CN101844738A - Preparation method of sealing type injection without crumbs - Google Patents
Preparation method of sealing type injection without crumbs Download PDFInfo
- Publication number
- CN101844738A CN101844738A CN 201010150882 CN201010150882A CN101844738A CN 101844738 A CN101844738 A CN 101844738A CN 201010150882 CN201010150882 CN 201010150882 CN 201010150882 A CN201010150882 A CN 201010150882A CN 101844738 A CN101844738 A CN 101844738A
- Authority
- CN
- China
- Prior art keywords
- cillin bottle
- vinyl cover
- injection
- bottleneck
- clean
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Landscapes
- Closing Of Containers (AREA)
Abstract
The invention relates to a preparation method of sealing type injection without crumbs, which comprises the following steps: a. cleaning: cleaning vials; b. drying and sterilizing: drying and sterilizing the vials; c. cooling and filling: firstly, cooling the vials and then filling the injection into the vials; d. rubber plugs adding: placing the cleaned and sterilized rubber plugs one by one at the mouths of the vials which have the injection; e. plastic caps adding: placing the cleaned plastic caps one by one on the mouths of the vials which have the rubber plugs; f: capping: pressing the plastic caps to be arranged at the mouths of the vials 1; and the steps of sterilization detection, labeling and group packaging are carried out in a general production area. The invention aims at overcoming the defects of the prior art and provides the preparation method of the sealing type injection without crumbs, which has simplified process and low production cost.
Description
[technical field]
The present invention relates to preparation method of sealing type injection without crumbs, injection can be solid powder-injection, liquid injection or solvent etc.
[background technology]
The existing bottled and leak free method of medical, as shown in Figure 1, add aluminium lid at plug, and when adopting the aluminium lid encapsulation, adding aluminium lid, tightening and have aluminium bits to produce in the aluminium lid process, can produce harmful effect to the processing district cleanliness, also pollute can medicine in the cillin bottle easily, for guaranteeing to reach the cleanliness requirement, will increase productive costs; Simultaneously in order to use aluminium lid, also to increase at workshop and to wash aluminium lid sterilizing installation and stream of people corridor, increased 100,000 grades of clean district areas, also need to increase decoration cost, over-the-road expense is very high.For this reason, need to improve the Bottle cap structure of existing apothecary jar and simplify existing medical bottle method for packing, cost-cutting is so that the convenience of bottled medical and safe handling.
[summary of the invention]
The objective of the invention is to overcome the deficiencies in the prior art, provide simplified processing and productive costs low preparation method of sealing type injection without crumbs.
In order to solve the problem of above-mentioned existence, the present invention has adopted following technical proposal:
Preparation method of sealing type injection without crumbs comprises the steps:
A cleans: clean cillin bottle 1;
B drying, sterilization: cillin bottle 1 drying, sterilization;
C cooling, can: cool off cillin bottle 1 earlier, again toward cillin bottle 1 interior can injection;
D adds plug: the good plug 21 that will clean, sterilize is placed on the bottleneck of the cillin bottle 1 that is filled with injection in each one by one;
E adds vinyl cover 22: the vinyl cover 22 of cleaning is placed on cillin bottle 1 bottleneck of having put plug 21 well one by one;
F gland: vinyl cover 22 pressed down be installed at cillin bottle 1 bottleneck;
G detects, labels and the packet packaging step in the sterilization of general producing tract.
Preparation method of sealing type injection without crumbs as mentioned above, it is characterized in that vinyl cover 22 inwall middle and lower parts are provided with a plurality of overhead kicks 221, the overhead kick 221 of vinyl cover 22 inwalls is pressed against on the cillin bottle 1 bottleneck upper end-face edge, when pressing down vinyl cover 22, the overhead kick 221 of vinyl cover 22 inwalls slips over cillin bottle 1 lip bottleneck and hooks on the cillin bottle 1 lip bottleneck lower edge, plug 21 at vinyl cover 22 roof pressure lower seals at cillin bottle 1 bottle mouth position.
Preparation method of sealing type injection without crumbs is characterized in that injection raw material elder generation after 100,000 grades of clean areas cleanings, sterilization treatment, divides to install in each cillin bottle 1 after hundred grades of clean area weighings as mentioned above.
The invention has the beneficial effects as follows:
1, use later-model vinyl cover to replace traditional aluminium lid, the aluminium of avoiding existing aluminium lid to prick producing when cover is considered to be worth doing to the pollution of medicine with to the influence of Production Regional cleanliness, existing relatively bottled method can reduce washes aluminium lid, sterilizing installation and stream of people corridor, can reduce the clean area area during actual production, reduce over-the-road expense;
2, can among the present invention, add a cover and gland all be finished under can hundred grades, no longer need to establish in addition 100,000 grades of clean areas, shortened process, reduce trucking expenses, adopt vinyl cover to substitute existing aluminium lid simultaneously, not only the cost of material is low, and add a cover operation and can finish in a step, processing is simple, and convenience has also reduced the production run cost;
3, the present invention can directly obtain existing manufacturing line transformation, on the bundle lid machine on the existing manufacturing line, remove knife, increase a pressing device again, save on the existing processing line and process relevant equipment with aluminium lid, improvement expenses is lower, is convenient to apply fast;
But 4, the present invention's automation, the production efficiency height.
[description of drawings]
The present invention is described in further detail below in conjunction with accompanying drawing.
Fig. 1 is existing medical bottle method for packing general flow chart;
Fig. 2 is a Chinese traditional medicine bottle method for packing general flow chart of the present invention;
Fig. 3 is a Chinese traditional medicine bottle method for packing flow process details drawing of the present invention;
Fig. 4 is plug combination cover structural representation among the present invention;
Fig. 5 is second kind of method for packing flow process of apothecary jar details drawing.
[specific embodiment]
Shown in Fig. 2,3 and 4, preparation method of sealing type injection without crumbs, it comprises the steps:
A cleans: cillin bottle 1 is placed on the belt conveyor, at 100,000 grades of clean area cleanings and cleaning cillin bottle 1, with bottle washing machine the cillin bottle on belt conveyor or the delivery track 1 is cleaned one by one, cleans and divides ultrasonic cleaning; Clean compressed air dries up step;
B drying, sterilization: belt conveyor was sent cillin bottle 1 into sterilizing oven after cleaning was finished, sterilizing oven is between 100,000 grades of clean areas and ten thousand grades of clean areas, in sterilizing oven, finish drying, sterilization process, after finishing belt conveyor with drying after cillin bottle 1 see off, carry out next step processing;
C cooling, can: cool off cillin bottle 1 earlier, again toward cillin bottle 1 interior can injection, its step is as follows: cillin bottle 1 opening is placed on the belt conveyor up, belt conveyor is delivered to cillin bottle 1 on the bottle placer under hundred grades of clean protections, the medicine material packing is earlier 100,000 grades of clean area cleaning packings, sterilization, medicine material can be injections such as liquid drugs injection, powder-injection or solvent; Cooling cillin bottle 1, divide hundred grades of clean area medicine material metering backs then and install in each cillin bottle 1, for example powder-injection can pass through twin screw powder pin bottle placer can medicinal powder in cillin bottle 1, and the cillin bottle 1 that belt conveyor will be equipped with medicine after can is finished is seen off, carries out next step processing;
D adds plug: the good plug 21 that will clean, sterilize is placed on the bottleneck of the cillin bottle 1 that is filled with injection in each one by one, and plug 21 is a butyl rubber plug, and plug 21 is sterilized with the water for injection cleaning and with sterilizing oven at hundred grades of clean areas earlier, cooling then;
E adds vinyl cover 22: the vinyl cover 22 of cleaning is placed on cillin bottle 1 bottleneck of having put plug 21 well one by one, among the present invention, at hundred grades of clean areas, cillin bottle 1 bottleneck is upwards placed, the material loading capping machine is placed on cillin bottle 1 bottle mouth position with vinyl cover 22 earlier, vinyl cover 22 inwall middle and lower parts are provided with a plurality of overhead kicks 221, and the overhead kick 221 of vinyl cover 22 inwalls is pressed against on the cillin bottle 1 bottleneck upper end-face edge;
Vinyl cover 22 also can outward processing, during use vinyl cover 22 vacuum packagings is transported to manufacturing line and directly uses.During actual production, can transport comfort feature and select vinyl cover 22 making manufacturing lines are arranged on the work area of adding a cover of the present invention, perhaps directly vinyl cover 22 is carried out outsourcing processing according to the productive capacity size.
F gland: vinyl cover 22 pressed down be installed at cillin bottle 1 bottleneck; Among the present invention, at hundred grades of clean areas, with the downward compression molding material lid 22 of pressing device, the overhead kick 221 of vinyl cover 22 inwalls slips over cillin bottle 1 lip bottleneck and hooks on the cillin bottle 1 lip bottleneck lower edge, plug 21 at vinyl cover 22 roof pressure lower seals at cillin bottle 1 bottle mouth position, subsequently, the cillin bottle 1 of sealing locking is transmitted band and sends into next step operation.
G detects, labels and the packet packaging step in the sterilization of general producing tract.This step is carried out in general producing tract, if the product needed terminal sterilization carry out sterilization treatment, then label on cillin bottle 1 after the lamp inspection as not needing, packet packaging can be placed supporting papers such as specification sheets certification of fitness in packing box in this step in packing box then.Loading packing back warehouse-in is well deposited.
As shown in Figure 5, second kind of preparation method of sealing type injection without crumbs can realize that equally the chipless of cillin bottle 1 seals.Its step is as follows:
The first step is cleaned: cillin bottle 1 is placed on the belt conveyor, at 100,000 grades of clean area cleanings and cleaning cillin bottle 1, with bottle washing machine the cillin bottle on belt conveyor or the delivery track 1 is cleaned one by one, cleans and divides ultrasonic cleaning; Clean compressed air dries up step;
Dry, the sterilization of second step: belt conveyor was sent cillin bottle 1 into sterilizing oven after cleaning was finished, sterilizing oven is between 100,000 grades of clean areas and ten thousand grades of clean areas, in sterilizing oven, finish drying, sterilization process, after finishing belt conveyor with drying after cillin bottle 1 see off, carry out next step processing;
The cooling of the 3rd step, can: cool off cillin bottle 1 earlier, again toward cillin bottle 1 interior can injection, its step is as follows: cillin bottle 1 opening is placed on the belt conveyor up, belt conveyor is delivered to cillin bottle 1 on the bottle placer under hundred grades of clean protections, the medicine material packing is earlier 100,000 grades of clean area cleaning packings, sterilization, medicine material can be injections such as liquid drugs injection, powder-injection or solvent; Cooling cillin bottle 1, divide hundred grades of clean area medicine material metering backs then and install in each cillin bottle 1, for example powder-injection can pass through twin screw powder pin bottle placer can medicinal powder in cillin bottle 1, and the cillin bottle 1 that belt conveyor will be equipped with medicine after can is finished is seen off, carries out next step processing;
The 4th step combination plug: will clean, the sealing plug 21 that sterilization is good is packed into and is obtained plug combination cover 2 in the clean vinyl cover 22, in the preferred embodiment for the present invention, at hundred grades of clean areas, disappear at plug and to wash the machine exit and be provided with plug vinyl cover unit mahine, sealing plug 21 is a butyl rubber plug, sealing plug 21 cleans and sterilization with water for injection in the plug washing and sterilizing machine in ten thousand grades of clean areas earlier, after the cooling, to clean again, the vinyl cover 22 that sterilization is good is sent into plug vinyl cover unit mahine, will clean by plug vinyl cover unit mahine, the sealing plug 21 that sterilization is good is pressed into and obtains plug combination cover 2 in the vinyl cover 22;
The 5th step added plug combination cover 2: in the preferred embodiment for the present invention, at hundred grades of clean areas, cillin bottle 1 bottleneck is upwards placed, the material loading capping machine is placed on cillin bottle 1 bottle mouth position with plug combination cover 2 earlier, vinyl cover 22 inwall middle and lower parts are provided with a plurality of overhead kicks 221, and the overhead kick 221 of vinyl cover 22 inwalls is pressed against cillin bottle 1 bottle mouth position;
Plug combination cover 2 also can outward processing, during use plug combination cover 2 vacuum packagings that combine is transported to manufacturing line and directly uses.During actual production, can transport comfort feature and select plug combination cover 2 making manufacturing lines are arranged on the work area of adding a cover of the present invention, perhaps directly plug combination cover 2 is made manufacturing lines and carry out outsourcing processing according to the productive capacity size.
The 6th goes on foot gland: plug combination cover 2 is pressed down be installed at cillin bottle 1 bottleneck; Among the present invention, at hundred grades of clean areas, with the downward moulding plug of pressing device combination cover 2, the overhead kick 221 of vinyl cover 22 inwalls slips over cillin bottle 1 lip bottleneck and hooks on the cillin bottle 1 lip bottleneck lower edge, plug 21 at vinyl cover 22 roof pressure lower seals at cillin bottle 1 bottle mouth position.The cillin bottle 1 of band plug combination cover 2 is transmitted band together and sends into next step operation after finishing.
The 7th step was detected, labels and the packet packaging step in the sterilization of general producing tract.This step is carried out in general producing tract, if the product needed terminal sterilization carry out sterilization treatment, then label on cillin bottle 1 after the lamp inspection as not needing, packet packaging can be placed supporting papers such as specification sheets certification of fitness in packing box in this step in packing box then.Loading packing back warehouse-in is well deposited.
Claims (3)
1. preparation method of sealing type injection without crumbs is characterized in that comprising the steps:
(a) clean: clean cillin bottle (1);
(b) dry, sterilization: dry, the sterilization of cillin bottle (1);
(c) cooling, can: cool off cillin bottle (1) earlier, again toward the interior can injection of cillin bottle (1);
(d) add plug: the good plug (21) that will clean, sterilize is placed on the bottleneck of the cillin bottle (1) that is filled with injection in each one by one;
(e) add vinyl cover (22): the vinyl cover (22) of cleaning is placed on cillin bottle (1) bottleneck of having put plug (21) well one by one;
(f) gland: vinyl cover (22) pressed down be installed at cillin bottle (1) bottleneck;
(g) detect, label and the packet packaging step in the sterilization of general producing tract.
2. according to the described preparation method of sealing type injection without crumbs of claim 1, it is characterized in that described vinyl cover (22) inwall middle and lower part is provided with a plurality of overhead kicks (221), the overhead kick (221) of vinyl cover (22) inwall is pressed against on cillin bottle (1) the bottleneck upper end-face edge, when pressing down vinyl cover (22), the overhead kick (221) of vinyl cover (22) inwall slips over cillin bottle (1) lip bottleneck and hooks on cillin bottle (1) the lip bottleneck lower edge, plug (21) at vinyl cover (22) roof pressure lower seal at cillin bottle (1) bottle mouth position.
3. according to the described preparation method of sealing type injection without crumbs of claim 1, it is characterized in that described injection raw material is first after 100,000 grades of clean areas cleanings, sterilization treatment, after hundred grades of clean area weighings, divide to install in each cillin bottle (1).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010150882 CN101844738A (en) | 2010-04-11 | 2010-04-11 | Preparation method of sealing type injection without crumbs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010150882 CN101844738A (en) | 2010-04-11 | 2010-04-11 | Preparation method of sealing type injection without crumbs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN101844738A true CN101844738A (en) | 2010-09-29 |
Family
ID=42769579
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010150882 Pending CN101844738A (en) | 2010-04-11 | 2010-04-11 | Preparation method of sealing type injection without crumbs |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN101844738A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102874422A (en) * | 2012-10-31 | 2013-01-16 | 山东威高集团医用高分子制品股份有限公司 | Production technology of honeycomb type packaging pre-filling sealing penicillin bottle |
| CN104071363A (en) * | 2014-07-04 | 2014-10-01 | 海南通用康力制药有限公司 | Arginine aspirin powder injection split filling process and automatic split filing system thereof |
| CN105539966A (en) * | 2015-12-16 | 2016-05-04 | 温州市吉诺机械有限公司 | Assembling, filling, sealing and labeling assembly line for injector |
| CN107364822A (en) * | 2017-08-25 | 2017-11-21 | 原子高科股份有限公司 | A kind of high-precision radioactivity decoction automatic subpackaging equipment |
| CN109703835A (en) * | 2019-02-27 | 2019-05-03 | 四川制药制剂有限公司 | A method of preparing SC 69124 freeze drying powder injection |
| CN109745231A (en) * | 2019-02-27 | 2019-05-14 | 四川制药制剂有限公司 | A kind of system preparing SC 69124 freeze drying powder injection |
| CN115991453A (en) * | 2023-03-21 | 2023-04-21 | 山东恒智医创医疗器械科技有限公司 | Production process of hydrogen peroxide-containing disinfectant |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN200948241Y (en) * | 2006-09-18 | 2007-09-19 | 中山博泰药械有限公司 | Xilin medicine capsule for injecting |
| CN201258243Y (en) * | 2008-07-25 | 2009-06-17 | 芜湖康奇制药有限公司 | Small capacity injection embedding system |
-
2010
- 2010-04-11 CN CN 201010150882 patent/CN101844738A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN200948241Y (en) * | 2006-09-18 | 2007-09-19 | 中山博泰药械有限公司 | Xilin medicine capsule for injecting |
| CN201258243Y (en) * | 2008-07-25 | 2009-06-17 | 芜湖康奇制药有限公司 | Small capacity injection embedding system |
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102874422A (en) * | 2012-10-31 | 2013-01-16 | 山东威高集团医用高分子制品股份有限公司 | Production technology of honeycomb type packaging pre-filling sealing penicillin bottle |
| CN104071363A (en) * | 2014-07-04 | 2014-10-01 | 海南通用康力制药有限公司 | Arginine aspirin powder injection split filling process and automatic split filing system thereof |
| CN105539966A (en) * | 2015-12-16 | 2016-05-04 | 温州市吉诺机械有限公司 | Assembling, filling, sealing and labeling assembly line for injector |
| CN107364822A (en) * | 2017-08-25 | 2017-11-21 | 原子高科股份有限公司 | A kind of high-precision radioactivity decoction automatic subpackaging equipment |
| CN107364822B (en) * | 2017-08-25 | 2022-09-23 | 原子高科股份有限公司 | Automatic sub-packaging equipment of high accuracy radioactive liquid medicine |
| CN109703835A (en) * | 2019-02-27 | 2019-05-03 | 四川制药制剂有限公司 | A method of preparing SC 69124 freeze drying powder injection |
| CN109745231A (en) * | 2019-02-27 | 2019-05-14 | 四川制药制剂有限公司 | A kind of system preparing SC 69124 freeze drying powder injection |
| CN115991453A (en) * | 2023-03-21 | 2023-04-21 | 山东恒智医创医疗器械科技有限公司 | Production process of hydrogen peroxide-containing disinfectant |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101844738A (en) | Preparation method of sealing type injection without crumbs | |
| CN204938958U (en) | The bottle placer of automatic detection bottle cap | |
| CN204630304U (en) | Infusion preparation plastic bottle vertical type drying machine | |
| CN101687622A (en) | Method and apparatus for the production of packaging units or packages | |
| CN103395501A (en) | Packaging and sealing system for bagged products | |
| CN101830419A (en) | Preparation method of suction-free injection | |
| CN101596941B (en) | Air-exhausting bag clamping device with straw packaging bag and packaging method using same | |
| CN208530973U (en) | It is a kind of for removing the device of cap removing and bottleneck powder | |
| CN102490921B (en) | Intelligent automatic spout cap screwing machine | |
| CN106219474A (en) | A kind of electric mosquito repellent liquid auto-filling packaging production line | |
| CN203005799U (en) | Full-automatic box filler | |
| CN102923625B (en) | Linear multi-station cover taking device | |
| CN206900722U (en) | A kind of fruit wine recrater | |
| CN202828114U (en) | Double-station vacuum seal system for shaping vacuum packaging machine | |
| CN202229889U (en) | Leakage detecting device of soft bag | |
| CN201756197U (en) | Hot shrink film packaging machine | |
| CN204938959U (en) | Bottle placer | |
| CN207465855U (en) | The bicker of embedding plastic bottle is blown for large capacity | |
| CN210883340U (en) | Bottle cap suitable for gasket-free sealing | |
| CN203683063U (en) | Automatic basket-stripping/filling yogurt processing line | |
| CN111874846A (en) | Bottle cap spinning machine capable of detecting sealing performance of plastic bottle | |
| CN110862061A (en) | Bottle assembling machine | |
| CN206732483U (en) | A kind of fully-automatic intelligent is identified into pad machine | |
| CN204624007U (en) | Plug/Aluminum cover cleaner | |
| CN202400298U (en) | Intelligent automatic spout cap tightener |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20100929 |