CN101829038B - Winkle-removing Chinese medicament facial mask and preparation method thereof - Google Patents
Winkle-removing Chinese medicament facial mask and preparation method thereof Download PDFInfo
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Abstract
The invention provides a winkle-removing Chinese medicament facial mask. The active ingredient of the facial mask is a water extract of 10 to 40 percent of Chinese angelica, 20 to 70 percent of dwarf lilyturf tuber and 15 to 50 percent of common bletilla pseudobulb, wherein the dwarf lilyturf tuber can nourish yin and the lung, tonify stomach and invite body fluid, and it is recorded in Compendium of Materia Medica that the dwarf lilyturf tuber has the effects of 'facial beautification and skin care' and is used as a monarch medicament; the Chinese angelica has the effect of nourishing skin, lustring the skin and generating skin; the common bletilla pseudobulb restrains generated skin, nourishes the skin and prevents the skin from becoming rough and rhagadiform and is used as a ministerial medicament together with the Chinese angelica; the Chinese angelica, which can enrich and activate blood, is also used as an adjuvant medicament; and the three medicaments cooperates to nourish yin and skin, activate and enrich blood, restrain skin and remove winkles. The facial mask of the invention may also contain skin nutrients such as transparent hyaluronic acid and collagen, which can further improve the skin-care effect of the facial mask of the invention.
Description
Technical field
The present invention relates to cosmetic field, be specifically related to a kind of facial film of Chinese medicine compound extract preparation.
Background technology
Facial film is a kind of cosmetics and skincare product that applies on the face, can play the effect of cleaning, fitness and protection face.Along with the effect that traditional Chinese medicine beauty treatment is improved looks is in modern times admitted by increasing people, the Chinese medicine facial film arises at the historic moment as the ideal skin care item of a kind of skin nursing, and has obtained liking of people with its hyposensitivity and low side effect.Increasing moisture of skin is the basis of beauty and skin care, and the skin that dries out is can be dry coarse, form microgroove, pigmentation, causes many skin problems.Be Liliaceae Ophiopogon perennial evergreen herbaceous plant Radix Ophiopogonis; It has the effect of " U.S. color is pleased skin " the Compendium of Materia Medica record, often is used for beauty and skin care by people; Facial film Radix Ophiopogonis like folklore is processed by Radix Ophiopogonis, Radix Asparagi and Radix Pseudostellariae, has the effect of preserving moisture.Commercial goods snow is full of the plant mask of whitening for another example, and its main component is a Radix Ophiopogonis extract, peach extract, Flos Carthami extract, Radix Asparagi extract, Radix Angelicae Sinensis extract, cucurbitaceous plant, green tea extract, arbutin, the effect that having preserves moisture whitens.These prescriptions are mainly started with preserving moisture from antioxidation, have certain whitening skin and preserving moisture effect, but a little less than the effect of wrinkle removal.
Summary of the invention
The technical problem that the present invention will solve provides a kind of Chinese medicine facial film with wrinkle removal effect.
The technical scheme that the present invention addresses the above problem is:
A kind of Chinese medicine facial film of wrinkle removal, this facial film is made up of effective components of Chinese medicinal and facial film field acceptable auxiliary, it is characterized in that said effective ingredient comprises that concentration is the Chinese medicine extraction liquid of 0.2～2g medical material/mL; Described Chinese medicine extraction liquid is obtained by the Chinese medicine water decocting method extraction of following weight proportion: Radix Angelicae Sinensis 10%～40%, Radix Ophiopogonis 20%～70%, Pseudobulbus Bletillae (Rhizoma Bletillae) 15%～50%; Every facial film is loaded with described Chinese medicine extraction liquid 80mL.
In the facial film of the present invention, described Chinese medicine extraction liquid is obtained by the Chinese medicine water decocting method extraction of following weight proportion: Radix Angelicae Sinensis 20%～30%, Radix Ophiopogonis 40%～50%, Pseudobulbus Bletillae (Rhizoma Bletillae) 25%～35%.
In the facial film of the present invention; Described effective ingredient also can comprise and occupies the skin-nourishing thing of imitating composition 0.5～5.7% (W/W) cosmetic result with further raising facial film of the present invention; Described skin-nourishing thing is selected from Semen Tritici aestivi germ oil, a kind of or two or more in hyaluronic acid and the collagen protein.
Chinese medicine extraction liquid in the facial film according to the invention is prepared by following method:
(1) get Radix Ophiopogonis, Radix Angelicae Sinensis and Pseudobulbus Bletillae (Rhizoma Bletillae), decocte with water twice adds 6～10 times for the first time and decocted 1.5～3 hours, adds 6～10 times for the second time and decocts 1.5～3 hours; Merge decocting liquid twice, filter, be concentrated into 0.2～2g medical material/mL, cold preservation was left standstill 10～24 hours, filtered, and adding water adjustment filter liquor concentration is 0.2～2g medical material/mL, gets Chinese medicine extraction liquid;
(2) carry the ratio of the said Chinese medicine extraction liquid of 80mL in every facial film, get Chinese medicine extraction liquid and the facial film adjuvant is processed facial film by conventional method;
In the above-mentioned steps, described facial film adjuvant comprises dispersant and carrier, wherein,
Described dispersant is selected from propylene glycol, glycerin or ethanol, preferred propylene glycol or glycerin;
Said carrier is gel-type vehicle or non-woven fabrics, and wherein, described gel-type vehicle is one or both in soybean fiber, arabic gum, carrageenan, Konjac glucomannan and the gelatin.
In the method for preparing of facial film of the present invention, described adjuvant also can comprise one or both in the following adjuvant:
1. antiseptic:, can be selected from chlorobutanol, benzyl alcohol, phenethanol, methyl hydroxybenzoate, ethyl hydroxybenzoate and the propylparaben one or both, preferably ethyl hydroxybenzoate or propylparaben to prolong the shelf-life of facial film of the present invention.
2. solubilizing agent: optional to increase the dissolving of skin-nourishing thing from tween 80, SP-115A (Xin Pu company) or 1264 emulsifying agents (Xin Pu company).
When facial film of the present invention selects for use gel-type vehicle to be carrier, promptly be the quartzy facial film that is commonly called as, concrete method for making is following:
(1) scattered dispersant and gel-type vehicle mixture added in the said Chinese medicine extraction liquid by proportioning, be heated to 80～90 ℃ and fully stirred 15 minutes, transfer to pH5.5～6.5 with the pH regulator agent;
(2) film forming (promptly processing facial film), packing, sterilization;
Wherein said pH regulator agent is hydrochloric acid, citric acid and phosphate buffer solution.
If the effective ingredient in the said quartzy facial film also comprises the skin-nourishing thing, then step (2) should be: add the skin-nourishing thing after being cooled to 50 ℃, mixing, film forming, packing, sterilization.
If said quartzy facial film also contains adjuvants such as antiseptic or solubilizing agent, then when the preparation facial film, said adjuvant and gel-type vehicle are disperseed with dispersant, join in the Chinese medicine extraction liquid again.
When facial film of the present invention selects for use non-woven fabrics to be carrier, promptly be the non-woven fabrics facial film that is commonly called as, concrete method for making is following: dispersant is joined in step (1) the gained Chinese medicine extraction liquid, fully mix, stir, the non-woven fabrics that high-temperature sterilization is good absorbs, packing, radiation sterilization.
If the effective ingredient in the said non-woven fabrics facial film also comprises the skin-nourishing thing, then the skin-nourishing thing prepares in the process at facial film and joins Chinese medicine extraction liquid with dispersant, and stirring gets final product.
If said non-woven fabrics facial film also contains adjuvants such as antiseptic or solubilizing agent, then when the preparation facial film, said adjuvant is disperseed with dispersant, join in the Chinese medicine extraction liquid again.
Facial film according to the invention as active component, can play skin moistening wrinkle removal effect with the effective ingredient of Radix Ophiopogonis, Radix Angelicae Sinensis and Pseudobulbus Bletillae (Rhizoma Bletillae).
The traditional Chinese medical science is thought lung governing skin and hair, and lack of lung-YIN then fur lacks body fluid and moistens fosterly, is prone to produce wrinkle, pachylosis, and complexion is black dull withered and matt." element asks that the five internal organs generate ": " the tissue connected with the lung being skin, its flourish hair also." in the facial film of the present invention, Radix Ophiopogonis can nourishing YIN and moistening the lung, reinforcing stomach reg fluid, it has the effect of " U.S. color is pleased skin " the Compendium of Materia Medica record, is monarch drug.Zhang Xichun says: " cool in nature, body fluid is dense lubricious for Radix Asparagi, the little suffering of sweet in the mouth, kind promoting the production of body fluid to quench thirst.The property of Tianjin dope cunning, can tonneau two just, the circulation blood vessels, fluent meridians are though be the article of YIN nourishing, the real ability tonification edema caused by disorder of QI of holding concurrently." the Radix Asparagi YIN nourishing and the production of body fluid promoting moisturizes, and makes body fluid be popular in the whole body, moist skin.The Radix Angelicae Sinensis skin moistening, skin care, granulation promoting; Pseudobulbus Bletillae (Rhizoma Bletillae) convergence granulation promoting, skin care prevents pachylosis, chaps, and is ministerial drug altogether; The Radix Angelicae Sinensis blood circulation promoting and enriching, holding concurrently is adjuvant drug.Radix Ophiopogonis, the matter profit can provide a large amount of body fluid to moisten foster fur, and Radix Angelicae Sinensis, Pseudobulbus Bletillae (Rhizoma Bletillae) also can play the skin moistening effect.Radix Angelicae Sinensis can also be invigorated blood circulation, and makes meridians unobstructed, thereby makes nutrient substance can moisten foster skin better, and helps the drainage of waste matter, makes the smooth no speckle of skin.Three medicines are made a concerted effort, and play the merit of YIN nourishing skin moistening, blood circulation promoting and enriching, wrinkle removal convergence altogether.
In order to understand the present invention better, will further specify the technique effect that the present invention has through clinical experiment report below.
1, patient data: select place, canthus, forehead, buccal portion, mouthful all places or cervical region wrinkle patient 90 examples to be arranged, each 45 example of men and women, 30～45 years old age.Be divided into three groups at random: treatment group (Chinese medicine extraction liquid adds the skin nutrient) 30 examples, each 15 example of men and women, 38 ± 7 years old age; Matched group is (carrageenan adds water) 30 examples 1., each 15 example of men and women, 36 ± 8 years old age; Matched group is (Chinese medicine extraction liquid 2.; Do not add the skin nutrient) 30 examples, each 15 example of men and women, 37 ± 8 years old.
Respectively organize patient's sex, age, skin symptom integration before the treatment there are no significant difference (P＞0.05), have comparability.
2, experiment material:
(1) treatment group of the present invention:
The treatment group: contain the skin-nourishing thing in the effective ingredient of used facial film, press embodiment 1 preparation, every weight is 80 grams, specification 10*15cm.
(2) the matched group facial film prepares by following method:
Matched group is 1.:
Prescription: carrageenan 11g, ethyl hydroxybenzoate 2g processes 1000g
Method for making: water adds carrageenan after being heated to 80-90 ℃, and ethyl hydroxybenzoate fully stirred 15 minutes, regulates pH value to 5.5-6.5, film forming, packing, sterilization.
Matched group is 2.: do not contain the skin-nourishing thing in the effective ingredient of used facial film, used facial film is pressed embodiment 17 preparations, and every weight is 80 grams, specification 10*15cm.
3, experimental technique:
The treatment group: the patient lies on the back, and after washing one's face, spreads on face with facial film of the present invention, flush away behind about 15min.3 times weekly, be 2 weeks the course of treatment.
Matched group: the patient lies on the back, and after washing one's face, spreads on face, flush away behind about 15min with matched group facial film (not drug ingredients) and embodiment 17 facial films 1..3 times weekly, be 2 weeks the course of treatment.
4, clinical symptoms standards of grading: there is shallow thin crows-feet at the place, canthus; The plain wrinkle person of forehead respectively is designated as 2 fens; Place, canthus, forehead, the thick tail stricture of vagina person of buccal portion respectively are designated as 4 fens, and place, canthus, forehead, buccal portion, mouthful all places and cervical region have obvious wrinkle person respectively to be designated as 6 fens.Microgroove shoals and is designated as 1 fen, and place, canthus, forehead, the thick tail stricture of vagina of buccal portion shoal and be designated as 2 fens, place, canthus, forehead, buccal portion, mouthful week the place and cervical region have obvious wrinkle to shoal to be designated as 3 fens, wrinkle disappears and is designated as 0 fen.
5, efficacy assessment standard:
By formula earlier---score value * 100% calculates the improvement rate before clinical symptoms integration score value improvement rate=(symptom integral score value before the treatment-treatment back symptom integral score value)/treatment, adopts criterion evaluation curative effect then.
Produce effects: symptom integral score value improvement rate >=70%;
Effectively: symptom integral score value improvement rate >=50%;
Invalid: symptom does not see that obvious improvement or counter sees deterioration, symptom integral score value improvement rate＜50%.
6, statistical procedures: total data adopts SPSS 13.0 statistics softwares to carry out statistical analysis, and measurement data is with mean ± standard deviation (x ± s) expression.Symptom score more all adopted the t check before and after two groups of experimenters treated, and two groups of experimenter's clinical efficacies relatively adopt X
2Check.
7, result of the test
Table 1 is relatively seen in the clinical symptoms scoring before and after treatment group and the treatment of control group, and curative effect is relatively seen table 2 before and after treatment group and the treatment of control group, can know from table 2; Facial film wrinkle removal total effective rate of the present invention is up to 83%, and observes through the treatment group and not have the heating of the skin of discovery, flushing; Edema, untoward reaction such as pruritus.
Clinical symptoms scoring before and after table 1 treatment group and the treatment of control group
| Group | n | Before the treatment | After the treatment | Difference |
| The treatment group | 30 | 11.87±1.28 | 4.70±1.24 | 7.17±1.69 |
| Matched group 1. | 30 | 11.67±1.06 | 7.80±0.92 | 3.87±1.20 |
| Matched group 2. | 30 | 11.80±1.42 | 4.83±1.20 | 6.97±2.09 |
Table 2 treatment group and matched group curative effect are relatively
| Group | Case load | Produce effects | Effectively | Invalid | Total effective rate/% |
| The treatment group | 30 | 6 | 19 | 5 | 83.3 |
| Matched group 1. | 30 | 0 | 2 | 28 | 6.7 |
| Matched group 2. | 30 | 4 | 19 | 7 | 76.7 |
1. treatment group and matched group compare, and the evident in efficacy of medicine explained in P＜0.01.
2. treatment group and matched group compare P＞0.05; What main therapeutical effect had been described is Chinese medicine extraction liquid; But the difference of integration can be found out from the treatment front and back; Chinese medicine extraction liquid adds skin-nourishing thing group (i.e. treatment group) and does not add skin nutrient group (be matched group 2.) and relatively, can play wrinkle removal effect preferably.
The specific embodiment
Among the following embodiment 1～17, the recipe quantity of each embodiment is the recipe quantity of 12.5 facial films.
Embodiment 1
Prescription:
Radix Angelicae Sinensis 118g, Radix Ophiopogonis 211g, Pseudobulbus Bletillae (Rhizoma Bletillae) 141g;
Carrageenan 11g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.5g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.5: 1 medicinal liquid of written treaty; Filter, 0.5: 1 medicinal liquid (0.5g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).Because hyaluronic acid than indissoluble, is difficult to homodisperse with medicinal liquid is directly mixed mutually, obtains the hyalomitome acid solution so earlier hyaluronic acid is dissolved in the water, and then mixes with medicinal liquid.
Embodiment 2
Prescription:
Radix Angelicae Sinensis 180g, Radix Ophiopogonis 120g, Pseudobulbus Bletillae (Rhizoma Bletillae) 300g;
Carrageenan 11g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.63g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.63: 1 medicinal liquid of written treaty; Filter, 0.63: 1 medicinal liquid (0.63g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 3
Prescription:
Radix Ophiopogonis 320g, Radix Angelicae Sinensis 360g, Pseudobulbus Bletillae (Rhizoma Bletillae) 120g;
Carrageenan 11g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.85g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.85: 1 medicinal liquid of written treaty; Filter, 0.85: 1 medicinal liquid (0.85g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 4
Prescription:
Radix Ophiopogonis 141g, Radix Angelicae Sinensis 564g, Pseudobulbus Bletillae (Rhizoma Bletillae) 705g;
Carrageenan 11g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 8 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 1.5g medical material/ml), cold preservation was left standstill 24 hours to concentrate 1.5: 1 medicinal liquids of written treaty; Filter, 1.5: 1 medicinal liquid (1.5g medical materials/ml), get Chinese medicine extraction liquid are filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 5
Prescription:
Radix Ophiopogonis 960g, Radix Angelicae Sinensis 320g, Pseudobulbus Bletillae (Rhizoma Bletillae) 600g;
Carrageenan 11g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 10 times of water gagings for the first time; For the second time add 10 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 2g medical material/ml), cold preservation was left standstill 24 hours to concentrate 2: 1 medicinal liquids of written treaty; Filter, 2: 1 medicinal liquid (2g medical materials/ml), get Chinese medicine extraction liquid are filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 6
Prescription:
Radix Ophiopogonis 120g, Radix Angelicae Sinensis 20g, Pseudobulbus Bletillae (Rhizoma Bletillae) 60g;
Soybean fiber 11g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.2g medical material/ml), cold preservation was left standstill 24 hours to be condensed into 0.2: 1 medicinal liquid; Filter, 0.2: 1 medicinal liquid (0.2g medical material/ml), get Chinese medicine extraction liquid is filtrated in the moisturizing adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 7
Prescription:
Radix Angelicae Sinensis 94g, Radix Ophiopogonis 211g, Pseudobulbus Bletillae (Rhizoma Bletillae) 165g;
Carrageenan 13g, propylene glycol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 1g propylparaben 1g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 6 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.5g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.5: 1 medicinal liquid of written treaty; Filter, 0.5: 1 medicinal liquid (0.5g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, to get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, propylparaben is heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 8
Prescription:
Radix Angelicae Sinensis 141g, Radix Ophiopogonis 211g, Pseudobulbus Bletillae (Rhizoma Bletillae) 118g;
Carrageenan 13g, ethanol 50g, hyaluronic acid 0.1g, collagen protein 5g, ethyl hydroxybenzoate 1g propylparaben 1g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.5g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.5: 1 medicinal liquid of written treaty; Filter, 0.5: 1 medicinal liquid (0.5g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, to get Chinese medicine extraction liquid and add scattered ethanol, carrageenan and ethyl hydroxybenzoate, propylparaben is heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 9
Prescription:
Radix Angelicae Sinensis 47g, Radix Ophiopogonis 329g, Pseudobulbus Bletillae (Rhizoma Bletillae) 94g;
Carrageenan 13g, ethanol 50g, hyaluronic acid 0.25g, collagen protein 10g, ethyl hydroxybenzoate 1g, benzyl alcohol 5g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.53g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.53: 1 medicinal liquid of written treaty; Filter, 0.53: 1 medicinal liquid (0.53g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get scattered ethanol, carrageenan and ethyl hydroxybenzoate, the benzyl alcohol of Chinese medicine extraction liquid adding and be heated to 80-90 ℃ of abundant the stirring 15 minutes, regulate pH value to 5.5-6.5; Be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing makes dissolving fully; Film forming; Packing, sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 10
Prescription:
Radix Angelicae Sinensis 94g, Radix Ophiopogonis 235g, Pseudobulbus Bletillae (Rhizoma Bletillae) 141g;
Carrageenan 13g, glycerin 50g, hyaluronic acid 0.25g, collagen protein 10g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.53g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.53: 1 medicinal liquid of written treaty; Filter, 0.53: 1 medicinal liquid (0.53g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get scattered glycerin, carrageenan and the ethyl hydroxybenzoate of Chinese medicine extraction liquid adding and be heated to 80-90 ℃ of abundant the stirring 15 minutes, regulate pH value to 5.5-6.5; Be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing makes dissolving fully; Film forming; Packing, sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 11
Prescription:
Radix Angelicae Sinensis 80g, Radix Ophiopogonis 240g, Pseudobulbus Bletillae (Rhizoma Bletillae) 150g;
Carrageenan 10g, arabic gum 3g, propylene glycol 50g, hyaluronic acid 0.25g, collagen protein 10g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.53g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.53: 1 medicinal liquid of written treaty; Filter, 0.53: 1 medicinal liquid (0.53g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, to get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and arabic gum, ethyl hydroxybenzoate is heated to 80-90 ℃ and fully stirred 15 minutes; Regulate pH value to 5.5-6.5, be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 12
Prescription:
Radix Angelicae Sinensis 80g, Radix Ophiopogonis 240g, Pseudobulbus Bletillae (Rhizoma Bletillae) 150g;
Carrageenan 11g, propylene glycol 50g, hyaluronic acid 0.25g, collagen protein 50g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 10 times of water gagings for the first time; For the second time add 8 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.56g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.56: 1 medicinal liquid of written treaty; Filter, 0.56: 1 medicinal liquid (0.56g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get scattered propylene glycol, carrageenan and the ethyl hydroxybenzoate of Chinese medicine extraction liquid adding and be heated to 80-90 ℃ of abundant the stirring 15 minutes, regulate pH value to 5.5-6.5; Be cooled to about 50 ℃ and add 0.5% hyalomitome acid solution and collagen protein, Magnesium L-Asacorbic Acid 2-O-Phosphate, mixing; Make dissolving fully, film forming, packing; Sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 13
Prescription:
Radix Angelicae Sinensis 229g, Radix Ophiopogonis 686g, Pseudobulbus Bletillae (Rhizoma Bletillae) 428g;
Hyaluronic acid 0.36g, collagen protein 18g, propylene glycol 180g.
Method for making: get Radix Codonopsis, the Radix Astragali and Poria, the decocte with water secondary adds 6 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 1.74g medical material/ml), cold preservation was left standstill 24 hours to concentrate 1.74: 1 medicinal liquids of written treaty; Filter, 1.74: 1 medicinal liquid (1.74g medical materials/ml), get Chinese medicine extraction liquid are filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, to get Chinese medicine extraction liquid and add with the scattered Oleum menthae of propylene glycol, 0.5% hyalomitome acid solution and collagen protein fully mixes, and stirs, and the non-woven fabrics that high-temperature sterilization is good absorbs, packing, and sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 14
Prescription:
Radix Angelicae Sinensis 150g, Radix Ophiopogonis 600g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g;
Hyaluronic acid 0.1g, collagen protein 5g, Semen Tritici aestivi germ oil 20g, propylene glycol 50g, 1264 emulsifying agents (Xin Pu company) 4g.
Method for making: get Radix Codonopsis, the Radix Astragali and Poria, the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 1.22g medical material/ml), cold preservation was left standstill 24 hours to concentrate 1.22: 1 medicinal liquids of written treaty; Filter, 1.22: 1 medicinal liquid (1.22g medical materials/ml), get Chinese medicine extraction liquid are filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add with 1264 scattered emulsifying agents of propylene glycol, Oleum menthae, Semen Tritici aestivi germ oil; 0.5% hyalomitome acid solution and collagen protein fully mixes, and stirs; The non-woven fabrics that high-temperature sterilization is good absorbs, packing, and radiation sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 15
Prescription:
Radix Angelicae Sinensis 150g, Radix Ophiopogonis 600g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g;
Hyaluronic acid 0.1g, collagen protein 5g, Semen Tritici aestivi germ oil 20g propylene glycol 50g, SP-115A (Xin Pu company) 4g.
Method for making: get Radix Codonopsis, the Radix Astragali and Poria, the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 1.22g medical material/ml), cold preservation was left standstill 24 hours to concentrate 1.22: 1 medicinal liquids of written treaty; Filter, 1.22: 1 medicinal liquid (1.22g medical materials/ml), get Chinese medicine extraction liquid are filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add with the scattered SP-115A of propylene glycol, Oleum menthae, Semen Tritici aestivi germ oil; 0.5% hyalomitome acid solution and collagen protein fully mixes, and stirs; The non-woven fabrics that high-temperature sterilization is good absorbs, packing, and radiation sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 16
Prescription:
Radix Angelicae Sinensis 150g, Radix Ophiopogonis 600g, Pseudobulbus Bletillae (Rhizoma Bletillae) 350g;
Hyaluronic acid 0.1g, collagen protein 5g, Semen Tritici aestivi germ oil 20g, propylene glycol 50g, tween 80 10g.
Method for making: get Radix Codonopsis, the Radix Astragali and Poria, the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 1.22g medical material/ml), cold preservation was left standstill 24 hours to concentrate 1.22: 1 medicinal liquids of written treaty; Filter, 1.22: 1 medicinal liquid (1.22g medical materials/ml), get Chinese medicine extraction liquid are filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add with the scattered tween 80 of propylene glycol, Oleum menthae, Semen Tritici aestivi germ oil; 0.5% hyalomitome acid solution and collagen protein fully mixes, and stirs; The non-woven fabrics that high-temperature sterilization is good absorbs, packing, and radiation sterilization promptly gets.
In the above-mentioned steps, described 0.5% hyalomitome acid solution is that concentration is the hyaluronic acid aqueous solution of 0.5% (w/w).
Embodiment 17
Prescription:
Radix Angelicae Sinensis 80g, Radix Ophiopogonis 240g, Pseudobulbus Bletillae (Rhizoma Bletillae) 150g;
Carrageenan 11g, propylene glycol 50g, ethyl hydroxybenzoate 2g.
Method for making:
Get Radix Angelicae Sinensis, Radix Ophiopogonis and Pseudobulbus Bletillae (Rhizoma Bletillae), the decocte with water secondary adds 8 times of water gagings for the first time; For the second time add 6 times of water gagings, each 3 hours, merge the secondary decocting liquid; Filter, (the 0.5g medical material/ml), cold preservation was left standstill 24 hours to concentrate 0.5: 1 medicinal liquid of written treaty; Filter, 0.5: 1 medicinal liquid (0.5g medical material/ml), get Chinese medicine extraction liquid is filtrated in adjustment; In the ratio that every facial film carries the 80mL Chinese medicine extraction liquid, get Chinese medicine extraction liquid and add scattered propylene glycol, carrageenan and ethyl hydroxybenzoate, be heated to 80-90 ℃ and fully stirred 15 minutes, regulate pH value to 5.5-6.5; Mixing makes dissolving fully, film forming; Packing, sterilization promptly gets.
Claims (9)
1. the Chinese medicine facial film of a wrinkle removal, this facial film is made up of effective components of Chinese medicinal and facial film field acceptable auxiliary, it is characterized in that said effective ingredient comprises the Chinese medicine extraction liquid of 0.2～2g medical material/mL; Described Chinese medicine extraction liquid is obtained by the Chinese medicine water decocting method extraction of following weight proportion: Radix Angelicae Sinensis 10%～40%, Radix Ophiopogonis 20%～70%, Pseudobulbus Bletillae (Rhizoma Bletillae) 15%～50%; Every facial film is loaded with described Chinese medicine extraction liquid 80mL.
2. facial film according to claim 1 is characterized in that described Chinese medicine extraction liquid is extracted by the Chinese medicine water decocting method of following weight proportion to obtain: Radix Angelicae Sinensis 20%～30%, Radix Ophiopogonis 40%～50%, Pseudobulbus Bletillae (Rhizoma Bletillae) 25%～35%.
3. facial film according to claim 1, it is characterized in that said effective ingredient also comprises occupies the skin-nourishing thing of imitating composition 0.5～5.7% (W/W), and described skin-nourishing thing is selected from Semen Tritici aestivi germ oil, a kind of or two or more in hyaluronic acid and the collagen protein.
4. the method for preparing of claim 1 or 2 said facial films, this method is made up of following steps:
(1) get Radix Ophiopogonis, Radix Angelicae Sinensis and Pseudobulbus Bletillae (Rhizoma Bletillae), decocte with water twice adds 6～10 times for the first time and decocted 1.5～3 hours, adds 6～10 times for the second time and decocts 1.5～3 hours; Merge decocting liquid twice, filter, be concentrated into 0.2～2g medical material/mL, cold preservation was left standstill 10～24 hours, filtered, and adding water adjustment filter liquor concentration is 0.2～2g medical material/mL, gets Chinese medicine extraction liquid;
(2) carry the ratio of the said Chinese medicine extraction liquid of 80mL in every facial film, get Chinese medicine extraction liquid, dispersant and carrier and process facial film by conventional method;
In the above-mentioned steps, described facial film adjuvant comprises dispersant and carrier, wherein,
Described dispersant is selected from propylene glycol, glycerin or ethanol;
Said carrier is gel-type vehicle or non-woven fabrics, and wherein, described gel-type vehicle is one or both in soybean fiber, arabic gum, carrageenan, Konjac glucomannan and the gelatin.
5. like the said method of claim 4, it is characterized in that described dispersant is propylene glycol or glycerin.
6. like the said method of claim 4, it is characterized in that said facial film adjuvant also comprises antiseptic, said antiseptic is one or both in chlorobutanol, benzyl alcohol, phenethanol, methyl hydroxybenzoate, ethyl hydroxybenzoate and the propylparaben.
7. like the said method of claim 6, it is characterized in that described antiseptic is ethyl hydroxybenzoate or propylparaben.
8. like the said method of claim 4, it is characterized in that said facial film adjuvant also comprises solubilizing agent, described solubilizing agent is a tween 80.
9. like the said method of claim 6, it is characterized in that said facial film adjuvant also comprises solubilizing agent, described solubilizing agent is a tween 80.
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| CN2010101796674A CN101829038B (en) | 2010-05-17 | 2010-05-17 | Winkle-removing Chinese medicament facial mask and preparation method thereof |
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| CN2010101796674A CN101829038B (en) | 2010-05-17 | 2010-05-17 | Winkle-removing Chinese medicament facial mask and preparation method thereof |
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| CN101829038B true CN101829038B (en) | 2012-01-25 |
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| CN103860887A (en) * | 2012-12-12 | 2014-06-18 | 王刚 | Compound Chinese angelica and Bletilla striata gum cream for treating rahagades, and its preparation method |
| CN103550511B (en) * | 2013-10-11 | 2016-03-23 | 杜江 | Vegetable composition of a kind of delay skin aging and preparation method thereof |
| CN107029113A (en) * | 2017-06-13 | 2017-08-11 | 湖南云从科技有限公司 | It is a kind of to treat pharmaceutical formulation of canthus fishtail line and preparation method thereof |
| CN115227732A (en) * | 2022-07-04 | 2022-10-25 | 山东博科医用材料有限公司 | Anti-wrinkle traditional Chinese medicine composition and preparation process thereof |
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| CN1091951A (en) * | 1993-03-13 | 1994-09-14 | 李先隆 | The complete natural skin-tendering and wrinkle-removing cosmetics |
| CN101444466B (en) * | 2007-11-28 | 2010-12-08 | 石磊 | Pure traditional Chinese medicine mask for removing blood stasis and freckles |
| CN101366690B (en) * | 2008-09-28 | 2010-11-10 | 李静 | Composition for face pack for removing speckle and wrinkle, and preparation method thereof |
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Effective date of registration: 20160119 Address after: 510660 Tianhe District, Guangzhou, Huang Village Road, No. 55, building No. 3, No. Patentee after: Gao Kang Cosmetics Manufacturing Co.,Ltd. Address before: 510665, No. two, 30, Xinzhuang Road, Yonghe street, Guangzhou, Guangdong, Luogang District Patentee before: Guangdong Yangmei Medicine Investment Co.,Ltd. |
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Address after: 510660 Tianhe District, Guangzhou, Huang Village Road, No. 55, building No. 3, No. Patentee after: GAOKANG DAILY CHEMICAL GROUP Co.,Ltd. Address before: 510660 Tianhe District, Guangzhou, Huang Village Road, No. 55, building No. 3, No. Patentee before: Gao Kang Cosmetics Manufacturing Co.,Ltd. |
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Effective date of registration: 20220624 Address after: 510000 a8016, block a, Tianrui Plaza, No. 397, Jianpeng Road, Jiahe street, Guangzhou, Guangdong Province Patentee after: Guangzhou Wanqian vermicelli Cosmetics Co.,Ltd. Address before: 510660 3rd floor, 55 Huangcun Road, Tianhe District, Guangzhou City, Guangdong Province Patentee before: GAOKANG DAILY CHEMICAL GROUP CO.,LTD. |