CN101827592A - 用可乐定治疗手术后效应诸如痉挛状态和战栗的方法 - Google Patents
用可乐定治疗手术后效应诸如痉挛状态和战栗的方法 Download PDFInfo
- Publication number
- CN101827592A CN101827592A CN200980100804A CN200980100804A CN101827592A CN 101827592 A CN101827592 A CN 101827592A CN 200980100804 A CN200980100804 A CN 200980100804A CN 200980100804 A CN200980100804 A CN 200980100804A CN 101827592 A CN101827592 A CN 101827592A
- Authority
- CN
- China
- Prior art keywords
- clonidine
- durative action
- action preparation
- spasticity
- gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4619208P | 2008-04-18 | 2008-04-18 | |
US61/046,192 | 2008-04-18 | ||
US12/408,491 US20090263443A1 (en) | 2008-04-18 | 2009-03-20 | Methods for treating post-operative effects such as spasticity and shivering with clondine |
US12/408,491 | 2009-03-20 | ||
PCT/US2009/040885 WO2009129428A2 (en) | 2008-04-18 | 2009-04-17 | Methods for treating post-operative effects such as spasticity and shivering with clonidine |
Publications (1)
Publication Number | Publication Date |
---|---|
CN101827592A true CN101827592A (zh) | 2010-09-08 |
Family
ID=41199746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN200980100804A Pending CN101827592A (zh) | 2008-04-18 | 2009-04-17 | 用可乐定治疗手术后效应诸如痉挛状态和战栗的方法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US20090263443A1 (de) |
EP (1) | EP2207545B1 (de) |
JP (1) | JP2011518787A (de) |
CN (1) | CN101827592A (de) |
WO (1) | WO2009129428A2 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE48948E1 (en) | 2008-04-18 | 2022-03-01 | Warsaw Orthopedic, Inc. | Clonidine compounds in a biodegradable polymer |
US20100239632A1 (en) | 2009-03-23 | 2010-09-23 | Warsaw Orthopedic, Inc. | Drug depots for treatment of pain and inflammation in sinus and nasal cavities or cardiac tissue |
WO2012075451A2 (en) * | 2010-12-03 | 2012-06-07 | Warsaw Orthopedic, Inc. | Clonidine and gaba compounds in a biodegradable polymer carrier |
WO2012075447A2 (en) * | 2010-12-03 | 2012-06-07 | Warsaw Orthopedic, Inc. | Compositions and methods for delivering clonidine and bupivacaine to a target tissue site |
GB201505527D0 (en) | 2015-03-31 | 2015-05-13 | Jmedtech Pte Ltd | Composition |
ES2960753T3 (es) * | 2015-09-21 | 2024-03-06 | Teva Pharmaceuticals Int Gmbh | Formulaciones de olanzapina de liberación sostenida |
JP2020511483A (ja) | 2017-03-20 | 2020-04-16 | テバ・ファーマシューティカルズ・インターナショナル・ゲーエムベーハーTeva Pharmaceuticals International GmbH | 徐放性オランザピン製剤 |
EP3691618A1 (de) | 2017-10-06 | 2020-08-12 | Foundry Therapeutics, Inc. | Implantierbare depots zur kontrollierten freisetzung therapeutischer wirkstoffe |
Family Cites Families (52)
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CA1248450A (en) * | 1984-04-05 | 1989-01-10 | Kazuo Kigasawa | Soft patch |
CA2195119C (en) * | 1995-06-09 | 2001-09-11 | Mark Chasin | Formulations and methods for providing prolonged local anesthesia |
US6113624A (en) * | 1995-10-02 | 2000-09-05 | Ethicon, Inc. | Absorbable elastomeric polymer |
EP0949905B1 (de) * | 1996-12-20 | 2001-07-18 | Alza Corporation | Injizierbare depotgelzubereitung und herstellungsverfahren |
US6294170B1 (en) * | 1997-08-08 | 2001-09-25 | Amgen Inc. | Composition and method for treating inflammatory diseases |
TW577758B (en) * | 1997-10-27 | 2004-03-01 | Ssp Co Ltd | Intra-articular preparation for the treatment of arthropathy |
CA2321004C (en) * | 1998-05-12 | 2004-05-04 | Scimed Life Systems, Inc. | Manual bone anchor placement devices |
US6632457B1 (en) * | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
US6927044B2 (en) * | 1998-09-25 | 2005-08-09 | Regeneron Pharmaceuticals, Inc. | IL-1 receptor based cytokine traps |
US6565874B1 (en) * | 1998-10-28 | 2003-05-20 | Atrix Laboratories | Polymeric delivery formulations of leuprolide with improved efficacy |
US6143314A (en) * | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
US6436099B1 (en) * | 1999-04-23 | 2002-08-20 | Sdgi Holdings, Inc. | Adjustable spinal tether |
US7220281B2 (en) * | 1999-08-18 | 2007-05-22 | Intrinsic Therapeutics, Inc. | Implant for reinforcing and annulus fibrosis |
US7329529B2 (en) * | 1999-09-03 | 2008-02-12 | Millennium Pharmaceuticals, Inc. | Ubiqutin proteases |
US7951201B2 (en) * | 1999-10-20 | 2011-05-31 | Anulex Technologies, Inc. | Method and apparatus for the treatment of the intervertebral disc annulus |
US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
WO2001045577A2 (en) * | 1999-12-06 | 2001-06-28 | Sdgi Holdings, Inc. | Intervertebral disc treatment devices and methods |
US6589549B2 (en) * | 2000-04-27 | 2003-07-08 | Macromed, Incorporated | Bioactive agent delivering system comprised of microparticles within a biodegradable to improve release profiles |
EP1347741B1 (de) * | 2001-01-03 | 2009-01-21 | Bausch & Lomb Incorporated | Wirkstoffabgabevorrichtungen mit verzögerter freisetzung mehrere stoffe enthaltend |
US7229441B2 (en) * | 2001-02-28 | 2007-06-12 | Warsaw Orthopedic, Inc. | Flexible systems for spinal stabilization and fixation |
US8617048B2 (en) * | 2001-03-09 | 2013-12-31 | Boston Scientific Scimed, Inc. | System for implanting an implant and method thereof |
MXPA01011542A (es) * | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
US6974462B2 (en) * | 2001-12-19 | 2005-12-13 | Boston Scientific Scimed, Inc. | Surgical anchor implantation device |
US8133501B2 (en) * | 2002-02-08 | 2012-03-13 | Boston Scientific Scimed, Inc. | Implantable or insertable medical devices for controlled drug delivery |
US7345065B2 (en) * | 2002-05-21 | 2008-03-18 | Allergan, Inc. | Methods and compositions for alleviating pain |
US20040109893A1 (en) * | 2002-06-25 | 2004-06-10 | Guohua Chen | Sustained release dosage forms of anesthetics for pain management |
EP1531757B1 (de) * | 2002-07-19 | 2016-09-07 | Omeros Corporation | Biologisch abbaubare triblock-copolymere, syntheseverfahren daf r und hydrogele und daraus hergestellte biologische materialien |
US20040166088A1 (en) * | 2003-01-15 | 2004-08-26 | Shalaby Shalaby W. | Polymeric precursors of non-absorbable, in situ-forming hydrogels and applications thereof |
BRPI0410953A (pt) * | 2003-05-30 | 2006-06-27 | Alza Corp | composições de depósito elastoméricas que podem ser implantadas, usos das mesmas e processo de produção |
US7144412B2 (en) * | 2003-06-25 | 2006-12-05 | Wolf Medical Enterprises, Inc. | Gold suture and method of use in wound closure |
US20050058696A1 (en) * | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
US20050059744A1 (en) * | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
EP1691852A2 (de) * | 2003-11-10 | 2006-08-23 | Angiotech International AG | Medizinsche implantate und fibroseinduzierende mittel |
US20050175709A1 (en) * | 2003-12-11 | 2005-08-11 | Baty Ace M.Iii | Therapeutic microparticles |
JP2007519756A (ja) * | 2004-01-30 | 2007-07-19 | アンジオテック インターナショナル アーゲー | 拘縮を治療するための組成物および方法 |
US7361168B2 (en) * | 2004-04-21 | 2008-04-22 | Acclarent, Inc. | Implantable device and methods for delivering drugs and other substances to treat sinusitis and other disorders |
US7410480B2 (en) * | 2004-04-21 | 2008-08-12 | Acclarent, Inc. | Devices and methods for delivering therapeutic substances for the treatment of sinusitis and other disorders |
US8741332B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for dermally treating neuropathic pain |
US8512730B2 (en) * | 2004-07-12 | 2013-08-20 | Isto Technologies, Inc. | Methods of tissue repair and compositions therefor |
US20060046961A1 (en) * | 2004-09-02 | 2006-03-02 | Mckay William F | Controlled and directed local delivery of anti-inflammatory compositions |
US20060074422A1 (en) * | 2004-09-27 | 2006-04-06 | Story Brooks J | Suture anchor and void filler combination |
US20060253100A1 (en) * | 2004-10-22 | 2006-11-09 | Medtronic, Inc. | Systems and Methods to Treat Pain Locally |
AU2005309586A1 (en) * | 2004-11-24 | 2006-06-01 | Algorx Pharmaceuticals, Inc. | Capsaicinoid gel formulation and uses thereof |
US7611494B2 (en) * | 2005-02-08 | 2009-11-03 | Confluent Surgical, Inc. | Spray for fluent materials |
US20060183786A1 (en) * | 2005-02-16 | 2006-08-17 | Chi Mei Foundation Hospital | Injectable long-acting analgesic composition comprising an ester derivative of ketorolac |
KR20120099730A (ko) * | 2005-05-20 | 2012-09-11 | 오메로스 코포레이션 | 시클로옥시게나제 저해제 및 칼슘채널 길항제 조성물 및 이의 비뇨기과 시술시의 용도를 위한 방법 |
US7610100B2 (en) * | 2005-12-30 | 2009-10-27 | Boston Scientific Neuromodulation Corporation | Methods and systems for treating osteoarthritis |
US7741273B2 (en) * | 2006-04-13 | 2010-06-22 | Warsaw Orthopedic, Inc. | Drug depot implant designs |
US20070253994A1 (en) * | 2006-04-28 | 2007-11-01 | Medtronic, Inc. | Intraspinal Drug Delivery Methods and Devices To Alleviate Chronic Pelvic Pain |
US20080021074A1 (en) * | 2006-06-29 | 2008-01-24 | Questcor Pharmaceuticals, Inc. | Pharmaceutical Compositions and Related Methods of Treatment |
US20080019970A1 (en) * | 2006-07-07 | 2008-01-24 | Gorman James R | Methods for preventing, postponing or improving the outcome of spinal device and fusion procedures |
US20080091207A1 (en) * | 2006-10-13 | 2008-04-17 | Csaba Truckai | Bone treatment systems and methods |
-
2009
- 2009-03-20 US US12/408,491 patent/US20090263443A1/en not_active Abandoned
- 2009-04-17 JP JP2011505218A patent/JP2011518787A/ja active Pending
- 2009-04-17 WO PCT/US2009/040885 patent/WO2009129428A2/en active Application Filing
- 2009-04-17 EP EP09733327.2A patent/EP2207545B1/de active Active
- 2009-04-17 CN CN200980100804A patent/CN101827592A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
US20090263443A1 (en) | 2009-10-22 |
EP2207545B1 (de) | 2016-01-06 |
WO2009129428A3 (en) | 2009-12-23 |
JP2011518787A (ja) | 2011-06-30 |
EP2207545A2 (de) | 2010-07-21 |
WO2009129428A2 (en) | 2009-10-22 |
EP2207545A4 (de) | 2012-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20100908 |