CN101880266B - 一种具有抗菌活性的呋喃酮类化合物Cytosporanone A - Google Patents
一种具有抗菌活性的呋喃酮类化合物Cytosporanone A Download PDFInfo
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- CN101880266B CN101880266B CN2010102079433A CN201010207943A CN101880266B CN 101880266 B CN101880266 B CN 101880266B CN 2010102079433 A CN2010102079433 A CN 2010102079433A CN 201010207943 A CN201010207943 A CN 201010207943A CN 101880266 B CN101880266 B CN 101880266B
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- compound
- cytosporanone
- antibacterial
- fungi
- antibacterial activity
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 10
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- 229940049954 penicillin Drugs 0.000 description 3
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- QTENRWWVYAAPBI-YCRXJPFRSA-N streptomycin sulfate Chemical compound OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]1O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](N=C(N)N)[C@H](O)[C@@H](N=C(N)N)[C@H](O)[C@H]1O QTENRWWVYAAPBI-YCRXJPFRSA-N 0.000 description 2
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- 238000001644 13C nuclear magnetic resonance spectroscopy Methods 0.000 description 1
- 238000005160 1H NMR spectroscopy Methods 0.000 description 1
- 238000005084 2D-nuclear magnetic resonance Methods 0.000 description 1
- RZPFVRFSYMUDJO-UHFFFAOYSA-N 2h-naphthalen-1-one Chemical class C1=CC=C2C(=O)CC=CC2=C1 RZPFVRFSYMUDJO-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
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- 241000235819 Cytospora Species 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
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- 238000005481 NMR spectroscopy Methods 0.000 description 1
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- 230000001580 bacterial effect Effects 0.000 description 1
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- 238000013329 compounding Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
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- 229940000406 drug candidate Drugs 0.000 description 1
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- 230000001408 fungistatic effect Effects 0.000 description 1
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- 230000002401 inhibitory effect Effects 0.000 description 1
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- 238000011081 inoculation Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000003120 macrolide antibiotic agent Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
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- 239000003186 pharmaceutical solution Substances 0.000 description 1
- 229920001470 polyketone Polymers 0.000 description 1
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- 229930000044 secondary metabolite Natural products 0.000 description 1
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- 239000000243 solution Substances 0.000 description 1
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- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Description
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2010102079433A CN101880266B (zh) | 2010-06-23 | 2010-06-23 | 一种具有抗菌活性的呋喃酮类化合物Cytosporanone A |
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CN2010102079433A CN101880266B (zh) | 2010-06-23 | 2010-06-23 | 一种具有抗菌活性的呋喃酮类化合物Cytosporanone A |
Publications (2)
Publication Number | Publication Date |
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CN101880266A CN101880266A (zh) | 2010-11-10 |
CN101880266B true CN101880266B (zh) | 2011-12-21 |
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CN2010102079433A Expired - Fee Related CN101880266B (zh) | 2010-06-23 | 2010-06-23 | 一种具有抗菌活性的呋喃酮类化合物Cytosporanone A |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102250978B (zh) * | 2011-07-12 | 2013-02-27 | 江南大学 | 一种发酵法生产2(5)-乙基-4-羟基-5(2)-甲基-3(2h)-呋喃酮的方法 |
CN103864731B (zh) * | 2014-02-19 | 2016-01-20 | 成都中医药大学 | 含季碳手性中心的呋喃内酯环类化合物的合成方法 |
CN108383811B (zh) * | 2018-04-09 | 2020-05-12 | 陕西科技大学 | 一种呋喃酮衍生物及其提取方法和应用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5591872A (en) * | 1993-08-09 | 1997-01-07 | The University Of Iowa Research Foundation | Autoinducer molecule |
CN101468977A (zh) * | 2007-12-28 | 2009-07-01 | 云南省微生物研究所 | 拟茎点霉内酯类化合物 |
-
2010
- 2010-06-23 CN CN2010102079433A patent/CN101880266B/zh not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5591872A (en) * | 1993-08-09 | 1997-01-07 | The University Of Iowa Research Foundation | Autoinducer molecule |
CN101468977A (zh) * | 2007-12-28 | 2009-07-01 | 云南省微生物研究所 | 拟茎点霉内酯类化合物 |
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CB03 | Change of inventor or designer information |
Inventor after: Yi Yanghua Inventor after: Li Ling Inventor after: Zhang Wen Inventor after: Lu Shan Inventor after: Sun Peng Inventor after: Liu Baoshu Inventor after: Tang Hua Inventor before: Yi Yanghua Inventor before: Lu Shan Inventor before: Zhang Wen Inventor before: Li Ling Inventor before: Sun Peng Inventor before: Liu Baoshu Inventor before: Tang Hua |
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COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: YI YANGHUA LU SHAN ZHANG WEN LI LING SUN PENG LIU BAOSHU TANG HUA TO: YI YANGHUA LI LING ZHANG WEN LU SHAN SUN PENG LIU BAOSHU TANG HUA |
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Granted publication date: 20111221 |