CN101855346A - Pkib和naaladl2用作前列腺癌治疗和诊断的靶基因 - Google Patents

Pkib和naaladl2用作前列腺癌治疗和诊断的靶基因 Download PDF

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Publication number
CN101855346A
CN101855346A CN200880109851A CN200880109851A CN101855346A CN 101855346 A CN101855346 A CN 101855346A CN 200880109851 A CN200880109851 A CN 200880109851A CN 200880109851 A CN200880109851 A CN 200880109851A CN 101855346 A CN101855346 A CN 101855346A
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Prior art keywords
pkib
naaladl2
prostate cancer
sequence
polypeptide
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Pending
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CN200880109851A
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English (en)
Chinese (zh)
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中村佑辅
中川英刀
中鹤修一
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Oncotherapy Science Inc
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Oncotherapy Science Inc
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Publication of CN101855346A publication Critical patent/CN101855346A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN200880109851A 2007-08-24 2008-08-20 Pkib和naaladl2用作前列腺癌治疗和诊断的靶基因 Pending CN101855346A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US95785307P 2007-08-24 2007-08-24
US60/957,853 2007-08-24
US3603008P 2008-03-12 2008-03-12
US61/036,030 2008-03-12
PCT/JP2008/065234 WO2009028521A1 (en) 2007-08-24 2008-08-20 Pkib and naaladl2 for target genes of prostate cancer therapy and diagnosis

Publications (1)

Publication Number Publication Date
CN101855346A true CN101855346A (zh) 2010-10-06

Family

ID=40387239

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880109851A Pending CN101855346A (zh) 2007-08-24 2008-08-20 Pkib和naaladl2用作前列腺癌治疗和诊断的靶基因

Country Status (10)

Country Link
US (1) US20120022128A1 (https=)
EP (1) EP2195425A4 (https=)
JP (1) JP2010536365A (https=)
KR (1) KR20100075452A (https=)
CN (1) CN101855346A (https=)
BR (1) BRPI0815757A2 (https=)
CA (1) CA2697512A1 (https=)
RU (1) RU2010111116A (https=)
TW (1) TW200920405A (https=)
WO (1) WO2009028521A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112795650A (zh) * 2014-01-03 2021-05-14 皇家飞利浦有限公司 使用靶基因表达的数学建模评价pi3k细胞信号传导途径活性

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Publication number Priority date Publication date Assignee Title
US8945848B2 (en) * 2009-07-31 2015-02-03 Chromocell Corporation Methods and compositions for identifying and validating modulators of cell fate
KR101164645B1 (ko) * 2011-10-07 2012-07-20 대한민국 Ｇｃｐⅱ 돌연변이를 함유하는 알츠하이머 예방 및 치료용 약학적 조성물
GB201303308D0 (en) * 2013-02-25 2013-04-10 Oxford Biotherapeutics Ltd Therapeutic and diagnostic target
GB201304612D0 (en) * 2013-03-14 2013-05-01 Cancer Rec Tech Ltd Diagnostic and prognostic biomarkers for prostate cancer and other disorders
KR101824303B1 (ko) 2015-08-06 2018-01-31 부경대학교 산학협력단 종이형 전립선암 진단센서, 이의 제조방법, 및 이를 이용한 전립선암 진단방법
CN114177296B (zh) * 2021-12-16 2023-05-26 上海交通大学医学院附属第九人民医院 Mpc的过表达或活性提高在制备预防和/或治疗前列腺癌的药物中的应用

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112795650A (zh) * 2014-01-03 2021-05-14 皇家飞利浦有限公司 使用靶基因表达的数学建模评价pi3k细胞信号传导途径活性

Also Published As

Publication number Publication date
RU2010111116A (ru) 2011-09-27
TW200920405A (en) 2009-05-16
WO2009028521A1 (en) 2009-03-05
US20120022128A1 (en) 2012-01-26
CA2697512A1 (en) 2009-03-05
JP2010536365A (ja) 2010-12-02
EP2195425A4 (en) 2011-01-19
KR20100075452A (ko) 2010-07-02
BRPI0815757A2 (pt) 2015-02-18
EP2195425A1 (en) 2010-06-16

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Application publication date: 20101006