CN101842120A - 造影剂 - Google Patents

造影剂 Download PDF

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Publication number
CN101842120A
CN101842120A CN200880114820A CN200880114820A CN101842120A CN 101842120 A CN101842120 A CN 101842120A CN 200880114820 A CN200880114820 A CN 200880114820A CN 200880114820 A CN200880114820 A CN 200880114820A CN 101842120 A CN101842120 A CN 101842120A
Authority
CN
China
Prior art keywords
bis
triiodo
compound
dihydroxy
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN200880114820A
Other languages
English (en)
Chinese (zh)
Inventor
D·G·温
I·M·纽因顿
H·J·瓦德斯沃思
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
GE Healthcare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare AS filed Critical GE Healthcare AS
Publication of CN101842120A publication Critical patent/CN101842120A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN200880114820A 2007-10-30 2008-10-29 造影剂 Pending CN101842120A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20075474 2007-10-30
NO20075474 2007-10-30
PCT/EP2008/064632 WO2009056555A1 (en) 2007-10-30 2008-10-29 Contrast agents

Publications (1)

Publication Number Publication Date
CN101842120A true CN101842120A (zh) 2010-09-22

Family

ID=40201831

Family Applications (1)

Application Number Title Priority Date Filing Date
CN200880114820A Pending CN101842120A (zh) 2007-10-30 2008-10-29 造影剂

Country Status (5)

Country Link
US (1) US8551449B2 (https=)
EP (1) EP2203190A1 (https=)
JP (1) JP2011500770A (https=)
CN (1) CN101842120A (https=)
WO (1) WO2009056555A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105001114A (zh) * 2014-04-18 2015-10-28 沈阳中海生物技术开发有限公司 制备碘普罗胺的新方法
CN105017063A (zh) * 2014-04-18 2015-11-04 沈阳中海生物技术开发有限公司 5-氨基-2,4,6-三碘间苯二甲酸衍生物及其盐、水合物或溶剂化物
CN110291125A (zh) * 2016-12-02 2019-09-27 得克萨斯农业及机械体系综合大学 具有增加的x-射线可视化的化学改性的形状记忆聚合物栓塞泡沫
CN116813495A (zh) * 2023-06-16 2023-09-29 上海慧聚药业有限公司 合成碘克沙醇

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2628517C2 (de) * 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1245853B (it) * 1990-11-16 1994-10-25 Bracco Spa 1,3-bis(3-(mono o poliidrossi)acilamino-5-(mono o poliidrossi-alchil) aminocarbonil-2,4,6-triiodo-benzoil-amino)-idrossi- o idrossi-alchil- propani, loro metodo di preparazione e mezzi di contrasto roentgenografici che li contengono
GB9419206D0 (en) * 1994-09-23 1994-11-09 Nycomed Innovation Ab Contrast media
PT1435935E (pt) * 2001-10-12 2009-12-29 Lasser Family Partnership L P Meios de contraste de raios-x concentrados podem actuar como antigénios universais e podem inibir ou prevenir reacções alérgicas

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105001114A (zh) * 2014-04-18 2015-10-28 沈阳中海生物技术开发有限公司 制备碘普罗胺的新方法
CN105017063A (zh) * 2014-04-18 2015-11-04 沈阳中海生物技术开发有限公司 5-氨基-2,4,6-三碘间苯二甲酸衍生物及其盐、水合物或溶剂化物
CN105017063B (zh) * 2014-04-18 2018-11-20 沈阳中海生物技术开发有限公司 5-氨基-2,4,6-三碘间苯二甲酸衍生物及其盐、水合物或溶剂化物
CN110291125A (zh) * 2016-12-02 2019-09-27 得克萨斯农业及机械体系综合大学 具有增加的x-射线可视化的化学改性的形状记忆聚合物栓塞泡沫
CN110291125B (zh) * 2016-12-02 2022-04-19 得克萨斯农业及机械体系综合大学 具有增加的x-射线可视化的化学改性的形状记忆聚合物栓塞泡沫
US11407851B2 (en) 2016-12-02 2022-08-09 The Texas A&M University System Chemically modified shape memory polymer embolic foams with increased X-ray visualization
CN116813495A (zh) * 2023-06-16 2023-09-29 上海慧聚药业有限公司 合成碘克沙醇

Also Published As

Publication number Publication date
EP2203190A1 (en) 2010-07-07
US8551449B2 (en) 2013-10-08
JP2011500770A (ja) 2011-01-06
US20100260685A1 (en) 2010-10-14
WO2009056555A1 (en) 2009-05-07

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20100922