chemical compound ClC(Cl)C(=O)N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1 WIIZWVCIJKGZOK-RKDXNWHRSA-N 0.000 claims abstract description 16
- 229960005091 chloramphenicol Drugs 0.000 claims abstract description 16
- 239000007788 liquid Substances 0.000 claims abstract description 16
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 13
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910021538 borax Inorganic materials 0.000 claims abstract description 13
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000004327 boric acid Substances 0.000 claims abstract description 13
- 229940116229 borneol Drugs 0.000 claims abstract description 13
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 claims abstract description 13
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 claims abstract description 13
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 13
- 239000004328 sodium tetraborate Substances 0.000 claims abstract description 13
- 235000010339 sodium tetraborate Nutrition 0.000 claims abstract description 13
- 229960003080 taurine Drugs 0.000 claims abstract description 13
- 229940011671 vitamin b6 Drugs 0.000 claims abstract description 13
- 229960005261 aspartic acid Drugs 0.000 claims abstract description 7
- 238000000034 method Methods 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims description 3
- 206010013774 Dry eye Diseases 0.000 abstract description 3
- 210000003608 fece Anatomy 0.000 abstract description 3
- 239000011521 glass Substances 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 229920000136 polysorbate Polymers 0.000 abstract description 3
- 230000009286 beneficial effect Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/22—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a cleaning type eye drop capable of preventing dryness, which comprises pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid, and the cleaning type eye drop capable of preventing dryness is capable of relieving the dryness of eyes by adding tween and aspartic acid into the eye drop; by adding chloramphenicol into the eye drop, the production of eye droppings of the glasses can be reduced, and the cleaning function is improved.
Description
Technical Field
The invention belongs to an eye drop.
Background
The eye use degree in the present society is great, not only student's study, still white collar uses the computer on duty, and long-time high strength uses eyes, can lead to the eye dry and astringent, influences people's study, and the eye drop that uses now only alleviates dry and astringent.
Disclosure of Invention
In order to solve the problems, the invention provides a cleaning type eye drop capable of preventing dryness, wherein the eye drop can relieve dryness of eyes by adding tween and aspartic acid into the eye drop; by adding chloramphenicol into the eye drop, the production of eye droppings of the glasses can be reduced, and the cleaning function is improved.
In order to achieve the purpose, the invention adopts the technical scheme that: a clean type eye drop capable of preventing dryness is characterized in that: comprises pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid.
Wherein, the components in the preparation are as follows: 45-55 parts of boric acid, 15-20 parts of borax and 1-2 parts of borneol; 5-6 parts of chloramphenicol, 4-5 parts of vitamin b6, 3-5 parts of aspartic acid, 8-12 parts of taurine and 5-6 parts of pearl liquid.
Wherein the cleaning type eye drop capable of preventing dryness is liquid.
Wherein the cleaning type eye drop capable of preventing dryness requires dripping the eye drop into eyes when in use.
The invention has the beneficial effects that: the invention relates to a cleaning type eye drop capable of preventing dryness, wherein Tween and aspartic acid are added into the eye drop, so that the dryness of eyes can be relieved; by adding chloramphenicol into the eye drop, the production of eye droppings of the glasses can be reduced, and the cleaning function is improved.
A method for preparing a clean eye drop capable of preventing dryness,
step 1, preparing pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid;
step 2, preparing according to 45-55 parts of boric acid, 15-20 parts of borax and 1-2 parts of borneol; 5-6 parts of chloramphenicol, 4-5 parts of vitamin b6, 3-5 parts of aspartic acid, 8-12 parts of taurine and 5-6 parts of pearl liquid.
Drawings
Fig. 1 is a flow chart of a method for preparing a cleaning type eye drop capable of preventing dryness.
Detailed Description
In order to achieve the purpose, the invention adopts the technical scheme that: a clean type eye drop capable of preventing dryness is characterized in that: comprises pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid.
Wherein, the components in the preparation are as follows: 45-55 parts of boric acid, 15-20 parts of borax and 1-2 parts of borneol; 5-6 parts of chloramphenicol, 4-5 parts of vitamin b6, 3-5 parts of aspartic acid, 8-12 parts of taurine and 5-6 parts of pearl liquid.
Wherein the cleaning type eye drop capable of preventing dryness is liquid.
Wherein the cleaning type eye drop capable of preventing dryness requires dripping the eye drop into eyes when in use.
A method for preparing a clean eye drop capable of preventing dryness,
step 1, preparing pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid;
step 2, preparing according to 45-55 parts of boric acid, 15-20 parts of borax and 1-2 parts of borneol; 5-6 parts of chloramphenicol, 4-5 parts of vitamin b6, 3-5 parts of aspartic acid, 8-12 parts of taurine and 5-6 parts of pearl liquid.
Claims (4)
1. The utility model provides a can prevent clean type eye drop of drier, its characterized in that: comprises pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid, and the preparation comprises the following components: 45-55 parts of boric acid, 15-20 parts of borax and 1-2 parts of borneol; 5-6 parts of chloramphenicol, 4-5 parts of vitamin b6, 3-5 parts of aspartic acid, 8-12 parts of taurine and 5-6 parts of pearl liquid.
2. A cleansing type eye drop capable of preventing dryness according to claim 1, wherein: the cleaning type eye drop capable of preventing dryness is liquid.
3. A cleansing type eye drop capable of preventing dryness according to claim 1, wherein: the cleaning type eye drop capable of preventing dryness requires dripping the eye drop into eyes when in use.
4. A method for preparing a clean eye drop capable of preventing dryness is characterized in that:
step 1, preparing pearl liquid, taurine, aspartic acid, vitamin b6, chloramphenicol, borneol, borax and boric acid;
step 2, preparing according to 45-55 parts of boric acid, 15-20 parts of borax and 1-2 parts of borneol; 5-6 parts of chloramphenicol, 4-5 parts of vitamin b6, 3-5 parts of aspartic acid, 8-12 parts of taurine and 5-6 parts of pearl liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811368994.7A CN111195265A (en) | 2018-11-16 | 2018-11-16 | Cleaning type eye drop capable of preventing dryness |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811368994.7A CN111195265A (en) | 2018-11-16 | 2018-11-16 | Cleaning type eye drop capable of preventing dryness |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111195265A true CN111195265A (en) | 2020-05-26 |
Family
ID=70740971
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811368994.7A Pending CN111195265A (en) | 2018-11-16 | 2018-11-16 | Cleaning type eye drop capable of preventing dryness |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111195265A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579358A (en) * | 2008-05-14 | 2009-11-18 | 北京和润创新医药科技发展有限公司 | Ready-to-use traditional Chinese medicine ophthalmic gel |
| CN101890116A (en) * | 2010-02-11 | 2010-11-24 | 姚俊英 | Anthocyanin health-care eye drops and preparation method thereof |
| CN105193850A (en) * | 2014-06-24 | 2015-12-30 | 何建军 | Eye drop prepared from both traditional Chinese medicines and western medicines |
| JP2018002717A (en) * | 2016-06-28 | 2018-01-11 | ライオン株式会社 | Pharmaceutical composition |
-
2018
- 2018-11-16 CN CN201811368994.7A patent/CN111195265A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101579358A (en) * | 2008-05-14 | 2009-11-18 | 北京和润创新医药科技发展有限公司 | Ready-to-use traditional Chinese medicine ophthalmic gel |
| CN101890116A (en) * | 2010-02-11 | 2010-11-24 | 姚俊英 | Anthocyanin health-care eye drops and preparation method thereof |
| CN105193850A (en) * | 2014-06-24 | 2015-12-30 | 何建军 | Eye drop prepared from both traditional Chinese medicines and western medicines |
| JP2018002717A (en) * | 2016-06-28 | 2018-01-11 | ライオン株式会社 | Pharmaceutical composition |
Non-Patent Citations (1)
| Title |
|---|
| 夏路风: "滴眼剂的药物不良反应", 《首都医药》 * |
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|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20200526 |
|
| WD01 | Invention patent application deemed withdrawn after publication |