Background technology
In recent years, develop rapidly and popularize in China take the blood purification therapy of extracorporeal circulation as the basis.Wherein, because severe liver diseases patient enormous amount, and the outstanding curative effect of blood plasma adsorbing therapy aspect the heavy hepatopath's symptom of alleviation, the demand of disposable use bilirubin blood plasma adsorption column constantly increases.Make visible component and the separating plasma of blood by extracorporeal circulation, blood plasma is introduced disposable use bilirubin blood plasma adsorption column and is carried out plasma perfusion treatment after will separating, utilize super porous anion resin in the adsorption column can optionally remove bilirubin in the blood plasma, reach the purpose that purifies the blood.
Disposable use bilirubin blood plasma adsorption column is in the blood purification process, be connected in the outer blood circulation loop of lead body, blood is through visible component and the separating plasma of blood plasma separator with blood, with the bilirubin adsorption in the blood plasma, the blood plasma after the absorption converges with the blood effective ingredient that separates before this and enters body-internal-circulation again plasma flow when disposable use bilirubin blood plasma adsorption column.Disposable use bilirubin blood plasma adsorption column is as aseptic medical equipment, enforcement along with " aseptic medical equipment quality of production management regulation ", medicine prison department of country will be more strict to the supervision of Related product, so the sterilization of disposable use bilirubin blood plasma adsorption column, sealed type storage, transportation after particularly sterilizing are extremely important.In the process of transportation, if disposable use bilirubin blood plasma adsorption column is poorly sealed, can cause air to enter the resin anion (R.A.) that pollutes filling in the disposable use bilirubin blood plasma adsorption column, gnotobasis is destroyed, cause and to be used for clinical trial, or because of the not carefully clinically misuse of clinical preoperation inspection, and cause most probably malpractice, bring the risk for the treatment of to the patient.
At present, common disposable use bilirubin blood plasma adsorption column all is comprised of middle cylinder, filter screen, end cap, locking nut, block, rubber cushion and resin anion (R.A.) adsorbent etc., in assembling, filter screen is contained in the middle cylinder, end cap seals middle cylinder, fill a packing ring between end cap and the middle cylinder, by locking nut locking, the blood mouth of end cap central authorities is by the rubber cushion press seal in block and the block between end cap and the middle cylinder.Filter screen generally is to be welded by filter membrane and an annular brace sheet, in clinical practice, in case the adsorption column internal pressure is excessive, owing to do not support in the middle of the filter screen, cause easily filter screen to break, cause the absorption in the adsorption column to enter the blood circulation loop, in a single day the adsorbent of seepage enters in the patient body, will cause immeasurable consequence.Entire terminal cover (containing gland) is in case after tightening sealing, when high pressure steam sterilization, because the effect of temperature and pressure causes distortion easily, also can't seal fully when again tightening after the sterilization simultaneously.Also the someone attempts eddy current or ultra-sonic welded are carried out in needs sealing place, exists equally the very difficult assurance in position of vortex induction circle and bonding wire concentric, and circumference temp is difficult to consistent, and welding effect is difficult to assurance, the many problems of waste product behind the welding fabrication.Although and employing ultra-sonic welded end cap (containing gland) good sealing effect causes cap sealed place pressure excessive deformation easily when high pressure steam sterilization, poorly sealed real problem after the sterilization.
The utility model content
Technical problem to be solved in the utility model is to provide a kind of filter screen safety, the disposable use bilirubin blood plasma adsorption column of good sealing effect.
The technical solution of the utility model is as follows: a kind of disposable use bilirubin blood plasma adsorption column, comprise cylinder, filter screen, sealing ring, gland, end cap, block and adsorbent, its key is: there are screw thread and end cap fitted seal in cylinder two outer ends, cylinder has ring-shaped step in the two ends, filter screen is formed through sweat soldering by support chip and filter membrane, be embedded in the ring-shaped step in the cylinder two ends, 8 class round rectangle passages evenly distribute on the support chip of described filter screen, consist of filter screen without flange one side and filter membrane sweat soldering, have boss one side and gland that sealing ring one side is housed and cooperate press seal.Between the filter screen of two ends adsorbent is housed, and is compressed by the gland that sealing ring is equipped with in the inboard, described gland middle part is arc and middlely is conducive to plasma flow and passes through with the blood plasma passage that the periphery is horizontal annular, during assembling by the pressure head press seal of end cap; Gland one side is with flange, be used for fixed seal ring and with the filter screen press seal, the gland opposite side is the blood vessel joint, in screw thread is arranged, during assembling with the block fitted seal.Through screwing the end cap at cylinder two ends, by the annular pressure head compression gland seal of end cap inboard, described end cap is hollow structure, and inner structure is the end cap pressure head, and there is screw thread the external structure inboard, and external structure outside lower edge is boss structure.
Inboard, above-mentioned cylinder two ends is provided with reinforcement, and in order to gaining in strength, the ring-shaped step of inboard, described two ends is in order to embed and fixing filter screen, and the outside is provided with flange, in order to isolated sealing.
The support chip of above-mentioned filter screen is that the filter membrane on the filter screen provides support, 8 class round rectangle passages on it channel of blood flow is provided, sweat soldering guarantees that support chip and filter membrane form firmly integrated filter screen, not only guaranteed blood flow usually but also can guarantee filter membrane rupture of membranes not when bearing larger pressure.
Be evagination arcuate structure and with the blood plasma path, the periphery is the horizontal annular structure in the middle of on the above-mentioned gland, during assembling by the pressure head press seal of end cap.The inboard arcuate structure of gland and horizontal annular structure excessively have annular boss in the place, are used for fixed seal ring; Gland outer side center blood plasma path place is provided with the blood vessel joint, in screw thread is arranged, during assembling with the block fitted seal.
Above-mentioned end cap is hollow structure, inner structure is the end cap pressure head, compress gland seal during assembling, there is screw thread the external structure inboard, the threaded engagement sealing of during assembling and cylinder two ends, outside lower edge is boss structure, can anti-skiddingly conveniently tighten and open, and can increase the attractive in appearance of disposable use bilirubin blood plasma adsorption column simultaneously.
Even 12 boss (5e) that distribute on the boss of above-mentioned external structure outside lower edge, boss can be smooth small boss structure.
The split-type design of above-mentioned gland and end cap can guarantee to seal compacting, can guarantee again to be out of shape in the high pressure steam sterilization process the rear good seal of guaranteeing to sterilize.
Above-mentioned adsorbent is to the selective adsorbing anionic ion exchange resin of bilirubin.
Disposable use bilirubin blood plasma adsorption column of the present utility model, comprise cylinder (1), filter screen (2), sealing ring (3), gland (4), end cap (5), block (6) and adsorbent (7), it is characterized in that: there are screw thread (1a) and end cap (5) fitted seal in described cylinder (1) two outer end, be provided with ring-shaped step (1b) in the cylinder two ends, described filter screen (2) is formed through sweat soldering by support chip and filter membrane, be embedded in the ring-shaped step (1b) in the cylinder two ends, adsorbent (7) is housed between the filter screen of two ends, and compressed by the gland (4) that sealing ring (3) are equipped with in the inboard, and inboard annular pressure head (4c) press seal of the end cap through being tightened on the cylinder two ends (5), described gland (4) is upper with blood vessel joint (4b), and block (6) sealing is housed on it.
Ring-shaped step (1b) is arranged in the cylinder two ends of adsorption column, and the outside is provided with flange (1c).Upper 8 the class round rectangles (2A-a) that evenly distribute of the support chip (2A) of the filter screen of adsorption column (2) are as the blood plasma passage, consist of filter screen without boss one side and filter membrane sweat soldering, have the boss (4d) that boss (2A-b) side and gland (4) are equipped with sealing ring (3) one sides to cooperate press seal.Its gland (5) middle part is outer convex (4a) structure and middle with blood vessel joint (4b), in the blood vessel joint screw thread is arranged, during assembling and block (6) fitted seal; The periphery is horizontal annular (4c), during assembling by annular pressure head (5c) press seal of end cap (5); The gland opposite side has flange (4d).The end cap of adsorption column (5) is hollow (5a) structure, and inner structure is end cap annular pressure head (5c), and there is screw thread (5d) external structure (5b) inboard; External structure outside lower edge is boss structure (5e).The external structure inside thread of above-mentioned end cap and the sealing of cylinder two ends threaded engagement, 12 boss (5e) evenly distribute on the boss of the external structure outside lower edge of end cap.
Beneficial effect: the strainer filtering film with support chip of the present utility model is difficult for broken, safe; Can't seal after distortion caused sterilization when the separation design of gland and end cap was conducive to prevent high pressure steam sterilization, it is tight that the design of the filter screen between gland and the filter and end cap pressure head and block guarantees to seal disposable bilirubin adsorption column sealing; The convenient processing of end cap pressure head hollow design, molding, cost is saved in weight reduction.
The specific embodiment
The utility model is described in further detail below in conjunction with drawings and Examples:
Such as Fig. 1, shown in Figure 2, a kind of disposable use bilirubin blood plasma adsorption column, comprise cylinder (1), filter screen (2), sealing ring (3), gland (4), end cap (5), block (6) and adsorbent (7), there are screw thread (1a) and end cap (5) fitted seal in described cylinder (1) two outer end, be provided with ring-shaped step (1b) in the cylinder two ends, filter screen (2) is formed through sweat soldering by support chip (2a) and filter membrane, be embedded in the ring-shaped step (1b) in the cylinder two ends, upper 8 class round rectangle passages (2A-a) (see figure 2) that evenly distributes of the support chip (2A) of described filter screen (2), consist of filter screen without boss (2A-b) side and filter membrane sweat soldering, have boss one side and gland (4) that sealing ring (3) one sides are housed and cooperate press seal.Adsorbent (7) is housed between the filter screen of two ends.The resin anion (R.A.) of described adsorbent (7) for bilirubin is had the selective absorption performance.Described gland (4) middle part is that male type arc (4a) and centre are provided with blood circuit joint (4b), and arcuate structure is conducive to plasma flow to be passed through, and in the blood vessel joint screw thread is arranged, during assembling and block (6) fitted seal; The periphery is horizontal annular (4c), during assembling by annular pressure head (5c) press seal of end cap (5); The gland opposite side is with flange (4d), be used for fixed seal ring (3) and with filter screen (2) press seal.Described end cap (5) is hollow (5a) structure, and inner structure is end cap annular pressure head (5c), and there is screw thread (5d) external structure (5b) inboard.External structure outside lower edge is boss structure.Described external structure inside thread and the sealing of cylinder two ends threaded engagement.12 smooth small boss (5e) evenly distribute on the boss of described external structure outside lower edge.
Although below by reference to the accompanying drawings preferred embodiment of the present utility model is described; but this utility model is not limited to the above-mentioned specific embodiment; the above-mentioned specific embodiment only is schematic rather than determinate; those skilled in the art is under enlightenment of the present utility model; under the prerequisite of this utility model aim and claim; can make and represent that such conversion is all within protection domain of the present utility model like the multiple types.