CN101791332B - Compound gingko health product solid preparation - Google Patents
Compound gingko health product solid preparation Download PDFInfo
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- CN101791332B CN101791332B CN2010101417485A CN201010141748A CN101791332B CN 101791332 B CN101791332 B CN 101791332B CN 2010101417485 A CN2010101417485 A CN 2010101417485A CN 201010141748 A CN201010141748 A CN 201010141748A CN 101791332 B CN101791332 B CN 101791332B
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Abstract
The invention discloses a compound gingko health product solid preparation which is prepared by mixing ginkgo leaf extract, salvia miltiorrhiza bunge, American ginseng, seabuckthorn flavone and gelatin or an enteric substrate. The compound gingko health product solid preparation comprises the following effective components in parts by weight: 1-60 parts of ginkgo leaf extract, 1-60 parts of salvia miltiorrhiza bunge, 1-30 parts of American ginseng and 0.5-20 parts of seabuckthorn flavone. The gingko, the salvia miltiorrhiza bunge, the American ginseng and the seabuckthorn flavone are comprehensively mixed to achieve the effects of convenient use and comprehensive nourishing. The health product of the compound gingko health product solid preparation has values as both food and medicine and can be used by a patient with a cerebral-vascular disease and a patient with higher blood fat and used for resisting cancer, resisting fatigue, resisting anoxia, resisting radiation, resisting aging, strengthening immunity, and the like by a healthy person. The compound gingko health product solid preparation mainly has two formulations of pills and soft capsules, is convenient for use, is beneficial to absorption and meets the requirement on health by wide consumers.
Description
Technical field
The present invention relates to a kind of health product, is the basis with the integration of edible and medicinal herbs, is used to prevent and treat cardiovascular and cerebrovascular disease and enhancing immunity, is specially a kind of compound gingko health product solid preparation.
Background technology
Have 1.5 hundred million to be old people more than 60 years old in China's 1,300,000,000 populations approximately.Expect the year two thousand twenty, national old people will reach 2.43 hundred million, account for 17% of total population, and Chinese ageing phenomenon is serious day by day.The decline of middle-aged and elderly people multi-organ function nature, immunity degradation, " three-hypers disease "---be hypertension, hyperlipidemia, high blood clotting; The health and lives safety of middle-aged and elderly people in serious threat, and the heart and brain that cause therefrom, renal vascular disease to become be the major cause of morbidity that causes death.Current no doubt effective to " three-hypers disease " chemical drugs treatment, but the middle-aged and elderly people hepatic and renal function goes down, many diseases same usefulness of multiple medicines that is burdened with causes drug-induced disease, iatrogenic death thus simultaneously.The death that causes thus it is reported that the western countries in prosperity account for 18% of the dead person's sum of being admitted to hospital, and developing country is higher than this far away.The side effect that person in middle and old age's property disease that treatment by Chinese herbs " three-hypers disease ", immunity degradation cause can obviously avoid the chemical drugs treatment to be produced; And integration of edible and medicinal herbs is the elite place of motherland's medical science, and it is very necessary therefore to develop a kind of auxiliary treatment " three-hypers ", enhancing immunity and antidotal health food.Present product a multitude of names of relevant health care for the middle and old aged, but it is single all to exist curative effect, use inconvenient, be not easy to absorb, take effect and wait phenomenon slowly, and price is very high, is difficult to popularize.
Summary of the invention
To above-mentioned situation; For overcoming the prior art deficiency; The invention provides a kind of can enhancing immunity again can comprehensive prevention and the compound gingko health product solid preparation of treatment " three-hypers disease ", to satisfy the needs of people, promote to solve the health problem that people face to health product.The technical scheme of its solution is, according to the Chinese medicine principle, the present invention is a main component with Semen Ginkgo, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii and Fructus Hippophae flavone, and is equipped with other and helps the material that promotes that human life is healthy, thus enhancing human immune with improve the health of people level.
The present invention processes compound gingko health product solid preparation with Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone and gelatin or substrate proper fit, makes that it is more conducive to absorb, curative effect is more obvious.Because the course of disease and the character of disease are complicated and changeable, often cold and heat are staggered, and deficiency and excess is also seen; Counting disease for the moment all over the body holds concurrently mutually; Voucher kind health product are difficult to look after comprehensively, so must its proper fit be utilized its mutual working in coordination with or antagonism; Improve curative effect or reduce untoward reaction, with treatment and the daily health caring that adapts to the complicated state of an illness.
The dosage form of compound gingko health product solid preparation mainly contains two kinds of drop pill and soft capsules, and its absorbs rapidly, is the last word in the similar health-care food.
Technical scheme of the present invention: compound gingko health product solid preparation is Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone and gelatin or substrate to be carried out mixing preparation form.The weight ratio of said product effective ingredient (Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii and Fructus Hippophae flavone) is following: Folium Ginkgo extract: Radix Salviae Miltiorrhizae: Radix Panacis Quinquefolii: Fructus Hippophae flavone=(1-60) part: (1-60) part: (1-30) part: (0.5-20) part.
The present invention has confirmed further that to the proportioning ratio of described each component of compound gingko health product solid preparation the best proportion scope is on the basis of factors such as analysis-by-synthesis safety, production cost, convenient use, curative effect:
The further technical scheme of the present invention is: said compound gingko health product solid preparation is a soft capsule prepn, and said each set of dispense than (weight ratio) is:
Folium Ginkgo extract: Radix Salviae Miltiorrhizae: Radix Panacis Quinquefolii: Fructus Hippophae flavone: gelatin=(1.5-59) part: (1.5-59) part: (1.5-29.5) part: (0.5-19.5) part: (1-30) part.
The further technical scheme of the present invention is: said compound gingko health product solid preparation is a dropping pill formulation, and each set of dispense of said dropping pill formulation than (weight ratio) is:
Folium Ginkgo extract: Radix Salviae Miltiorrhizae: Radix Panacis Quinquefolii: Fructus Hippophae flavone: enteric substrate=(1.5-59) part: (1.5-59) part: (1.9-29.5) part: (0.5-19.5) part: (20-80) part.
Said enteric substrate can be medical polyethylene glycol 4000 and medical polyethylene glycol 6000.
The main component of Folium Ginkgo extract of the present invention is ginkgetin and bilobalide, and the quality percentage composition of said ginkgetin is 20-60%, and the quality percentage composition of said bilobalide is 0.5-6%.
The effective constituent effect of compound gingko health product solid preparation of the present invention is following:
Monarch is: Semen Ginkgo.Folium Ginkgo is used to treat uncomfortable in chest, pained, improves the heart and brain blood circulation, cholesterol reducing, improves symptoms such as hypertension.The tree root of ginkgo can be used for strengthening by means of tonics, improves weak body constitution.Semen Ginkgo has many magical curative effects, under the check of science excess syndrome, comprises the most significantly: blood circulation promoting, angiocardiopathy preventing; Memory reinforcing, the prevention Alzheimer; Antioxidation.No matter in Germany, the U.S., Japan or in the China's Mainland, also in coming out of the stove one after another, Folium Ginkgo also becomes the health food that many countries are in fashion about the research of Semen Ginkgo.
Minister is: Radix Salviae Miltiorrhizae." Radix Salviae Miltiorrhizae simply, merit is with four things " (Radix Rehmanniae, Radix Angelicae Sinensis, the Radix Paeoniae Alba, Rhizoma Chuanxiong), traditional medicine is thought: Radix Salviae Miltiorrhizae integrate nourish blood, invigorate blood circulation, blood stasis dispelling, pain relieving, tissue regeneration promoting blood, effect is remarkable and nature and flavor are gentle, the relieving restlessness that clears away heart-fire, has to mend and has diffusingly, has no side effect.Radix Salviae Miltiorrhizae mainly is corticocerebral inhibition to the effect of maincenter, produces sedation; The red sage formulation internal and external test has certain antitumor action.Merge with Radix Salviae Miltiorrhizae and radiotherapy clinically and be applied to tumor patient.Each extract of Radix Salviae Miltiorrhizae has tangible antibacterial and anti-inflammation functions.In a word Radix Salviae Miltiorrhizae have antioxidation, to the protective effect of cerebral tissue ischemia, reperfusion injury, strengthen hypoxia-bearing capability, improve renal function.
Assistant is: Radix Panacis Quinquefolii.Radix Panacis Quinquefolii has YIN nourishing and QI supplementing, the double effects that the mind calming and mentality promoting and clearing away heat and promoting production of body fluid, pathogenic fire reducing are relieved summer heat.The archaism cloud: " Radix Panacis Quinquefolii is cool in nature and mend, all desires do not receive with Radix Ginseng the warm person of Radix Ginseng all available it ".Radix Panacis Quinquefolii is a medicinal and edible plant, is famous and precious top grade Chinese medicine, is again the high-grade nourishing good merchantable brand, is confirmed as " the article list that can be used for health food " by Ministry of Public Health.Radix Panacis Quinquefolii has various pharmacological activities, as: have resisting fatigue, strong physique effect; Has additional needed by human body, the effect of human body immunity improving function; Have anti-hypoxia, high temperature resistance, anti-cold effect; Prevention and treatment cardiovascular and cerebrovascular disease; Have resisting myocardial ischemia and Antishock function, and obvious blood fat reducing; Have effects such as diuresis, calmness, hemostasis.Except daily health care, through clinical verification, Radix Panacis Quinquefolii also has certain curative effect to hypertension and cardiac muscular dystrophy, coronary heart disease, angina pectoris etc.Disease such as uncomfortable in chest, nervous vexed for being caused by heart disease is particularly suitable.Simultaneously, Radix Panacis Quinquefolii also can reduce " chemotherapy " or " radiotherapy " is controlled the untoward reaction that cancerous protuberance causes, Chang Zuowei treats the article of the adjuvant of various cancers.Mend and not dry be the special feature of Radix Panacis Quinquefolii.Radix Panacis Quinquefolii is nourished, sweet spring water in the lead body.Radix Panacis Quinquefolii is treated and is mended, and effect is outstanding.
Fructus Hippophae flavone is the main effective medicinal components of Fructus Hippophae in addition, and clinical medicine shows that Fructus Hippophae flavone isoreactivity material can reduce hypertension, vessel softening, prevents platelet aggregation, improves blood circulation, reduce cholesterol and triglyceride, the vessel softening in the blood, the deposit that prevents atherosclerosis, reduction blood viscosity, anticoagulant, reduction low density lipoprotein, LDL, removing blood vessel wall, recovery blood vessel elasticity, coronary blood flow increasing, reduction myocardial oxygen consumption, enhancing cardiac function etc.Fructus Hippophae flavone can play arrhythmia, resisting myocardial ischemia through removing reactive oxygen free radical, dwindles myocardial infarction area, allevating angina pectoris, improve the effect of cardiac function.
With Semen Ginkgo, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone and gelatin or substrate compatibility together, make the organic cooperation of each component, support mutually, the effect of the body-building of keeping fit is arranged, enhancing human immune is improved the cardiovascular and cerebrovascular vessel function, has no side effect.Health product of the present invention have edible and medicinal dual value, and are on probation through 3580 people (healthy subjects of the different crowd in age 50-70 year), three times on the one; Each eight (the soft capsule proportioning is seen embodiment 1, every 50mg, and the drop pill proportioning is seen embodiment 3; Every 50mg), soft capsule or the containing drop pill of swallowing.Divide 10 batches (initial Time of Administration be respectively 2005 6,7,8,10,11, December and 2006 1,2,3, April) take, every crowd 358 people cuts out after every crowd of user serve on 6 months, beginning statistical result.Statistical result is following: 3580 people in taking later 3 years of health product of the present invention only 25 people cold symptoms is arranged; Hypertension, hyperlipidemia or high blood clotting symptom appear in nobody; Also cardiovascular and cerebrovascular disease takes place in nobody; And with 3580 people under the condition not user's investigation statistics have 750 people various diseases take place, wherein have 285 people hypertension, hyperlipidemia or high blood clotting symptom to occur, cardiovascular and cerebrovascular disease appears in 253 people.Result of the test of the present invention clearlys show that the present invention has enhancing immunity, blood lipid regulation really, and the ideal effect with health of body of improving health is the creation on the health product.
Compound gingko health product solid preparation of the present invention is that Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone and gelatin or substrate are comprehensively allocated.Because take any component separately, its effect is single, can not reach the comprehensive health-care effect.Have only through comprehensive nourishing conditioning, the body of disorder is effectively taken good care of, could really solve " fatigue ", replenish vigour, make health reply health status.Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone and gelatin or substrate are carried out the compound compound gingko health product solid preparation that is deployed into; Can be widely used in cardio-cerebral vascular disease patient, the higher person of blood fat, and have multiple functions such as anticancer, resisting fatigue, anti-hypoxia, radioprotective, defying age, enhancing immunity.
Compound gingko health product solid preparation of the present invention can be processed with conventional health food processing method, can process two kinds of dosage forms of drop pill and soft capsule.Organic cooperation of each component of the present invention is supported mutually, and this invention can be used by cardio-cerebral vascular disease patient, the higher person of blood fat, and healthy person can use that it is anticancer, resisting fatigue, anti-hypoxia, radioprotective, defying age, enhancing immunity etc.Compound gingko health product solid preparation has drop pill and two kinds of dosage forms of soft capsule, and is easy to use, is beneficial to absorption, consumption rationally, be prone to produce, cost is low, mouthfeel good, has edible and medicinal dual value, has satisfied the demand of consumers in general to health.
The specific embodiment:
Embodiment 1, compound gingko health product solid preparation, select raw material for use: 45 parts of Folium Ginkgo extract, 35 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Panacis Quinquefoliis, 10 parts of Fructus Hippophae flavones, 10 parts of gelatin, during actual production, with dressing up soft capsule with conventional method behind the above raw material uniform mixing.
Embodiment 2, compound gingko health product solid preparation, select raw material for use: 40 parts of Folium Ginkgo extract, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Panacis Quinquefoliis, 15 parts of Fructus Hippophae flavones, 15 parts of gelatin, during actual production, with processing soft capsule with conventional method behind the above raw material uniform mixing.
Embodiment 3, compound gingko health product solid preparation; Select raw material for use: 45 parts of Folium Ginkgo extract, 35 parts of Radix Salviae Miltiorrhizaes, 10 parts of Radix Panacis Quinquefoliis, 10 parts of Fructus Hippophae flavones, 40 parts of enteric substrate (medical polyethylene glycol 4000 and medical polyethylene glycol 6000); During actual production, with processing drop pill with conventional method behind the above raw material uniform mixing.
Embodiment 4, compound gingko health product solid preparation; Select raw material for use: 40 parts of Folium Ginkgo extract, 30 parts of Radix Salviae Miltiorrhizaes, 15 parts of Radix Panacis Quinquefoliis, 10 parts of Fructus Hippophae flavones, 55 parts of enteric substrate (medical polyethylene glycol 4000 and medical polyethylene glycol 6000); During actual production, with processing drop pill with conventional method behind the above raw material uniform mixing.
Claims (5)
1. compound gingko health product solid preparation; It is characterized in that; It is to carry out mixing preparation by Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone and gelatin or substrate to form, and the weight ratio of said Folium Ginkgo extract, Radix Salviae Miltiorrhizae, Radix Panacis Quinquefolii, Fructus Hippophae flavone is: Folium Ginkgo extract: Radix Salviae Miltiorrhizae: Radix Panacis Quinquefolii: Fructus Hippophae flavone=(1-60) part: (1-60) part: (1-30) part: (0.5-20) part; The main component of said Folium Ginkgo extract is ginkgetin and bilobalide, and the quality percentage composition of said ginkgetin is 20-60%, and the quality percentage composition of said bilobalide is 0.5-6%.
2. compound gingko health product solid preparation according to claim 1 is characterized in that, said compound gingko health product solid preparation is dropping pill formulation or soft capsule prepn.
3. compound gingko health product solid preparation according to claim 2; It is characterized in that; Said compound gingko health product solid preparation is a soft capsule prepn, and each components by weight of said soft capsule prepn is: Folium Ginkgo extract: Radix Salviae Miltiorrhizae: Radix Panacis Quinquefolii: Fructus Hippophae flavone: gelatin=(1.5-59) part: (1.5-59) part: (1.5-29.5) part: (0.5-19.5) part: (1-30) part.
4. compound gingko health product solid preparation according to claim 2; It is characterized in that; Said compound gingko health product solid preparation is a drop pill, and each components by weight of said drop pill is a Folium Ginkgo extract: Radix Salviae Miltiorrhizae: Radix Panacis Quinquefolii: Fructus Hippophae flavone: enteric substrate=(1.5-59) part: (1.5-59) part: (1.9-29.5) part: (0.5-19.5) part: (20-80) part.
5. compound gingko health product solid preparation according to claim 4 is characterized in that, said enteric substrate is medical polyethylene glycol 4000 and polyethylene glycol 6000.
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| CN103169765A (en) * | 2013-03-26 | 2013-06-26 | 汉中永杨医药科技发展有限公司 | Eucommia ulmoides seed oil and red rice compound soft capsule preparation and preparation method thereof |
| CN103735621B (en) * | 2014-01-24 | 2017-01-04 | 中山珐玛斯医药科技有限公司 | A kind of Chinese medicine composition with blood fat reducing and enhancing immunity effect |
| CN104012971A (en) * | 2014-06-17 | 2014-09-03 | 史克勇 | Health care food capable of improving memory |
| CN107495367B (en) * | 2017-08-24 | 2020-11-20 | 四川省中医药科学院 | Food, health-care product or pharmaceutical composition for improving anoxia resistance and preparation method and application thereof |
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