CN101869157B - Health-care composition (Parkinson-resistant shockproof health-care tea) for preventing and treating PD (Parkinson Disease) and preparation method thereof - Google Patents
Health-care composition (Parkinson-resistant shockproof health-care tea) for preventing and treating PD (Parkinson Disease) and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a health-care composition (Parkinson-resistant shockproof health-care tea) for preventing and treating PD (Parkinson Disease) and a preparation method thereof, in particular to a health-care composition for preventing and treating PD. The health-care composition is characterized by comprising the following components in proportion by weight: 1-50g of stephania, 1-50g of manyprickle acathopanax root, 1-50g of medlar, 1-50g of paniculate swallowwort root, 1-50g of tea, 1-100ml of royal jelly and 50-600mg of zinc gluconate. The health-care composition is prepared from general traditional Chinese medicines with low price. By fully using and integrating the pharmacologic and nature and flavor functions, the composition prepared from five kinds of traditional Chinese medicines can achieve the therapeutic effect for preventing PD and has the advantages of safety, reliability, no addiction and no side effect.
Description
Affiliated technical field
The present invention relates to a kind of health composition be used to preventing and treating Parkinson's (PD), specifically a kind of with low cost, make simple and easy, the mouthfeel flavor is good and safe and reliable, have no side effect be used for preventing and treating Parkinsonian health composition; The invention still further relates to the manufacture method of above-mentioned health composition.
Background technology
At present, Parkinson's (PD) the incidence of disease has the trend of average annual growth, and the rejuvenation that obviously becomes.This with the change of social pressures, stress, economic pressures, living and diet mode by inseparable relation.
In the medicine for the treatment of at present PD (as Madopar, levodopa etc.), although obtain certain curative effect, curative effect is unstable, the side effect that brings simultaneously is also well-known, and these drug prices are all more expensive, promote the use of in being difficult on a large scale.
The traditional Chinese medical science is thought: the pathology of PD is " all wind trembling and dizziness all belong to liver " briefly; " involve the spleen kidney for a long time, be liver spleen kidney all empty "; " phlegm becomes silted up and becomes a common practice " " asthenia in origin and asthenia in superficiality, excess in the upper and deficiency in the lower "; " rules for the treatment of are calming the liver, nourishing liver and kidney, calming wind and dredging collateral, strengthening the spleen and reducing phlegm is under clear upper the benefit ".
In 100 plurality of Chinese for the treatment of PD, what the frequency of occurrences was the highest has: the kinds more than ten such as ginseng, scorpio, rhizoma Gastrodiae, earthworm, centipede, hippocampus, and these Chinese medicines are expensive, and for general patient, this is not light financial burden.Therefore, select special efficacy and low price, the material preparation that easily obtains has become the task of top priority of control PD.
Summary of the invention
First technical problem that the present invention will solve, be to provide a kind of be used to preventing and treating Parkinsonian health composition, specifically a kind of with low cost, make simple and easy, the mouthfeel flavor is good and safe and reliable, have no side effect be used for preventing and treating Parkinsonian health composition.
Second technical problem that the present invention will solve is to provide a kind of preparation method be used to preventing and treating Parkinsonian health composition.
First technical problem that the present invention will solve, can realize by following technical scheme: a kind of be used to preventing and treating Parkinsonian health composition, it is characterized in that: the composition that comprises following proportioning: Japanese Stephania Root 1-50g, wilsonii 1-50g, fruit of Chinese wolfberry 1-50g, paniculate swallowwort 1-50g, tealeaves 1-50g, royal jelly 1-100ml, zinc gluconate 50-600mg.
As one embodiment of the present of invention, the proportioning of described composition is: Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g, royal jelly 20ml, zinc gluconate 315mg.
The zinc content of described zinc gluconate is 45mg.
Proportioning provided by the invention takes full advantage of and pharmacology and the nature and flavor function of comprehensive various materials, to obtain composition evident in efficacy:
Japanese Stephania Root: Stephamia japonica (Thunb) Miers
Base is former: be root, stem, the leaf of menispermaceae plant Japanese Stephania Root;
Composition and pharmacology: include the multiple biological alkali such as Japanese Stephania Root alkali, have the effect of lax striated muscle and block nerves joint;
Nature and flavor function: little hardship, cold, nontoxic; Have heat-clearing, detoxify, dispel the wind, active effect.
Wilsonii: Acanthopanax Senticosusu (Rupr et Maxim) Harms
Base is former: be root, the skin of Araliaceae wilsonii
Composition and pharmacology: include multiple glucoside, vitamin and sesamin, polysaccharide etc., have than ginseng better " adapting to former " sample effect.So-called " adapting to former " is exactly to make body be in the medicine of " enhancing nonspecific defense capability state ", referred to as SNIR.The characteristics of this class medicine are: the resistivity that strengthens body, as harmful spirit, physical stimulation, as the seven human emotions (happiness anger grief excellent terrified), hot and cold, overweight, overexercise, mandatory motionless etc., and can be life-extending, antiendotoxin, strengthen corticocerebral inhibitory action, increase muscle power, administer;
The nature and flavor function: hot, temperature, nontoxic, have wines used as antirheumatic, strengthen the bone, increase the marrow effect, control muscles and bones contraction urgency, impotence numbness, flaccidity of lower limbs, harmful wind and hurt sb.'s feelings etc.
Paniculate swallowwort: Cynanchum Panicalatum (Bge)
Base is former: be the rhizome of sieve rattan section fabric paniculate swallowwort;
Composition and pharmacology: include the many kinds of substances such as paeonol and acetic acid, cinnamic acid etc., its extract has remarkable minimizing autogenic movement but the effect of not hypnosis;
The nature and flavor function: hot, temperature, nontoxic, have invigorate blood circulation, beneficial gas, by the wind effect, treatment of rheumatalgia pain, irregular menstruation, stable damage, rubella snake venom, the inflatable of suffering from abdominal pain.
The fruit of Chinese wolfberry: Lycium chineuse Mill
Base is former: be the fruit of Solanaceae fabric matrimony vine or lycium barbarum;
Composition and pharmacology: include carrotene, thiamine, riboflavin, Yan acid etc., the hepatonecrosis due to fatty liver, cirrhosis is had obvious repair, neuron is also had obvious repair, therefore also be used for the treatment of the PD due to " the liver wind deficiency of blood ";
The nature and flavor function: sweet, flat, nontoxic, have nourshing kidney moistening lung, tonifying liver, function of improving eyesight, can hard muscle anti-old, except wind benefit people, remove consumptive disease, treat the liver wind deficiency of blood and impotence, faint, contraction etc.
Green tea: Camellia sinensis O Ktze
Base is former: be the bud-leaf of plant of theaceae tea;
Composition and pharmacology: include purine alkaloid, take caffeine, theophylline as main, caffeine can increase the content of dopamine in brain, and can suppress neural endotoxic secretion, thereby dopaminergic neuron is had protective effect, and therefore, long-term drinking green tea can reduce the incidence of disease of PD; The nature and flavor function: sweet, cool, nontoxic, have sharp large intestine, refresh oneself, eliminate effect thirsty and that separate endogenous toxic material.
Zinc gluconate:
Composition and pharmacology: zinc is contained micro-most important a kind of in human body, and it is relevant with activity or the structure of 200 plurality of enzymes, it be anti-ageing, promote body's immunity, improve the important element of anti-virus ability.The Hansen of domestic appropriate authority and the U.S. etc. study discovery, and the serum zinc in the especially Parkinsonian patient of senile dementia, depression is starkly lower than the normal person.Therefore zinc supplementation becomes one of important means of control PD;
The nature and flavor function: property is flat, little hardship, nontoxic, has the body immunity of increasing, delays senility, increases intelligence, promotes the multiple effect of nerve recovery and wound healing.
Royal jelly: Apis cerana Fabrieius
Base is former: be the milky jelly of the worker bee glandulae pharyngeae of Apidae insect apis cerana secretion;
Composition and pharmacology: include fructose, glucose, sucrose, polysaccharide, amino acid, vitamin, pantothenic acid, folic acid, creatine, especially contain a kind of special fatty W-hydroxyl-Δ
2-decylenic acid, content are quite high.Royal jelly can effectively be strengthened the resistance of body and promote growth, anti-anoxic, heat-resisting ability strengthen to some extent, promote cytothesis, promote new cell to replace senile cell, go out damaged cell recovery to the greatest extent, senile dementia, depression, neurosis are improved significantly.Can make the patient brace up, happy, have antibiotic, antiviral, anticancer, sedation concurrently, hypoglycemic, hypotensive, the sexual gland of promotion secretion is especially arranged.Be of great benefit to therefore PD patient's clinical symptoms are improved, and need not to take female hormone and cause unnecessary side effect;
The nature and flavor function: sweet, sour, flat, nontoxic, it has nourishing, strong, beneficial liver, invigorating the spleen, the effect of detoxifying, promote longevity.
For improving mouthfeel and the taste of this health composition when taking, under the prerequisite of the function that does not affect this health composition, the present invention can do following improvement: also comprise powdered sugar 5g.
On the basis of the above, the present invention can also do further improvement: also comprise appropriate excipient; So that health composition of the present invention is made be convenient for carrying, the graininess of taking convenience.
Do not affect under the prerequisite of function of this health composition, the present invention also can improve by following embodiment mouthfeel and the taste of health composition when taking, and comprises honey 10ml and appropriate maltose.
On the basis of the above, the present invention can also do further improvement: also comprise appropriate anticorrisive agent.
Second technical problem that the present invention will solve, can realize by following technical scheme: a kind of preparation method be used to preventing and treating Parkinsonian health composition, it is characterized in that: at first Japanese Stephania Root 1-50g, wilsonii 1-50g, fruit of Chinese wolfberry 1-50g, paniculate swallowwort 1-50g, tealeaves 1-50g are added decocting and become liquid, remove slag filter after, again liquid is fried in shallow oil into thick paste, then add royal jelly 1-100ml, zinc gluconate 50-600mg.
One embodiment of the present of invention: at first Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g are added water 300ml and fry in shallow oil into liquid, after the filtration of removing slag, then liquid is fried in shallow oil into thick paste, then add royal jelly 20ml, zinc gluconate 315mg.
The zinc content of the zinc gluconate that adopts is 45mg.
Be mouthfeel, the taste that improves this health composition, and conveniently take, can be made into health protection tea, as one embodiment of the present of invention: add powdered sugar 5g when adding royal jelly and zinc gluconate, then add appropriate excipient and carry out drying and process, being blow molded at last particle.
The present invention also provides another embodiment, and this health composition is made sweet cream, obtains better mouthfeel and taste: add honey 10ml and appropriate maltose to 60ml when adding royal jelly and zinc gluconate, then add anticorrisive agent.After completing, to the sterilization that carries out disinfection of sweet cream, then packing gets final product.
Health composition provided by the invention is comprised of common, cheap Chinese medicine, owing to taking full advantage of and pharmacology and the nature and flavor function of comprehensive various materials, the composition that five kinds of Chinese medicines of the present invention obtain can reach and prevent Parkinsonian curative effect, and is safe and reliable, without habituation, have no side effect.These materials are easy to get, and are with low cost, and make simply, and can add other compositions that are used for allotment composition mouthfeel and taste according to different needs.Health composition provided by the invention can be prevented and treated electric shock, stable to the curative effect of PD, takes effect rapidly, can reach the effect for the treatment of both principal and secondary aspect of disease.
The specific embodiment
Embodiment 1
What the present embodiment provided is the shockproof health protection tea of anti-handkerchief for preventing and treating Parkinsonian health composition, it is granules of sugar, the composition that comprises following proportioning: Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g, royal jelly 20ml, zinc gluconate 315mg, powdered sugar 5g and appropriate excipient, wherein the zinc content of zinc gluconate is 45mg.
The health composition of the present embodiment is fit to make and is easy to carry about with one, the particle () that the anti-handkerchief of taking convenience is shockproof.Component according to the final health composition that obtains of above-mentioned proportioning is applicable to ordinary people's consumption of three times of a day, should take after the meal.
Embodiment 2
What the present embodiment provided is the shockproof health honeyed cream of anti-handkerchief for preventing and treating Parkinsonian health composition, it is sweet paste, comprises the composition of following proportioning: Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g, royal jelly 20ml, zinc gluconate 315mg, honey 10ml, appropriate maltose and appropriate anticorrisive agent; Wherein the component of maltose can add according to different demands, to reach the effect that is fit to different tastes and mouthfeel.
The health composition of the present embodiment is fit to make mouthfeel and the more excellent sweet paste of taste, and the component according to the final health composition that obtains of above-mentioned proportioning is applicable to ordinary people's consumption of three times of a day, should take after the meal.
Embodiment 3
The preparation method who is used for preventing and treating Parkinsonian health composition that the present embodiment provides, at first Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g are added water 300ml and fry in shallow oil into liquid, remove slag filter after, liquid is fried in shallow oil into thick paste, then add royal jelly 20ml, zinc gluconate 315mg and powdered sugar 5g, wherein the zinc content of zinc gluconate is 45mg; Add at last appropriate excipient and carry out drying and process, being blow molded at last particle.
Component according to the final health composition for preparing of above-mentioned proportioning is applicable to ordinary people's consumption of three times of a day, should take after the meal.
Embodiment 4
At first the preparation method who is used for preventing and treating Parkinsonian health composition that embodiment provides adds water 300ml with Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g and fries in shallow oil into liquid; Remove slag after filtration, liquid is fried in shallow oil into thick paste; Then add royal jelly 20ml, zinc gluconate 315mg (zinc content is 45mg) and honey 10ml, then add maltose to 60ml, and add appropriate anticorrisive agent, make sweet cream.Last sweet cream is after disinfection, and bottling seals.
Component according to the final health composition for preparing of above-mentioned proportioning is applicable to ordinary people's consumption of three times of a day, should take after the meal.
Health composition provided by the invention all has obvious prevent attacks and therapeutic action to various PD patient of each phase:
1, clinical practice:
First: 109 routine PD patients are taken the efficacy analysis of three days continuously:
Wherein remarkable 50 examples, account for 45.8%; Effective 42 examples account for 38.5%; Invalid 17 examples account for 15.5%; Total effective rate is 84.5%.
Second: 109 routine PD patients are taken the efficacy analysis of month continuously:
Wherein remarkable 58 examples, account for 53.2%; Effective 41 examples account for 37.6%; Invalid 10 examples account for 9%; Total effective rate is 91.7%.
Third: 109 routine PD patients are taken trimestral efficacy analysis continuously:
Cure 60 examples its near-mid term, accounts for 55%; Remarkable 33 examples account for 30%; Effective 12 examples account for 11%; Invalid 4 examples account for 3.6%; Total effective rate is 96.4%.
2, clinical analysis:
(1) doing well,improving is sorted out: improving maximum be static tremor, accounts for 92%, is secondly muscular rigidity, accounts for 88%, and constipation accounts for 84%, and step appearance shakiness accounts for 81%, and dysarthrosis accounts for 60%, and pharynx gulps down difficulty, salivate and account for 53%, and small letter disease accounts for 49%, dementia 32%.
(2) early stage patient is efficient is 100%, and the efficient of end-stage patients accounts for 54%.
(3) the efficient of primary patient PD is 98.5%, and the efficient of the comprehensive patient of Secondary cases PD is 81%; Heredity PD patient's the efficient of efficient 78%, the PD of being plus syndrome patient is 49%.
(4) in 109 routine patients, all require the existing Western medicine that takes (as Madopar etc.) successively to successively decrease, after the graininess health composition of taking continuously two months embodiment 1, three month, except the late period serious patient, most of (64%) all withdraws Western medicine, and changes this health composition of Tonga that takes traditional Chinese medicine.
(5) female patient's curative effect of taking the sweet paste health-care combination phenology of embodiment 2 slightly is better than male patient, and this has the effect of female hormone sample relevant with royal jelly, wilsonii.
(6) Time of Administration is longer, and curative effect is more remarkable, and the state of an illness is more stable, this with body in content of zinc replenished and to reach certain value relevant.
(7) health composition provided by the invention is because of energy:
Calming the liver: the merit of paniculate swallowwort, the fruit of Chinese wolfberry, zinc gluconate; Nourishing liver and kidney: the merit of wilsonii, the fruit of Chinese wolfberry, royal jelly; Calming wind and dredging collateral: the merit of Japanese Stephania Root, paniculate swallowwort, zinc gluconate; Invigorating the spleen is by wet: the merit of royal jelly, the fruit of Chinese wolfberry, Japanese Stephania Root, tealeaves, wilsonii; On clear: the merit of Japanese Stephania Root, tealeaves; Under benefit: the merit of wilsonii, royal jelly; Remove endotoxin: the merit of Japanese Stephania Root, the fruit of Chinese wolfberry, wilsonii; And mark: (zinc gluconate, Japanese Stephania Root, paniculate swallowwort, tealeaves) this (wilsonii, royal jelly, the fruit of Chinese wolfberry) double controlling; Therefore can obtain satisfied curative effect.
Composition provided by the invention is for the health care function, and in curative effect PD process, suggestion is synchronizeed with Western medicine, and follows the principle of the convention amount of Western medicine---decrement---full cut-off; As add with the traditional Chinese herbal decoction treatment, also should the vary with each individual side's of executing medicine and this composition are with clothes; In the relatively stable stage after sick stage or process treatment, can use separately this health composition at the beginning of PD is in rudiment.
Claims (3)
1. one kind is used for preventing and treating Parkinsonian health composition, and it is characterized in that: raw material is grouped into by the one-tenth of following proportioning: Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g, royal jelly 20ml, zinc gluconate 315mg; The zinc content of described zinc gluconate is 45mg;
Preparation method: at first Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g are added water 300ml and fry in shallow oil into liquid, after the filtration of removing slag, then liquid is fried in shallow oil into thick paste, then add royal jelly 20ml, zinc gluconate 315mg.
2. one kind is used for preventing and treating Parkinsonian health composition, and it is characterized in that: raw material is grouped into by the one-tenth of following proportioning: Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g, royal jelly 20ml, zinc gluconate 315mg, powdered sugar 5g, appropriate excipient; The zinc content of described zinc gluconate is 45mg;
Preparation method: at first Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g are added water 300ml and fry in shallow oil into liquid, remove slag filter after, again liquid is fried in shallow oil into thick paste, then add royal jelly 20ml, zinc gluconate 315mg and powdered sugar 5g, then add appropriate excipient and carry out drying and process, being blow molded at last particle.
3. one kind is used for preventing and treating Parkinsonian health composition, and it is characterized in that: raw material is grouped into by the one-tenth of following proportioning: Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g, royal jelly 20ml, zinc gluconate 315mg, honey 10ml, appropriate maltose and anticorrisive agent; The zinc content of described zinc gluconate is 45mg;
Preparation method: at first Japanese Stephania Root 10g, wilsonii 10g, fruit of Chinese wolfberry 10g, paniculate swallowwort 10g, green tea 5g are added water 300ml and fry in shallow oil into liquid, remove slag filter after, again liquid is fried in shallow oil into thick paste, then add royal jelly 20ml, zinc gluconate 315mg, then honey 10ml and appropriate maltose add appropriate anticorrisive agent to 60ml.
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| CN2010102098754A CN101869157B (en) | 2010-06-25 | 2010-06-25 | Health-care composition (Parkinson-resistant shockproof health-care tea) for preventing and treating PD (Parkinson Disease) and preparation method thereof |
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|---|---|---|---|---|
| CN1386517A (en) * | 2001-05-17 | 2002-12-25 | 济南市中心医院 | Medicine for treating Parkinson's disease and its preparing process |
| CN101104033A (en) * | 2007-07-03 | 2008-01-16 | 深圳市思沃生命科学技术有限公司 | Traditional Chinese medicinal preparation for treating Parkinson's disease and preparing process thereof |
| CN101480471A (en) * | 2009-01-24 | 2009-07-15 | 彭都 | Medicament for treating parkinson's disease and preparation method thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1386517A (en) * | 2001-05-17 | 2002-12-25 | 济南市中心医院 | Medicine for treating Parkinson's disease and its preparing process |
| CN101104033A (en) * | 2007-07-03 | 2008-01-16 | 深圳市思沃生命科学技术有限公司 | Traditional Chinese medicinal preparation for treating Parkinson's disease and preparing process thereof |
| CN101480471A (en) * | 2009-01-24 | 2009-07-15 | 彭都 | Medicament for treating parkinson's disease and preparation method thereof |
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| Title |
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| 胡方波.中医治疗帕金森病进展.《实用中医药杂志》.2010,第26卷(第5期),350-351. * |
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