CN101810671B - Chinese medicinal preparation for treating AIDS and preparation method thereof - Google Patents
Chinese medicinal preparation for treating AIDS and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a Chinese medicinal preparation for treating AIDS and a preparation method thereof. The Chinese medicinal preparation is prepared from the following raw materials: astragalus, pilose asiabell root, black ant, lucid ganoderma, Indian buead, fiveleaf gynostemma herb and liquoric root. The Chinese medicinal preparation can be prepared into any Chinese medicinal preparation which is easy to administrate and carry and is used for preparing a medicament for treating the AIDS. 120 cases of clinical results of five medical institutions show that the Chinese medicinal preparation can obviously improve symptoms of patients with AIDS and improve quality of life of the patients with AIDS. The Chinese medicinal preparation has no adverse reaction in clinical application.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine preparation and preparation method thereof, particularly a kind of Chinese medicine preparation of treating AIDS and preparation method thereof.
Background technology:
(Acquirid Immune Deficiency Syndrome is to threaten one of the most serious disease of human life's health AIDS) to AIDS.Since the U.S. found AIDS in 1981, AIDS was just as " incurable disease ", in case catch just can by the people repel away from and can only wait for dead coming, suffer all kinds of discriminating against and misery.Show that according to latest data AIDS is so far popular, approximately existing 6,000 ten thousand people in the whole world have infected HIV, and 2,500 ten thousand people die from AIDS-related diseases." AIDS epidemiological report in 2009 " that UNAIDS announces pointed out; The whole world nearly 3,340 ten thousand (3110-3580 ten thousand) patients infected hiv in 2008; 2,700,000 (240-300 ten thousand) New Development the infecteds, 2,000,000 people (170-240 ten thousand) die from AIDS.According to statistics, at the bottom of in October, 2009, the inland of China totally reports AIDSinfected patient's hentriaconta-19,877 examples, AIDS patient 102,323 examples wherein, dead 49,845 examples.
Medical circle thinks that all AIDS still can not be referred to as the disease that can cure.So far, also do not have a kind of efficacious therapy method treatment of AIDS fully, still have every year a large amount of sufferers to die from AIDS.Do not come out owing to still there is effective vaccine so far, efficient ART (HAART) is still the main means of resisting the HIV aids infection in the present world wide.Yet the HAART compliance is poor, and its toxic and side effects makes the patient not tolerate, and costs an arm and a leg, and many patients are unable to be born.And result of study shows: the symptom and sign determined curative effect (like weak, diarrhoea, heating, erythra etc.) of Chinese medicine to improving AIDS; Can obviously improve patient's life quality; The part untoward reaction that HAART (HAART) is caused has therapeutical effect (like digestive tract) preferably; Immunologic function to raising and stable patient has certain function.Therefore, from little, cheap other natural drugs of Chinese medicine of wide material sources, toxic and side effects, seeking efficiently, inverase has become one of important subject of relevant AIDS research.
Summary of the invention
The inventor sums up from clinical practice; In conjunction with the modern pharmacological research achievement; From clinical proved recipe, filter out the prescription that meets the Chinese traditional treatment AIDS rule of treatment, and, finally confirmed by the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae through the clinical trial checking; Through suitable processing, the process of preparing Chinese medicine, extraction, processed the Chinese medicine preparation that is used to treat AIDS.The therapeutic effect of this Chinese medicine preparation is good, safe and reliable, low price.The present invention simultaneously also provides the method for preparing of clinical suitable dosage form.
Technical scheme of the present invention is based on tcm theory, formulates to the pathogeny of AIDS.Formulated with replenishing QI to invigorate the spleen the present invention is directed to the sings and symptoms that aids patient shows clinically, strengthening vital QI to eliminate pathogenic factors, diuretic are by the bonded Therapeutic Principle of wetting phase, with the aids patient of this rule of treatment treatment aids infection virus.Simultaneously according to inventor's clinical experience and with reference to the modern pharmacology achievement in research for many years, filter out and have with replenishing QI to invigorate the spleen, by the natural Chinese medicine of wet function such as eliminating evil, by the traditional Chinese medical science rule of treatment prescription of drafting, and this prescription is developed to new Chinese medicine preparation.This Chinese medicine preparation therapeutic effect in clinical research is obvious.
The present invention realizes with following way:
The present invention treats the Chinese medicine preparation of AIDS and is processed by following parts by weight of traditional Chinese medicines raw material:
Radix Astragali 5-20g Radix Codonopsis 5-20g Formica fusca 10-15g Ganoderma 10-20g Poria 5-15g Herb Gynostemmae Pentaphylli 10-20g Radix Glycyrrhizae 3-8g.
The present invention supplies the method for preparing of the Chinese medicine preparation of clinical use:
(1) method for preparing one: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot decocte with water; Extract 1-3 time, filter, remove slag the water extract; Merge the water extract, filtrating concentrates, by the conventional formulation technology of relevant dosage form; Add appropriate amount of auxiliary materials and process corresponding dosage forms, promptly get.
(2) method for preparing two: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot, decocte with water is extracted 1-3 time; Filter, remove slag the water extract, merge the water extract, filtrating is concentrated into the clear paste that relative density is 1.03-1.15; Put coldly, add ethanol and be 50%-75%, stir, leave standstill to containing the alcohol amount; Filter, decompression recycling ethanol, and 70 ℃ of surveys of simmer down to relative density is the clear paste of 1.2-1.35; By the conventional formulation technology of relevant dosage form, add appropriate amount of auxiliary materials and process corresponding dosage forms, promptly get.
(3) method for preparing three: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, powder is beaten in oven dry, mixing, and by the conventional formulation technology of relevant dosage form, the adding appropriate amount of auxiliary materials is processed corresponding dosage forms, promptly gets.
(4) method for preparing four: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca, Ganoderma are pressed percolation with the ethanol of 50%-85% respectively and extract, percolate, subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of clean back decocte with water 1-3 time, filter, remove slag the water extract, merging water extract; Be condensed into the clear paste that relative density is 1.03-1.15, put coldly, add ethanol, stir to containing alcohol amount 50%-75%; Leave standstill, filter, filtrating merges decompression recycling ethanol with percolate; And 70 ℃ of simmer down tos to survey relative density be the clear paste of 1.2-1.35, by the conventional formulation technology of relevant dosage form, add appropriate amount of auxiliary materials and process corresponding dosage forms, promptly get.
(5) method for preparing five: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca is pressed percolation with the ethanol of 50%-85% and is extracted, percolate, subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of add 50%-85% alcohol reflux 1-3 time after cleaning, filter; Merge alcohol extract, alcohol extract and percolate merge, decompression recycling ethanol; And 70 ℃ of surveys of simmer down to relative density is the clear paste of 1.2-1.35; By the conventional formulation technology of relevant dosage form, add appropriate amount of auxiliary materials and process corresponding dosage forms, promptly get.
(6) method for preparing six: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca, Ganoderma are pressed percolation with the ethanol of 50%-85% respectively and extract, percolate, reclaiming ethanol, to get the percolate clear paste subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of clean back decocte with water 1-3 time, filter; Remove slag the water extract, merge the water extract, and simmer down to survey relative density for 70 ℃ be the clear paste of 1.2-1.35; Merge with the percolate clear paste; By the conventional formulation technology of relevant dosage form, add appropriate amount of auxiliary materials and process corresponding dosage forms, promptly get.
Adjuvant described in the above-mentioned method for preparing is the adjuvant product that the relevant administration section's regulation of country can be applied to food, pharmaceutical production, comprises the food additive kind that meets national regulation and other the complementary composition except that raw material.
The specific embodiment
Embodiment 1.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 5g Radix Codonopsis 5g Formica fusca 10g Ganoderma 10g Poria 5g Herb Gynostemmae Pentaphylli 10g Radix Glycyrrhizae 3g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot, decocte with water is extracted 2 times; Filter, remove slag the water extract, merge the water extract, filtrating concentrates; 80 ℃ of drying under reduced pressure are pulverized, and add right amount of auxiliary materials, process tablet.
Embodiment 2.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 20g Radix Codonopsis 20g Formica fusca 15g Ganoderma 20g Poria 15g Herb Gynostemmae Pentaphylli 20g Radix Glycyrrhizae 8g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot, decocte with water is extracted 3 times, filters; Remove slag the water extract, merge the water extract, filtrating is concentrated into the clear paste that relative density is 1.03-1.15, puts coldly, adding ethanol is 60% to containing the alcohol amount; Stir, leave standstill, filter, decompression recycling ethanol, and 70 ℃ of surveys of simmer down to relative density is the clear paste of 1.3-1.35; 80 ℃ of drying under reduced pressure are pulverized, and add right amount of auxiliary materials, process granule.
Embodiment 3.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 10g Radix Codonopsis 15g Formica fusca 11g Ganoderma 15g Poria 10g Herb Gynostemmae Pentaphylli 15g Radix Glycyrrhizae 5g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot, decocte with water is extracted 1 time, filters; Remove slag the water extract, merge the water extract, filtrating is concentrated into the clear paste that relative density is 1.03-1.15, puts cold; Adding ethanol is 75% to containing the alcohol amount, stirs, and leaves standstill, and filters; Decompression recycling ethanol, and 70 ℃ of simmer down tos to survey relative density be the clear paste of 1.2-1.35,80 ℃ of drying under reduced pressure are pulverized; Add right amount of auxiliary materials, mixing is divided in Capsules or is sealed in the soft capsule material, and packing promptly gets hard capsule product or soft capsule product.
Embodiment 4.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 6g Radix Codonopsis 12g Formica fusca 15g Ganoderma 12g Poria 15g Herb Gynostemmae Pentaphylli 10g Radix Glycyrrhizae 3g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca, Ganoderma are pressed percolation with 50% ethanol respectively and extract, percolate, subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of clean back decocte with water 3 times, filter, remove slag the water extract; Merge the water extract, be condensed into the clear paste that relative density is 1.03-1.15, put coldly, add ethanol to containing alcohol amount 50%; Stir, leave standstill, filter, filtrating merges with percolate; Decompression recycling ethanol, and 70 ℃ of simmer down tos to survey relative density be the clear paste of 1.2-1.35, behind glyceryl monostearate heating and melting mixing; Splash in the not miscible condensed fluid, shrink condensation and process sphere or type spheric preparation, packing promptly gets drop pill.
Embodiment 5.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 10g Radix Codonopsis 10g Formica fusca 15g Ganoderma 15g Poria 15g Herb Gynostemmae Pentaphylli 15g Radix Glycyrrhizae 6g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca, Ganoderma are pressed percolation with 85% ethanol respectively and extract, percolate, subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of clean back decocte with water 2 times, filter, remove slag the water extract, merge the water extract; Be condensed into the clear paste that relative density is 1.03-1.15, put coldly, add ethanol, stir, leave standstill to containing alcohol amount 75%; Filter, filtrating merges with percolate, decompression recycling ethanol, and simmer down to survey relative density for 70 ℃ be the clear paste of 1.2-1.35,80 ℃ of drying under reduced pressure; Pulverize, add right amount of auxiliary materials, mixing, briquetting or adorn tea bag or fry in shallow oil in the bag then, packing promptly gets medicinal tea.
Embodiment 6.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 10g Radix Codonopsis 15g Formica fusca 15g Ganoderma 10g Poria 10g Herb Gynostemmae Pentaphylli 10g Radix Glycyrrhizae 5g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca is pressed percolation with 70% ethanol and is extracted, percolate, subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of add 65% alcohol reflux 2 times after cleaning, filter, and merge alcohol extract, and alcohol extract merges with percolate, decompression recycling ethanol, and simmer down to survey relative density for 70 ℃ be the clear paste of 1.2-1.35, the adding right amount of auxiliary materials is processed syrup.
Embodiment 7.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 10g Radix Codonopsis 5g Formica fusca 10g Ganoderma 15g Poria 5g Herb Gynostemmae Pentaphylli 20g Radix Glycyrrhizae 8g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca is pressed percolation with 50 ethanol and is extracted, percolate, subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of add 85% alcohol reflux 3 times after cleaning, filter, and merge alcohol extract; Alcohol extract and percolate merge, decompression recycling ethanol, and 70 ℃ of surveys of simmer down to relative density is the clear paste of 1.2-1.35; Add refined honey and receive cream, add an amount of antiseptic, packing promptly gets soft extract.
Embodiment 8.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 8g Radix Codonopsis 12g Formica fusca 12g Ganoderma 10g Poria 10g Herb Gynostemmae Pentaphylli 12g Radix Glycyrrhizae 6g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca, Ganoderma are pressed percolation with 75% ethanol respectively and extract, percolate, reclaiming ethanol, to get the percolate clear paste subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of clean back decocte with water 1 time, filter, remove slag the water extract; Merge the water extract, and simmer down to survey relative density for 70 ℃ be the clear paste of 1.2-1.35, merge with the percolate clear paste; 80 ℃ of drying under reduced pressure are pulverized, and add right amount of auxiliary materials; Mixing, water with 5% and Mel are done binding agent and are prepared into ball, and packing promptly gets pill.
Embodiment 9.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 10g Radix Codonopsis 15g Formica fusca 15g Ganoderma 15g Poria 5g Herb Gynostemmae Pentaphylli 15g Radix Glycyrrhizae 8g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, wherein Formica fusca, Ganoderma are pressed percolation with 50% ethanol respectively and extract, percolate, reclaiming ethanol, to get the percolate clear paste subsequent use; All the other raw medicinal materials of respectively distinguishing the flavor of clean back decocte with water 2 times, filter, remove slag the water extract, merge the water extract, and simmer down to survey relative density for 70 ℃ be the clear paste of 1.2-1.35, merge with the percolate clear paste, add right amount of auxiliary materials, process mixture.
Embodiment 10.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 8g Radix Codonopsis 10g Formica fusca 15g Ganoderma 15g Poria 5g Herb Gynostemmae Pentaphylli 12g Radix Glycyrrhizae 6g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, powder is beaten in oven dry, and mixing adds an amount of adjuvant, and the branch bag of packing into promptly gets powder.
Embodiment 11.
Take by weighing the raw material of Chinese medicine of following portions by weight: Radix Astragali 10g Radix Codonopsis 10g Formica fusca 15g Ganoderma 10g Poria 10g Herb Gynostemmae Pentaphylli 15g Radix Glycyrrhizae 6g.
Method for making: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot, decocte with water is extracted 3 times, filters, remove slag the water extract, merge the water extract, filtrating concentrates, the bag of packing into promptly gets.
The described adjuvant of the foregoing description is the adjuvant product that the relevant administration section's regulation of country can be applied to food, pharmaceutical production, comprises the food additive kind that meets national regulation and other the complementary composition except that raw material.
Substantive distinguishing features of the present invention and obvious improvement are:
1, the present invention is under the guidance of theory of Chinese medical science, with replenishing QI to invigorate the spleen, and strengthening vital QI to eliminate pathogenic factors; Diuretic is treated AIDS by the bonded Therapeutic Principle of wetting phase; Used for reference the achievement of modern pharmacology research simultaneously, filtered out the Chinese medicine that meets the rule of treatment of the present invention, made traditional Chinese medicine preparation product with obvious therapeutic effect.
2, the present invention's curative effect in clinical practice is obvious, and application and popularization value is high, and for improving the aids patient clinical symptoms, the existence quality of life effect that improves patient is remarkable.
The present invention treats the clinical trial data of the Chinese medicine preparation of AIDS:
Capsule with the present invention's preparation is observed the clinical efficacy of treatment AIDS.
Method:
Wu Jia medical institutions accomplish clinical observation in Guangxi.120 routine cases are divided into treatment group and matched group at random, and 60 examples are organized in treatment, use capsule treatment of the present invention, and matched group 60 examples are with ART (D4T+3TC+NVP).Treatment group and matched group tracking were synchronously followed up a case by regular visits to 6 months, collect the data of following index: safety indexes (blood, urine, just routine examination, liver, renal function are measured); Health giving quality observation index (clinical symptoms and sign situation of change are observed, and Carlow Paderewski integration situation of change is observed, and CD4+T lymphocyte situation of change is observed before and after the treatment).Statistical method: quantitative data adopts t check or variance analysis analysiss of testing, the analysis of testing of qualitative data employing chi-square criterion.Statistical software is SPSS 13.0.
The result:
1. two groups of case distribution situations:
Before the treatment; Object of study sex, route of infection, pattern of syndrome distribute, Carlow Paderewski integral distribution situation, through chi-square criterion, and two group differences there are no significant meaning (P＞0.05); The comparison of two groups of object of study age distribution, clinical symptoms and sign distributions, two groups of preceding CD4+T LCs of treatment; The t assay shows, the difference of various symptom and sign average integrals there are no significant meaning (P＞0.05) before treatment group and the treatment of control group, and baseline condition has comparability between two groups.
2. clinical observation on the therapeutic effect
Compare before symptom and sign integration after the treatment of two groups of object of study and the treatment; Heating, cough, major part such as weak all obviously reduce; Treatment group and matched group weak, indigestion and loss of appetite, breathe hard and the difference of lumbago integration has the significance meaning; The treatment group weak, indigestion and loss of appetite, breathe hard and the lumbago integration lower than matched group, the difference of other symptom and sign does not have the significance meaning; The difference of Carlow Paderewski integral distribution is through chi-square criterion before and after the treatment of treatment group; P＜0.001; Carlow Paderewski integration there was no significant difference (P＞0.05) behind the there was no significant difference (P＞0.064) before and after the treatment of control group, two groups of treatments is after the treatment; Two groups CD4+T LC all rises, and the CD4+T LC of treatment back treatment group is higher than matched group (P＜0.043).
3. safety detects index observing:
The conventional greatly equal no changes of unusual rate of treatment group and treatment of control group front and back three, treatment back treatment group have 1 example slightly rising of Aspartic Acid aminotransferase (AST) to occur; Matched group has 1 example the amino transaminase AST of alanine to occur slightly to raise, and 1 example ALT occurs and slightly raises, and the treatment group does not find that all serum creatinine (Cr) and serum urea nitrogen (BUN) take place unusually before and after the treatment; Matched group has 1 example BUN to occur slightly to raise.
Conclusion: this result of study shows; After the present invention uses 6 months; Except myalgia and menoxenia; Other symptom and signs (heating, cough, weak, indigestion and loss of appetite, suffer from diarrhoea, vomit, breathe hard, spontaneous perspiration, night sweat, feel sick, alopecia, headache, chest pain, stomachache, abdominal distention, arthralgia, lumbago, skin pruritus) all improve significantly; Wherein, weak, indigestion and loss of appetite, breathe hard and the curative effect of lumbago is superior to using merely antiviral agents (P＜0.05 or P＜0.001), to the curative effect of other symptom and signs with merely with antiviral agents there are no significant difference (P＞0.05).Treat after 6 months, the treatment group CD4+T lymphocyte 384.5/ml that on average rises is higher than the 364.3/ml (P＜0.05) of matched group.Carlow, treatment group treatment back Paderewski integration rises (P＜0.001), and Carlow Paderewski integration also rises after the treatment of control group, but does not reach significance, explains that the present invention uses the effect of improving Carlow Paderewski integration (quality of life) and is superior to matched group.
The comparison of Carlow Paderewski integration before and after the treatment
△: with comparison after the treatment of control group, through χ
2Check, P＞0.05.
LC before and after the treatment (individual/ml)
※: compare t=2.047, P=0.043 with matched group.
In sum, the present invention has the effect that improves AIDS related complex shape sign, improve weak, indigestion and loss of appetite, breathe hard and the effect of lumbago is superior to matched group.The effect that the present invention uses the quality of making the life better is superior to matched group.Do not find tangible untoward reaction in the clinical research.
Claims (2)
1. Chinese medicine preparation of treating AIDS is characterized in that it being the medicament of being processed by following method for preparing by the following weight proportion raw material:
Proportioning raw materials: Radix Astragali 10g Radix Codonopsis 15g Formica fusca 11g Ganoderma 15g Poria 10g Herb Gynostemmae Pentaphylli 15g Radix Glycyrrhizae 5g;
Method for preparing: get the Radix Astragali, Radix Codonopsis, Formica fusca, Ganoderma, Poria, Herb Gynostemmae Pentaphylli, Radix Glycyrrhizae and get the raw materials ready by proportioning, put in the extraction pot, decocte with water is extracted 1 time, filters; Remove slag the water extract, merge the water extract, filtrating is concentrated into the clear paste that relative density is 1.03-1.15, puts cold; Adding ethanol is 75% to containing the alcohol amount, stirs, and leaves standstill, and filters; Decompression recycling ethanol, and 70 ℃ of simmer down tos to survey relative density be the clear paste of 1.2-1.35,80 ℃ of drying under reduced pressure are pulverized; Add right amount of auxiliary materials, mixing is divided in Capsules or is sealed in the soft capsule material, and packing promptly gets hard capsule product or soft capsule product.
2. the purposes of the Chinese medicine preparation of treatment AIDS as claimed in claim 1 is characterized in that: the application of this Chinese medicine preparation in preparation treatment AIDS-treating medicine.
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| CN105250977A (en) * | 2015-11-19 | 2016-01-20 | 中国热带农业科学院热带生物技术研究所 | Traditional Chinese medicine composition for treating AIDS and preparation method thereof |
| CN105770431A (en) * | 2016-05-17 | 2016-07-20 | 唐天东 | Traditional Chinese medicine composition for treating AIDS and preparation method thereof |
| CN110898181A (en) * | 2019-12-18 | 2020-03-24 | 天津冠勤医药科技有限公司 | anti-AIDS medicine and its preparing method |
| CN118416165B (en) * | 2024-07-03 | 2024-08-23 | 中国中医科学院 | Chinese medicinal preparation for treating AIDS and its preparation method |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199672A (en) * | 2007-12-21 | 2008-06-18 | 北京中科雍和医药技术有限公司 | Chinese medicine health care wine containing function of regulating human body immunity |
-
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101199672A (en) * | 2007-12-21 | 2008-06-18 | 北京中科雍和医药技术有限公司 | Chinese medicine health care wine containing function of regulating human body immunity |
Non-Patent Citations (2)
| Title |
|---|
| 刘绍 等.食品免疫与免疫食品新进展.《实用预防医学》.2004,第11卷(第3期),第635－636页. * |
| 洒丽明.蚂蚁乙肝宁冲剂中黄芪甲甙的薄层扫描定量.《中成药》.1997,第19卷(第1期),第15-16页. * |
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| CN101810671A (en) | 2010-08-25 |
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