CN101817798B - 制备来氟米特的绿色工艺 - Google Patents
制备来氟米特的绿色工艺 Download PDFInfo
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- CN101817798B CN101817798B CN200910025144.1A CN200910025144A CN101817798B CN 101817798 B CN101817798 B CN 101817798B CN 200910025144 A CN200910025144 A CN 200910025144A CN 101817798 B CN101817798 B CN 101817798B
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- leflunomide
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- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
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CN200910025144.1A CN101817798B (zh) | 2009-02-26 | 2009-02-26 | 制备来氟米特的绿色工艺 |
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CN200910025144.1A CN101817798B (zh) | 2009-02-26 | 2009-02-26 | 制备来氟米特的绿色工艺 |
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CN101817798A CN101817798A (zh) | 2010-09-01 |
CN101817798B true CN101817798B (zh) | 2014-04-16 |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3310755A4 (en) * | 2015-06-17 | 2019-02-27 | Biocon Limited | NEW PROCESS FOR THE PREPARATION OF TÉRIFLUNOMIDE |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102786489A (zh) * | 2012-07-09 | 2012-11-21 | 大连理工大学 | 一种5-甲基异噁唑-4-甲酸乙酯的制备方法 |
CN107311954B (zh) * | 2017-05-17 | 2020-04-07 | 力赛生物医药科技(厦门)有限公司 | 来氟米特晶型化合物、制备方法及其应用 |
CN109180599A (zh) * | 2018-09-03 | 2019-01-11 | 深圳市新阳唯康科技有限公司 | 一种来氟米特新晶型化合物及其制备方法 |
CN110669022B (zh) * | 2019-10-31 | 2022-03-11 | 常州沃腾化工科技有限公司 | 一种5-甲基异噁唑-4-甲酸的微通道连续化制备方法 |
CN111233779B (zh) * | 2020-04-02 | 2021-08-20 | 廖文英 | 一种来氟米特的制备方法 |
CN113024437B (zh) * | 2021-03-19 | 2022-05-06 | 苏州百灵威超精细材料有限公司 | 4’,6-二脒基-2-苯基吲哚二盐酸盐的制备方法 |
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WO2007086076A2 (en) * | 2006-01-24 | 2007-08-02 | Unichem Laboratories Limited | An improved process for preparation of leflunomide |
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Non-Patent Citations (2)
Title |
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5-甲基-4-异噁唑甲酸的合成;于锋臣等;《齐鲁药事》;20041231;第23卷(第6期);40-41 * |
于锋臣等.5-甲基-4-异噁唑甲酸的合成.《齐鲁药事》.2004,第23卷(第6期),40-41. |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3310755A4 (en) * | 2015-06-17 | 2019-02-27 | Biocon Limited | NEW PROCESS FOR THE PREPARATION OF TÉRIFLUNOMIDE |
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Free format text: FORMER OWNER: CHANGZHOU YABANG PHARMACEUTICAL CO., LTD. CHANGZHOU YABANG PHARMACEUTICAL + CHEMICAL CO., LTD. Effective date: 20150430 Owner name: CHANGZHOU YABANG PHARMACEUTICAL CO., LTD. Free format text: FORMER OWNER: JIANGSU YABANG AIPUSEN PHARMACEUTICAL CO., LTD. Effective date: 20150430 |
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Effective date of registration: 20150430 Address after: 213200 No. 6 Chang Dong Road, Jiangsu, Jintan Patentee after: Changzhou Yabang Pharmaceutical Co., Ltd. Address before: 224600 Jiangsu province Xiangshui County Economic Development Zone Patentee before: Jiangsu Yabang Aipusen Pharmaceutical Co., Ltd. Patentee before: Changzhou Yabang Pharmaceutical Co., Ltd. Patentee before: Changzhou Yabang Pharmaceutical & Chemical Co., Ltd. |