CN101802966B - 质谱仪 - Google Patents

质谱仪 Download PDF

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Publication number
CN101802966B
CN101802966B CN2008801066691A CN200880106669A CN101802966B CN 101802966 B CN101802966 B CN 101802966B CN 2008801066691 A CN2008801066691 A CN 2008801066691A CN 200880106669 A CN200880106669 A CN 200880106669A CN 101802966 B CN101802966 B CN 101802966B
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CN
China
Prior art keywords
ion
electrode
trap device
collection
ion trap
Prior art date
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CN2008801066691A
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English (en)
Chinese (zh)
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CN101802966A (zh
Inventor
马丁·格伦
丹尼尔·詹姆斯·肯尼
大卫·兰格里奇
詹森·李·维尔德古斯
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Micromass UK Ltd
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Micromass UK Ltd
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Publication of CN101802966A publication Critical patent/CN101802966A/zh
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/426—Methods for controlling ions
    • H01J49/427—Ejection and selection methods
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H01J49/4205—Device types
    • H01J49/422—Two-dimensional RF ion traps
    • H01J49/4225—Multipole linear ion traps, e.g. quadrupoles, hexapoles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
CN2008801066691A 2007-07-12 2008-07-14 质谱仪 Active CN101802966B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0713590.8 2007-07-12
GBGB0713590.8A GB0713590D0 (en) 2007-07-12 2007-07-12 Mass spectrometer
US95197407P 2007-07-26 2007-07-26
US60/951,974 2007-07-26
PCT/GB2008/002402 WO2009007739A2 (en) 2007-07-12 2008-07-14 Mass spectrometer

Publications (2)

Publication Number Publication Date
CN101802966A CN101802966A (zh) 2010-08-11
CN101802966B true CN101802966B (zh) 2013-02-27

Family

ID=38461504

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2008801066691A Active CN101802966B (zh) 2007-07-12 2008-07-14 质谱仪

Country Status (7)

Country Link
US (3) US8426803B2 (cg-RX-API-DMAC7.html)
EP (3) EP2581928B1 (cg-RX-API-DMAC7.html)
JP (1) JP5301537B2 (cg-RX-API-DMAC7.html)
CN (1) CN101802966B (cg-RX-API-DMAC7.html)
CA (1) CA2692079C (cg-RX-API-DMAC7.html)
GB (2) GB0713590D0 (cg-RX-API-DMAC7.html)
WO (1) WO2009007739A2 (cg-RX-API-DMAC7.html)

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US8541737B2 (en) * 2009-11-30 2013-09-24 Battelle Memorial Institute System and method for collisional activation of charged particles
DE102010001349B9 (de) * 2010-01-28 2014-08-28 Carl Zeiss Microscopy Gmbh Vorrichtung zum Fokussieren sowie zum Speichern von Ionen
WO2012016330A1 (en) * 2010-08-04 2012-02-09 Dh Technologies Development Pte. Ltd. A linear ion trap for radial amplitude assisted transfer
WO2012025821A2 (en) * 2010-08-25 2012-03-01 Dh Technologies Development Pte. Ltd. Methods and systems for providing a substantially quadrupole field with significant hexapole and octapole components
GB201018184D0 (en) 2010-10-27 2010-12-08 Micromass Ltd Asymmetric field ion mobility in a linear geometry ion trap
WO2012067195A1 (ja) * 2010-11-19 2012-05-24 株式会社日立ハイテクノロジーズ 質量分析装置および質量分析方法
US8581177B2 (en) * 2011-04-11 2013-11-12 Thermo Finnigan Llc High duty cycle ion storage/ion mobility separation mass spectrometer
GB201114734D0 (en) 2011-08-25 2011-10-12 Micromass Ltd Mass spectrometer
GB201116026D0 (en) 2011-09-16 2011-10-26 Micromass Ltd Performance improvements for rf-only quadrupole mass filters and linear quadrupole ion traps with axial ejection
WO2013098600A1 (en) 2011-12-27 2013-07-04 Dh Technologies Development Pte Ltd Method of extracting ions with a low m/z ratio from an ion trap
US9368336B2 (en) 2013-01-31 2016-06-14 Beijing Institute Of Technology Ion trap-based apparatus and method for analyzing and detecting bipolar ions
CA2901378C (en) * 2013-02-18 2019-07-02 Micromass Uk Limited Improved efficiency and precise control of gas phase reactions in mass spectrometers using an auto ejection ion trap
CN104576288B (zh) * 2013-10-28 2017-02-08 北京理工大学 一种离子连续收集装置和方法、以及离子富集系统和方法
CN106373854B (zh) * 2015-07-23 2018-12-21 株式会社岛津制作所 一种离子导引装置
CN105632878B (zh) * 2016-01-01 2017-11-17 杭州谱育科技发展有限公司 四极杆质量分析器的工作方法
CN105869986B (zh) * 2016-05-04 2017-07-25 苏州大学 一种可提高离子探测效率的质谱分析系统
GB2558221B (en) * 2016-12-22 2022-07-20 Micromass Ltd Ion mobility separation exit transmission control
US10242857B2 (en) * 2017-08-31 2019-03-26 The University Of North Carolina At Chapel Hill Ion traps with Y-directional ion manipulation for mass spectrometry and related mass spectrometry systems and methods
GB2573485B (en) 2017-11-20 2022-01-12 Thermo Fisher Scient Bremen Gmbh Mass spectrometer
WO2020044160A1 (en) * 2018-08-29 2020-03-05 Dh Technologies Development Pte. Ltd. Method for top down proteomics using exd and ptr
US11087968B2 (en) 2018-12-14 2021-08-10 Thermo Finnigan Llc. Traveling wave multipole
KR102872760B1 (ko) 2019-09-25 2025-10-16 더 트러스티즈 오브 인디애나 유니버시티 펄스 모드 전하 검출 질량 분석을 위한 장치 및 방법
WO2021072186A1 (en) 2019-10-10 2021-04-15 The Trustees Of Indiana University System and method for identifying, selecting and purifying particles
US11201044B2 (en) 2020-03-03 2021-12-14 Thermo Finnigan Llc Multipole assembly configurations for reduced capacitive coupling
CA3264617A1 (en) * 2022-09-09 2024-03-14 The Trustees Of Indiana University METHOD FOR CONTROLLING A MULTIPOLAR DEVICE TO REDUCE THE OUTPUT OF CHARGED PARTICLES FROM A DOWNSTREAM ANALYSIS
CN119650129A (zh) * 2025-02-12 2025-03-18 吉林大学 一种高精度离子阱及其离子阱的组装方法

Citations (1)

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WO1998052209A1 (en) * 1997-05-12 1998-11-19 Mds Inc. Rf-only mass spectrometer with auxiliary excitation
US6504148B1 (en) * 1999-05-27 2003-01-07 Mds Inc. Quadrupole mass spectrometer with ION traps to enhance sensitivity
US6630662B1 (en) * 2002-04-24 2003-10-07 Mds Inc. Setup for mobility separation of ions implementing an ion guide with an axial field and counterflow of gas
DE10236346A1 (de) * 2002-08-08 2004-02-19 Bruker Daltonik Gmbh Nichtlinearer Resonanzauswurf aus linearen Ionenfallen
WO2004086441A2 (en) * 2003-03-21 2004-10-07 Dana-Farber Cancer Institute, Inc Mass spectroscopy system
JP4223937B2 (ja) * 2003-12-16 2009-02-12 株式会社日立ハイテクノロジーズ 質量分析装置
EP1704578B1 (en) 2004-01-09 2011-04-27 Micromass UK Limited Ion extraction devices and methods of selectively extracting ions
WO2006122412A1 (en) * 2005-05-18 2006-11-23 Mds Inc., Doing Business As Mds Sciex Method and apparatus for mass selective axial transport using quadrupolar dc
EP1944791B1 (en) * 2005-10-31 2015-05-06 Hitachi, Ltd. Mass-spectrometer and method for mass-spectrometry
JP5424085B2 (ja) * 2005-11-30 2014-02-26 エムディーエス インコーポレイテッド パルス軸方向場を使用した質量選択的軸方向輸送のための方法および装置
EP2038913B1 (en) 2006-07-10 2015-07-08 Micromass UK Limited Mass spectrometer
JP5081436B2 (ja) * 2006-11-24 2012-11-28 株式会社日立ハイテクノロジーズ 質量分析装置及び質量分析方法
US7633060B2 (en) 2007-04-24 2009-12-15 Thermo Finnigan Llc Separation and axial ejection of ions based on m/z ratio
GB0713590D0 (en) * 2007-07-12 2007-08-22 Micromass Ltd Mass spectrometer
KR101484297B1 (ko) 2007-08-31 2015-01-19 가부시키가이샤 한도오따이 에네루기 켄큐쇼 표시장치 및 표시장치의 제작방법

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Also Published As

Publication number Publication date
EP2581927A2 (en) 2013-04-17
WO2009007739A2 (en) 2009-01-15
US20130221242A1 (en) 2013-08-29
CA2692079A1 (en) 2009-01-15
CA2692079C (en) 2016-07-05
CN101802966A (zh) 2010-08-11
US8426803B2 (en) 2013-04-23
WO2009007739A3 (en) 2009-10-29
EP2581928B1 (en) 2018-09-19
EP2581927A3 (en) 2013-12-25
GB0713590D0 (en) 2007-08-22
JP5301537B2 (ja) 2013-09-25
EP2581928A3 (en) 2013-12-25
EP2168141A2 (en) 2010-03-31
EP2581927B1 (en) 2020-09-02
GB2455377B (en) 2010-04-28
EP2168141B1 (en) 2014-06-25
HK1145566A1 (en) 2011-04-21
GB0812827D0 (en) 2008-08-20
US8796615B2 (en) 2014-08-05
JP2010533353A (ja) 2010-10-21
EP2581928A2 (en) 2013-04-17
GB2455377A (en) 2009-06-10
US20140131568A1 (en) 2014-05-15
US8987661B2 (en) 2015-03-24
US20100252730A1 (en) 2010-10-07

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