CN101805337A - 一类含脯氨酸和异恶唑骨架的化合物、其制备方法和用途 - Google Patents
一类含脯氨酸和异恶唑骨架的化合物、其制备方法和用途 Download PDFInfo
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- CN101805337A CN101805337A CN200910067850A CN200910067850A CN101805337A CN 101805337 A CN101805337 A CN 101805337A CN 200910067850 A CN200910067850 A CN 200910067850A CN 200910067850 A CN200910067850 A CN 200910067850A CN 101805337 A CN101805337 A CN 101805337A
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Landscapes
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Abstract
Description
化合物编号 | 化合物名称 |
I-1 | N-{{4-{[(3-苯基异恶唑-5-基)甲基]氧}苯基}甲基}-L-脯氨酸 |
I-2 | N-{{4-{[(3-(2-甲基苯基)异恶唑-5-基)甲基]氧}苯基}甲基}-L-脯氨酸 |
I-3 | N-{{4-{[(3-(3-氯苯基)异恶唑-5-基)乙基]氧}苯基}甲基}-L-脯氨酸 |
I-4 | N-{{4-{[(3-(3-硝基苯基)异恶唑-5-基)乙基]氧}苯基}甲基}-D-脯氨酸 |
I-5 | N-{{4-{[(3-(4-氰基苯基)异恶唑-5-基)乙基]氧}苯基}甲基}-D-脯氨酸 |
I-6 | N-{{4-{[(3-(2-甲氧基苯基)异恶唑-5-基)乙基]氧}苯基}甲基}-D-脯氨酸 |
化合物编号 | 化合物名称 |
I-7 | N-{{4-{[(3-(2-氯苯基)异恶唑-5-基)丙基]氧}苯基}甲基}-D-脯氨酸 |
I-8 | N-{{4-{[(3-(3-二甲氨基苯基)异恶唑-5-基)丙基]氧}苯基}甲基}-D-脯氨酸 |
I-9 | N-{{4-{[(3-(2-氯-3-氟苯基)异恶唑-5-基)乙基]氧}苯基}甲基}-L-脯氨酸 |
I-10 | N-{{4-{[(3-(2-氰基-3-甲基-4-硝基苯基)异恶唑-5-基)丙基]氧}苯基}甲基}-D-脯氨酸 |
Claims (9)
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CN2009100678502A CN101805337B (zh) | 2009-02-13 | 2009-02-13 | 一类含脯氨酸和异恶唑骨架的化合物、其制备方法和用途 |
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CN101805337A true CN101805337A (zh) | 2010-08-18 |
CN101805337B CN101805337B (zh) | 2012-05-23 |
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MXPA03010435A (es) * | 2001-05-15 | 2004-03-09 | Hoffmann La Roche | Derivados de oxazol acido carboxilico sustituidos para uso como activadores de proliferacion del peroximosa(ppar-alfa y gama) en el tratamiento de diabetes. |
TWI343915B (en) * | 2002-10-07 | 2011-06-21 | Hoffmann La Roche | Chirale ppar agonists |
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