CN101869111A - 一种含香菇多糖和三氮唑核苷的抗植物病毒病组合物及其应用 - Google Patents
一种含香菇多糖和三氮唑核苷的抗植物病毒病组合物及其应用 Download PDFInfo
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- CN101869111A CN101869111A CN201010226519A CN201010226519A CN101869111A CN 101869111 A CN101869111 A CN 101869111A CN 201010226519 A CN201010226519 A CN 201010226519A CN 201010226519 A CN201010226519 A CN 201010226519A CN 101869111 A CN101869111 A CN 101869111A
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- Prior art keywords
- ribavirin
- lentinan
- composition
- virus
- sodium sulfate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 title claims abstract description 52
- 229960000329 ribavirin Drugs 0.000 title claims abstract description 51
- HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 title claims abstract description 51
- 229920001491 Lentinan Polymers 0.000 title claims abstract description 48
- 229940115286 lentinan Drugs 0.000 title claims abstract description 48
- 239000000203 mixture Substances 0.000 title claims abstract description 44
- 241000700605 Viruses Species 0.000 title claims abstract description 35
- 201000010099 disease Diseases 0.000 title claims abstract description 18
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 18
- 239000000843 powder Substances 0.000 claims abstract description 11
- 235000007688 Lycopersicon esculentum Nutrition 0.000 claims abstract description 8
- 240000003768 Solanum lycopersicum Species 0.000 claims abstract description 8
- 241000208125 Nicotiana Species 0.000 claims abstract description 7
- 235000002637 Nicotiana tabacum Nutrition 0.000 claims abstract description 7
- 239000007921 spray Substances 0.000 claims abstract description 5
- 239000004480 active ingredient Substances 0.000 claims abstract description 3
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 claims description 22
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 230000002507 anti-phytoviral effect Effects 0.000 claims description 12
- 239000005995 Aluminium silicate Substances 0.000 claims description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 10
- 235000012211 aluminium silicate Nutrition 0.000 claims description 10
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 10
- 238000009736 wetting Methods 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 8
- 238000002360 preparation method Methods 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 6
- 230000036039 immunity Effects 0.000 abstract description 2
- 230000002265 prevention Effects 0.000 abstract description 2
- 230000009385 viral infection Effects 0.000 abstract 1
- 239000004563 wettable powder Substances 0.000 abstract 1
- 241000723873 Tobacco mosaic virus Species 0.000 description 9
- GQPLMRYTRLFLPF-UHFFFAOYSA-N Nitrous Oxide Chemical compound [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 8
- 241000724252 Cucumber mosaic virus Species 0.000 description 7
- 239000002904 solvent Substances 0.000 description 6
- 208000036142 Viral infection Diseases 0.000 description 5
- 230000003612 virological effect Effects 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 241000709992 Potato virus X Species 0.000 description 2
- 230000000840 anti-viral effect Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000005457 optimization Methods 0.000 description 2
- AUHDWARTFSKSAC-HEIFUQTGSA-N (2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-(6-oxo-1H-purin-9-yl)oxolane-2-carboxylic acid Chemical compound [C@]1([C@H](O)[C@H](O)[C@@H](CO)O1)(N1C=NC=2C(O)=NC=NC12)C(=O)O AUHDWARTFSKSAC-HEIFUQTGSA-N 0.000 description 1
- 241000221198 Basidiomycota Species 0.000 description 1
- 101710088194 Dehydrogenase Proteins 0.000 description 1
- 208000005176 Hepatitis C Diseases 0.000 description 1
- 208000007514 Herpes zoster Diseases 0.000 description 1
- 208000000440 Herpetic Stomatitis Diseases 0.000 description 1
- GRSZFWQUAKGDAV-UHFFFAOYSA-N Inosinic acid Natural products OC1C(O)C(COP(O)(O)=O)OC1N1C(NC=NC2=O)=C2N=C1 GRSZFWQUAKGDAV-UHFFFAOYSA-N 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 206010067152 Oral herpes Diseases 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 208000002606 Paramyxoviridae Infections Diseases 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 241001492261 Pleurotaceae Species 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- ABUGVBRDFWGJRD-CHOYNLESSA-N [9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-methyloxolan-2-yl]-2-(2,4-dinitrophenyl)sulfanylpurin-6-yl] [hydroxy(phosphonooxy)phosphoryl] hydrogen phosphate Chemical compound O[C@@H]1[C@H](O)[C@@H](C)O[C@H]1N1C2=NC(SC=3C(=CC(=CC=3)[N+]([O-])=O)[N+]([O-])=O)=NC(OP(O)(=O)OP(O)(=O)OP(O)(O)=O)=C2N=C1 ABUGVBRDFWGJRD-CHOYNLESSA-N 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000003443 antiviral agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 241001493065 dsRNA viruses Species 0.000 description 1
- 206010016165 failure to thrive Diseases 0.000 description 1
- RQFCJASXJCIDSX-UUOKFMHZSA-N guanosine 5'-monophosphate Chemical compound C1=2NC(N)=NC(=O)C=2N=CN1[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]1O RQFCJASXJCIDSX-UUOKFMHZSA-N 0.000 description 1
- 235000013928 guanylic acid Nutrition 0.000 description 1
- 239000004226 guanylic acid Substances 0.000 description 1
- 230000007236 host immunity Effects 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 206010022000 influenza Diseases 0.000 description 1
- 235000013902 inosinic acid Nutrition 0.000 description 1
- 239000004245 inosinic acid Substances 0.000 description 1
- 229940028843 inosinic acid Drugs 0.000 description 1
- 229940079322 interferon Drugs 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000012744 reinforcing agent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 241000701161 unidentified adenovirus Species 0.000 description 1
- 229940100050 virazole Drugs 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (9)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN2010102265193A CN101869111B (zh) | 2010-07-14 | 2010-07-14 | 一种含香菇多糖和三氮唑核苷的抗植物病毒病组合物及其应用 |
Applications Claiming Priority (1)
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CN2010102265193A CN101869111B (zh) | 2010-07-14 | 2010-07-14 | 一种含香菇多糖和三氮唑核苷的抗植物病毒病组合物及其应用 |
Publications (2)
Publication Number | Publication Date |
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CN101869111A true CN101869111A (zh) | 2010-10-27 |
CN101869111B CN101869111B (zh) | 2012-10-31 |
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CN2010102265193A Active CN101869111B (zh) | 2010-07-14 | 2010-07-14 | 一种含香菇多糖和三氮唑核苷的抗植物病毒病组合物及其应用 |
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CN (1) | CN101869111B (zh) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102047883A (zh) * | 2011-01-26 | 2011-05-11 | 山东圣鹏农药有限公司 | 一种含香菇多糖和芸苔素内酯的抗植物病毒病组合物及其应用 |
CN103190404A (zh) * | 2013-04-02 | 2013-07-10 | 中国农业科学院植物保护研究所 | 一种防治植物线虫和病毒病的组合物及其应用 |
CN103719088A (zh) * | 2013-12-25 | 2014-04-16 | 广西南宁碧湾园林工程有限公司 | 一种防治植物病毒病的生物源农药组合物及其应用 |
CN112841229A (zh) * | 2021-01-27 | 2021-05-28 | 烟台恩倍得化工科技有限公司 | 一种含有菊芋叶提取液的组合物及其制备方法和应用 |
-
2010
- 2010-07-14 CN CN2010102265193A patent/CN101869111B/zh active Active
Non-Patent Citations (1)
Title |
---|
张超 等: "食用菌多糖对植物病毒抑制作用的初步研究", 《安徽农业大学学报》 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102047883A (zh) * | 2011-01-26 | 2011-05-11 | 山东圣鹏农药有限公司 | 一种含香菇多糖和芸苔素内酯的抗植物病毒病组合物及其应用 |
CN103190404A (zh) * | 2013-04-02 | 2013-07-10 | 中国农业科学院植物保护研究所 | 一种防治植物线虫和病毒病的组合物及其应用 |
CN103719088A (zh) * | 2013-12-25 | 2014-04-16 | 广西南宁碧湾园林工程有限公司 | 一种防治植物病毒病的生物源农药组合物及其应用 |
CN103719088B (zh) * | 2013-12-25 | 2015-11-18 | 广西南宁碧湾园林工程有限公司 | 一种防治植物病毒病的生物源农药组合物及其应用 |
CN112841229A (zh) * | 2021-01-27 | 2021-05-28 | 烟台恩倍得化工科技有限公司 | 一种含有菊芋叶提取液的组合物及其制备方法和应用 |
CN112841229B (zh) * | 2021-01-27 | 2021-12-28 | 烟台恩倍得化工科技有限公司 | 一种含有菊芋叶提取液的组合物及其制备方法和应用 |
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Publication number | Publication date |
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CN101869111B (zh) | 2012-10-31 |
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Address after: 272000 Yutun Town Residence, Rencheng District, Jining City, Shandong Province (Yutun Industrial Park) Patentee after: SHANDONG SHENGPENG TECHNOLOGY CO.,LTD. Address before: 272063 resident of yutun Town, Rencheng District, Jining City, Shandong Province Patentee before: SHANDONG SHENGPENG PESTICIDE Co.,Ltd. |
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CP03 | Change of name, title or address | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: An anti plant virus disease composition containing lentinan and ribavirin and its application Effective date of registration: 20221114 Granted publication date: 20121031 Pledgee: Jining Rushang Village Bank Co.,Ltd. Liying sub branch Pledgor: SHANDONG SHENGPENG TECHNOLOGY CO.,LTD. Registration number: Y2022980022000 |
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PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Granted publication date: 20121031 Pledgee: Jining Rushang Village Bank Co.,Ltd. Liying sub branch Pledgor: SHANDONG SHENGPENG TECHNOLOGY CO.,LTD. Registration number: Y2022980022000 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right |