CN101888992A - 对比剂 - Google Patents

对比剂 Download PDF

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Publication number
CN101888992A
CN101888992A CN2008801149321A CN200880114932A CN101888992A CN 101888992 A CN101888992 A CN 101888992A CN 2008801149321 A CN2008801149321 A CN 2008801149321A CN 200880114932 A CN200880114932 A CN 200880114932A CN 101888992 A CN101888992 A CN 101888992A
Authority
CN
China
Prior art keywords
compound
formula
choh
alkyl
expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2008801149321A
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English (en)
Chinese (zh)
Inventor
V·莫里森-伊夫森
D·G·温
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
GE Healthcare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Publication of CN101888992A publication Critical patent/CN101888992A/zh
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN2008801149321A 2007-11-07 2008-11-06 对比剂 Pending CN101888992A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20075677 2007-11-07
NO20075677 2007-11-07
PCT/EP2008/065042 WO2009060021A1 (en) 2007-11-07 2008-11-06 Contrast agents

Publications (1)

Publication Number Publication Date
CN101888992A true CN101888992A (zh) 2010-11-17

Family

ID=40202036

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801149321A Pending CN101888992A (zh) 2007-11-07 2008-11-06 对比剂

Country Status (5)

Country Link
US (1) US8323619B2 (https=)
EP (1) EP2205553A1 (https=)
JP (1) JP2011504939A (https=)
CN (1) CN101888992A (https=)
WO (1) WO2009060021A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110903275A (zh) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 制备碘比醇的方法、其中间体及其制备方法
CN116891420A (zh) * 2022-07-09 2023-10-17 重庆圣华曦药业股份有限公司 一种碘普罗胺杂质d的合成方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102271715A (zh) * 2009-01-09 2011-12-07 通用电气医疗集团股份有限公司 对比剂组合物
KR101209633B1 (ko) * 2009-09-09 2012-12-06 주식회사 휴메딕스 페길레이션된 삼요오드화 아릴 화합물 및 그를 포함하는 ｘ-선 조영제
US8722020B2 (en) * 2010-03-31 2014-05-13 General Electric Company Hydroxylated contrast enhancement agents

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013616A1 (en) * 2001-08-03 2003-02-20 Bracco Imaging S.P.A. Ionic and non-ionic radiographic contrast agents for use in combined x-ray and nuclear magnetic resonance diagnostics
US20040198834A1 (en) * 2001-10-12 2004-10-07 Lasser Elliott C. Concentrated X-ray contrast media can act as universal antigens and can inhibit or prevent allergic reactions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265610B1 (en) * 1999-01-12 2001-07-24 The University Of North Carolina At Chapel Hill Contrast media for angiography
EP1175392B1 (en) * 1999-04-30 2005-06-22 Amersham Health AS Contrast media

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013616A1 (en) * 2001-08-03 2003-02-20 Bracco Imaging S.P.A. Ionic and non-ionic radiographic contrast agents for use in combined x-ray and nuclear magnetic resonance diagnostics
US20040198834A1 (en) * 2001-10-12 2004-10-07 Lasser Elliott C. Concentrated X-ray contrast media can act as universal antigens and can inhibit or prevent allergic reactions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110903275A (zh) * 2018-09-14 2020-03-24 苏州科伦药物研究有限公司 制备碘比醇的方法、其中间体及其制备方法
CN116891420A (zh) * 2022-07-09 2023-10-17 重庆圣华曦药业股份有限公司 一种碘普罗胺杂质d的合成方法

Also Published As

Publication number Publication date
US8323619B2 (en) 2012-12-04
US20100233097A1 (en) 2010-09-16
EP2205553A1 (en) 2010-07-14
WO2009060021A1 (en) 2009-05-14
JP2011504939A (ja) 2011-02-17

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20101117