CN101843932A - Hemoperfusion cartridge - Google Patents
Hemoperfusion cartridge Download PDFInfo
- Publication number
- CN101843932A CN101843932A CN 201010183145 CN201010183145A CN101843932A CN 101843932 A CN101843932 A CN 101843932A CN 201010183145 CN201010183145 CN 201010183145 CN 201010183145 A CN201010183145 A CN 201010183145A CN 101843932 A CN101843932 A CN 101843932A
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- Prior art keywords
- gland
- blood
- cannelure
- perfusion device
- inwall
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- 230000001951 hemoperfusion Effects 0.000 title abstract description 4
- 210000004907 gland Anatomy 0.000 claims abstract description 58
- 239000008280 blood Substances 0.000 claims abstract description 53
- 210000004369 blood Anatomy 0.000 claims abstract description 53
- 230000008081 blood perfusion Effects 0.000 claims description 18
- 239000004744 fabric Substances 0.000 claims description 5
- 210000001503 joint Anatomy 0.000 claims description 3
- 230000007704 transition Effects 0.000 claims description 3
- 230000002093 peripheral effect Effects 0.000 claims description 2
- 238000007789 sealing Methods 0.000 abstract description 15
- 238000003466 welding Methods 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 8
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 230000003044 adaptive effect Effects 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000010412 perfusion Effects 0.000 description 13
- 238000000034 method Methods 0.000 description 4
- 238000000746 purification Methods 0.000 description 4
- 230000001954 sterilising effect Effects 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 239000003463 adsorbent Substances 0.000 description 2
- 230000006698 induction Effects 0.000 description 2
- 208000005189 Embolism Diseases 0.000 description 1
- 231100000643 Substance intoxication Toxicity 0.000 description 1
- 208000001435 Thromboembolism Diseases 0.000 description 1
- 206010070863 Toxicity to various agents Diseases 0.000 description 1
- 235000010599 Verbascum thapsus Nutrition 0.000 description 1
- 244000178289 Verbascum thapsus Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 239000011819 refractory material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 238000009827 uniform distribution Methods 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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Abstract
The invention discloses a hemoperfusion cartridge, which comprises a middle cylinder (1), glands (2), small blood nozzle cap (3) and filter screens. The two ends of the middle cylinder (1) are respectively sealed by one gland (2). A blood nozzle (2a) is arranged in the center of each gland (2) and is sealed by one small blood nozzle cap (3) in a pressing way. One filter screen is respectively installed in the middle cylinder (1) at a position close to the respective gland (2). An annular groove is arranged on the end surface of the opening end of each gland (2). The inner wall of the outer circumference of the annular groove is step-shaped. The end structure of the middle cylinder (1) is adaptive to the annular groove structure. The end (1d) of the middle cylinder is inserted into the annular groove for butt-connection, and the end (1d) of the middle cylinder and the annular groove are ultrasonically welded into a whole body. The invention has the advantages that the structure is simple, the design is unique, the glands and the middle cylinder structure are adaptive to ultrasonic welding, the sealing effect of the welded and formed hemoperfusion cartridge is good and the pollution is not apt to be caused; the small blood nozzle cap and the blood nozzle of the gland have unique three-dimensional sealing effect and the sealing is tight; and the number of components is reduced, the dies are reduced and the production cost and the manufacturing cost are greatly decreased.
Description
Technical field
The present invention relates to a kind of medical apparatus and instruments, relate in particular to the blood perfusion device in blood purification field.
Background technology
In recent years, the blood purification therapy develops rapidly and popularizes in China.Wherein hemoperfusion is one of important way of blood purification.At present, blood perfusion technique is widely used in clinical, not only serious symptom poisonous substance, drug intoxication is had good curative effect, and also can be used for the treatment of many chronic and refractories and difficult disease.So the demand of disposable blood perfusion device increases year by year.
Blood perfusion device is connected in the outer circulation bloody path of lead body in the blood purification process, and adsorbent is with the absorption of the toxicant in the blood when tank body for blood flow, and the blood that is cleaned enters body-internal-circulation again.So the sterilization of perfusion device, the particularly sealing after the sterilization are stored, transportation is extremely important.In the transportation, if the perfusion device is poorly sealed, can cause the material of filling in the air admission perfusion device internal contamination perfusion device, gnotobasis is destroyed, and content can leak out, and causes the perfusion device contaminated equally.
At present, common blood perfusion device all is made up of middle tube, filter screen, end cap, locking nut, block and rubber cushion etc., in assembling, filter screen is contained in the middle tube, end cap (gland) is sealed middle tube, adorn a packing ring between end cap and the middle tube, by locking nut locking, the blood mouth of end cap central authorities is by the rubber cushion press seal in block and the block between end cap and the middle tube.Whole blood perfusion device has 14 primary clusterings, needs 7 molds, more complicated, and production cost is higher.Several seal points of blood perfusion device all are by threaded engagement simultaneously, tighten sealing, and the perfusion device is when sterilization, and owing to certain deformation can appear in high temperature, highly compressed effect, becoming flexible can appear in the cooperation of screw thread, need tighten once more, pollutes.In order to overcome above drawback, the someone attempts that sealing place is rotated friction welding to needs, but in welding process, can produce many flying chips in contact friction moment, and flying chip is on filter screen, in case it is very big to human body harm to enter blood.Also the someone attempts the eddy current welding is carried out in needs sealing place, welding is to heat by the metal induction coil to carry out the plastics fusion weld, because induction coil is concentric with the very difficult assurance in the position of weldment, circumference temp is difficult to consistent, welding effect is difficult to guarantee that waste product is many behind the welding fabrication.In perfusion device field, what sealing structure tank body adopts is the problem that is difficult to solution always.
Summary of the invention
It is a kind of by ultra-sonic welded that technical problem to be solved by this invention is to provide, the blood perfusion device of good sealing effect.
Technical scheme of the present invention is as follows: a kind of blood perfusion device, comprise middle tube, gland, blood mouth small cap and filter screen, its key is: the tube two ends are sealed by a gland respectively in described, described gland central authorities are provided with the blood mouth, this blood mouth is by blood mouth small cap press seal, and filter screen is equipped with at a close gland place separately respectively in the described middle tube; Described gland opening end face has cannelure, described cannelure excircle inwall is a step, the cannelure inner periphery inwall of this gland axially is evenly equipped with rib, tube termination outer circumference surface is the stairstepping that adapts with gland cannelure excircle inwall in described, should insert butt joint in the gland cannelure in middle tube termination, it is one that described middle tube termination outer circumference surface supports ultra-sonic welded by rib.This structure adapts to ultra-sonic welded, tube termination outer circumference surface is for having certain tiny gap with gland cannelure excircle inwall in before welding, middle tube termination inner peripheral surface props up i.e. support by the cannelure inner periphery inwall rib of gland, through ultra-sonic welded, middle tube termination outer circumference surface is for to fuse into one with gland cannelure excircle inwall, the cannelure inner periphery inwall muscle uniform distribution of gland all with to power supports a tube termination outer circumference surface in when welding, in the tube termination can be not inwardly or unbalance stress, situations such as slit appear after making welding one-body molded, the sealing of gland and middle tube is very good, no matter be after sterilization, or the perfusion device all is difficult for polluting in the transportation.
The gland of above-mentioned blood mouth periphery is provided with sheath, and this jacket inner wall is provided with female thread.When the blood mouth is connected with extension tube attached, the screw thread of extension tube attached outer wall and jacket inner wall screw thread threaded engagement, it is more firm to make that the blood mouth is connected with extension tube attached.
Also be provided with the ring set of protection blood mouth on the gland of above-mentioned sheath periphery.Ring set can protect the blood mouth can not be subjected to the external force collision in use or transportation, comes off with extension tube attached, simultaneously because there has been the whole perfusion device of ring set can erect placement, and has increased the aesthetic property of perfusion device.
The top of the screen frame excircle of above-mentioned filter screen is provided with the protruding eaves of a circle, middle tube inwall by described gland is provided with the two-stage step, fit in described first step face and screen frame lower surface, fit in described second step face and protruding eaves lower surface, the transition face between described first step face and the second step face is to fit with the screen frame outer circumference surface of protruding eaves below.Contact position in screen frame and the perfusion device between the tube inwall forms two places and turns round, so adsorbent is difficult for the escaping slot between the tube inwall from screen frame and perfusion device in the process that purifies the blood, causes thromboembolism to jeopardize people's life.
Above-mentioned annular screen frame lower surface has first cannelure, and described screen cloth embeds in first cannelure.Screen cloth and screen frame single injection-molded, screen cloth can be tightened and make in conjunction with more firm.
Above-mentioned blood mouth small cap partly is made up of top enlarged diameter section and bottom reduced diameter section two, described small cap top is that hands is twisted part, the small cap bottom be with gland on the suitable male thread portion of blood mouth, described external thread part is divided into the tubular structure of lower ending opening, described male thread portion upper end closed, the internal diameter of described male thread portion is that the upper end is little, the lower end becomes big taper gradually, and be extended with stopper under the mediad of described male thread portion upper end, described stopper upper end diameter is big, and lower end diameter diminishes gradually and is conical.After blood mouth small cap and gland blood mouth threaded engagement are tightened, 1, the sealing that matches of the big end down tapering of the up-small and down-big tapering of male thread portion internal diameter and blood mouth; 2, the stopper of blood mouth small cap stretches into gland blood mouth oral area endoporus it is sealed; 3, blood mouth small cap inner top surface is pushed down the face seal of gland mouth end, forms three-dimensional sealing, makes that the sealing of blood mouth small cap and gland blood mouth is tight, can not produce pollution.
Above-mentioned stopper lower end surface is spherical.In the process that is screwed into, it is more smooth and easy that stopper enters gland blood mouth.
Beneficial effect: the present invention has simple in structure, design uniqueness, and gland and tube-in-tube structure adapt to ultra-sonic welded, and the perfusion device good sealing effect of welding fabrication is difficult for polluting; It is tight that blood mouth small cap and gland blood mouth have unique tri-dimensional sealed effect sealing; Assembly reduces, and mould reduces, and greatly reduces the cost of the manufacturing.
Description of drawings
Fig. 1 is a structural representation of the present invention;
Fig. 2 is the partial enlarged drawing of A portion among Fig. 1;
Fig. 3 is the partial enlarged drawing of B portion among Fig. 1.
The specific embodiment
The invention will be further described below in conjunction with drawings and Examples:
As Fig. 1, shown in Figure 2, a kind of blood perfusion device, tube 1 in comprising, gland 2, blood mouth small cap 3 and filter screen, tube 1 two ends are sealed by a gland 2 respectively in described, described gland 2 opening end faces have cannelure, described cannelure excircle inwall is a stairstepping, the cannelure inner periphery inwall of this gland 2 axially is evenly equipped with rib 2b, the bar number of rib is 16 or 18 and all can, tube 1 termination outer circumference surface is the stairstepping that adapts with gland 2 cannelure excircle inwalls in described, should insert butt joint in gland 2 cannelures by middle tube 1 termination 1d, it is one that described middle tube 1 termination outer circumference surface supports ultra-sonic welded by rib 2b.Described gland 2 central authorities are provided with blood mouth 2a, described blood mouth small cap 3 partly is made up of top enlarged diameter section and bottom reduced diameter section two, described small cap top is that hands is twisted part 3a, the small cap bottom be with gland on the suitable male thread portion 3b of blood mouth, described male thread portion 3b is the tubular structure of lower ending opening, described male thread portion 3b upper end closed, the internal diameter upper end of described male thread portion 3b is little, it is tapered greatly that the lower end becomes gradually, and be extended with stopper 3c under the mediad of described male thread portion 3b upper end, described stopper 3c upper end diameter is big, and lower end diameter diminishes gradually and is conical, and stopper 3c lower end surface is spherical.This blood mouth 2a cooperates formation tri-dimensional sealed with blood mouth small cap.In order to be connected firmly with external blood tube, the gland 2 of blood mouth 2a periphery is provided with sheath 6 simultaneously, and these sheath 6 inwalls are provided with female thread.Also be provided with the ring set 7 of protection blood mouth 2a on the gland 2 of described sheath 6 peripheries.Filter screen is equipped with at tube 1 interior close gland 2 places separately respectively in described; The top of screen frame 4 excircles of filter screen is provided with the protruding eaves 4a of a circle, (referring to Fig. 2) is provided with the two-stage step by middle tube 1 inwall of described gland 2, fit in described first step face 1a and screen frame 4 lower surfaces, fit in described second step face 1b and protruding eaves 4a lower surface, the transition face between described first step face 1a and the second step face 1b is that screen frame 4 outer circumference surfaces of 1c and protruding eaves 4a below are fitted.Screen frame 4 upper surfaces are spacing by gland, and the lower surface is spacing by first step face 1a, and filter screen is stuck in the middle tube firmly.Annular screen frame 4 lower surfaces have the first cannelure 4b, and described screen cloth 5 edges of crossing embed in the first cannelure 4b single injection-molded, sound construction.
Although below in conjunction with the accompanying drawings the preferred embodiments of the present invention are described; but the invention is not restricted to the above-mentioned specific embodiment; the above-mentioned specific embodiment only is schematic rather than determinate; those of ordinary skill in the art is under enlightenment of the present invention; under the prerequisite of aim of the present invention and claim; can make multiple similar expression, such conversion all falls within protection scope of the present invention.
Claims (7)
1. blood perfusion device, comprise middle tube (1), gland (2), blood mouth small cap (3) and filter screen, it is characterized in that: tube (1) two ends are sealed by a gland (2) respectively in described, described gland (2) central authorities are provided with blood mouth (2a), this blood mouth (2a) is by blood mouth small cap (3) press seal, and close gland (2) separately locates to be equipped with respectively filter screen in the described middle tube (1); Described gland (2) opening end face has cannelure, the cannelure excircle inwall of described gland (2) is a stairstepping, the cannelure inner periphery inwall of this gland (2) axially is evenly equipped with rib (2b), tube (1) termination outer circumference surface is the stairstepping that adapts with gland (2) cannelure excircle inwall in described, should insert butt joint in gland (2) cannelure in middle tube (a 1) termination (1d), it is one that described middle tube (1) termination outer circumference surface supports ultra-sonic welded by rib (2b).
2. according to the described blood perfusion device of claim 1, it is characterized in that: the peripheral gland (2) of described blood mouth (2a) is provided with sheath (6), and this sheath (6) inwall is provided with female thread.
3. according to the described blood perfusion device of claim 2, it is characterized in that: the ring set (7) that also is provided with protection blood mouth (2a) on the gland (2) of described sheath (6) periphery.
4. according to the described blood perfusion device of claim 1, it is characterized in that: the top of the screen frame of described filter screen (4) excircle is provided with a circle protruding eaves (4a), middle tube (1) inwall by described gland (2) is provided with the two-stage step, described first step face (1a) is fitted with screen frame (4) lower surface, described second step face (1b) is fitted with protruding eaves (4a) lower surface, and the transition face between described first step face (1a) and the second step face (1b) is that (1c) fits with screen frame (4) outer circumference surface of protruding eaves (4a) below.
5. according to claim 1 or 4 described blood perfusion devices, it is characterized in that: described annular screen frame (4) lower surface has first cannelure (4b), and described screen cloth (5) embeds in first cannelure (4b).
6. according to the described blood perfusion device of claim 1, it is characterized in that: described blood mouth small cap (3) partly is made up of top enlarged diameter section and bottom reduced diameter section two, described small cap top is that hands is twisted part (3a), the small cap bottom be with gland on the suitable male thread portion (3b) of blood mouth, described male thread portion (3b) is the tubular structure of lower ending opening, described male thread portion (3b) upper end closed, the internal diameter of described male thread portion (3b) is that the upper end is little, it is tapered greatly that the lower end becomes gradually, and be extended with stopper (3c) under the mediad of described male thread portion (3b) upper end, described stopper (3c) upper end diameter is big, and lower end diameter diminishes gradually and is conical.
7. according to the described blood perfusion device of claim 6, it is characterized in that: described stopper (3c) lower end surface is for spherical.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010101831451A CN101843932B (en) | 2010-05-26 | 2010-05-26 | Hemoperfusion cartridge |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2010101831451A CN101843932B (en) | 2010-05-26 | 2010-05-26 | Hemoperfusion cartridge |
Publications (2)
Publication Number | Publication Date |
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CN101843932A true CN101843932A (en) | 2010-09-29 |
CN101843932B CN101843932B (en) | 2012-06-27 |
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CN2010101831451A Active CN101843932B (en) | 2010-05-26 | 2010-05-26 | Hemoperfusion cartridge |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102488933A (en) * | 2011-12-12 | 2012-06-13 | 重庆希尔康血液净化器材研发有限公司 | Blood perfusion device |
CN103845767A (en) * | 2012-12-03 | 2014-06-11 | 于杰 | Blood perfusion device for experimental animals |
CN110314259A (en) * | 2019-07-24 | 2019-10-11 | 广州康盛生物科技有限公司 | Perfusion device |
CN110448750A (en) * | 2019-07-26 | 2019-11-15 | 北京中科盛康科技有限公司 | A kind of blood perfusion device |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2083761A (en) * | 1980-09-11 | 1982-03-31 | Medizin Labortechnik Veb K | A combination sorbent, dialyser |
CN2393549Y (en) * | 1999-10-29 | 2000-08-30 | 王占仁 | Disposable carbon kidney |
CN2780207Y (en) * | 2005-04-12 | 2006-05-17 | 浙江科锐生物科技有限公司 | Disposable active carbon blood perfusion device |
CN201211354Y (en) * | 2008-05-21 | 2009-03-25 | 珠海丽珠医用生物材料有限公司 | Disposable blood perfusion device |
CN201768206U (en) * | 2010-05-26 | 2011-03-23 | 重庆希尔康血液净化器材研发有限公司 | Hemoperfusion apparatus |
-
2010
- 2010-05-26 CN CN2010101831451A patent/CN101843932B/en active Active
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2083761A (en) * | 1980-09-11 | 1982-03-31 | Medizin Labortechnik Veb K | A combination sorbent, dialyser |
CN2393549Y (en) * | 1999-10-29 | 2000-08-30 | 王占仁 | Disposable carbon kidney |
CN2780207Y (en) * | 2005-04-12 | 2006-05-17 | 浙江科锐生物科技有限公司 | Disposable active carbon blood perfusion device |
CN201211354Y (en) * | 2008-05-21 | 2009-03-25 | 珠海丽珠医用生物材料有限公司 | Disposable blood perfusion device |
CN201768206U (en) * | 2010-05-26 | 2011-03-23 | 重庆希尔康血液净化器材研发有限公司 | Hemoperfusion apparatus |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102488933A (en) * | 2011-12-12 | 2012-06-13 | 重庆希尔康血液净化器材研发有限公司 | Blood perfusion device |
CN103845767A (en) * | 2012-12-03 | 2014-06-11 | 于杰 | Blood perfusion device for experimental animals |
CN110314259A (en) * | 2019-07-24 | 2019-10-11 | 广州康盛生物科技有限公司 | Perfusion device |
CN110448750A (en) * | 2019-07-26 | 2019-11-15 | 北京中科盛康科技有限公司 | A kind of blood perfusion device |
CN110448750B (en) * | 2019-07-26 | 2024-03-15 | 北京中科盛康科技有限公司 | Blood perfusion device |
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Publication number | Publication date |
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CN101843932B (en) | 2012-06-27 |
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Denomination of invention: Blood perfusion device Effective date of registration: 20231214 Granted publication date: 20120627 Pledgee: Societe Generale Limited by Share Ltd. Chongqing branch Pledgor: CHONGQING XIERKANG BLOOD PURIFICATION EQUIPMENT RESEARCH DEVELOPMENT CO.,LTD. Registration number: Y2023500000103 |
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