CN101826197A - Method and systems for monitoring daily activities of animal - Google Patents
Method and systems for monitoring daily activities of animal Download PDFInfo
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Abstract
The invention discloses a method and systems for monitoring daily activities of an animal, and belongs to the technical field of image data processing. The method comprises the following steps of: acquiring a background image of an animal breeding box, and putting the animal in the box; acquiring an animal image, subtracting the animal image from the background image, and marking pixel points higher than a threshold during subtracting; calculating average coordinates of the marked pixel points, and calculating movement displacement and movement distance; marking position coordinates which correspond to the movement distance and are less than or equal to a set threshold as stationary points, and marking sleeping once when the number of the continuous stationary points is more than or equal to the threshold of the number of the stationary points; and acquiring sleep rhythms, sleep time, sleep frequency and motion trail of the experimental animal according to the marked result. The invention also provides two kinds of systems for monitoring the daily activities of the animal. The method and the systems can perform non-interfering monitoring on a plurality of experimental animals for a lone time, and automatically acquire and analyze experimental data such as sleep cycle rhythms, time, frequency and motion trail of the experimental animals.
Description
Technical field
The present invention relates to image data processing technology field, particularly a kind of method and system of monitoring daily activities of animal.
Background technology
The research and development of new drug must be carried out zoopery, according to animal used as test its pharmacology and toxicity influence are assessed in the reaction of medicine.Generally, because medicine might cause the change in animal physiological and the behavior, therefore monitoring physiological parameter and the behavioral activity of animal, obtain relevant data, is very important for estimating a kind of medicine.Except drug study, the research of gene and animal physiological, behavior and disease aspects such as relation each other is also extremely important, and the researchist need know that the sudden change of some specific gene can cause the variation of which physiology and behavior, perhaps pathology.Physiology and behavior parameters such as heartbeat, blood pressure, blood oxygen concentration, body temperature, food-intake, amount of drinking water, oxygen utilization, autokinetic movement, non-autokinetic movement, event trace, the rhythm and pace of moving things and sleep that present animal pharmaceuticals experiment and gene studies generally need be monitored animal.Aspect the monitoring animal behavior, mainly concentrate at present aspects such as amount of drinking water, food-intake, body temperature, blood pressure and movement locus tracking to animal used as test, wherein have and adopt the video monitoring to add the supplementary instrument method, also have and utilize led array to survey.
In actual applications, sleep of animal and rhythm and pace of moving things situation are very important indexs, for the drug research particular importance relevant with the sleep and the rhythm and pace of moving things, for example hypnotic etc. some improve the medicine of sleep; Simultaneously also very important for zoologizeing in the body materials such as gene relevant with the sleep and the rhythm and pace of moving things, serotonin for example.Aspect parameter acquiring such as the sleep cycle rhythm and pace of moving things, time and the number of times of animal used as test and analysis, similar method that prior art adopts mostly and monitoring human is slept, promptly on health, implant or additional electrodes is surveyed brain wave or flesh streaming current, come monitoring sleep status according to the variation of brain wave or flesh streaming current.But for animal used as test, this method for supervising complicated operation, the experimenter is had relatively high expectations, and once experiment can only be write down the sleep quality of single animal, and the experimental data of a large amount of animals of pathology requirement of experiment of pharmacology, toxicological experiment and gene-correlation, therefore this method is not suitable for extensive use.In addition, the method for implant electrode can damage the animal health, can produce bad influence to experimental result; Some simple experiment can be by the method for Direct observation, judges whether daily routines situation such as animal sleep changes, but this method science not is subjected to man's activity bigger, and its experimental result is easy to generate bigger error.
Summary of the invention
For science obtains the experimental datas such as the sleep cycle rhythm and pace of moving things, the length of one's sleep, sleep number of times and movement locus of animal used as test exactly, improve experimental work efficient, the invention provides a kind of method of monitoring daily activities of animal, described method comprises:
Steps A: gather the background image of closed animal feeding case, and many animals used as test are put into described closed animal feeding case;
Step B: the sampling instant that is setting in advance, gather the image of animal used as test in the described closed animal feeding case, the image that collects and described background image are carried out absolute difference subtract, and be higher than the pixel that preestablishes display threshold in the image that obtains after difference subtracted and carry out mark;
Step C: the average coordinates that calculates the pixel that has mark, described average coordinates is set at the position coordinates of animal used as test in current sampling instant, and calculates moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to described position coordinates;
Step D: moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant compared, and will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of described threshold value; When the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep;
Step e: in the position coordinates of each sampling instant, the length of one's sleep of mark and the number of sleep number of times and rest point, draw sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to animal used as test.
Described steps A specifically comprises:
Steps A 1: closed animal feeding case is divided into the separate space of a plurality of identical sizes, and passes through the background image of the described closed animal feeding case of camera collection;
Steps A 2: the separate space of many animals used as test being put into each identical size respectively.
Described step e specifically comprises:
Step e 1: animal used as test is stored in the computer data file in the position coordinates of each sampling instant, the length of one's sleep of mark and the number of sleep number of times and rest point;
Step e 2: read the data in the described data file, and described data are divided into a plurality of sections, calculate the arithmetic mean and the standard deviation of data in each section according to predefined step value;
Step e 3:, analyze and draw out sleep rhythm, the length of one's sleep, sleep number of times and the path curves figure of animal used as test according to described arithmetic mean and standard deviation.
There is a camera mounting hole center, top of described closed animal feeding case, and there is quiet fan mounting hole a side, and there is a plurality of drinking-water hole both sides.
The invention provides a kind of system of monitoring daily activities of animal, described system comprises:
First acquisition module is used to gather and send the background image of closed animal feeding case;
Second acquisition module is used in the sampling instant that sets in advance, and gathers and send the image of animal used as test in the described closed animal feeding case;
Difference subtracts module, is used to receive the image that described first acquisition module and second acquisition module send, and the image that receives is carried out absolute difference subtracts, and sends difference and subtracts the result;
Mark module is used to receive described difference and subtracts the difference that module sends and subtract the result, and difference subtracted is higher than the pixel that preestablishes display threshold among the result and carries out mark, sends the mark result;
Calculate setting module, be used to receive the mark result that described mark module sends, calculate the average coordinates of the pixel that has mark according to described mark result, described average coordinates is set at the position coordinates of animal used as test in current sampling instant, and calculate moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to described position coordinates, send result of calculation;
Compare mark module, be used to receive the result of calculation that described calculating setting module sends, and moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant compared, will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of described threshold value; When the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, sends relatively mark result;
Output module is used for according to described calculating setting module and the relatively result of calculation that sends of mark module and relatively mark result, sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of output animal used as test.
Described calculating setting module comprises:
First computing unit is used to receive the mark result that described mark module sends, and according to the average coordinates that described mark result calculates the pixel that has mark, sends described average coordinates;
Setup unit is used to receive the average coordinates that described first computing unit sends, and described average coordinates is set at the position coordinates of animal used as test in current sampling instant, sends described position coordinates;
Second computing unit is used to receive the position coordinates that described setup unit sends, and calculates moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to described position coordinates, sends described moving displacement and move distance.
Described relatively mark module comprises:
Comparing unit is used to receive the moving displacement that described second computing unit sends, and moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant is compared, and sends comparative result;
Indexing unit, be used to receive the comparative result that described comparing unit sends, and will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of described threshold value, and when the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, sends the mark result.
Described output module comprises:
Storage unit is used to receive position coordinates and mark result that described setup unit and indexing unit send, and described position coordinates and mark result are stored in the computer data file;
Read synchronous unit, be used for reading the data of described data file, and described data are synchronized on axle unified time according to its acquisition time;
The segmental averaging unit is used for according to predefined step value described data being divided into a plurality of sections, and calculates the arithmetic mean and the standard deviation of data in each section, sends described arithmetic mean and standard deviation;
The sleep analysis unit is used to receive described arithmetic mean and standard deviation, and analyzes sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to described arithmetic mean and standard deviation, sends analysis result;
Drawing unit is used to receive the analysis result that described sleep analysis unit sends, and draws out sleep rhythm, the length of one's sleep, sleep number of times and the path curves figure of animal used as test according to described analysis result.
The present invention also provides the system of another kind of monitoring daily activities of animal, and described system comprises closed animal feeding case, illuminating lamp, video acquisition module and computing machine;
Described illuminating lamp is installed in the top of described closed animal feeding case, and the circadian rhythm that is used to set in the described closed animal feeding case changes;
Described video acquisition module is used to gather the video image in the described closed animal feeding case, and gives described computing machine with described transmission of video images;
Described computing machine is used for receiving and storing described video image, and goes out sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to described video image analysis;
Described video acquisition module links to each other with described computing machine by data line.
Described video acquisition module comprises video acquiring unit and A/D converting unit;
Described video acquiring unit is used for obtaining in real time the video image in the described closed animal feeding case, and the video image that gets access to is sent to described A/D converting unit;
Described A/D converting unit is used to receive the video image that described video acquiring unit sends, and described video image is carried out the Digital Discrete processing, sends to described computing machine.
Beneficial effect: the method and system of monitoring daily activities of animal provided by the invention; can carry out noiseless monitoring to many animals used as test for a long time; and obtain and analyze the experimental datas such as the sleep cycle rhythm and pace of moving things, the length of one's sleep, sleep number of times and movement locus of animal used as test automatically; so that carry out the experimental study of the aspects such as pharmacology, genetics and Neurobiology relevant, particularly relevant research with sleep with the animal daily behavior.
Description of drawings
Fig. 1 is the schematic appearance of the closed animal feeding case of the embodiment of the invention;
Fig. 2 is the method flow diagram of embodiment of the invention monitoring daily activities of animal;
Fig. 3 is the software interface synoptic diagram that the embodiment of the invention is obtained animal feeding case reference picture;
Fig. 4 is the software interface synoptic diagram of the real-time monitoring experiment mouse of embodiment of the invention activity;
Fig. 5 is the software interface synoptic diagram of the real-time monitoring experiment mouse of embodiment of the invention position;
Fig. 6 is the software function synoptic diagram that the embodiment of the invention realizes monitoring experiment animal activity method;
Fig. 7 is the software interface synoptic diagram of the data that monitor of embodiment of the invention Computer Analysis;
Fig. 8 is the software interface synoptic diagram of embodiment of the invention computing machine loading data file;
Fig. 9 is one day movable situation synoptic diagram of experiment mice of embodiment of the invention record;
Figure 10 is four days movable situation synoptic diagram of experiment mice of embodiment of the invention record;
Figure 11 be embodiment of the invention record experiment mice amount of exercise curve map and the length of one's sleep curve map;
Figure 12 is the circadian rhythm change curve of four experiment mices of embodiment of the invention record;
Figure 13 is the movement locus figure of an experiment mice of embodiment of the invention record;
Figure 14 is the experimental data and the experimental data comparison diagram of surveying EEG of embodiment of the invention record;
Figure 15 is the system architecture synoptic diagram of first kind of monitoring daily activities of animal providing of the embodiment of the invention;
Figure 16 is the system architecture synoptic diagram of second kind of monitoring daily activities of animal providing of the embodiment of the invention.
Embodiment
For making the purpose, technical solutions and advantages of the present invention clearer, embodiment of the present invention is described further in detail below in conjunction with accompanying drawing.
The embodiment of the invention provides a kind of method of monitoring daily activities of animal; this method can be carried out glitch-free monitoring to many animals used as test simultaneously; and based on the monitor data of daily activities of animal; analysis obtains the length of one's sleep, the experimental datas such as sleep number of times and the sleep cycle rhythm and pace of moving things of animal used as test, and behaviouristics data such as the movement locus of animal used as test and autokinetic movement amount can also be provided simultaneously.Present embodiment is an example to monitor four mouse, sets forth the technical scheme that the embodiment of the invention provides.In order to monitor the daily routines of four mouse more easily, present embodiment is placed on four mouse respectively in the closed opaque rectangular parallelepiped animal feeding case (as shown in Figure 1), this closed animal feeding case is of a size of 50 * 50 * 80cm (length * wide * height), one side of animal feeding case is opened the door, animal feeding case inside is divided into four independently boothes of 20 * 20cm, each booth is raised a mouse respectively, is independent of each other between the mouse; Center, animal feeding box top has the camera mounting hole 1 of a 10cm, is used to install infrared camera, so that gather the daily routines data of mouse; Four independently all have bedding and padding, food and water in the booth; The opposite side of animal feeding case has the circular hole 2 that diameter is 12cm, is used to install the quiet fan of 12cm, to guarantee the circulation of air in the animal feeding case; Animal feeding case both sides have four drinking-water holes, water bottle can be inserted wherein the drinking-water for mouse; LED controllable light illuminating lamp is installed in the top of animal feeding case, and this illuminating lamp is controlled by a programmable clock switch, can set up the variation round the clock of animal feeding case inside according to requirement of experiment on their own.Before mouse is monitored, evenly spread bedding and padding in four independent boothes in the animal feeding case, put into an amount of food, water bottle is full of cleandrinking water, the drinking-water hole of packing into.
Referring to Fig. 2, the method for the monitoring daily activities of animal that the embodiment of the invention provides specifically may further comprise the steps:
Step 201: gather the background image of closed animal feeding case, and four mouse are put into four independent boothes of closed animal feeding case inside respectively;
Before four mouse are put into closed animal feeding case, gather the background image of closed animal feeding case by the infrared camera that is installed in closed animal feeding box top center, and with this background image as the reference image, as shown in Figure 3; Four mouse are placed into after four independent boothes of closed animal feeding case, can realize monitoring in real time by infrared camera, as shown in Figure 4;
Step 202: in the sampling instant that sets in advance, infrared camera is with the image of the closed animal feeding case of the speed acquisition of 5 frame/seconds, and the background image of the image that collects and closed animal feeding case is carried out absolute difference subtracts;
Step 203: be higher than the pixel that preestablishes display threshold in the image after absolute difference subtracted and be set at 255, be lower than the pixel that preestablishes display threshold and be set at 0, obtain new binary map;
Display threshold can be set according to the color of animal used as test fur and the difference of background color;
Step 204: utilize Fourier transform to carry out image and remove and to make an uproar, and will be divided into four independent boothes respectively except that the image after making an uproar;
To be specially except that the image after making an uproar is divided into four independent boothes respectively: will arrive in the booth corresponding to this mouse place except that the image division that belongs to same mouse after making an uproar;
Step 205: calculate value in each booth respectively and be the average coordinates of 255 pixel, and this average coordinates is set at the position coordinates of the mouse corresponding with this booth;
As shown in Figure 5, bright position coordinates of representing a mouse of each white of upper right side among the figure;
Step 206:, calculate and store moving displacement and the move distance of current sampling instant mouse with respect to previous frame image acquisition position coordinates constantly according to the position coordinates of mouse;
In actual applications, can set the activity time of monitoring mouse according to actual conditions, i.e. the activity by infrared camera monitoring mouse in the time of setting, and with the data storage that monitors in calculate in the preassigned data file clip directory; According to moving displacement and the move distance of the mouse that calculates, can obtain the movement locus of mouse; By the moving displacement of the mouse in statistics a period of time, can react the motion state of interior mouse during this period of time;
Step 207: moving displacement and the predefined moving displacement threshold value of mouse in each sampling instant compared, and will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of this threshold value, and when the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, stores the length of one's sleep, sleep number of times and rest point number;
In actual applications, can experimental concrete condition set the time interval of judging whether mouse sleeps, the mouse sleep time that present embodiment is set is spaced apart 35 seconds, promptly in 35 second sampling time, if mouse keeps the health transfixion, think that then mouse is in sleep state; By the length of one's sleep of the mouse in statistics a period of time, can react the sleep state of interior mouse during this period of time;
In addition, can also use rat to realize present embodiment, can set rat and be spaced apart 40 seconds the length of one's sleep, promptly in 40 second sampling time,, think that then rat is in sleep state if rat keeps the health transfixion;
In actual applications, the length of one's sleep, sleep number of times and rest point number can store in the calculating in the preassigned data file clip directory;
Step 208: read the data in the computer data file, and data are divided into a plurality of sections, calculate the arithmetic mean and the standard deviation of data in each section according to predefined step value;
Step 209:, analyze and draw out sleep rhythm, the length of one's sleep, sleep number of times and the path curves figure of mouse according to arithmetic mean that calculates and standard deviation.
Present embodiment has been realized the monitoring to four mouse daily routines, and these four mouse are respectively independently movable in the space separately; Closed animal feeding case provides totally-enclosed and glitch-free living space for four mouse, has also guaranteed drinking-water and the food of mouse simultaneously; By the brightness of illumination of control LED controllable light illuminating lamp, realized that the circadian rhythm in the closed animal feeding case enclosure space changes.
In actual applications, can closed animal feeding case be divided into a plurality of independently boothes, and then realize monitoring many animal used as test daily routines according to the animal used as test physical size; The view data of infrared camera collection can be transferred to computing machine by data line and video frequency collection card, and computing machine is finished the processing to video data.Video frequency collection card can be installed in the PCI expansion slot of computing machine, perhaps is connected with computing machine by other interface modes, for example usb mode.
In concrete production practices; the technical scheme that present embodiment provides can realize by computer software; computer software is used to realize the functions such as record, storage and analysis of animal used as test daily routines; this software interface partly is made of reference picture window, realtime graphic window, the adjusting of image display threshold, programmed control button, animal used as test position coordinates and move distance display field and data storage hurdle etc. specifically, as shown in Figure 6.After obtaining animal used as test daily routines data, computer software is analyzed data, obtains the experimental results such as sleep rhythm, the length of one's sleep, sleep number of times and movement locus of animal used as test.Computer software judges whether animal used as test enters dormant foundation and be: (mouse is 35 seconds to the position coordinates of animal used as test in the predefined time continuously, rat is 40 seconds) in remain unchanged, think that then animal used as test is in sleep state, otherwise think that letting animals feed is kept in motion.The main interface of data analysis as shown in Figure 7, point " load " button can be set the path (as shown in Figure 8) of the file that needs loading, just can this document be joined in the listed files that to analyze after configuring the path by " Add " button, just can simply map to the file that adds this moment, clicks " plot " button.Fig. 9 shows the active situation of animal used as test in the time.In addition, can also utilize asterisk wildcard once to add a plurality of files, and a plurality of files that add are simply mapped, obtain the active situation (as shown in figure 10) of animal used as test in continuous four days.Clicking " Even plot " button on average maps (as shown in figure 11) to reading in data at times with selected time segment length, present embodiment was a time period length with 12 hours, the average piecewise analysis result who obtains, wherein two curves are respectively animal movement discharge curve and animal sleep time curve, article two, curve is a complementary relationship, be amount of exercise at least the length of one's sleep many, otherwise in like manner.Just can click " phase display " button in segmentation statistics back, the rhythm and pace of moving things variation diagram (as shown in figure 12) of four mouse draws respectively, wherein Figure 12 one has four hurdles, an experiment mice sleep rhythm situation of change is represented on each hurdle respectively, write down continuous three days data altogether, three curves in each hurdle are represented mice sleep rhythm and pace of moving things situation of change every day respectively; Click the movement locus figure that " histom " obtains animal, as shown in figure 13.
Experimental data shows, and determines that by surveying brain wave the method for animal sleep state compares, experimental results such as the animal sleep rhythm and pace of moving things that the method that the embodiment of the invention provides obtains, the length of one's sleep, sleep number of times and movement locus accurately and reliably, as shown in figure 14.The method that the embodiment of the invention provides is simple to operate, and science is accurate, operating personnel is required low, animal used as test is not had any interference, and once can write down and analyze the daily routines state of many animals used as test simultaneously, is fit to extensive the use.
Referring to Figure 15, the embodiment of the invention provides a kind of system of monitoring daily activities of animal, and this system comprises:
First acquisition module is used to gather and send the background image of closed animal feeding case;
Second acquisition module is used in the sampling instant that sets in advance, and gathers and send the image of animal used as test in the closed animal feeding case;
Difference subtracts module, is used to receive the image that first acquisition module and second acquisition module send, and the image that receives is carried out absolute difference subtracts, and sends difference and subtracts the result;
Mark module is used to receive difference and subtracts the difference that module sends and subtract the result, and difference subtracted is higher than the pixel that preestablishes display threshold among the result and carries out mark, sends the mark result;
Calculate setting module, be used to receive the mark result that mark module sends, calculate the average coordinates of the pixel that has mark according to the mark result, average coordinates is set at the position coordinates of animal used as test in current sampling instant, and calculate moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to position coordinates, send result of calculation;
Compare mark module, be used to receive the result of calculation of calculating the setting module transmission, and moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant compared, will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of threshold value; When the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, sends relatively mark result;
Output module is used for according to calculating setting module and the relatively result of calculation that sends of mark module and relatively mark result, sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of output animal used as test.
Wherein, calculating setting module comprises:
First computing unit is used to receive the mark result that mark module sends, and according to the average coordinates that the mark result calculates the pixel that has mark, sends average coordinates;
Setup unit is used to receive the average coordinates that first computing unit sends, and average coordinates is set at the position coordinates of animal used as test in current sampling instant, sends position coordinates;
Second computing unit is used to receive the position coordinates that setup unit sends, and calculates moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to position coordinates, sends moving displacement and move distance.
Wherein, relatively mark module comprises:
Comparing unit is used to receive the moving displacement that second computing unit sends, and moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant is compared, and sends comparative result;
Indexing unit, be used to receive the comparative result that comparing unit sends, and will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of threshold value, and when the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, sends the mark result.
Wherein, output module comprises:
Storage unit is used to receive position coordinates and mark result that setup unit and indexing unit send, and position coordinates and mark result are stored in the computer data file;
Read synchronous unit, be used for the data of read data files, and data are synchronized on axle unified time according to its acquisition time;
The segmental averaging unit is used for according to predefined step value data being divided into a plurality of sections, and calculates the arithmetic mean and the standard deviation of data in each section, sends arithmetic mean and standard deviation;
The sleep analysis unit is used to receive arithmetic mean and standard deviation, and analyzes sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to arithmetic mean and standard deviation, sends analysis result;
Drawing unit is used to receive the analysis result that the sleep analysis unit sends, and draws out sleep rhythm, the length of one's sleep, sleep number of times and the path curves figure of animal used as test according to analysis result.
Referring to Figure 16, the embodiment of the invention also provides the system of another kind of monitoring daily activities of animal, and this system comprises closed animal feeding case, illuminating lamp, video acquisition module and computing machine.Wherein, illuminating lamp is installed in the top of closed animal feeding case, and the circadian rhythm that is used to set in the animal feeding case changes; Video acquisition module is used to gather the video image in the closed animal feeding case, and gives computing machine with transmission of video images; Computing machine is used for receiving and store video images, and goes out animal sleep rhythm, the length of one's sleep, sleep number of times and movement locus according to video image analysis.Video acquisition module links to each other with computing machine by data line.
Video acquisition module comprises video acquiring unit and A/D converting unit; The video acquiring unit is used for obtaining in real time the video image in the closed animal feeding case, and the video image that gets access to is sent to the A/D converting unit; The A/D converting unit is used for the video image that the receiver, video acquiring unit sends, and video image is carried out the Digital Discrete processing, sends to computing machine.In actual applications, the video acquiring unit can but be not limited to infrared camera; The A/D converting unit can but be not limited to video frequency collection card; Illuminating lamp can but be not limited to program controlled LED lamp; Computer Storage is useful on the software of analyzing animal daily routines data.
Present embodiment adopts the daily exercise of infrared camera recording laboratory animal, behind the move distance record and analysis software processing stored in the computing machine, obtain the human behavior science data such as the variation of the sleep cycle rhythm and pace of moving things, the length of one's sleep, sleep number of times and movement locus of observed animal used as test.
The method and system of monitoring daily activities of animal provided by the invention; can carry out noiseless monitoring to many animals used as test for a long time; and obtain and analyze the experimental datas such as the sleep cycle rhythm and pace of moving things, the length of one's sleep, sleep number of times and movement locus of animal used as test automatically; so that carry out the experimental study of the aspects such as pharmacology, genetics and Neurobiology relevant, particularly relevant research with sleep with the animal daily behavior.
The above only is preferred embodiment of the present invention, and is in order to restriction the present invention, within the spirit and principles in the present invention not all, any modification of being done, is equal to replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. the method for a monitoring daily activities of animal is characterized in that, described method comprises:
Steps A: gather the background image of closed animal feeding case, and many animals used as test are put into described closed animal feeding case;
Step B: the sampling instant that is setting in advance, gather the image of animal used as test in the described closed animal feeding case, the image that collects and described background image are carried out absolute difference subtract, and be higher than the pixel that preestablishes display threshold in the image that obtains after difference subtracted and carry out mark;
Step C: the average coordinates that calculates the pixel that has mark, described average coordinates is set at the position coordinates of animal used as test in current sampling instant, and calculates moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to described position coordinates;
Step D: moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant compared, and will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of described threshold value; When the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep;
Step e: in the position coordinates of each sampling instant, the length of one's sleep of mark and the number of sleep number of times and rest point, draw sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to animal used as test.
2. the method for monitoring daily activities of animal as claimed in claim 1 is characterized in that, described steps A specifically comprises:
Steps A 1: closed animal feeding case is divided into the separate space of a plurality of identical sizes, and passes through the background image of the described closed animal feeding case of camera collection;
Steps A 2: the separate space of many animals used as test being put into each identical size respectively.
3. the method for monitoring daily activities of animal as claimed in claim 1 is characterized in that, described step e specifically comprises:
Step e 1: animal used as test is stored in the computer data file in the position coordinates of each sampling instant, the length of one's sleep of mark and the number of sleep number of times and rest point;
Step e 2: read the data in the described data file, and described data are divided into a plurality of sections, calculate the arithmetic mean and the standard deviation of data in each section according to predefined step value;
Step e 3:, analyze and draw out sleep rhythm, the length of one's sleep, sleep number of times and the path curves figure of animal used as test according to described arithmetic mean and standard deviation.
4. as the method for the described monitoring daily activities of animal of arbitrary claim among the claim 1-3; it is characterized in that; there is a camera mounting hole center, top of described closed animal feeding case, and there is quiet fan mounting hole a side, and there is a plurality of drinking-water hole both sides.
5. the system of a monitoring daily activities of animal is characterized in that, described system comprises:
First acquisition module is used to gather and send the background image of closed animal feeding case;
Second acquisition module is used in the sampling instant that sets in advance, and gathers and send the image of animal used as test in the described closed animal feeding case;
Difference subtracts module, is used to receive the image that described first acquisition module and second acquisition module send, and the image that receives is carried out absolute difference subtracts, and sends difference and subtracts the result;
Mark module is used to receive described difference and subtracts the difference that module sends and subtract the result, and difference subtracted is higher than the pixel that preestablishes display threshold among the result and carries out mark, sends the mark result;
Calculate setting module, be used to receive the mark result that described mark module sends, calculate the average coordinates of the pixel that has mark according to described mark result, described average coordinates is set at the position coordinates of animal used as test in current sampling instant, and calculate moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to described position coordinates, send result of calculation;
Compare mark module, be used to receive the result of calculation that described calculating setting module sends, and moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant compared, will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of described threshold value; When the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, sends relatively mark result;
Output module is used for according to described calculating setting module and the relatively result of calculation that sends of mark module and relatively mark result, sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of output animal used as test.
6. the system of monitoring daily activities of animal as claimed in claim 5 is characterized in that, described calculating setting module comprises:
First computing unit is used to receive the mark result that described mark module sends, and according to the average coordinates that described mark result calculates the pixel that has mark, sends described average coordinates;
Setup unit is used to receive the average coordinates that described first computing unit sends, and described average coordinates is set at the position coordinates of animal used as test in current sampling instant, sends described position coordinates;
Second computing unit is used to receive the position coordinates that described setup unit sends, and calculates moving displacement and the move distance of animal used as test with respect to the position coordinates of last sampling instant according to described position coordinates, sends described moving displacement and move distance.
7. the system of monitoring daily activities of animal as claimed in claim 6 is characterized in that, described relatively mark module comprises:
Comparing unit is used to receive the moving displacement that described second computing unit sends, and moving displacement and the predefined moving displacement threshold value of animal used as test in each sampling instant is compared, and sends comparative result;
Indexing unit, be used to receive the comparative result that described comparing unit sends, and will be labeled as a rest point smaller or equal to the pairing position coordinates of the moving displacement of described threshold value, and when the number of continuous rest point during more than or equal to predefined rest point number threshold value, the sampling time of the continuous rest point correspondence of mark is a length of one's sleep, sends the mark result.
8. the system of monitoring daily activities of animal as claimed in claim 7 is characterized in that, described output module comprises:
Storage unit is used to receive position coordinates and mark result that described setup unit and indexing unit send, and described position coordinates and mark result are stored in the computer data file;
Read synchronous unit, be used for reading the data of described data file, and described data are synchronized on axle unified time according to its acquisition time;
The segmental averaging unit is used for according to predefined step value described data being divided into a plurality of sections, and calculates the arithmetic mean and the standard deviation of data in each section, sends described arithmetic mean and standard deviation;
The sleep analysis unit is used to receive described arithmetic mean and standard deviation, and analyzes sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to described arithmetic mean and standard deviation, sends analysis result;
Drawing unit is used to receive the analysis result that described sleep analysis unit sends, and draws out sleep rhythm, the length of one's sleep, sleep number of times and the path curves figure of animal used as test according to described analysis result.
9. the system of a monitoring daily activities of animal is characterized in that, described system comprises closed animal feeding case, illuminating lamp, video acquisition module and computing machine;
Described illuminating lamp is installed in the top of described closed animal feeding case, and the circadian rhythm that is used to set in the described closed animal feeding case changes;
Described video acquisition module is used to gather the video image in the described closed animal feeding case, and gives described computing machine with described transmission of video images;
Described computing machine is used for receiving and storing described video image, and goes out sleep rhythm, the length of one's sleep, sleep number of times and the movement locus of animal used as test according to described video image analysis;
Described video acquisition module links to each other with described computing machine by data line.
10. the system of monitoring daily activities of animal as claimed in claim 9 is characterized in that, described video acquisition module comprises video acquiring unit and A/D converting unit;
Described video acquiring unit is used for obtaining in real time the video image in the described closed animal feeding case, and the video image that gets access to is sent to described A/D converting unit;
Described A/D converting unit is used to receive the video image that described video acquiring unit sends, and described video image is carried out the Digital Discrete processing, sends to described computing machine.
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